Metformin Hcl Er 500 Mg Vs Metformin Hcl 500 Mg

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Metformin Extended Release Versus Metformin Immediate Release In Subjects With Type 2 Diabetes (consent)

This is a Phase 4, prospective, open label, randomized, parallel controlled multicenter trial in which metformin extended release (XR) will be compared with metformin immediate release (IR) for the gastrointestinal tolerability and efficacy in the newly diagnosed subjects with Type 2 diabetes who have glycosylated hemoglobin (HbA1c) value between 7.0 to 10.0 percent (%). Study Type : Interventional (Clinical Trial) Actual Enrollment : 532 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: CONSENT - Comparison of metfOrmin XR to IR as moNotherapy in the Newly diagnoSed Type 2 diabEtes Patients for the gastroiNtestinal Tolerability and Efficacy: a Randomized, Parallel Control, Open-label and Multicenter Study Study Start Date : December 2014 Primary Completion Date : November 2015 Study Completion Date : April 2016 Arm Intervention/treatment Active Comparator: Metformin IR Drug: Metformin IR Subjects will receive Metformin Immediate Release (IR) tablets, orally once daily at a dose of 500 milligram (mg) for 1 week, and then dose will increase with increments of 500 mg every week in first 2 Continue reading >>

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Popular Questions

  1. Hotairjones

    Metformin vs Metformin ER

    Is there much difference in the GI side effects of the ER form of metformin??? I'm having difficulty with the diarrhea problems taking the 500mg regular form twice a day. Will there be less problems with ER?
    Thanks for info.

  2. ZannaSu

    I can't refer you to specific studies or anything, but when my endocrinologist put me back on metformin (along with my insulins), he specifically mentioned that he was going to use the ER version as it has fewer "stomach issues" than the older version. My issues were nausea and vomiting from the regular, but I have not had any of that , not even mild discomfort with the ER. I think it would be worth trying. Every body is different. What works for me might not work for you. Maybe your doctor can offer you a sample so you can try it for a week or so and see if there is any difference. That way you wouldn't have to start a second prescription if there was no difference.

  3. cavie2

    I must have a very strong constitution, I take Metformin 3 X 850 and have never had any problems with it

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