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Metformin Doses For Weight Loss

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Metformin Dosage

Metformin Dosage There have been no human studies to identify the optimal dose of metformin that is needed to duplicate the beneficial gene expression effects that are described in the June 2003 issue of Life Extension magazine. For people who want to derive the many proven health benefits of metformin, it might be prudent to follow the dosage schedule used by Type II diabetics. According to the Physician's Desk Reference, the starting dose should be 500 mg of metformin twice a day. (An alternative option is 850 mg of metformin once a day). After one week, increase the dose of metformin to 1000 mg as the first dose of the day and 500 mg as the second dose. After another week, increase to 1000 mg of metformin two times a day. The maximum safe dose described in the Physician's Desk Reference is 2550 mg a day (which should be taken as 850 mg three times a day). According to the Physician's Desk Reference, clinically significant responses in Type II diabetics are not seen at doses below 1500 mg a day of metformin. Anti-aging doctors, on the other hand, have recommended doses as low as 500 mg twice a day to healthy non-diabetics who are seeking to obtain metformin's other proven benefit Continue reading >>

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Popular Questions

  1. doirinne

    How long does it take METFORMIN to help me lose weight?

    I have been diagnosed with insulin resistance Nov 2011. Taking METFORMIN, HCL ER 2000mg (since 11/4/11 worked my way up to full dose). Been on full dose for 2.5 weeks now. No weight loss. I am keeping total daily carbs under 45grams per day. Total calories < 1400. PROTEIN = 60-80GRAMS PER DAY. Diet controlled w/dietician every 6 weeks. I work out 5x per week, 45 mins each time = 50/50 cardio/strength training. Drink 8 glasses of water per day. I am very frustrated. How long does full dose of MET 2000mg take to lose any weight? My endo says he feels I can lose 10 lbs by the follow up appt 2/3/12. I haven't lose one ounce yet. PLEASE HELP. DEE
    Added 15 Dec 2011:
    ps I just read somewhere that I should be taking my metformin with full glass of water. I have not been doing that. Just enough water to get the pills down. Also once or twice a week I will have a glass of sugar free lemonade w/ 1.5 oz of flavored vodka (zero sugar, BUT 6-8 total carbs). Could this interfere w/metformins' effect to help the insulin resistance??????
    Added 15 Dec 2011:
    pps the carbs I consume are 99% from vegetables, either green leafy or steamed/frozen

  2. Delila

    Hi, as you probably know, metformin aids weight loss by reducing your natural instinct of hunger, so you eat less. So it is really down to you to loose the weight by eating healthily which it sounds that you are. To be honest i would have expected you to have lost some weight already... there are foods which can hinder you weight loss, such as foods that increase your blood sugar levels, so you need to be aware of these. I am going to add a link to a website that lists the things you should/should not be doing whilst taking the metformin, including dietary suggestions. I hope you see some results soon.

  3. MO mouawim

    Hi, i am healthy and completely well-balanced with no health problem. i take contraceptive pills. would like to loose around 5KG. Can i take glucofage to help me in the process? thank you

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