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Do Insulin Pens Need To Be Refrigerated

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Get Familiar With The Xultophy® 100/3.6 Pen

WARNING: RISK OF THYROID C-CELL TUMORS Liraglutide, one of the components of Xultophy® 100/3.6, causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. It is unknown whether Xultophy® 100/3.6 causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of liraglutide-induced rodent thyroid C-cell tumors has not been determined. Xultophy® 100/3.6 is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk for MTC with the use of Xultophy® 100/3.6 and inform them of symptoms of thyroid tumors (e.g. a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with Xultophy® 100/3.6. Xultophy® 100/3.6 (insulin degludec and liraglutide injection) 100 units/mL and 3.6 mg/mL is a combination of insulin degludec and liraglutide and is indicated as an adjunct to diet and exercise to i Continue reading >>

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Popular Questions

  1. jfleetwd

    Do the unopened NovoLog flexpens need to be refrigerated? Same Q for Lantus SoloStar. Thanks?

    I am new to injecting insulin and am not sure if the FlexPens I'm using need to be refrigerated. I know that the one I'm using does not have to be for 28 days but the remaining ones in the box, I'm not sure about.

  2. RA Rajive Goel

    PenFill cartridges or NovoLog (insulin aspart [rdna origin] inj) FlexPen Prefilled Syringes:
    Once a cartridge or a NovoLog (insulin aspart [rdna origin] inj) FlexPen is punctured, it should be kept at temperatures below 30°C (86°F) for up to 28 days, but should not be exposed to excessive heat or sunlight. A NovoLog (insulin aspart [rdna origin] inj) FlexPen or cartridge in use must NOT be stored in the refrigerator. Keep the NovoLog (insulin aspart [rdna origin] inj) FlexPen and all PenFill cartridges away from direct heat and sunlight. Unpunctured NovoLog (insulin aspart [rdna origin] inj) FlexPen and PenFill cartridges can be used until the expiration date printed on the label if they are stored in a refrigerator. Keep unused NovoLog (insulin aspart [rdna origin] inj) FlexPen and PenFill cartridges in the carton so they will stay clean and protected from light.
    Always remove the needle after each injection and store the 3 mL PenFill cartridge elivery device or NovoLog (insulin aspart [rdna origin] inj) FlexPen without a needle attached. This prevents contamination and/or infection, or leakage of insulin, and will ensure accurate dosing. Always use a new needle for each injection to prevent contamination.
    Unopened Vial/Cartridge system/SoloStar disposable insulin device
    Unopened LANTUS (insulin glargine [rdna origin] injection) vials, cartridge systems and SoloStar should be stored in a refrigerator, 36°F - 46°F (2°C - 8°C). LANTUS (insulin glargine [rdna origin] injection) should not be stored in the freezer and it should not be allowed to freeze. Discard if it has been frozen.
    Open (In-Use) Vial
    Opened vials, whether or not refrigerated, must be used within 28 days after the first use. They must be discarded if not used within 28 days. If refrigeration is not possible, the open vial can be kept unrefrigerated for up to 28 days away from direct heat and light, as long as the temperature is not greater than 86°F (30°C). Open (In-Use) Cartridge system:
    The opened (in-use) cartridge system in OptiClik should NOT be refrigerated but should be kept at room temperature (below 86°F [30°C]) away from direct heat and light. The opened (in- use) cartridge system in OptiClik kept at room temperature must be discarded after 28 days. Do not store OptiClik , with or without cartridge system, in a refrigerator at any time.
    Open (In-Use) SoloStar disposable insulin device
    The opened (in-use) SoloStar should NOT be refrigerated but should be kept at room temperature (below 86°F [30°C]) away from direct heat and light. The opened (in-use) SoloStar kept at room temperature must be discarded after 28 days.
    LANTUS (insulin glargine [rdna origin] injection) should not be stored in the freezer and it should not be allowed to freeze. Discard if it has been frozen.
    I copied & pasted the information available for you to read & understand both the Insulin medications.
    Please take care, best wishes!
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