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Insulin Dosing And Outcomes Among Commercially Insured Patients With Type 2 Diabetes In The United States

Abstract The purpose of this study was to examine costs, resource use, adherence, and hypoglycemic events among patients with type 2 diabetes mellitus (T2DM) treated with increasing doses of 100-U/mL (U-100) insulin regimens. Data from Truven’s Health Analytics Commercial Claims and Encounters database from January 1, 2008, through January 31, 2011, were used. Regressions were used to examine the associations among costs, resource use, adherence, and receipt of a hypoglycemic event and index dose of insulin. Specifically, general linear models with a γ-distribution and log link were used to examine costs, whereas logistic and negative binomial regressions were used to examine resource use and hypoglycemic events. All analyses controlled for patient characteristics, preindex comorbidities, general health, use of antidiabetic medications, and visits to an endocrinologist. The study focused on 101,728 individuals with T2DM who received an outpatient prescription for U-100 insulin. In general, costs and resource use are highest among patients treated with the highest dose of insulin (>300 U/d). For example, all-cause and diabetes-related hospitalizations and office visits were highe Continue reading >>

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Popular Questions

  1. J Fiddy

    Basal-bolus insulin calculator

    Calculator for initiating or modifying basal-bolus insulin therapy with correction dosing scales akin to what exists on www.bbit.ca

  2. Admin

    Unfortunately, we're not allowed to add dose calculators, see here:
    http://medcalc.pro/dosegate.html

    I'll leave this in the list though, maybe we'll find a solution in the future.

  3. -> Continue reading
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