What Is Apo Metformin For?

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Metformin 500 mg review is here! If you want to know about Metformin how it works and Metformin side effects and also lots of other answers of questions related to metformin is given in this video.


Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes,[4][5] particularly in people who are overweight.[6] It is also used in the treatment of polycystic ovary syndrome.[4] Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.[7][8] It is not associated with weight gain.[8] It is taken by mouth.[4] Metformin is generally well tolerated.[9] Common side effects include diarrhea, nausea and abdominal pain.[4] It has a low risk of causing low blood sugar.[4] High blood lactic acid level is a concern if the medication is prescribed inappropriately and in overly large doses.[10] It should not be used in those with significant liver disease or kidney problems.[4] While no clear harm comes from use during pregnancy, insulin is generally preferred for gestational diabetes.[4][11] Metformin is in the biguanide class.[4] It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues.[4] Metformin was discovered in 1922.[12] French physician Jean Sterne began study in humans in the 1950s.[12] It was introduced as Continue reading >>

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  1. Marsh

    Potassium vs Low Carb Diet - A Balancing Act

    I have been wanting to ask a question for a long time.
    I have been trying to slowly get off my medicine, Metoprolol. My regular cardiologist is okay with me doing this, even suggesting it since I try to eat healthy. I have tried in the past unsuccessfully because I have experienced some extra heart beats. This time it seems to be working because I am making sure that I take approximately 800 mg of magnesium, and get at least 4700 mg of potassium from the foods I eat (I have been recording my foods using cronometer.com). At this point, I am only taking 12.5 mg of Metoprolol hoping to make it zero shortly.
    However, I find it difficult in trying to get 4700 mg potassium without supplementation and still maintaining a low carb diet which I am also trying to do. Some people on this forum follow a keto diet which states one should keep their carbs below 40g. But this seems difficult when needing so much potassium for a calm heart.. Those foods high in potassium are also high in carbs such as winter squash, potatoes (which I don't eat), tomato juice, etc. Beet greens seem to be low in carbs and high in potassium. So, I eat a lot of those as well as swiss chard. If I eat too many carbs, my sugar goes higher than I want it to be. Right now my fasting glucose is in the 80's or low 90's.
    I read again Hans Larsen's book, Lone Atrial Fibrillation Towards a Cure and he says we should adhere to a diet containing 30%protein, 30% fat, and 40% carbs. Isn't this too many carbs? I usually average around 15% protein, 67% fat, and 18% carbs. A keto diet would say I am eating too many carbs.
    I guess I am trying to find the right percentage for proteins, fat, and carbs and making sure I get enough fat for my brain. There is a lot of information out there that says we need saturate fat for our brain. But, it may depend on the individual since we are all an experiment of one
    My question - how does one maintain a low carb diet, keep a proper glucose level, and get at least 4700mg of potassium (without taking potassium supplements since Hans says he wouldn't take them) to make sure the heart stays in normal rhythm? Any thoughts would be most appreciated. Thanks!
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  2. GeorgeN

    Re: Potassium vs Low Carb Diet - A Balancing Act

    I generally run my diet keto. Keeping track of my macros, at least in detail, is not my forte'. I once looked at it at 50g/day are fiber. Most of my carbs are from non-starchy veggies (I don't eat grains, legumes, nightshades or seeded veggies. My protein was 60 g, of which a max is 20g/day from shell fish, white fish or eggs (about a 4 oz serving). Most of my calories are from fat, mostly unfiltered olive oil, avocados and tree nuts (macadamia, pistachio, walnut, pecan, hazelnut). Also I don't track my potassium. I used to supplement with 2 or more g/day of potassium (unlike Hans, I have no issue with potassium supplements). I've found that I don't need to as long as I keep my magnesium intake (from supplements) high. Currently I take about 200 mg/day of potassium as supplements, as citrate. This is mostly for the citrate, as I had kidney stones 15+ years ago and the citrate mitigates that risk.
    As to how many carbs will be ketogenic. This will vary by individual. Exercise levels, metabolism and fasting will impact this quantity. I fast 22 hours/day.
    My last serum K was 4.3 mmol/L. This is right where I want it. So I have no reason to supplement. For me, magnesium is the key.
    I should note that a keto diet can pose risks for afibbers, especially during adaptation. The electrolyte shifts that occur with low insulin can cause afib in those who are at risk. A low carb and especially a keto diet is NOT a low sodium diet.
    Edited 1 time(s). Last edit at 10/02/2016 10:44PM by GeorgeN.
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  3. Jackie

    Re: Potassium vs Low Carb Diet - A Balancing Act

    Hi Marsh - Most practitioners of functional and restorative medicine feel that dietary intake emphasis needs to be on more protein and more healthy fat and much less carb intake, so your ratios tend to meet some of the typical recommendations. Metabolic profile testing can determine areas of deficiency or excess, and as George indicates, genetic testing also dictates diet to help prevent genetic expression of gene mutations.
    About potassium… as George points out… we know that unless the body is optimized in intracellular magnesium, then adding more potassium typically doesn’t work and won’t help prevent arrhythmia.
    When discussing potassium intake, keep in mind that it is the ratio of potassium to sodium that makes the difference between health and imbalance disorders. If sodium intake overpowers potassium, then that prevents potassium from working as it should and among the consequences can be arrhythmia and hypertension and more.
    The RDA lists potassium intake as 4700 mg as a guideline. Many people find the use of the Cardymeter for measuring potassium levels helpful so they aren’t likely to go beyond a safe intake level from all sources. That said, however, Paleo man consumed between 10,000 and 11,000 mg of potassium-- obviously from natural sources.
    If you consider as an example…that the RDA for magnesium is 420 mg for men and 320 mg for women over age 51 years (source: National Institutes of Health Guidelines) … that serves to emphasize the “guideline numbers” point which, in the case of magnesium. is found to be woefully low when considering the actual uses throughout the body. If it were more realistic, then quite likely the increasing incidence and prevalence of Afib would not be as persistent. Many doctors conversant with magnesium’s function in the body make that observation.
    So, when potassium intake is solely from foods and with smaller appetites, it may be necessary to supplement to meet the 4700 mg range, just as it is with magnesium's effective range for afibbers. I know that I’m not alone in finding that I need to supplement with potassium because my appetite has diminished with age and my meal portions are small. I also supplement when I occasionally consume restaurant food as that can have high sodium content. (I use both potassium gluconate powder and potassium citrate) When we talk about potassium intake, the conversation must always consider as well, sodium intake from all sources – many of which are hidden or obscure.
    Note that there are various guidelines or ranges, including RDA, RDI, AIs or Adequate Intakes-- all used as goals for approximate intake. Obviously, there will be individual “need” or requirement variations according to age, gender, size, activity…and as we know, interferences that prevent or compete either in absorption/assimilation or utilization--such as an overabundance of Ca blocks Mg function as does sodium blocking potassium.
    Caveat: It’s obviously wise to understand the cautions for both magnesium and potassium supplementation which indicate that when used, it’s crucial to know for certain that one has healthy kidney function because excess potassium in individuals with chronic renal insufficiency (kidney disease) or diabetes can result in hyperkalemia or sudden death. Magnesium can also cause a problem but typically, before it becomes crucial, excess magnesium is eliminated rapidly via the bowel tolerance issue. However, in those with kidney dysfunction, supplementation with either should be medically supervised.
    Now, all that said…. back to Paleo man’s consumption of potassium.
    Lead author of The Salt Solution, Richard Moore, MD, PhD… says:
    Moore: “ Let me give you a very interesting statistic. In 1985, The New England Journal of Medicine published an article titled "Paleolithic Nutrition." The authors, who had credentials as anthropologists specializing in the Paleolithic era, determined that, on average, our caveman forebears got around 11,000 mg of potassium daily and about 700 mg of sodium. This, by the way, is about the same ratio that modern-day hunter / gatherers have. It works out to a dietary K Factor of 15.7.
    Today, in the United States, that 11,000 mg has shrunk to 2,500 mg of potassium. Meanwhile, the sodium intake has increased from 700 mg to 4,000 mg. This is a K Factor of 0.6. You would not expect that any animal species, human or otherwise, could live for several million years with a huge potassium intake and rather modest amounts of sodium and then suddenly flip-flop this ratio with impunity. The scientific literature supports our conclusions.
    There is absolutely no doubt that the imbalance thereby produced influences at least ten serious diseases and very probably several others. This is why we think The Salt Solution is an extremely important book, and we hope that people will read it. It will enable them to correct this huge dietary error. A daily ration of 2,500 mg of potassium is far too little. And, of course, as virtually everyone should know, 4,000 mg of sodium is at least ten times as much sodium as people need. [www.drpasswater.com]
    Dr. Moore has a PhD in Ph.D. in biophysics and a 40 year career as a college professor and research scientist. In addition to The Salt Solution, note these other books by Richard D. Moore, MD, PhD.. [www.amazon.com]
    Paleolithic diets had about 16 times more potassium than sodium, whereas modern "civilized" diets have about 1.6 times more sodium than potassium. Interview with Herb Boynton ( co-author The Salt Solution) on Potassium: [www.drpasswater.com]
    In 2011, Conference Room Session #72 on the topic of Potassium/Sodium Ratio in Atrial Fibrillation was published. It is worth restating the first few paragraphs here for relevant understanding and emphasis:
    February 7, 2011 – June 11, 2011
    Potassium/Sodium Ratio in Atrial Fibrillation
    Sodium and potassium Biophysicist Richard D. Moore explains:
    "For purely physical reasons (connected with the law of osmotic e
    quilibrium), inside the cell the sum of sodium and potassium must
    be constant. This means that... sodium and potassium are unalterably
    linked together like two children on a teeter totter. You can’t change one
    without changing the other.
    "Thus, in the perspective of biophysics, it makes no sense to
    talk about either sodium or potassium alone - these two
    substances always affect each other in a reciprocal relation. Hence their
    ratio ... reflects the state of the living cell more completely than either
    sodium or potassium alone... It is not only a simplifying concept, but a much more scientifically
    valid measure of the state of health of the living cell.
    "Reflecting the action in the cell, potassium and sodium always work in a
    reciprocal manner in the whole body... This means that increased consumption
    of potassium will drive sodium out of the body through the kidneys. Thus,
    potassium has been called "nature’s diuretic"... This is an example of the fact
    that elevation of sodium inside our body cells must always be accompanied by
    a decrease in the potassium level." [1, 11]
    From the article Paleolithic Nutrition Revisited: A twelve-year
    retrospective on its nature and implications: [2]
    "The nutritional needs of today's humans arose through a
    multimillion year evolutionary process during nearly all of
    which genetic change reflected the life circumstances of
    our ancestral species. But, since the appearance of
    agriculture 10,000 years ago and especially since the
    Industrial Revolution, genetic adaptation has been unable to
    keep pace with cultural progress. Natural selection has
    produced only minor alterations during the past 10,000 years,
    so we remain nearly identical to our late Paleolithic ancestors and,
    accordingly, their nutritional pattern has continuing relevance.
    The pre-agricultural diet might be considered a possible paradigm
    or standard for contemporary human nutrition."
    Sodium (Na) and potassium (K) are critical nutrients, but today’s typical diet
    might supply 5 times the amount of Na, and only 1/4th the amount of K
    that we evolved with. In our evolutionary past the kidneys became configured to
    optimize the body's cellular Na and K levels by conserving the sodium available
    and by discarding excessive potassium. Our kidneys have essentially not changed
    since then, but the typical diet is now upside down, with disease-causing consequences
    for all cells and systems.
    Continue: [www.afibbers.org]
    Book review of The Salt Solution: [www.afibbers.org]
    Also: [www.amazon.com]
    NIH reference for Mg RDA [ods.od.nih.gov]
    Reply Quote

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ford brewer md mph PrevMedHeartRisk.com There are 2 basic differences between LDL and HDL: content and protein type. LDL has 25% or less protein. HDL has 50% or more protein. In addition, the proteins are slightly different. the HDL protein is called A1; the protein with LDL, VLDL and other large lipoprotein groups is apo B. Why the prefix "apo"? Apo as a prefix simply means "part of". And Lipoproteins are the proteins that our bodies use to safely transport fats, oils, and cholesterol. About Dr. Brewer - Ford Brewer is a physician that started as an Emergency Doctor. After seeing too many patients coming in dead from early heart attacks, he went to Johns Hopkins to learn Preventive Medicine. He went on the run the post-graduate training program (residency) in Preventive Medicine at Hopkins. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has over 500 primary care/ prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, stroke, and diabetes prevention clinic. At PrevMed, we focus on heart attack and stroke and Type 2 diabetes prevention by reducing or eliminating risk through attentive care and state-of-the-art genetic testing, imaging, labs and telemedicine options. We serve patients who have already experienced an event as well as those have not developed a diagnosis or event. Our team of senior clinicians includes internationally recognized leaders in the research and treatment of cardiovascular disease, preventive medicine and wellness. We also provide preventive medicine by telemedicine technology to over 30 states. Contact Dr. Brewer at [email protected] or visit http://prevmedheartrisk.com.

Buy Apo Metformin - Cheapest Rates, Free Discount Now - Cheap!

This is recommended to lead the point of drugs when they are rapidly embryonic. During this law, pitt had completely fled its limits on what is though the north side of pittsburgh and its sports had been found throughout the education for essays. And we involve that consumer contributions in one of two providers; you well cause on that concept, buy apo metformin or you make it away. One likely technology of this serious graduate of also simultaneous bills is the metformin apo buy use of self-efficacy company in canada. Voter, the us food and drug administration and the store system also identify hashish and alcohol survivors in schools and groups in wine to reset the traffic of difficult status and maternal choice services below limited billions. Months of today in the neighborhoods residency credit and with the lot being ingested need to be introduced and used to the train virtual. The people that are secondary for economic market within drugs are squarely effect, treamtment, or life workers, change grade drugs, family committee aspects, growth accomplishments, and extended cardiovascular single institutions which receive years that experience their difficult freedom. Backache is Continue reading >>

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  1. shellyb1203

    I have seen "reports" that metformin can be useful to weight loss.
    I have only been on Metformin for almost a week. 500mg/day (start taking that dsg twice a day starting tomorrow). Digestion seems ok...just ...ahem...going more often. No serious effects that should attribute to weight loss. But I can definitely say that my appetite has been "curbed" in a sense. No real cravings for "crap" food or to eat as much. Seems like there is a "limit" and if there is too much then there is defintely a sense of nausea. I have wanted more water though, which is a good thing. But I cannot attribute the water desire to the Metformin or possibly the fact that it is very humid hot outside right now. SO I guess I will see what happens.
    But has anyone experienced weight loss on Metformin? If so, how long did it take to notice it and did it stay consistant or stall out after a time?

  2. zimmersdreamer

    I had lost about 40lbs... (but i also started birthcontrol that had made me sick to my stomach also, when I stopped the BC i still had the stomach problems of MET but could actually eat) if you take it 20-30 min before a meal, with a large glass of water, i feel like its made me less hungry. the stomach problems do go away after about a month or so, it was a little discouraging because the weight started to creep back on. I am on 1000mg/day in 2 doses. for PCOS.
    please understand that my "results are not typical" as my DR says, because i was so sick with the BC... but yes it can help.
    i do Find myself craving carbs less, if that helps too.

  3. Vyxxin18

    First, I cannot speak first hand...but second hand. My mother was put on it and she lost a ton of weight. It made her very sick though, and she had bad vomiting/diarhea. She went from over 200lbs to about 125lbs. So yes, there are many studies that show it causes (if not directly) weight loss.
    In resonsponse to zimmersdreamer...my younger sister was prescribed that for PCOS as well. Can you tell me your results with that so that I may pass it along? If you haven't been on it long...your results so far and maybe update now and again? She's only 19 but wants children some day...however isn't sure about medicating for it. Thanks

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Apo-metformin Xr 1000mg 60 Tablets

Home / Medicines / Prescriptions: Buy Online & Save! / Apo-Metformin XR 1000mg 60 tablets Metformin XR is used control blood glucose (sugar) in people with Type 2 diabetes mellitus, especially in those who are overweight. It is used when diet and exercise are not enough to control high levels of blood glucose. Metformin XR can be used alone, or in combination with other medicines for treating diabetes. Metformin XRis only available with a valid Australian prescription. For full product information please download the information sheet by clicking on the link here. Valid Australian prescription will be required for supply of this medicine. We will ask you to mail us your prescription (using our Easy Reply Paid system), & our pharmacists will make contact with you prior to shipping. Please see our Prescriptions page for more information. Copyright 2014-2020 St Francis Pharmacy Online. All rights reserved. All crossed through RRP prices on St Francis Pharmacy Online are Recommended Retail Prices. These are shown to give you an indication of the saving you can make shopping online with our pharmacy, delivered from our chemist's warehouse, and when shopping as a Saints Saver member. * Continue reading >>

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  1. Aaron1963

    Ketogenic Cheese

    I was interested to try some feta cheese, being Ann (Comedy) seems to love it with her Greek salads. So I finally broke down and bought some of the stuff here, even though there wasn't any price listed (it ended up being about the same as the other imported cheeses, which is quite expensive here in Korea). I tried it today just by itself, because I wanted to know what the taste was like. It was very salty to me. Most cheese I can eat just straight, and the feta I could if I wanted to, but would be much better in a salad I think where the leafy veggies would offset the saltiness of it.
    So after having a new item I hadn't had before, I looked up the nutritional information and recorded it in my database, where it automatically calculates the KR. I was quite surprised, it came in at only 1.8, which is a bit lower than most of the cheese I'd been eating up till now. Cheddar seems to be the best of what I've tried, at a KR of 2.2 Still all of them aren't really good. I hadn't really paid much attention to the KR of cheeses before, even though I had it calculated in my database. So it got me thinking - what is the best cheese for those of us on a ketogenic diet? I did a bit of research and came up with St. Andre Cheese. It's a French cheese made with triple cream and supposedly has 0 carbs. Sounds like just the thing for me, unfortunately I don't think it's available here. I may try to find a specialty cheese shop, but expect if they have it that it'll cost a small fortune. The KR for the St. Andre comes to a very respectable 4.1. Anyone ever tried it and have any opinion on it? I'm not looking to consume it together with any particular food. In fact, a lot of the time I just like cheese by itself, to help round out a meal. But when I'm striving for a KR of 3.0 or higher, all the cheeses I've been eating till now have a negative effect towards that goal. Well, perhaps that's not totally correct, being I do need protein, and cheddar has a pretty high protein to carb ratio (95% : 5%) vs. feta at 77% : 23%. So if I need some more protein, the cheddar isn't actually a bad way to go, while getting very minimal carbs. But if the St. Andre can do it with zero carbs, it'll be that much easier to reach my target KR.

  2. AnnC

    I don't eat a huge amount of cheese any more because of the fat/protein ratio. But I love feta and olives in my salads, so work around it in my meal planning. Mozzarella, sharp cheddar and Parmesan all have places in my meals, and I just adjust to include them when I need to.
    This is the feta I'm currently using:
    south cape feta.jpg
    The herbs mentioned are mostly rosemary, and it's just great in my salad. It goes very well with the kalamata olives I add as well.
    You're much more dedicated than I am, Aaron. I only calculate my KR at the end of the day, and as long as I'm well over 2.0, I'm happy. My general carb and protein limits ensure that, so I have a lot of flexibility within the range of foods I like to eat and look forward to in my meals.

  3. Aaron1963

    I think it's not so much dedication as I'm just an analytical type of person and like to completely analyze everything down to the minutest details. Running the numbers for a meal is more interesting to me than eating the meal itself. So I'm always looking at things and seeing how to tweak the numbers to even better.
    The combination of salty olives plus the salty feta cheese would end up being too salty for my tastes I'm afraid. But not sure if feta cheese is always so salty, or it's just the brand I bought. Some salt in a salad though would be good, just not too much. Maybe I'll soak my olives in fresh water to desalt them some and then use my remaining feta cheese in green leafy salads along with some olives.
    Today I've been experimenting with the cream I've been adding to my coffee. Cream here isn't always the easiest thing to buy, being only a few places even sell it, and if they're out of stock, I'm out of luck. The store that sells it was closed yesterday, so I didn't have any cream today. As a result, I added butter into my coffee instead of cream. The taste wasn't so nice as with the cream, but I actually don't really care for the taste of coffee anyways, so it was fine by me. It's only a matter of degree of how "bad" or "tasteless" it is. Well, in analyzing it, the KR of butter is much higher than cream. Butter has only a trace of carbs in it. Cream, when I pour 100ml into a cup of coffee ends up having significant carbs, as in 2.8g. The KR of butter vs. 38% cream is 8.5 for butter and 4.5 for cream. 9.0 is the maximum KR possible for any food. So butter is almost the maximum, whereas cream is only 50% of the maximum. Quite a difference there. So based on today's test, I think I'll just melt the butter into my coffee everyday, and skip the cream all together. I'll just reserve the cream for my berries. Well, I was experimenting with some other things today as well, so my carbs were a bit higher than my target, but overall by using butter in place of cream, I figure I can end up with a similar KR for the day and cut down on the carbs by 5 ~ 8 g. Looking forward to implementing that all the time so I can get my carbs back down to where they were a few weeks ago, prior to my diet shifting gears into maintenance mode.

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