Pancreas | Pancreas Function | Pancreas Inflammation | Pancreas Location in Body is a quick video on What is pancreas - Pancreas function. The video elaborates on the Pancreas Definition and also elaborates on the functions of Pancreas like insulin secretion, other hormone secretion and Pancreatitis. What is pancreas - Pancreas function What is Pancreas? Pancreas is a compound gland, about 15 cm long that lies behind stomach. Its one end touches the spleen; the other end lies in the curve of duodenum. Pancreas is made up of clusters of specialized cells. Pancreas secretes a few hormones. The first one is ‘pancreatic juice’. The other one is ‘Insulin’, which is secreted by Islets of Langerhans. Pancreatic Juice secreted by Pancreas contains a number of enzymes concerned with digestion. This ‘Juice’ drains into small ducts that open into pancreatic ducts. This joins with the common bile duct and reaches the duodenum. Pancreatic juices contain a large amount of sodium bi carbonate for neutralizing the acidity of stomach contents. Pancreatic juices also contain Amylase, lipase maltase, trypsinogen and chymothypsinogen. The isolated group of cells called islets of Langerhans secretes Insulin and glucagons into the blood stream. The importance of pancreas lies in its output of Insulin. It is insulin that is the ‘key’ for the complex metabolism of food digestion, conversion to energy giving glucose and absorption by cells. When blood carrying Glucose reaches body cells, it alone cannot penetrate the body cells to supply glucose. Insulin is the ‘key’ that is required, if Insulin is not sufficient or not available, blood gets “jammed” with glucose and the giant of a disease, “Diabetes mellitus” is caused. Pancreatitis is inflammation of the Pancreas. The patient suffers serve pain in the back and upper abdomen. The cause for this disease is not yet established. It could be due to gall bladder stones or alcoholism. Chronic pancreatitis may cause malabsorption and diabetes mellitus. The treatment for pancreatitis consists of injecting the extract obtained from pancreas called pancreatin, intravenous feeding, drugs and surgery.
Pancreas And Insulin
Your pancreas is one of the organs of your digestive system. It lies in your abdomen, behind your stomach. It is a long thin structure with 2 main functions: producing digestive enzymes to break down food; and producing the hormones insulin and glucagon to control sugar levels in your body. Production of digestive enzymes The pancreas produces secretions necessary for you to digest food. The enzymes in these secretions allow your body to digest protein, fat and starch from your food. The enzymes are produced in the acinar cells which make up most of the pancreas. From the acinar cells the enzymes flow down various channels into the pancreatic duct and then out into the duodenum. The secretions are alkaline to balance the acidic juices and partially digested food coming into the duodenum from the stomach. Production of hormones to control blood sugar levels A small proportion (1-2 per cent) of the pancreas is made up of other types of cells called islets of Langerhans. These cells sit in tiny groups, like small islands, scattered throughout the tissue of the pancreas. The islets of Langerhans contain alpha cells which secrete glucagon and beta cells which secrete insulin. Insulin an
What is ACTION PLAN? What does ACTION PLAN mean? ACTION PLAN meaning - ACTION PLAN definition - ACTION PLAN explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. n action plan is a detailed plan outlining actions needed to reach one or more goals. Alternatively, businessdictionary.com defines an action plan as a "sequence of steps that must be taken, or activities that must be performed well, for a strategy to succeed". Producing an action plan can be beneficial not only for individual basis but also for businesses. For example, it allows project managers or any member of a group to monitor their progress and take each task step-by-step, therefore allowing them to handle the project efficiently. The advantage of doing this is, it allows you to execute a structured plan for the end goal you intend to achieve. Furthermore, it provides the team with appropriate foundations, therefore prioritising the amount of time you spend on each task. This will then prevent any sidetracking that may occur. Lastly, it creates a bond within a team, as each member is aware of their individual role, as well as providing necessary information to ensure success of the project. When using action plans limitations will need to be considered. Firstly, each member of the team will need to be allocated individual roles and tasks which will require completion by a set date. This can be demanding for some, due to coping with the stress and distractions that may occur. Another issue is not being guided thoroughly and effectively, leading to the lack of effort and passion a member has for the project. In addition to this, if the communication throughout the team is non-existent, key information will not reach members of the group, causing lack of confidence. Lastly failing to obtain the goal you set to reach can lead to frustration and in turn the planning would have been a waste of time. There can be more addition to this article. An action plan is a tool in social planning. It is an organizational strategy to identify necessary steps towards a goal. It considers details, may help limit setting for an organization, and is efficient in that it is saving resources over trial and error. A written action plan also serves as a token for an organization's accountability. When creating action plans there are guided steps that need to be followed to ensure success, however the structure can be altered in the process. Firstly, you will need to outline what you want to achieve from the project, by doing this you set yourself targets. After this the specific roles will need to be allocated ensuring sufficient amount of training, resources and issues have been considered to ensure solving any problems that may occur. The next stage allows members of the group to analyse the progress by outlining milestones, solving any issues and making any necessary changes. Lastly once the project has come to an end the final stage can be examined to ensure future success.
Handbook Of Diabetes, 4th Edition, Excerpt #4: Normal Physiology Of Insulin Secretion And Action
Insulin is synthesized in and secreted from the β-cells within the islets of Langerhans in the pancreas. The normal pancreas has about 1 million islets, which constitute about 2-3% of the gland’s mass. All of the islet cell types are derived embryologically from endodermal outgrowths of the fetal gut. The islets can be identified easily with various histological stains, such as hematoxylin and eosin (Figure 5.1), with which the cells react less intensely than does the surrounding exocrine tissue. The islets vary in size from a few dozen to several thousands of cells and are scattered irregularly throughout the exocrine pancreas…. The main cell types of the pancreatic islets are β-cells that produce insulin, α-cells that secrete glucagon, δ cells that produce somatostatin and PP cells that produce pancreatic polypeptide. The different cell types can be identified by immunostaining techniques, in situ hybridization for their hormone products (using nucleotide probes complementary to the target mRNA) and the electron microscope appearance of their secretory granules. The β-cells are the most numerous cell type and are located mainly in the core of the islet, while α and δ c
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A Unifying Organ Model Of Pancreatic Insulin Secretion
Abstract The secretion of insulin by the pancreas has been the object of much attention over the past several decades. Insulin is known to be secreted by pancreatic β-cells in response to hyperglycemia: its blood concentrations however exhibit both high-frequency (period approx. 10 minutes) and low-frequency oscillations (period approx. 1.5 hours). Furthermore, characteristic insulin secretory response to challenge maneuvers have been described, such as frequency entrainment upon sinusoidal glycemic stimulation; substantial insulin peaks following minimal glucose administration; progressively strengthened insulin secretion response after repeated administration of the same amount of glucose; insulin and glucose characteristic curves after Intra-Venous administration of glucose boli in healthy and pre-diabetic subjects as well as in Type 2 Diabetes Mellitus. Previous modeling of β-cell physiology has been mainly directed to the intracellular chain of events giving rise to single-cell or cell-cluster hormone release oscillations, but the large size, long period and complex morphology of the diverse responses to whole-body glucose stimuli has not yet been coherently explained. Start
1. Diabetes Care. 2004 Jun;27(6):1439-46. Impaired insulin sensitivity, insulin secretion, and glucose effectivenesspredict future development of impaired glucose tolerance and type 2 diabetes inpre-diabetic African Americans: implications for primary diabetes prevention. Osei K(1), Rhinesmith S, Gaillard T, Schuster D. (1)Ohio State University College of Medicine and Public Health, 491 McCampbell Hall, Columbus, OH 43210, USA. [email protected] ...
Sort Which of the following is a feature of an endocrine gland? -secretes a hormone directly into the bloodstream -secretes a hormone into a gland or duct -the product of these glands is carried into the lumen of an organ -characterized by the salivary glands -they do not respond to a negative feedback system Secretes a hormone directly into the bloodstream Which of the following organs also produce hormones as a secondary function of the organ? ...
Due to rising obesity and insulin resistance rates, low-carb and Paleo diets have become a popular approach to the growing population of overweight Americans. As stated by Dr. John McDougall, "Advocates of high-protein diets explain the reason people are fat is not because of the fat they eat, but because of hyperinsulinism and insulin resistance. Insulin encourages fat cells to store fat and prevents the release of fat from these cells. Therefor ...
Diabetics need insulin therapy because they can't make their own. Insulin therapy tries to mimic natural insulin secretion — what happens automatically in non-diabetics. The ultimate goal of insulin therapy is to mimic normal insulin levels. Unfortunately, current insulin replacement therapy can only approximate normal insulin levels. Insulin therapy for type 2 diabetes ranges from one injection a day to multiple injections and using an insulin ...
1. The Dual Nature of the Pancreas The pancreas is a complex gland active in digestion and metabolism through secretion of digestive enzymes from the exocrine portion and hormones from the endocrine portion. The exocrine pancreas, which accounts for more than 95% of the pancreas mass, is structurally comprised of lobules, with acinar cells surrounding a duct system. The endocrine pancreas makes up only 2% of the pancreatic mass and is organized i ...
The goal of insulin therapy is to achieve optimal blood glucose control. Healthy, non-diabetic individuals usually maintain a blood glucose profile of 60 – 100 mg/dl overnight and before meals, and <140 mg/dl after meals. Specific blood glucose levels for diabetics are controversial but health providers often recommend overnight and pre-meal blood glucose of <90-130 mg/dl and post-meal blood glucose of <180 mg/dl.• Normally the pancreas secre ...