diabetestalk.net

Cloudy Insulin Preparations

Steps For Preparing A Mixed Dose Of Insulin

Steps For Preparing A Mixed Dose Of Insulin

XIAFLEX® is a prescription medicine used to treat adults with Dupuytren's contracture when a "cord" can be felt. It is not known if XIAFLEX® is safe and effective in children under the age of 18. Do not receive XIAFLEX® if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX®, or to any other collagenase product. See the end of the Medication Guide for a complete list of ingredients in XIAFLEX®. XIAFLEX® can cause serious side effects, including: Tendon rupture or ligament damage. Receiving an injection of XIAFLEX® may cause damage to a tendon or ligament in your hand and cause it to break or weaken. This could require surgery to fix the damaged tendon or ligament. Call your healthcare provider right away if you have trouble bending your injected finger (towards the wrist) after the swelling goes down or you have problems using your treated hand after your follow-up visit Nerve injury or other serious injury of the hand. Call your healthcare provider right away if you get numbness, tingling, increased pain, or tears in the skin (laceration) in your treated finger or hand after your injection or after your follow-up visit Hypersensitivity reactions, including anaphylaxis. Severe allergic reactions can happen in people who receive XIAFLEX® because it contains foreign proteins. Call your healthcare provider right away if you have any of these symptoms of an allergic reaction after an injection of XIAFLEX®: hives swollen face breathing trouble chest pain low blood pressure Increased chance of bleeding. Bleeding or bruising at the injection site can happen in people who receive XIAFLEX®. Talk to your healthcare provider if you have a problem with your blood clotting. XIAFLEX® may not be right for you. Befor Continue reading >>

How Do I Prepare A Mixed Insulin Injection?

How Do I Prepare A Mixed Insulin Injection?

How do I prepare a mixed insulin injection? To prepare a mixed insulin injection, follow these steps: Be clear on the amounts of each insulin and the totalunits you want. To find the total units, add the units ofrapid- or short-acting insulin to the units of intermediate-or long-acting insulin. For cloudy insulin, gently roll the bottle of insulin slowlybetween your palms to mix. Make sure it is mixed thoroughly.Do not use if it has clumps or particles in it.Shaking the bottle can cause air bubbles. Draw air into the syringe equal to the intermediate- orlong-acting dose. Hold the bottle steady on the table and put the needlethrough the rubber stopper. Inject the air into that bottle.Take out the needle without drawing up any insulin. Draw air into the syringe equal to the dose of rapid- orshort-acting insulin and inject the air into the bottle ofrapid- or short-acting insulin. With the needle still in the rapid- or short-acting insulinbottle, turn it upside down so that insulin covers the tipof the needle. Pull the correct amount of insulin into the syringe bypulling back on the plunger. Check for air bubbles in the syringe. If you see air bubbles, keep the bottle upsidedown and push the plunger up so the insulin goes backinto the bottle. If necessary, empty and refill until all airbubbles in the syringe are gone. Remove the syringe. Insert the syringe into the bottle of intermediate- or long-actinginsulin. (You have already injected the rightamount of air into this bottle.) Slowly pull the plunger down to draw in the right dosageof intermediate- or long-acting insulin. This will be thetotal units of the short- and intermediate- or long-actinginsulins. Do not return any extra insulin back to this bottle. Itsnow a mixture. Double check for the correct totalamount of ins Continue reading >>

Insulin: How To Give A Mixed Dose

Insulin: How To Give A Mixed Dose

Many people with diabetes need to take insulin to keep their blood glucose in a good range. This can be scary for some people, especially for the first time. The truth is that insulin shots are not painful because the needles are short and thin and the insulin shots are placed into fatty tissue below the skin. This is called a subcutaneous (sub-kyu-TAY-nee-us) injection. In some cases, the doctor prescribes a mixed dose of insulin. This means taking more than one type of insulin at the same time. A mixed dose allows you to have the benefits of both short-acting insulin along with a longer acting insulin — without having to give 2 separate shots. Usually, one of the insulins will be cloudy and the other clear. Some insulins cannot be mixed in the same syringe. For instance, never mix Lantus or Levemir with any other solution. Be sure to check with your doctor, pharmacist, or diabetes educator before mixing. These instructions explain how to mix two different types of insulin into one shot. If you are giving or getting just one type of insulin, refer to the patient education sheet Insulin: How to Give a Shot. What You Will Need Bottles of insulin Alcohol swab, or cotton ball moistened with alcohol Syringe with needle (You will need a prescription to buy syringes from a pharmacy. Check with your pharmacist to be sure the syringe size you are using is correct for your total dose of insulin.) Hard plastic or metal container with a screw-on or tightly-secured lid Parts of a Syringe and Needle You will use a syringe and needle to give the shot. The parts are labeled below. Wash the work area (where you will set the insulin and syringe) well with soap and water. Wash your hands. Check the drug labels to be sure they are what your doctor prescribed. Check the expiration date o Continue reading >>

Types Of Insulin | Cs Mott Children's Hospital | Michigan Medicine

Types Of Insulin | Cs Mott Children's Hospital | Michigan Medicine

24 hours or more (glargine), 42 hours or more (degludec) Mixtures of insulin can sometimes be combined in the same syringe, for example, intermediate-acting and rapid- or short-acting insulin. Not all insulins can be mixed together. For convenience, there are premixed rapid- and intermediate-acting insulin. The insulin will start to work as quickly as the fastest-acting insulin in the combination. It will peak when each type of insulin typically peaks, and it will last as long as the longest-acting insulin. Examples include: 70% NPH and 30% regular (Humulin 70/30, Novolin 70/30). 50% lispro protamine and 50% lispro (Humalog Mix 50/50). 75% lispro protamine and 25% lispro (Humalog Mix 75/25). 70% aspart protamine and 30% aspart (NovoLog Mix 70/30). Insulin degludec injection (2015). Facts and Comparisons eAnswers. Accessed December 30, 2015. Insulin detemir injection (2014). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin glargine (rDNA origin) injection (2015). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin glulisine (rDNA origin) injection (2014). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin isophane (NPH)/insulin regular injection (2013). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin isophane injection (2014). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin lispro injection (2014). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin regular (human) inhalation (2015). Facts and Comparisons eAnswers. Accessed May 13, 2015. Insulin regular (human) injection (2015). Facts and Comparisons eAnswers. Accessed May 13, 2015. Continue reading >>

Proper Use

Proper Use

Drug information provided by: Micromedex Make sure you have the type (beef and pork, pork, or human) and the strength of insulin that your doctor ordered for you. You may find that keeping an insulin label with you is helpful when buying insulin supplies. The concentration (strength) of insulin is measured in USP Insulin Units and USP Insulin Human Units and is usually expressed in terms such as U-100 insulin. Insulin doses are measured and injected with specially marked insulin syringes. The appropriate syringe is chosen based on your insulin dose to make measuring the dose easy to read. This helps you measure your dose accurately. These syringes come in three sizes: 3/10 cubic centimeters (cc) measuring up to 30 USP Units of insulin, ½ cc measuring up to 50 USP Units of insulin, and 1 cc measuring up to 100 USP Units of insulin. It is important to follow any instructions from your doctor about the careful selection and rotation of injection sites on your body. There are several important steps that will help you successfully prepare your insulin injection. To draw the insulin up into the syringe correctly, you need to follow these steps: Wash your hands with soap and water. If your insulin contains zinc or isophane (normally cloudy), be sure that it is completely mixed. Mix the insulin by slowly rolling the bottle between your hands or gently tipping the bottle over a few times. Never shake the bottle vigorously (hard). Do not use the insulin if it looks lumpy or grainy, seems unusually thick, sticks to the bottle, or seems to be even a little discolored. Do not use the insulin if it contains crystals or if the bottle looks frosted. Regular insulin (short-acting) should be used only if it is clear and colorless. Remove the colored protective cap on the bottle. Do not Continue reading >>

How To Prepare Two Types Of Insulin In One Syringe

How To Prepare Two Types Of Insulin In One Syringe

A step-by-step guide to combine two types of insulin in a single syringe People with diabetes may be prescribed two types of insulin to be taken at the same time. To reduce the number of insulin injections, it is common to combine two types of insulin in a single syringe using r apid-acting (clear) insulin witheither an intermediate or a long-acting ( cloudy) insulin. Follow These Steps to Prepare the Injection:

  1. Prepare your supplies and remove the insulin vials from the fridge half an hour before your injection. Check their expiry dates. Discard the vial six weeks after opening or as per the manufacturers guide.
  1. Wash your hands with water and soap.
  1. Roll the vial of cloudy insulin (intermediate or long-acting insulin) until the white powder has dissolved. Do NOT shake the vial.
  1. Clean the rubber stopper of the insulin vials with an alcohol wipe or a cotton ball dipped in alcohol.
  1. Draw air into the syringe by pulling the plunger down. The amount of air drawn should be equal to the dose of cloudy insulin that you require.
  1. With the vial standing upright, insert the needle into the vial containing the cloudy insulin. Inject air into the vial and remove the needle.
  1. Repeat the steps with clear insulin. Draw air into the syringe that is equal to the dose of clear insulin you require.
  1. Insert the needle into the vial containing the clear insulin and inject air into the vial. Do NOT remove the needle.
  1. With the needle in the vial, turn the syringe and insulin vial upside down, and draw out your dose of clear Continue reading >>

Types Of Insulin

Types Of Insulin

Topic Overview Insulin is used to treat people who have diabetes. Each type of insulin acts over a specific amount of time. The amount of time can be affected by exercise, diet, illness, some medicines, stress, the dose, how you take it, or where you inject it. Insulin strength is usually U-100 (or 100 units of insulin in one millilitre of fluid). Short-acting (regular) insulin is also available in U-500. This is five times more concentrated than U-100 regular insulin. Long-acting insulin (glargine) is also available in U-300. This is three times more concentrated than U-100 long-acting insulin. Be sure to check the concentration of your insulin so you take the right amount. Insulin is made by different companies. Make sure you use the same type of insulin consistently. Types of insulinfootnote 1 Type Examples Appearance When it starts to work (onset) The time of greatest effect (peak) How long it lasts (duration) Rapid-acting Apidra (insulin glulisine) Clear 10-15 minutes 1-1.5 hours 3-5 hours Humalog (insulin lispro) Clear 10-15 minutes 1-2 hours 3.5-4.75 hours NovoRapid (insulin aspart) Clear 10-15 minutes 1-1.5 hours 3-5 hours Short-acting Humulin R, Novolin ge Toronto (insulin regular) Clear 30 minutes 2-3 hours 6.5 hours Intermediate-acting Humulin N, Novolin ge NPH(insulin NPH) Cloudy 1-3 hours 5-8 hours Up to 18 hours Long-acting Lantus (insulin glargine) Clear 1.5 hours Does not apply Up to 24 hours Levemir (insulin detemir) Clear 1.5 hours Does not apply 16 to 24 hours Toujeo (insulin glargine U-300) Clear Up to 6 hours Does not apply Up to 30 hours Rapid-acting insulins work over a narrow, more predictable range of time. Because they work quickly, they are used most often at the start of a meal. Rapid-acting insulin acts most like insulin that is produced by Continue reading >>

Insulin Administration

Insulin Administration

Insulin is necessary for normal carbohydrate, protein, and fat metabolism. People with type 1 diabetes mellitus do not produce enough of this hormone to sustain life and therefore depend on exogenous insulin for survival. In contrast, individuals with type 2 diabetes are not dependent on exogenous insulin for survival. However, over time, many of these individuals will show decreased insulin production, therefore requiring supplemental insulin for adequate blood glucose control, especially during times of stress or illness. An insulin regimen is often required in the treatment of gestational diabetes and diabetes associated with certain conditions or syndromes (e.g., pancreatic diseases, drug- or chemical-induced diabetes, endocrinopathies, insulin-receptor disorders, certain genetic syndromes). In all instances of insulin use, the insulin dosage must be individualized and balanced with medical nutrition therapy and exercise. This position statement addresses issues regarding the use of conventional insulin administration (i.e., via syringe or pen with needle and cartridge) in the self-care of the individual with diabetes. It does not address the use of insulin pumps. (See the American Diabetes Association’s position statement “Continuous Subcutaneous Insulin Infusion” for further discussion on this subject.) INSULIN Insulin is obtained from pork pancreas or is made chemically identical to human insulin by recombinant DNA technology or chemical modification of pork insulin. Insulin analogs have been developed by modifying the amino acid sequence of the insulin molecule. Insulin is available in rapid-, short-, intermediate-, and long-acting types that may be injected separately or mixed in the same syringe. Rapid-acting insulin analogs (insulin lispro and insulin a Continue reading >>

What Drugs Can You Do With The Orange Insulin Needles?

What Drugs Can You Do With The Orange Insulin Needles?

The insulin syringes are used for most of the IV drugs. This includes meth, heroin, cocaine, ketamine, DMT, and most water soluable drugs. There are drugs that are taken intramuscularly with the large 3mil syringes. Most people are not really aware of these, they are niche drugs like DBol and similar substances. I have a friend who cycles test and DBol and when he brought out his syringes I thought he was trying to make a rabies shot. The needle must have been a 19 gauge or something. It looked like a spear. Anyway, the drug that's being taken intravenously with the 28 or 29 gauge insulin syringes can normally be identified by the process of preparing the dose. With heroin, the user will put the water in a little metal cup and add the drug to it. They will then heat it with a flame until it's all dissolved. They then add a ball of cotton and draw up a brownish liquid into the syringe. With meth the drug is mixed with water and stirred until it is all dissolved. The cotton is sometimes used but not necessary in most cases. The liquid is clear. With cocaine it is prepared like heroin but the liquid is clear or slightly off white. Ketamine is prepared like meth but it can be used IM, SC, and IV without any problems. Meth can only be done IV. Ketamine is an offwhite color which appears cloudy. Continue reading >>

Insulin And Diabetes

Insulin And Diabetes

Insulin injections are required when the body produces little or no insulin, as with type 1 diabetes . They are also required for some people with type 2 diabetes when diabetes tablets, together with healthy eating and regular physical activity, are not enough to control blood glucose levels. Insulin is a hormone made by special cells, called beta cells, in the pancreas. When we eat, insulin is released into the blood stream where it helps to move glucose from the food we have eaten into cells to be used as energy. Insulin also helps store excess glucose in the liver. While ways of taking insulin by mouth or as a nasal spray are being developed, they are yet to become readily available. Insulin cannot be given in tablet form as the stomach would digest it, just as it digests food. For people with type 2 diabetes, starting on insulin can be a difficult and frightening decision to make. However, the many injection devices and tiny needles available today make injecting insulin much easier than most people imagine. In fact many say that they can feel the finger prick for monitoring blood glucose more than they can feel the needle used to inject insulin. When starting on insulin, your doctor and diabetes educator will help you adjust to the new routine. You may find that even with their help, it may take a while to find exactly the right dose to reduce your blood glucose to acceptable levels and to suit your particular lifestyle. There are 5 types of insulin ranging from short to long acting as insulin is classified according to how long it works in the body. Some insulins are clear in appearance, others cloudy. Everyone is different and will respond differently to the insulin they take. Therefore, many people need varying amounts of both a short and longer acting insulin. Continue reading >>

Insulin In The Uk

Insulin In The Uk

Tweet Insulin may be a key part of your treatment if you suffer from diabetes. Insulin enables your body to use glucose. Different types of insulin can act very differently in different people. Insulin regime suitable for individual patients are tailored by your diabetes care team. Type or dosage of insulin can be changed if required to meet the individual needs of the patient. Insulin can be packaged in vials (bottles), cartridges or prefilled pens. The vials are used with syringes, whereas the cartridges are used with pen injectors. Prefilled pens are disposable pen injectors, which contain insulin. Prefilled pens are useful for people with dexterity or visual problems. List of insulins The table highlights the various insulin types, their manufacturers, the insulin source and how it's available. It also highlights insulin ranges that have been discontinued. Insulin type Name Manufacturer Type Source Rapid-acting analogue Apidra Sanofi analogue vial & cartridge Apidra Sanofi analogue prefilled pen Humalog Lilly analogue vial & cartridge Humalog Lilly analogue prefilled pen Novorapid Novo Nordisk analogue vial Novorapid Penfill Novo Nordisk analogue cartridge Novorapid Novolet Novo Nordisk analogue prefilled pen Long-acting analogue Lantus Sanofi analogue vial, cartridge & prefilled pen Levemir Novo Nordisk analogue cartridge & prefilled pen Tresiba Novo Nordisk analogue cartridge & prefilled pen Short-acting Human Actrapid Novo Nordisk human vial Actrapid Pen* Novo Nordisk human prefilled pen Actrapid Penfill* Novo Nordisk human cartridge Human Velosulin* Novo Nordisk human vial Pork Actrapid* Novo Nordisk pork vial Humaject S* Lilly human prefilled pen Humulin S Lilly human vial & cartridge Hypurin Bovine Neutral CP Pharmaceuticals beef vial & cartridge Hypurin Porci Continue reading >>

Insulin Basics | Ce Article | Nursingcenter

Insulin Basics | Ce Article | Nursingcenter

May/June 2017, Volume 15 Number 3 , p 30 - 35 This article has an associated Continuing Education component. Keep your patients safe with this must-know information. Over 29 million Americans have diabetes, according to the CDC. Another 86 million have prediabetes. Of these individuals, it's estimated that approximately 6 million take insulin. Administration of this medication carries some significant safety risks. We discuss these safety concerns and your role in patient monitoring and education. But first, let's review insulin's role in the body and the types of insulin available. Insulin is an essential hormone produced and secreted by the pancreas that helps cells use glucose for energy. Inside the pancreas are clusters of cells known as islets. Beta cells within the islets are responsible for making insulin and releasing it into the bloodstream. When a person eats carbohydrates, the body breaks them down into the simple sugar glucose, which is then used as the body's main energy source. As circulating glucose levels in the bloodstream rise, the pancreas releases insulin, which helps the glucose enter the cells. When insulin is released into the bloodstream, it comes into contact with the cell membrane and combines with a receptor that allows glucose transporters to be activated. Think of insulin as the key that opens up the cell so that glucose can enter. With type 1 diabetes mellitus, the body doesn't make insulin because the beta cells within the pancreas have been destroyed. These individuals require insulin administration for the rest of their lives. With type 2 diabetes mellitus, insulin is made in the pancreas, but the body doesn't respond well to it. These individuals may require an oral medication, insulin, or a combination of both. Be aware that insulin c Continue reading >>

Types Of Insulin

Types Of Insulin

Insulin analogs are now replacing human insulin in the US. Insulins are categorized by differences in onset, peak, duration, concentration, and route of delivery. Human Insulin and Insulin Analogs are available for insulin replacement therapy. Insulins also are classified by the timing of their action in your body – specifically, how quickly they start to act, when they have a maximal effect and how long they act.Insulin analogs have been developed because human insulins have limitations when injected under the skin. In high concentrations, such as in a vial or cartridge, human (and also animal insulin) clumps together. This clumping causes slow and unpredictable absorption from the subcutaneous tissue and a dose-dependent duration of action (i.e. the larger dose, the longer the effect or duration). In contrast, insulin analogs have a more predictable duration of action. The rapid acting insulin analogs work more quickly, and the long acting insulin analogs last longer and have a more even, “peakless” effect. Background Insulin has been available since 1925. It was initially extracted from beef and pork pancreases. In the early 1980’s, technology became available to produce human insulin synthetically. Synthetic human insulin has replaced beef and pork insulin in the US. And now, insulin analogs are replacing human insulin. Characteristics of Insulin Insulins are categorized by differences in: Onset (how quickly they act) Peak (how long it takes to achieve maximum impact) Duration (how long they last before they wear off) Concentration (Insulins sold in the U.S. have a concentration of 100 units per ml or U100. In other countries, additional concentrations are available. Note: If you purchase insulin abroad, be sure it is U100.) Route of delivery (whether they a Continue reading >>

Types Of Insulin For Diabetes Treatment

Types Of Insulin For Diabetes Treatment

Many forms of insulin treat diabetes. They're grouped by how fast they start to work and how long their effects last. The types of insulin include: Rapid-acting Short-acting Intermediate-acting Long-acting Pre-mixed What Type of Insulin Is Best for My Diabetes? Your doctor will work with you to prescribe the type of insulin that's best for you and your diabetes. Making that choice will depend on many things, including: How you respond to insulin. (How long it takes the body to absorb it and how long it remains active varies from person to person.) Lifestyle choices. The type of food you eat, how much alcohol you drink, or how much exercise you get will all affect how your body uses insulin. Your willingness to give yourself multiple injections per day Your age Your goals for managing your blood sugar Afrezza, a rapid-acting inhaled insulin, is FDA-approved for use before meals for both type 1 and type 2 diabetes. The drug peaks in your blood in about 15-20 minutes and it clears your body in 2-3 hours. It must be used along with long-acting insulin in people with type 1 diabetes. The chart below lists the types of injectable insulin with details about onset (the length of time before insulin reaches the bloodstream and begins to lower blood sugar), peak (the time period when it best lowers blood sugar) and duration (how long insulin continues to work). These three things may vary. The final column offers some insight into the "coverage" provided by the different insulin types in relation to mealtime. Type of Insulin & Brand Names Onset Peak Duration Role in Blood Sugar Management Rapid-Acting Lispro (Humalog) 15-30 min. 30-90 min 3-5 hours Rapid-acting insulin covers insulin needs for meals eaten at the same time as the injection. This type of insulin is often used with Continue reading >>

How To Mix Insulin Clear To Cloudy

How To Mix Insulin Clear To Cloudy

Learn how to mix insulin clear to cloudy. Drawing up and mixing insulin is a skill that nurses will utilize on the job. Insulin is administered to patients who have diabetes. These type of patients depend on insulin so their body can use glucose. Therefore, nurses must be familiar with how to mix insulin. The goal of this article is to teach you how to mix insulin. Below are a video demonstration and step-by-step instructions on how to do this. How to Mix Insulin Purpose of mixing insulin: To prevent having to give the patient two separate injections (hence better for the patient). Most commonly ordered insulin that are mixed: NPH (intermediate-acting) and Regular insulin (short-acting). Important Points to Keep in Mind: Never mix Insulin Glargine “Lantus” with any other type of insulin. Administer the dose within 5 to 10 minutes after drawing up because the regular insulin binds to the NPH and this decreases its action. Check the patient’s blood sugar and for signs and symptoms of hypoglycemia to ensure they aren’t hypoglycemic …if patient is hypoglycemic hold the dose and notify md for further orders. Key Concept for Mixing Insulin: Draw up CLEAR TO CLOUDY Remember the mnemonic: RN (Regular to Nph) Why? It prevents contaminating the vial of clear insulin with the cloudy insulin because if contaminated it can affect the action of the insulin. Why does this matter because they will be mixed in the syringe? You have 5 to 10 minutes to give the insulin mixed in the syringe before the action of the insulins are affected Demonstration on Drawing Up Clear to Cloudy Insulin Steps on How to Mix Insulin 1. Check the doctor’s order and that you have the correct medication: Doctor’s order says: “10 units of Humulin R and 12 units of Humulin N subcutaneous before b Continue reading >>

More in insulin