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How Does Diabetes Damage Your Kidneys?

Diabetic Kidney Disease

Diabetic Kidney Disease

What is diabetic kidney disease? Diabetic kidney disease is a type of kidney disease caused by diabetes. Diabetes is the leading cause of kidney disease. About 1 out of 4 adults with diabetes has kidney disease.1 The main job of the kidneys is to filter wastes and extra water out of your blood to make urine. Your kidneys also help control blood pressure and make hormones that your body needs to stay healthy. When your kidneys are damaged, they can’t filter blood like they should, which can cause wastes to build up in your body. Kidney damage can also cause other health problems. Kidney damage caused by diabetes usually occurs slowly, over many years. You can take steps to protect your kidneys and to prevent or delay kidney damage. What are other names for diabetic kidney disease? Diabetic kidney disease is also called DKD, chronic kidney disease, CKD, kidney disease of diabetes, or diabetic nephropathy. How does diabetes cause kidney disease? High blood glucose, also called blood sugar, can damage the blood vessels in your kidneys. When the blood vessels are damaged, they don’t work as well. Many people with diabetes also develop high blood pressure, which can also damage your kidneys. Learn more about high blood pressure and kidney disease. What increases my chances of developing diabetic kidney disease? Having diabetes for a longer time increases the chances that you will have kidney damage. If you have diabetes, you are more likely to develop kidney disease if your blood glucose is too high blood pressure is too high African Americans, American Indians, and Hispanics/Latinos develop diabetes, kidney disease, and kidney failure at a higher rate than Caucasians. You are also more likely to develop kidney disease if you have diabetes and smoke don’t follow your di Continue reading >>

Diabetes And Kidney Disease

Diabetes And Kidney Disease

Diabetes is a disease that is caused by the lack of insulin in the body or the body's inability to properly use normal amounts of insulin. The body converts the food we eat into sugar (glucose). The body needs this sugar, in the form of energy, to perform its functions. The hormone insulin, produced by the pancreas, regulates the amount of glucose (sugar) in the blood. If the body lacks insulin or does not use the insulin properly, then this imbalance results in high blood sugar. Eventually many unhealthy changes can occur in different body organs, including the kidneys. How diabetes affects the kidneys Damage to blood vessels Even with the use of injected insulin, people who have had diabetes for some time often suffer from damage to the small blood vessels of the body. This may cause damage to the retina of the eye and result in loss of vision. Also, the delicate blood vessels in the filters of the kidney may be damaged. At the early stage, this damage is shown by finding protein in the urine. Sometimes at a later stage, so much protein is lost from the blood that water from the blood moves into the body tissues and causes swelling (edema). After a number of years, the kidneys' filters can become so damaged by diabetes that the kidneys fail. Damage to nerves Diabetes can also damage the nerves in many parts of the body. When the bladder is affected, it may be difficult to pass urine. The pressure from urine building up in the bladder can damage the kidneys. Infections The urine of people with diabetes has a high sugar content. This encourages the growth of bacteria and kidney infections may occur. People with diabetes must take special care to avoid infections and have them treated immediately. Types of diabetes There are several types of diabetes. The most common one Continue reading >>

What Is Diabetic Nephropathy?

What Is Diabetic Nephropathy?

Diabetic nephropathy -- kidney disease that results from diabetes -- is the number one cause of kidney failure. Almost a third of people with diabetes develop diabetic nephropathy. People with diabetes and kidney disease do worse overall than people with kidney disease alone. This is because people with diabetes tend to have other long-standing medical conditions, like high blood pressure, high cholesterol, and blood vessel disease (atherosclerosis). People with diabetes also are more likely to have other kidney-related problems, such as bladder infections and nerve damage to the bladder. Kidney disease in type 1 diabetes is slightly different than in type 2 diabetes. In type 1 diabetes, kidney disease rarely begins in the first 10 years after diagnosis of diabetes. In type 2 diabetes, some patients already have kidney disease by the time they are diagnosed with diabetes. There are often no symptoms with early diabetic nephropathy. As the kidney function worsens, symptoms may include: Swelling of the hands, feet, and face Trouble sleeping or concentrating Poor appetite Itching (end-stage kidney disease) and extremely dry skin Drowsiness (end-stage kidney disease) Abnormalities in the hearts' regular rhythm, because of increased potassium in the blood Muscle twitching As kidney damage progresses, your kidneys cannot remove the waste from your blood. The waste then builds up in your body and can reach poisonous levels, a condition known as uremia. People with uremia are often confused and occasionally become comatose. Certain blood tests that look for specific blood chemistry can be used to diagnose kidney damage. It also can be detected early by finding protein in the urine. Treatments are available that can help slow progression to kidney failure. That's why you should Continue reading >>

How Does Diabetes Damage The Kidney?

How Does Diabetes Damage The Kidney?

Disclaimer: These stories are a part of the sponsored section created for Mehfil-e-Taj event. Kidneys are remarkable organs. Inside them are millions of small units known as nephrons that act as filters. Their job is to remove waste products from the blood. Sometimes this filtering system breaks down. Diabetes can damage the kidneys and cause them to fail. Failing kidneys lose their ability to filter out waste products, resulting in kidney disease. Diabetic kidney disease (diabetic nephropathy) is a complication that occurs in some people with diabetes. In this condition the filters of the kidneys, the glomeruli (part of nephron), become damaged. Because of this the kidneys 'leak' abnormal amounts of protein from the blood into the urine. The main protein that leaks out from the damaged kidneys is albumin. In normal healthy kidneys only a tiny amount of albumin is found in the urine. A raised level of albumin in the urine is the typical first sign that the kidneys have become damaged by diabetes. Diabetic kidney disease is divided into two main categories, depending on how much albumin is lost through the kidneys: Microalbuminuria- This is when the amount of albumin that leaks into the urine is between 30 and 300 mg per day. It is sometimes called incipient nephropathy. Proteinuria- This is when the amount of albumin that leaks into the urine is more than 300 mg per day. It is sometimes called macroalbuminuria or overt nephropathy. How does diabetic kidney disease develop and progress? A raised blood sugar (glucose) level that occurs in people with diabetes can cause albumin to leak into the urine. In addition, the raised blood glucose level may cause some proteins in the glomeruli to link together. These 'cross-linked' proteins can trigger a localised scarring process. Continue reading >>

Diabetes And Kidney Failure

Diabetes And Kidney Failure

One of the causes of kidney failure is diabetes mellitus, a condition characterised by high blood glucose (sugar) levels. Over time, the high levels of sugar in the blood damage the millions of tiny filtering units within each kidney. There is no cure, and treatment must become ever more aggressive as the kidneys deteriorate towards failure. Treatment options include medications, dialysis and kidney transplant. On this page: The main job of the kidneys is to remove waste from the blood and return the cleaned blood back to the body. Kidney failure means the kidneys are no longer able to remove waste and maintain the level of fluid and salts that the body needs. One cause of kidney failure is diabetes mellitus, a condition characterised by high blood glucose (sugar) levels. Over time, the high levels of sugar in the blood damage the millions of tiny filtering units within each kidney. This eventually leads to kidney failure. Around 20 to 30 per cent of people with diabetes develop kidney disease (diabetic nephropathy), although not all of these will progress to kidney failure. A person with diabetes is susceptible to nephropathy whether they use insulin or not. The risk is related to the length of time the person has diabetes. There is no cure for diabetic nephropathy, and treatment is lifelong. Another name for the condition is diabetic glomerulosclerosis. People with diabetes are also at risk of other kidney problems, including narrowing of the arteries to the kidneys, called renal artery stenosis or renovascular disease. Symptoms of kidney failure For people with diabetes, kidney problems are usually picked up during a check-up by their doctor. Occasionally, a person can have type 2 diabetes without knowing it. This means their unchecked high blood sugar levels may be Continue reading >>

Diabetic Kidney Disease

Diabetic Kidney Disease

Diabetic kidney disease is a complication that occurs in some people with diabetes. It can progress to kidney failure in some cases. Treatment aims to prevent or delay the progression of the disease. Also, it aims to reduce the risk of developing cardiovascular diseases such as heart attack and stroke which are much more common than average in people with this disease. To find out more about the kidneys and urine see also separate leaflet called The Kidneys and Urinary Tract. What is diabetic kidney disease? Diabetic kidney disease (diabetic nephropathy) is a complication that occurs in some people with diabetes. In this condition the filters of the kidneys, the glomeruli, become damaged. Because of this the kidneys 'leak' abnormal amounts of protein from the blood into the urine. The main protein that leaks out from the damaged kidneys is called albumin. In normal healthy kidneys only a tiny amount of albumin is found in the urine. A raised level of albumin in the urine is the typical first sign that the kidneys have become damaged by diabetes. Diabetic kidney disease is divided into two main categories, depending on how much albumin is lost through the kidneys: Microalbuminuria: in this condition, the amount of albumin that leaks into the urine is between 30 and 300 mg per day. It is sometimes called incipient nephropathy. Proteinuria: in this condition the amount of albumin that leaks into the urine is more than 300 mg per day. It is sometimes called macroalbuminuria or overt nephropathy. How does diabetic kidney disease develop and progress? A raised blood sugar (glucose) level that occurs in people with diabetes can cause a rise in the level of some chemicals within the kidney. These chemicals tend to make the glomeruli more 'leaky' which then allows albumin to lea Continue reading >>

Diabetes And Renal Failure: Everything You Need To Know

Diabetes And Renal Failure: Everything You Need To Know

Unfortunately, renal failure or nephropathy (commonly referred to as kidney failure) and unmanaged diabetes go hand in hand. In addition, 50 percent of people with diabetes will experience some form of kidney damage in their lifetime, even if they never experience kidney failure or end up on dialysis. In this article, we will look at how renal failure and insufficiency can have an impact on people with diabetes, and how people with diabetes can avoid renal failure and dialysis. We will look at risk factors, causes, and symptoms, as we explore the relationship between renal failure, diabetes, and high blood glucose. We will also look at what happens to a person with diabetes when their kidneys fail. We will discuss dialysis and kidney transplantation. First, let’s see what Lydia had to say when she contacted TheDiabetesCouncil. Lydia’s story Lydia had received a laboratory result from her doctor that was very alarming to her. She had an excess amount of protein in her urine, usually an early sign of kidney damage. He informed Lydia that her kidneys were being affected by her diabetes, and she needed to work on self-managing her diabetes. He ordered some more tests to further look at her kidneys. Was Lydia headed to the kidney dialysis center? Her friend Tracey, whom she’d met in a diabetes support group had been the first person she knew who was on dialysis. Tracey seemed to have a very difficult life in and out of the dialysis center. Lydia was afraid to end up like Tracey. Lydia knew that she hadn’t been efficiently self-managing her diabetes. Her A1C had been greater than 8 percent a few times over the last few years. While most of the time she kept it around 7.5 percent, she was aware that her doctor wanted her to get it below 7 percent, and keep it there in Continue reading >>

Diabetes And Kidney Damage (nephropathy)

Diabetes And Kidney Damage (nephropathy)

Over time, high blood sugars can cause damage to the kidneys. This is called kidney disease, kidney damage or nephropathy. Your kidneys contain special filters that help clean your blood, remove waste, and control your fluid balance. These filters are called nephrons. Over time, high blood sugar can damage them and cause them to leak protein, called albumin, into your urine. You may experience no symptoms if the damage is minor. However, the extra protein (albumin) can show up on routine blood work conducted by your doctor. Untreated, damage to your kidneys can grow until kidney dialysis or a kidney transplant are necessary. Long-term studies show that achieving your HbA1c targets dramatically lowers your risk for kidney disease.1 The National Institute of Health’s (NIH) Medline Plus center states that kidney damage is more likely to occur if you: Have uncontrolled blood sugar Have high blood pressure Have type 1 diabetes that began before you were 20 years old Have family members who also have diabetes and kidney problems Smoke Are African American, Mexican American, or Native American See your healthcare provider yearly to get tested for any early signs of kidney damage or signs that there could soon be damage to the kidneys. There are different tests available that your healthcare provider should use. Urine albumin test (microalbuminuria): This involves a urine sample which is tested for the presence of a protein called albumin which may leak into the urine from the kidneys. This may indicate the presence of kidney damage. Blood urea nitrogen test (BUN): This involves a sample of blood from a vein and checks kidney function. Serum creatinine: This can be done by urine or blood sample and measures creatinine which should normally be removed by your kidneys so testin Continue reading >>

Diabetes And Your Eyes, Heart, Nerves, Feet, And Kidneys

Diabetes And Your Eyes, Heart, Nerves, Feet, And Kidneys

Diabetes is a serious disease that can affect your eyes, heart, nerves, feet and kidneys. Understanding how diabetes affects your body is important. It can help you follow your treatment plan and stay as healthy as possible. If your diabetes is not well controlled, the sugar level in your blood goes up. This is called “hyperglycemia” (high blood sugar). High blood sugar can cause damage to very small blood vessels in your body. Imagine what happens to sugar when it is left unwrapped overnight. It gets sticky. Now imagine how sugar “sticks” to your small blood vessels and makes it hard for blood to get to your organs. Damage to blood vessels occurs most often in the eyes, heart, nerves, feet, and kidneys. Let’s look at how this damage happens. Eyes. Having high levels of sugar in your blood for a long time can harm the tiny blood vessels in your eyes. This can result in vision problems or blindness. Heart. High blood sugar may also harm larger blood vessels in your body that supply oxygen to your heart and brain. Fat can build up in the blood vessels as well. This can lead to a heart attack or stroke. Nerves. Nerves carry important messages between your brain and other parts of your body. Having high levels of sugar in your blood for many years can damage the blood vessels that bring oxygen to some nerves. Damaged nerves may stop sending pain signals. Feet. Diabetes can harm your feet in two ways. First, it can damage your body’s nerves. Nerve damage stops you from feeling pain or other problems in your feet. Another way that diabetes can cause damage to your feet is from poor blood circulation. Poor blood flow makes it hard for a sore or infection to heal. If sores don’t heal and get infected, it can lead to amputation. Kidneys. Think of your kidneys like Continue reading >>

Bladder & Kidneys

Bladder & Kidneys

Kidney and bladder damage is a complication of diabetes. People with diabetes are at risk of bladder and kidney infections, kidney failure and dialysis Maintaining good blood glucose control and keeping your blood pressure at a healthy level will reduce this risk Annual kidney health checks are recommended Kidney Disease Kidney disease occurs when the nephrons inside your kidneys, which act as blood filters, are damaged. This leads to the build up of waste and fluids inside the body. If kidney disease is not diagnosed, it can lead to serious complications including kidney failure, which requires dialysis or a kidney transplant to keep you alive. Kidney disease and diabetes Each kidney contains up to one million nephrons, the filtering units of the kidneys. Inside a nephron is a tiny set of looping blood vessels called the glomerulus. Diabetes can damage the kidney filters, leading to diabetic kidney disease, or diabetic nephropathy. If kidney disease is found early, medication, dietary and lifestyle changes can increase the life of your kidneys and keep you feeling your best for as long as possible. Symptoms In some cases diabetic kidney disease causes the kidney filters to become blocked and stop working, which results in kidney failure. Symptoms of kidney failure may be general and can include: changes in the amount and number of times urine is passed blood in the urine tiredness loss of appetite difficulty sleeping headaches lack of concentration shortness of breath nausea and vomiting Controlling blood sugar levels can slow down the development of diabetic kidney disease. Kidney health check It is very important that diabetic kidney disease is detected early as treatment can help to increase the life of the kidneys. Your health care team can give you practical advic Continue reading >>

Kidney Disease Of Diabetes

Kidney Disease Of Diabetes

Kidney Disease of Diabetes Facts* *Kidney Disease of Diabetes Facts Medically Edited by: Melissa Conrad Stöppler, MD Type 2 Diabetes Diagnosis, Treatment, Medication Medical Author: Melissa Conrad Stoppler, MD Medical Editor: Ruchi Mathur, MD, FRCP(C) Proper nutrition is essential for anyone living with diabetes. Control of blood glucose levels is only one goal of a healthy eating plan for people with diabetes. A diet for those with diabetes should also help achieve and maintain a normal body weight as well as prevent heart and vascular disease, which are frequent complications of diabetes. There is no prescribed diet plan for those with diabetes. Rather, eating plans are tailored to fit an individual's needs, schedules, and eating habits. A diabetes diet plan must also be balanced with the intake of insulin and oral diabetes medications. In general, the principles of a healthy diabetes diet are the same for everyone. Consumption of a variety of foods including whole grains, fruits, non-fat dairy products, beans, and lean meats or vegetarian substitutes, poultry and fish is recommended to achieve a healthy diet. Each year in the United States, more than 100,000 people are diagnosed with kidney failure, a serious condition in which the kidneys fail to rid the body of wastes. Kidney failure is the final stage of chronic kidney disease (CKD). Diabetes is the most common cause of kidney failure, accounting for nearly 44 percent of new cases. Even when diabetes is controlled, the disease can lead to chronic kidney disease and kidney failure. Most people with diabetes do not develop chronic kidney disease that is severe enough to progress to kidney failure. Nearly 24 million people in the United States have diabetes, and nearly 200,000 people are living with kidney failure a Continue reading >>

How To Protect Your Kidneys When You Have Diabetes

How To Protect Your Kidneys When You Have Diabetes

Reviewed by Michael Dansinger, MD When you have diabetes, it's key to take care of your kidneys. They do an important job filtering waste and removing it from your blood. Diabetes can hurt the kidneys and cause them to stop working. It's the main cause of kidney failure. How Diabetes Damages Kidneys With diabetes, you have high blood sugar. Those high levels make your kidneys work extra hard to filter your blood. Over time, working that hard can damage your kidneys, causing small amounts of protein to leak into your urine. Damage can get worse, and more protein leaks into your urine. Your blood pressure can start to rise. Waste materials will build up in your blood. If you don't treat it, your kidneys won't work anymore. If your kidneys fail completely, you'll need to have your blood filtered by a machine (dialysis) or have a kidney transplant. Can You Tell If You Have Kidney Damage? There are very few symptoms of kidney disease until your kidneys have almost stopped working. One of the earliest signs is fluid buildup. You might have swollen ankles, weight gain, or you may pee more often. You may also have a hard time sleeping or concentrating. You may not be hungry, or you may have an upset stomach. You may just feel weak. These symptoms aren't very specific. That's why it's important to see your doctor regularly for these kidney-related tests if you have diabetes. Blood pressure. High blood pressure can be a sign of kidney problems. You should have yours checked at every health care visit. Your doctor will tell you what levels are healthy for you. Blood tests. The estimated glomerular filtration rate (eGFR) checks how well your kidneys are able to filter your blood. Urine tests. Your doctor will check for levels of protein, creatinine, and albumin. These levels can sh Continue reading >>

Kidney Damage With Diabetes

Kidney Damage With Diabetes

The kidneys are the body's filtering system. They pull waste and extra water from the blood and take it out of the body as urine. The filtering parts of the kidneys are called nephrons. Nephrons have many small blood vessels in them. High blood sugar levels and uncontrolled high blood pressure can damage these small blood vessels. Damage to the nephrons is called nephropathy. In the early stages of nephropathy, the body doesn't give any warning signs that the damage is happening. Fortunately, a quick urine test, called a microalbuminuria test, can find early signs of nephropathy. Stages of Kidney Disease Diabetes can lead to changes in the kidneys that happen in stages. In the early stages, stages 1 through 3, the kidneys are able to make up for the damage and there aren't any obvious signs that the damage is happening. When enough damage occurs, in stages 4 and 5, the kidneys lose their ability to filter and cleanse the blood. Stage 1: In this very early stage, the blood flow through the kidneys increases and the kidneys get slightly larger. Good blood pressure and blood sugar control are very important at this stage to help prevent any more changes. Stage 2: The kidneys start showing damage in stage 2, as small amounts of protein (albumin) begin to leak into the urine. The kidneys will normally try to keep from filtering protein into the urine because protein is such an important building block for the body. Albumin in the urine in this small amount (200 micrograms or less per milligram of urine) is found by a test called the microalbumin urine test, done at the lab. At this stage, treatment includes quitting all tobacco products, controlling high blood pressure, keeping blood sugar levels as close to normal as possible, and using an ACE inhibitor or similar drug. Doi Continue reading >>

Diabetes - A Major Risk Factor For Kidney Disease

Diabetes - A Major Risk Factor For Kidney Disease

Diabetes mellitus, usually called diabetes, is a disease in which your body does not make enough insulin or cannot use normal amounts of insulin properly. Insulin is a hormone that regulates the amount of sugar in your blood. A high blood sugar level can cause problems in many parts of your body. The most common ones are Type 1 and Type 2. Type 1 diabetes usually occurs in children. It is also called juvenile onset diabetes mellitus or insulin-dependent diabetes mellitus. In this type, your pancreas does not make enough insulin and you have to take insulin injections for the rest of your life. Type 2 diabetes, which is more common, usually occurs in people over 40 and is called adult onset diabetes mellitus. It is also called non insulin-dependent diabetes mellitus. In Type 2, your pancreas makes insulin, but your body does not use it properly. The high blood sugar level often can be controlled by following a diet and/or taking medication, although some patients must take insulin. Type 2 diabetes is particularly prevalent among African Americans, American Indians, Latin Americans and Asian Americans. With diabetes, the small blood vessels in the body are injured. When the blood vessels in the kidneys are injured, your kidneys cannot clean your blood properly. Your body will retain more water and salt than it should, which can result in weight gain and ankle swelling. You may have protein in your urine. Also, waste materials will build up in your blood. Diabetes also may cause damage to nerves in your body. This can cause difficulty in emptying your bladder. The pressure resulting from your full bladder can back up and injure the kidneys. Also, if urine remains in your bladder for a long time, you can develop an infection from the rapid growth of bacteria in urine that h Continue reading >>

Diabetic Kidney Problems

Diabetic Kidney Problems

If you have diabetes, your blood glucose, or blood sugar, levels are too high. Over time, this can damage your kidneys. Your kidneys clean your blood. If they are damaged, waste and fluids build up in your blood instead of leaving your body. Kidney damage from diabetes is called diabetic nephropathy. It begins long before you have symptoms. People with diabetes should get regular screenings for kidney disease. Tests include a urine test to detect protein in your urine and a blood test to show how well your kidneys are working. If the damage continues, your kidneys could fail. In fact, diabetes is the most common cause of kidney failure in the United States. People with kidney failure need either dialysis or a kidney transplant. You can slow down kidney damage or keep it from getting worse. Controlling your blood sugar and blood pressure, taking your medicines and not eating too much protein can help. NIH: National Institute of Diabetes and Digestive and Kidney Diseases Continue reading >>

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