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Metformin Er 500mg 24hr Tabs

Metformin Hcl Er

Metformin Hcl Er

Uses Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. How to use Metformin HCL ER Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily with the evening meal. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects (such as upset stomach), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regula Continue reading >>

Metformin, Oral Tablet

Metformin, Oral Tablet

Metformin oral tablet is available as both a generic and brand-name drug. Brand names: Glucophage, Glucophage XR, Fortamet, and Glumetza. Metformin is also available as an oral solution but only in the brand-name drug Riomet. Metformin is used to treat high blood sugar levels caused by type 2 diabetes. FDA warning: Lactic acidosis warning This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects. Lactic acidosis is a rare but serious side effect of this drug. In this condition, lactic acid builds up in your blood. This is a medical emergency that requires treatment in the hospital. Lactic acidosis is fatal in about half of people who develop it. You should stop taking this drug and call your doctor right away or go to the emergency room if you have signs of lactic acidosis. Symptoms include tiredness, weakness, unusual muscle pain, trouble breathing, unusual sleepiness, stomach pains, nausea (or vomiting), dizziness (or lightheadedness), and slow or irregular heart rate. Alcohol use warning: You shouldn’t drink alcohol while taking this drug. Alcohol can affect your blood sugar levels unpredictably and increase your risk of lactic acidosis. Kidney problems warning: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug. Liver problems warning: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems. Metformin oral tablet is a prescription drug that’s available as the brand name drugs Glucophage, Glucophage XR, Fortamet, and Glumetza. Glucophage is an immediate-release tablet. All of the other brands are extended-r Continue reading >>

Metformin Hcl Er

Metformin Hcl Er

Metformin Hydrochloride Extended-Release Tablets, USP 500mg Keep this and all medication out of the reach of children. Dispense in a light-resistant container. Store at 20 to 25C (68 to 77F) [See USP Controlled Room Temperature]. Does not contain ingredients derived from animal source. No. Product verified not to contain any gluten. Colloidal silicon dioxide, hypromellose, magnesium stearate and microcrystalline cellulose. Metformin hydrochloride extended-release tablets, USP are indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes. Continue reading >>

Proper Use

Proper Use

Drug information provided by: Micromedex This medicine usually comes with a patient information insert. Read the information carefully and make sure you understand it before taking this medicine. If you have any questions, ask your doctor. Carefully follow the special meal plan your doctor gave you. This is a very important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment. Swallow the extended-release tablet whole with a full glass of water. Do not crush, break, or chew it. While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about. Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. You may notice improvement in your blood glucose control in 1 to 2 weeks, but the full effect of blood glucose control may take up to 2 to 3 months. Ask your doctor if you have any questions about this. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the Continue reading >>

Diabetes Drugs: Metformin

Diabetes Drugs: Metformin

Editor’s Note: This is the second post in our miniseries about diabetes drugs. Tune in on August 21 for the next installment. Metformin (brand names Glucophage, Glucophage XR, Riomet, Fortamet, Glumetza) is a member of a class of medicines known as biguanides. This type of medicine was first introduced into clinical practice in the 1950’s with a drug called phenformin. Unfortunately, phenformin was found to be associated with lactic acidosis, a serious and often fatal condition, and was removed from the U.S. market in 1977. This situation most likely slowed the approval of metformin, which was not used in the U.S. until 1995. (By comparison, metformin has been used in Europe since the 1960’s.) The U.S. Food and Drug Administration (FDA) required large safety studies of metformin, the results of which demonstrated that the development of lactic acidosis as a result of metformin therapy is very rare. (A finding that has been confirmed in many other clinical trials to date.) Of note, the FDA officer involved in removing phenformin from the market recently wrote an article highlighting the safety of metformin. Metformin works primarily by decreasing the amount of glucose made by the liver. It does this by activating a protein known as AMP-activated protein kinase, or AMPK. This protein acts much like an “energy sensor,” setting off cellular activities that result in glucose storage, enhanced entry of glucose into cells, and decreased creation of fatty acids and cholesterol. A secondary effect of the enhanced entry of glucose into cells is improved glucose uptake and increased storage of glycogen (a form of glucose) by the muscles. Additionally, the decrease in fatty acid levels brought about by metformin may indirectly improve insulin resistance and beta cell func Continue reading >>

Metformin Weight Loss – Does It Work?

Metformin Weight Loss – Does It Work?

Metformin weight loss claims are something that are often talked about by health professionals to be one of the benefits of commencing metformin therapy, but are they true? At myheart.net we’ve helped millions of people through our articles and answers. Now our authors are keeping readers up to date with cutting edge heart disease information through twitter. Follow Dr Ahmed on Twitter @MustafaAhmedMD Metformin is possibly one of the most important treatments in Type II Diabetes, so the question of metformin weight loss is of the utmost importance, as if true it could provide a means to lose weight as well as control high sugar levels found in diabetes. What is Metformin? Metformin is an oral hypoglycemic medication – meaning it reduces levels of sugar, or more specifically glucose in the blood. It is so effective that the American Diabetes Association says that unless there is a strong reason not to, metformin should be commenced at the onset of Type II Diabetes. Metformin comes in tablet form and the dose is gradually increased until the maximum dose required is achieved. How Does Metformin Work & Why Would it Cause Weight Loss? Metformin works by three major mechanisms – each of which could explain the “metformin weight loss” claims. These are: Decrease sugar production by the liver – the liver can actually make sugars from other substances, but metformin inhibits an enzyme in the pathway resulting in less sugar being released into the blood. Increase in the amount of sugar utilization in the muscles and the liver – Given that the muscles are a major “sink” for excess sugar, by driving sugar into them metformin is able to reduce the amount of sugar in the blood. Preventing the breakdown of fats (lipolysis) – this in turn reduces the amount of fatt Continue reading >>

Metformin Extended-release Tablets

Metformin Extended-release Tablets

Generic Name: Metformin Extended-Release Tablets (met FOR min) Brand Name: Fortamet, Glucophage XR Warning Rarely, metformin may cause an acid health problem in the blood (lactic acidosis). The risk of lactic acidosis is higher in people with kidney problems and in people who take certain other drugs like topiramate. The risk is also higher in people with liver problems or heart failure, in older people (65 or older), or with alcohol use. If lactic acidosis happens, it can lead to other health problems and can be deadly. Lab tests to check the kidneys may be done while taking this medicine (metformin extended-release tablets). Talk with the doctor. Call your doctor right away if you have signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast or slow heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps. Do not take this medicine if you have a very bad infection, low oxygen, or a lot of fluid loss (dehydration). Talk with your doctor before you drink alcohol. If you are having an exam or test with contrast or have had one within the past 48 hours, talk with your doctor. Tell all of your health care providers that you take this medicine (metformin extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists. Uses of Metformin Extended-Release Tablets: It is used to lower blood sugar in patients with high blood sugar (diabetes). What do I need to tell my doctor BEFORE I take Metformin Extended-Release Tablets? If you have an allergy to metformin or any other part of this medicine. If you are allergic to any drugs like this one, any other drugs, foods, o Continue reading >>

Glucophage

Glucophage

GLUCOPHAGE® (metformin hydrochloride) Tablets GLUCOPHAGE® XR (metformin hydrochloride) Extended-Release Tablets DESCRIPTION GLUCOPHAGE® (metformin hydrochloride) Tablets and GLUCOPHAGE® XR (metformin hydrochloride) Extended-Release Tablets are oral antihyperglycemic drugs used in the management of type 2 diabetes. Metformin hydrochloride (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. The structural formula is as shown: Metformin hydrochloride is a white to off-white crystalline compound with a molecular formula of C4H11N5 HCl and a molecular weight of 165.63. Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pK of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. GLUCOPHAGE tablets contain 500 mg, 850 mg, or 1000 mg of metformin hydrochloride. Each tablet contains the inactive ingredients povidone and magnesium stearate. In addition, the coating for the 500 mg and 850 mg tablets contains hypromellose and the coating for the 1000 mg tablet contains hypromellose and polyethylene glycol. GLUCOPHAGE XR contains 500 mg or 750 mg of metformin hydrochloride as the active ingredient. GLUCOPHAGE XR 500 mg tablets contain the inactive ingredients sodium carboxymethyl cellulose, hypromellose, microcrystalline cellulose, and magnesium stearate. GLUCOPHAGE XR 750 mg tablets contain the inactive ingredients sodium carboxymethyl cellulose, hypromellose, and magnesium stearate. System Components And Performance GLUCOPHAGE XR comprises a dual hydrophilic polymer matrix system. Metformin hydrochloride is combined with a drug release controlling polymer to form an “inne Continue reading >>

Metformin Er 500 Mg - Topics - Medschat

Metformin Er 500 Mg - Topics - Medschat

long whitenpill with #571 on it ## The pill in description is confirmed to be Metformin hydrochloride ER (500 mg); which is an oral anti-diabetic drug in the biguanide class. NOTE: The full description is 571 with a triangular symbol next to it and on the other side there is the number 500. You can view a detailed description of the drug, by clicking on the link below... If you have any more questions or comments to add, please post back so I can further assist you. ... Anyone that has questions about their medication, should always consult with their Pharmacist they are a wealth of information. ## I have been taking metformin hcl 500 mg tab. My prescription looks different. The round white tablet has I45 on one side. Is this metformin hci 500? ## I'm taking Metformin Hcl Er 500mg tablet, and my husband i taking Metformin HCL 500mg tablet , is ther any different in the medication ## They are a wealth of information, or it may be better to say that they should be, because not all of them make themselves available to help customers with questions, especially in some of the larger chain stores that have a lot of customers. Enid, the ER designates yours as being a time released formulation and since there's no ER, SR, XR, CR or etc. listed with his... ... Just given this pill from my old metformin with 7267 on back been having severe diarhea and wondering if anyone else reporting or something with pill change ## Hello, Karhy! How are you? There can be slight differences between generic mediations, according to the Hatch-Waxman Act of 1984. So, this new one might have a little more of the active ingredient than the prior one that you were taking and thus, causing you more side effects. Diarrhea is a typical side effect of this medication, as listed by the FDA, you may also Continue reading >>

Metformin Er - Am/pm Dosage?

Metformin Er - Am/pm Dosage?

Am currently taking Metformin HCL ER, 2 - 500mg tabs daily, at about 6pm, with dinner. In the two months since my surgery my fasting blood glucose level has gone down; in May it ranged from 83-109, mostly in the 90's. However, probably because of overeating in the afternoon, I have gained about 10 lbs. So I am wondering if I should split the Met dose between breakfast and dinner, or take it all in the morning, with my other pills (mostly supplements). Perhaps it would be more effective peaking in the afternoon, when I am eating the most, rather than late night/early morning, as it is now. I don't want to risk morning hypos, true or false - but do want to lose that weight, planning to cut down the Met when I reach a certain goal. D.D. Family Getting much harder to control Met builds in the body and works on the liver, you can try splitting it that might help. Met is not suppose to cause a hypo right now your readings look very good you posted, best wishes to you it never did that for me. I also take two Metformin ER tablets per day (500 mg) and I take one with breakfast and one at bedtime. It worked out to be the easiest times of day for me to remember. Also, I'm sure you know that the ER tablets should not be broken. Thanks - will try taking one in the evening and one in the morning, and see how that goes... I take my kombiglyze xr 2000mg with my evening meal. TUJUEO metformin xr Humalog soon to be novolog I take the regular metformin. My doctor says it shouldn't matter when I take it. But I find it does. I find I get an immediate effect within a few hours as well as an accumulated effect. I take my metformin 3 x a day, before bed, around 5 am and around 9 am. Those are the times my liver seems more active and the metformin seems to calm it down. 115 pounds, Breast Can Continue reading >>

Information On Metformin Hcl Er 500 Mg For Weight Loss

Information On Metformin Hcl Er 500 Mg For Weight Loss

If you have high blood glucose levels, you may take metformin hydrochloride, an oral anti-hyperglycemic medication that lowers blood sugar. Metformin may also help you lose weight in some cases by decreasing your appetite. Clinical studies have not proven that metformin helps you lose weight if you don't have Type 2 diabetes or other metabolic disorders that cause insulin resistance. It may help prevent weight gain or cause modest weight loss if you're taking antipsychotic drugs that cause weight gain. Metformin comes in several doses, including a 500-milligram extended release form, which you may find easier to take. Video of the Day Metformin might help you lose weight if you have metabolic syndrome or polycystic ovary disease, both associated with insulin resistance. The pancreas releases insulin in response to glucose in your bloodstream. Insulin helps cells remove glucose from the bloodstream. When you eat large amounts of high-carb foods, the pancreas may overproduce insulin to keep up. Eventually, your cells stop responding to the insulin and your blood glucose levels rise. Because your cells feel starved for energy, you feel hungry all the time and may crave carbohydrates. Metformin helps cells respond better to insulin, so you don't feel as hungry. Insulin can also cause your liver to convert extra calories to fat. Metformin decreases the amount of glucose your liver produces, and also decreases the amount of glucose absorbed in your intestines. Decreased amounts of glucose in your bloodstream results in less glucose absorbed by your cells. When you absorb less glucose, you lose weight. An Indian study published in the March 2011 "British Journal of Clinical Pharmacology" reported that metformin increased weight loss in people taking olanzapine, an antipsychoti Continue reading >>

Metformin Hydrochloride: Oral Tablet, Extended Release (500mg)

Metformin Hydrochloride: Oral Tablet, Extended Release (500mg)

What is this Medicine? METFORMIN (met FOR min) is used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise. This medicine can be used alone or with other medicines for diabetes. Generic 94.28%Brand 5.72% *Brand contains same active ingredient but may not represent FDA-approved generic equivalent 750mg1000mg500mg Ingredients Close All Sections Reported Side Effects for Metformin Hydrochloride 500mg Extended-Release Tablet Close Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine. Close All Interactions Close If you use tobacco or are trying to quit tobacco use, you may need to monitor your blood sugar more frequently. Nicotine, a component of tobacco, can increase the blood sugar. Also, if you are trying to quit smoking, as your body adjusts to not smoking, your blood sugar levels may change; the actions of Antidiabetic Agents (medicines used to treat diabetes) may be increased and this could lead to low blood sugar. Know the symptoms of low or high blood sugar and report them if they occur. Monitor your blood sugar regularly. Close Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester. Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adver Continue reading >>

Metformin Extended Release Tablets

Metformin Extended Release Tablets

Generic Name: metformin hydrochloride Dosage Form: tablet, extended release Metformin Extended Release Tablets Description Metformin hydrochloride extended release tablets USP are an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. The structural formula is as shown: Metformin hydrochloride is a white to off-white crystalline compound with a molecular formula of C4H11N5· HCl and a molecular weight of 165.63. Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. Metformin hydrochloride extended release tablets USP contain 500 mg of metformin hydrochloride USP as the active ingredient. Metformin hydrochloride extended release tablets USP 500 mg contain the inactive ingredients sodium carboxymethyl cellulose, hypromellose and magnesium stearate. Metformin hydrochloride extended release tablets USP 500 mg meets USP dissolution Test 3. System Components and Performance- Metformin hydrochloride extended release tablets USP comprises a swellable matrix system. In the aqueous gastrointestinal (GI) environment, the dosage form swells remarkably thereby increasing in size and geometry from where drug is released slowly by a process of diffusion through the gel matrix that is essentially independent of pH. The hydrated polymer system is not rigid and is expected to be broken up by normal peristalsis in the GI tract. The biologically inert components of the tablet may occasionally remain intact during GI transit and will be Continue reading >>

Metformin Er 500mg

Metformin Er 500mg

About this medication Metformin ER is the name of the medication. It comes in the form of a tablet, and should be taken by mouth. It belongs to a class of medications called Biguanide. Why is this medication prescribed This medication is used to treat type-2 diabetes and pre-diabetes conditions. Normally, when you eat food, the body breaks down all of the sugars and starches into a sugar called glucose. This is the basic fuel for the cells in the body. The body needs Insulin to be able to use this sugar for energy. Insulin takes the sugar from the blood into the cells. In type 2 diabetes, either the body does not produce enough insulin or the cells ignore the insulin. This causes glucose to build up in the blood instead of going into cells. It can lead to serious diabetes complications. How does it work Metformin belongs to a group of medications called Biguanides. They work by decreasing the amount of sugar produced by the liver and increasing the amount of sugar absorbed by muscle cells. As a result you get more sugar in the cells and less is in the blood. How to use it This medication comes as a tablet. You should put it in your mouth and swallow it with a glass of water. Do not chew, break or crush it. Swallow it whole. What to do if you are pregnant Tell your physician if you become pregnant. There are not enough studies about this medication in pregnant women. Use the medication during pregnancy only if clearly needed. Continue reading >>

Metformin Vs Metformin (mod Vs Osm): What’s The Difference?

Metformin Vs Metformin (mod Vs Osm): What’s The Difference?

Metformin and extended release metformin are used in type 2 diabetes to improve glycemic control in combination with diet and exercise. What are the advantages of extended release metformin? The extended release tablets are taken ONCE DAILY due to their slow release of the medication throughout the day. Extended release tablets are also easier on the stomach which is important for compliance when first starting a new medication. Fortamet and Glumetza are both extended release metformin options, but because the way they release metformin over time is different, they aren’t equivalent to each other. Glumetza is the MOD metformin product. So what does MOD stand for? MOD stands for modified release. Glumetza utilizes advanced polymer delivery technology known as AcuForm® (for the 500 mg tablet) and Smartcoat® (for the 1000 mg tablet). It delivers the metformin to the site of absorption, the duodenum, over a time span of 8 – 9 hours. The tablet then remains in the stomach for an extended period until all of the active drug is released. Does Glumetza have a generic? No. Glumetza does not currently have a substitutable generic equivalent. What is the MAX dose and available strengths of Glumetza? Glumetza comes in 500 mg and 1000 mg extended release tablets, with a max dose of 2000 mg per day. Fortamet is the OSM metformin product. So what does OSM stand for? OSM stands for osmotic release. Fortamet (and its generic equivalents) use single-composition osmotic technology. When you swallow the tablet, water is taken up through the membrane of the pill, which in turn dissolves the drug in the core so it can exit through the laser drilled ports in the membrane. The rate of drug delivery is constant, and will continue as long as there is undissolved drug present in the core ta Continue reading >>

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