Potential Causes Of Weight Gain In Type 1 Diabetes Mellitus.
Abstract AIM: To investigate the potential causes of weight gain with insulin therapy and improved diabetic control in type 1 diabetes mellitus. METHODS: This was an open-label prospective study of insulin therapy of 6 months duration in an academic medical centre. Twenty-one subjects with type 1 diabetes were enrolled. The goal was to achieve an haemoglobin A1c (HbA1c) in the range of individuals without diabetes (<5.6%). At baseline, 3 and 6 months, weight, resting energy expenditure, appetite assessment, food intake, activity level, HbA1c and 24-h glycosuria and urea nitrogen were measured. Plasma leptin, ghrelin and adiponectin levels and body fat were measured at baseline and 6 months. RESULTS: At baseline, average weight was 73.7 +/- 17.4 kg and HbA1c was 10.0 +/- 2.2%. Weight increased by 2.15 kg (2.69% of baseline) by 6 months whereas the HbA1c dropped by 1.71% (16.3%) to 7.9%. Energy intake differences between 3 and 6 months had a negative correlation with weight gain, but the changes in glycosuria, appetite scores and the frequency of hypoglycaemia did not correlate with weight gain. Glycaemic control did not correlate with weight change but tended to correlate with fat mass increase (p = 0.064; r = -0.51). An increase in the activity levels between 3 and 6 months correlated with decreasing fat mass (p = 0.037; r = -0.74). The changes in the appetite scores had a negative correlation with fat mass gain (p = 0.035; r = -0.61). The changes in lean body mass correlated with protein and total energy intake (p = 0.007, r = 0.85 and p = 0.003, r = 0.73 respectively). The changes in leptin levels correlated with weight gain. CONCLUSIONS: The lipogenic effect of insulin with subsequent increase in fat mass may be the primary cause of this weight gain that can be atten Continue reading >>
Lose Weight With Type 1 Diabetes
WRITTEN BY: Cliff Scherb Editor’s Note: Cliff Scherb, Founder of Glucose Advisors and TriStar Athletes LLC, is a nutrition and fitness expert. He consults through virtually teaching his decision support system – Engine1 the app and its methodologies to aspiring T1 individuals and athletes. Cliff also creates custom training programs and insulin plans for endurance athletes, using Training Stress Modeling and real-time coaching. To inquire about coaching openings, FB LIVE sessions, and general questions please email [email protected] Losing weight can be difficult — add Type 1 diabetes to the mix with its daily management demands — and it’s even more of a challenge. I know, because I’ve been a Type 1 diabetic for 29 years and I’m also an endurance athlete. The internet is saturated in advice on how to lose weight with or without Type 1, so it’s hard to know what is worth while and what will just waste your time — or worse, can negatively impact your health. I’m not going to declare all out war on carbohydrates, or tell you can or can’t drink your calories in the form of olive oil, or feast and fast with cayenne peppers and maple syrup. No, the real distilled learning from my years of consulting and data analysis shows that a balanced, low-insulin diet with nutrient timing and activity is the best way to lose weight with Type 1 diabetes. It also helps you maintain brain and body function as well as energy levels. If you are reading this you’ve probably already given this some thought and know why it’s important to lose weight and/or lean out, but I maintain it’s all about performance! Performing means living a longer or healthier life or if you’re an athlete, it can also translate to beating out your competition. Things that Impact w Continue reading >>
Why Does Diabetes Cause Weight Loss In Some People And Weight Gain In Some Others?
To understand dynamics of body weight first we have to understand Energy balance equation which states Calorie intake - calorie lost = Weight So if, Calorie intake > calorie lost = Weight Gain Calorie intake < calorie lost = Weight Loss Calorie intake = calorie lost = Weight is maintained Let's try to understand it in patients with diabetes Scenarios causing weight gain in Diabetes 1. In patients with type 2 Diabetes some may have predominantly insulin resistance ( cells are not as much sensitive to action of insulin as they should be ) This makes their pancreas to secrete excess insulin in an attempt to overcome this resistance . Excessive insulin coupled with high calorie intake causes weight gain 2. A patient of Type 1 Diabetes or type 2 Diabetes who has good control of glucose but consumes excess calories than he needs is bound to gain weight . A good number of patients resort to defensive eating for the fear of hypoglycemia and this also causes weight gain Scenarios causing weight loss in Diabetes 1. Any patient with uncontrolled diabetes will usually have weight loss . This is due to the fact that cells of our body are deprived of glucose as a source of energy and therefore body resorts to using fat and protein as alternative sources causing weight loss 2. A patient of Type 1 Diabetes or type 2 Diabetes who has good control of glucose but consumes less calories than he needs loses weight . In addition associated thyroid disorders may also have some influence on weight . Continue reading >>
Unexplained Weight Loss With Diabetes
You might be aware that as a metabolic disorder, some forms of diabetes come with excessive weight. But diabetes might also cause a sudden drop in weight too. In fact, many patients who are ultimately diagnosed with diabetes first go to their doctor with concerns about unexplained weight loss. Several mechanisms are behind this symptom. Weight loss can occur as a consequence of high blood sugar, dehydration, muscle breakdown and problems with your thyroid. Video of the Day Although both type 1 and type 2 diabetes can involve fairly dramatic weight loss over several days at the onset of the disease, it tends to be more common among people with type 1. In both cases, the cause is that your body fails to adequately deal with insulin. The job of insulin is to transport glucose from the foods you eat into your cells to provide energy for all the work that’s required to keep you alive. However, most type 1 diabetics don’t produce insulin. Type 2 diabetics either don’t produce enough insulin or their bodies don’t respond to it properly. Consequently, even if you eat normally, that blood sugar simply builds up and gets excreted in your urine. This causes weight loss, but it could also damage your organs if you don't receive treatment. If you experience an unexplained weight loss, surpassing 5 percent of your body weight within days, see your health care provider as soon as possible. Another symptom of diabetes associated with weight loss is frequent urination. When you urinate more frequently and don’t drink enough to replace the lost fluid, you become dehydrated. Urination increases in diabetes, because your kidneys have to work harder to filter the excess glucose building up in your system. The increased glucose in the urine draws fluid from your tissues. When you l Continue reading >>
One Man's Weight Loss Was A Sign Of Type 2 Diabetes
Kim Palmaffy was diagnosed with diabetes at age 51. (KIM PALMAFFY) If you have type 2 diabetes, you may feel abnormally thirsty and have a need to urinate frequently. One other possibility? You may lose weight without even trying. If it sounds like a weight-loss dream come true, it's actually more of a nightmare. Because your body doesn't have enough insulin or is losing sensitivity to insulin, you can't shuttle blood sugar into muscle cells. Blood sugar rises to toxic levels and you begin to excrete that excess sugar into the urine. At this point some people may shed pounds without dieting. Kim Palmaffy, 61, a contractor in Maplewood, N.J., was close to 300 pounds when he began to show signs of type 2 diabetes ten years ago. At 5'10", he knew he needed to lose weight. And then it started happening all on its own. The pounds started flying off, sometimes up to three pounds a week. "I got down to like 250 pounds over a period of weeks." You may feel exhausted His clothes began to fit better, but Palmaffy was feeling terrible. "I couldn't sleep, I started to urinate all the time, and I was always thirsty." It began to interfere with his work. "I had to get off the roof and take a leak all the time, as dumb as it sounds," he says. A visit to his doctors showed that Palmaffy's blood glucose, the type of sugar the body uses for energy, was a whopping 450 mg/dL, four times what's considered normal on a fasting blood glucose test110 mg/dL. "He started me on a whole battery of medications; I found that the medications were very positive," he said. "We finally settled on Glucotrol (glipizide), five milligrams twice a day." He also takes a cholesterol-lowering drug. Palmaffy had to make some dietary changes to cope with the diagnosis. He found it wasn't that difficult. His Continue reading >>
Should I Worry About Weight Gain With Insulin?
I am almost 20 years old, have had type 1 diabetes for eight years, and use insulin glargine (Lantus). Should I try to lower the need for insulin to prevent weight gain? I haven't been gaining weight, but I am concerned that I'll get into a cycle of increased insulin dosages and weight gain. Continue reading >>
Type 2 Diabetes: How To Lose Weight
Weight loss is a common recommendation for treatment for type 2 diabetes. Many people are overweight when they’re first diagnosed, and that extra fat actually increases their insulin resistance (when their bodies can’t properly use the hormone insulin). By losing weight, people with type 2 diabetes can become less insulin resistant, and they’re able to use insulin better. (To learn more about how the hormone insulin works, read our article on how insulin regulates blood glucose levels.) If you’ve recently been diagnosed with type 2 diabetes and you're overweight, you should get started as soon as possible on a weight loss plan. It is important to work with a registered dietitian to help you figure out a plan that will work for you—a healthy meal plan, physical activity, and realistic goals will help you reach a healthy weight. There are many advantages to losing weight (and not just diabetes-related ones): Boost your energy level Lower your cholesterol levels (especially important for people with type 2 diabetes) Protect your heart (also important for people with diabetes, since heart-related complications are very common) Make it easier to control your blood glucose level As you may already know, losing weight can be a challenge, but don’t let that stop you. Do whatever you need to in order to stay motivated. It is the amount of calories we eat that contributes to weight gain. Make small changes. Learn portion sizes and reduce the amount of snacks in your day to reduce the total amount of calories you consume each day. Find cookbooks with healthier recipes using low-fat options. For a little fun, take our carb counting quiz to see how well you know the carb content of certain foods; this can help you make healthier choices. Work with a registered dietitian Continue reading >>
Losing Weight With Diabetes: What Prevents It And Causes Weight Gain
I recently was included in a discussion on a Facebook group for athletes with diabetes about how hard it can be to lose weight through exercise. While I would never claim to have all the answers on this topic, here are some ideas about what can make you gain weight or keep you from losing weight with diabetes, based on my decades of professional and personal experience with diabetes and weight management, and what you can do about it. Insulin My former graduate student with type 1 diabetes went on an insulin pump and promptly gained about 10 pounds, even though his blood glucose control improved only marginally. Why did this happen to him (and why does it happen to so many other insulin users)? As a naturally occurring anabolic hormone, insulin promotes the uptake and storage of glucose, amino acids, and fat into insulin-sensitive cells around your body (mainly muscle and fat cells). It doesn’t matter whether it’s released naturally, injected, or pumped—all insulin and insulin analogues have these same effects. Going on intensive insulin therapy is associated with fat weight gain (1), for people with both type 1 and type 2 diabetes. Some of the weight gain comes from that if you’re using insulin to keep your blood glucose in control, you’ll be keeping and storing all of the calories that you’re eating instead of losing some glucose through urine (during hyperglycemia). Unfortunately, this realization has led some people to try skipping or limiting their insulin use to help them lose weight (2), but that is a dangerous practice that can lead to loss of excess muscle mass and life-threatening conditions like DKA. The best way to balance your insulin use and your body weight, in my opinion, is to be physically active to keep your overall insulin levels lower. I Continue reading >>
Diabetes Detectives Â€“ Finding Uncommon Conditions Beverly Thomassian, Rn, Mph, Cde, Bc-adm
- Diabetes Educational Services Training Healthcare Professionals On State-of-the-Art Diabetes Care Another Downloadable Article from the Diabetes Educational Services Site This article provides health care professionals with strategies to detect common, yet often underdiagnosed, complications associated with hyperglycemia and diabetes. It also describes how medications, organ transplants, and chronic illnesses can cause hyperglycemia. Diabetes Educational Services Beverly Dyck Thomassian PO Box 3749 Chico, CA 95928 530 893-8635 [email protected] www.DiabetesEd.net Diabetes Detectives â€“ Finding Uncommon Conditions Beverly Thomassian, RN, MPH, CDE, BC-ADM Rebecca* has Type 2 diabetes. Her diabetes and weight were stable, but over the last three weeks, her blood sugars have been consistently elevated, up to 300 mg/dL, and she has gained 10 pounds. Rebecca takes two diabetes oral medications plus insulin injections three times a day, thyroid replacement therapy, a cholesterol medication, and a new medication for â€œmood swings.â€ Frustrated and depressed, Rebecca wants to get her diabetes and weight back under control. Since people with diabetes are at greater risk for a long list of comorbidities, health care professionals often double as detectives while uncovering complications.1 Several common, yet often underdiagnosed, complications are associated with diabetes. People with diabetes can also experience weight gain or weight loss, or complain of something not feeling right because of a variety of factors that warrant investigation. By improving their â€œdiabetes detectiveâ€ skills, health care professionals can help patients improve the management of their diabetes â€” and their quality of life. Unexplained weight gain If patients complain o Continue reading >>
Unexplained Weight Loss
Tweet Unexplained weight loss is the term used to describe a decrease in body weight that occurs unintentionally and can be a warning sign of diabetes. The amount you weigh is determined by a number of factors including age, your calorie intake and overall health. Once you reach middle adulthood, your weight should remain relatively stable from year to year. Losing or gaining a few pounds here and there is normal, but unexplained weight loss that is significant (10 lbs/4.5kg or more or over 5% of your body weight) or persistent may signal an underlying medical condition. Unexplained weight loss means weight loss that occurs without trying through dieting or exercising. What are the possible causes of unexplained weight loss? Unintentional or unexplained weight loss can be caused by a number of things, including depression, certain medication and diabetes. Potential causes of unexplained weight loss include: Addison’s disease Coeliac disease Chronic diarrhoea Dementia Diabetes mellitus Eating disorders (anorexia and bulimia) Exocrine Pancreatic Insufficiency HIV/AIDS Hypercalcemia Hyperthyroidism Malnutrition Medicines, including chemotherapy drugs, laxatives, and thyroid medications Parkinson’s disease Recreational drugs, including amphetamines and cocaine Tuberculosis Diabetes and sudden weight loss In people with diabetes, insufficient insulin prevents the body from getting glucose from the blood into the body's cells to use as energy. When this occurs, the body starts burning fat and muscle for energy, causing a reduction in overall body weight. Unexpected weight loss is often noticed in people prior to a diagnosis of type 1 diabetes but it may also affect people with type 2 diabetes. When to call your doctor If you have unintentionally lost more than 5% of your Continue reading >>
Keeping The Pounds On: Causes Of Unexplained Weight Loss
Our society is obsessed with weight, if you haven’t noticed. More than two thirds of US adults are overweight or obese, there are more diet books published than we can count, and, of course, we have the privilege of watching shows like The Biggest Loser to help keep us in line. And according to government statistics, more than 85% of people with Type 2 diabetes are overweight. So it stands to reason that much of the focus of managing Type 2 diabetes is based on reaching and staying at a healthy weight. It’s important to note that thin people can get diabetes too, and not just Type 1 diabetes. In a 2008 study published in the journal Diabetes Care, adults age 60 to 79 years old with a body-mass index (BMI) of less than 18.5 (which is considered to be underweight) were 30% more likely to get Type 2 diabetes than adults with a “normal” BMI of 18.5 to 24.9. In a society where being thin equates with beauty, youth, intelligence, and success, there is often little sympathy or patience for people who are too thin and who desperately want to gain weight. If you’ve struggled with losing weight and keeping it off, you know all too well how challenging that can be. People who want to gain weight often face the same kind of battle. And to have diabetes on top of that can make it doubly difficult. First things first: identify the cause If you have diabetes, are underweight, and would like to gain weight, it’s helpful to first have a talk with your doctor. Make sure there are no health or medical reasons for you being underweight (especially if you’ve recently lost weight without trying) such as having an overactive thyroid, a digestive disorder (such as Crohn disease), or cancer, for example. A physical exam, blood work, and other tests may be needed to rule out certai Continue reading >>
Weight And Diabetes
A balanced diet and an active lifestyle can help all kids maintain a healthy weight. For kids with diabetes, diet and exercise are even more important because weight can affect diabetes and diabetes can affect weight. This is true for kids and teens with type 1 diabetes or type 2 diabetes. In diabetes, the body doesn't use glucose properly. Glucose, a sugar, is the main source of energy for the body. Glucose levels are controlled by a hormone called insulin , which is made in the pancreas. In type 1 diabetes , the pancreas does not make enough insulin. Undiagnosed or untreated type 1 diabetes can cause weight loss. Glucose builds up in the bloodstream if insulin isn't available to move it into the body's cells. When glucose levels become high, the kidneys work to get rid of unused sugar through urine (pee). This causes weight loss due to dehydration and loss of calories from the sugar that wasn't used as energy. Kids who develop type 1 diabetes often lose weight even though they have a normal or increased appetite. Once kids are diagnosed and treated for type 1 diabetes, weight usually returns to normal. Developing type 1 diabetes isn't related to being overweight, but keeping a healthy weight is important. Too much fat tissue can make it hard for insulin to work properly, leading to both higher insulin needs and trouble controlling blood sugar. In type 2 diabetes , the pancreas still makes insulin, but the insulin doesn't work in the body like it should and blood sugar levels get too high. Most kids and teens are overweight when they're diagnosed with type 2 diabetes. Being overweight or obese increases a person's risk for developing type 2 diabetes. Also, weight gain in people with type 2 diabetes makes blood sugar levels even harder to control. People with type 2 di Continue reading >>
Unexplained Weight Loss? Why You Need To See A Doctor
All of us cangain or lose a pound or two; we indulge a little too much,and then we put in a few extra workouts. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy But if you havent tightened the belt on your diet or ramped up your exercise routine and your weight is still dropping, talk to your doctor. While weight loss of just a pound or two isnt a reason for concern, unexplained weight loss of 10 pounds or more may meansomething is wrong. It could be an early sign of diabetes . This weight loss can occur relatively quickly over a few weeks to a couple of months. Insulin is a hormone that allows your body to use glucose (sugar) for energy. If you have type 2 diabetes , your body doesnt use insulin effectively, and cant transport the glucose to the cells. Instead, it builds up in the blood. When the glucose doesnt arrive in your cells, your body thinks its starving and finds a way to compensate. It creates energy by burning fat and muscle at a rapid pace. This causes unexplained weight loss. Your kidneys also begin working overtime to eliminate the excess sugars in the blood. This uses additional energy and can cause damage to the kidneys. Type 1 diabetes has a similar pattern, but instead of being unable to use insulin, your body stops producing it altogether. Unexplained weight loss can occur in people who have type 2 diabetes, but its more commonly found in people with type 1 . Parents are often the first to notice the unusual weight loss in a child with type 1 diabetes. What othersymptoms should you watch for? Weight loss from diabetes is not usually a standalone symptom. It is typically accompanied by other signs and symptoms including: Continue reading >>
Is Weight Loss Caused By Diabetes Dangerous?
home / health & living center / diet & weight management a-z list / is weight loss caused by diabetes dangerous article Is Weight Loss Caused by Diabetes Dangerous? Medical Author: Ruchi Mathur, MD, FRCP(C) Ruchi Mathur, MD, FRCP(C) is an Attending Physician with the Division of Endocrinology, Diabetes and Metabolism and Associate Director of Clinical Research, Recruitment and Phenotyping with the Center for Androgen Related Disorders, Department of Obstetrics and Gynecology at Cedars-Sinai Medical Center. I have a friend that is 35 and has diabetes . For the past eightyears, his weight has always been in check and if anything he may have beena little overweight . Just recently, he has lost a lot of weight and he toldme that he weighs less than he did in high school. I think he looks toothin and I am concerned about his health with him being a diabetic. Shouldthere be a concern and what kind of advice can you give me to pass on tohim. We often assume weight loss is good and healthy. A slow steady intentional weight loss using nutritional change and exercise is associated with beneficial effects on the heart, blood pressure , and cholesterol levels . In addition, weight loss can reduce " insulin resistance " and makemuscles and fat tissues more sensitive to circulating insulin levels in the blood. What type of diabetes causes weight loss? A reduction in insulin resistance is problematic because insulin is needed tohelp glucose enter these tissues to be metabolized. If these tissues areresistant to insulin, higher than normal levels are needed for this processto occur. This is often the case in Type 2 diabetes . As a result, a viciouscycle occurs, the higher the insulin levels are, the harder it is to loseweight (insulin is anabolic, and is a hormone that likes to store Continue reading >>
3 Simple Tricks To Not Let Type 1 Diabetes Ruin Your Diet & Weight Loss Goals
“Type 1 diabetes stops me from losing weight” is the number one excuse I hear when people say they are struggling to lose weight (seriously, my Instagram inbox is flooded with this statement/question). And while insulin can be a tricky hormone to work around when losing weight with type 1 diabetes, I’ve found that 99% of the time it is because their general dieting techniques are off. Before reading my three nutrition tricks for losing weight with type 1 diabetes, make sure you are doing the following: Weighing and tracking your food intake (My Fitness Pal) Eating toward a specifically calculated calorie/macronutrient (IIFYM.com) Combining aerobic & anaerobic training If you aren’t following the above, it is most likely not your diabetes that is stoping you from losing weight– it is the lack of clarity and preparation for your goals. Once you solidify your general nutrition foundation, now you can go to the next specific tactics related to diabetes management that will help you stay on track. Carb Reserve There is nothing worse than being on track to hit your calories and macros perfectly then being engulfed by an endless food-frenzy brought on by a bad low. Hypoglycemia is a major reason why people go over their carb & calorie limits for the day as you need carbs to fix the low. But there is a way to work around this issue: Implementing a carb reserve. A carb reserve is when you reserve 15-30 grams of your total daily carbs for a low blood sugar attack. For example, if your weight loss goal calls for 100 grams of carbs a day, act like you only have 85 grams of carbs for the day and keep 15 grams of carbs just in case of a low. That way, when you treat your low blood sugar, you aren’t ruining your daily goals. Proper preparation prevents poor performance! An Continue reading >>