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Diabetes And Osmosis

Why Does Diabetes Cause Excessive Urination And Thirst? A Lesson On Osmosis

Why Does Diabetes Cause Excessive Urination And Thirst? A Lesson On Osmosis

A TABA Seminar on Diabetes I have the pleasure of being an executive member of the Toronto Applied Biostatistics Association (TABA), a volunteer-run professional organization here in Toronto that organizes seminars on biostatistics. During this past Tuesday, Dr. Loren Grossman from the LMC Diabetes and Endocrinology Centre generously donated his time to deliver an introductory seminar on diabetes for biostatisticians. The Institute for Clinical and Evaluative Sciences (ICES) at Sunnybrook Hospital kindly hosted us and provided the venue for the seminar. As a chemist and a former pre-medical student who studied physiology, I really enjoyed this intellectual treat, especially since Loren was clear, informative, and very knowledgeable about the subject. Diabetes Diabetes is a group of metabolic diseases that are characterized by a high concentration of glucose in the bloodstream. Glucose is a common monomer of carbohydrates that exists in many foods, including bread, pasta, rice, fruits, vegetables, and refined sugar. It provides the fuel for the cells of our bodies to function. Chemical Structures of Open-Chain and Cyclic Glucose For a variety of reasons that distinguish the different types of diabetes, diabetics cannot absorb glucose normally, leaving an excess of glucose in the bloodstream. Diabetes leads to many health problems, like kidney failure, blindness, heart attacks and strokes. The Growing Prevalence of Diabetes It was interesting but sad for me to learn about the increased prevalence of diabetes in North America and around the world. Loren commented that diabetes was a specialized niche area in endocrinology when he began his research in this field over 25 years ago, but it is now a major area of study in medical research because of its epidemic proportions. Continue reading >>

Sugar Detox

Sugar Detox

Home > Products > Wellness > Waters > Body Harmonize sugars effects on your body and organs with this multitasking holistic supplement! Curb that sweet tooth craving with frequencies designed to harmonize sugar regulation and artificial sweeteners or balance the pancreas and harmonize nerve damage associated with diabetes for an all-in-one, sugar-balancing supplement. You must enter the code provided by your skincare professional upon checkout to purchase. Contact Us to find a retailer near you or click here to see our authorized online resellers. Harmonize sugars effects on your body and organs with this multitasking holistic supplement! Curb that sweet tooth craving with frequencies designed to harmonize sugar regulation and artificial sweeteners or balance the pancreas and harmonize nerve damage associated with diabetes for an all-in-one, sugar-balancing supplement. Individuals with known medical conditions or currently on medication should consult a physician before using. While taking this water, it is important to frequently monitor your blood sugar levels. If you experience any symptoms, please contact your doctor. American Spa | Professional's Choice 2017 American Spa | Professional's Choice 2016 These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat or replace treatment, diagnose, cure or prevent any disease. If you have a medical condition, consult a doctor. Take 5 pumps AM and PM. If more than 175 lbs. take 7 pumps. My dad was diagnosed with diabetes a couple months ago. Was given medication and told to return in 2 months for recheck. Went today and the doctor told him his blood work looked better than it has in years. Said to keep taking your medication your no longer diabetic. It's working. My da Continue reading >>

Diabetes Mellitus - Osmosis

Diabetes Mellitus - Osmosis

Anatomy and physiology of the female reproductive system Diabetes mellitus type 1 is a form of diabetes mellitus that results from the autoimmune destruction of the insulin-producing beta-cells in the pancreas. The subsequent lack of insulin leads to increased blood and urine glucose. The classical symptoms are polyuria, polydipsia, polyphagia, and weight loss. Diabetes mellitus is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger. If left untreated, diabetes can cause many complications. Acute complications include diabetic ketoacidosis and nonketotic hyperosmolar coma. Serious long-term complications include cardiovascular disease, stroke, chronic kidney failure, foot ulcers, and damage to the eyes. Diabetic ketoacidosis (DKA) is a potentially life-threatening complication in people with diabetes mellitus. It happens predominantly in those with type 1 diabetes, but it can occur in those with type 2 diabetes under certain circumstances. DKA results from a shortage of insulin; in response the body switches to burning fatty acids and producing acidic ketone bodies that cause most of the symptoms and complications. Vomiting,dehydration,deep gasping breathing,confusionand occasionallycomaare typical symptoms. It is distinguished from other, rarer forms ofketoacidosisby the presence of highblood sugarlevels. Diabetes mellitus type 2 is characterized by hyperglycemia, insulin resistance, and relative impairment in insulin secretion. It is a common disorder with a prevalence that rises markedly with increasing degrees of obesity. The prevalence has risen alarmingly in the past decade, in large part linked to the trends in obesity and Continue reading >>

Osmosis, Cell Transport And Diabetes

Osmosis, Cell Transport And Diabetes

The movement of molecules from an area of high concentration to low concentration A membrane like the cell membrane that lets some small items pass through and other large molecules remain behind. The movement of water through a selective permeable membrane from an area of high water concentration (low solute) to an area of low water concentration (high solute) Item that is dissolved by a solvent. Water is a universal solvent capable of dissolving many things that are ionically bonded or polar. Contains a high amount of solute and a low amount of water. Water will move toward hypertonic environment. Contains a low amount of solute and high amount of water. May even be pure distilled water. Water will leave hypotonic environment to go to hypertonic environment. Amount of solute and water equal on either side of the membrane so no net movement of water. Cells in a hypertonic environment will lose mass and shrivel. Cells in a hypotonic environment will gain mass, swell and potentially burst. Cells in an isotonic environment will function normally. Protein channels like aquaporins, glucose channels and ion channels open up when triggered to move materials from a high concentration to a low concentration (along normal diffusion concentration gradient) Normal diffusion through a membrane of small particles like oxygen and CO2 from a high concentration to a low (normal diffusion gradient) Protein pumps move AGAINST the normal concentration gradient, from low concentration to high concentration. This occurs for Potassium (K+) and Sodium (Na+) to allow for nerve signals and muscle contractions. REQUIRES ATP energy Condition where insulin cannot be produced by pancreas and must be injected in order for blood glucose to go into cells. Caused by severe disease, or autoimmune probl Continue reading >>

Endocrine Reading 5

Endocrine Reading 5

Life for a person with diabetes mellitus means constant awareness of the illness--one or two insulin shots a day, frequent finger punctures to monitor blood glucose level, a restrictive diet, and concern over complications, which include loss of vision, leg ulcers, and kidney damage. The many symptoms of diabetes reflect disturbances in carbohydrate, protein, and fat metabolism. Diabetes in Latin means increased urine output, and mellitus means honey, referring to urine's sugar content. Lack of insulin decreases movement of glucose into skeletal muscle and adipose cells, inhibiting glycogen formation. As a result, blood sugar concentration rises (hyperglycemia). When blood sugar reaches a certain level, the kidneys begin to excrete the excess, and glucose appears in the urine (glycosuria). The osmotic pressure of water follows the glucose by osmosis, causing excess urinary water loss. As a result, the person becomes dehydrated and very thirsty. Diabetes mellitus decreased protein synthesis, causing tissues to waste away as glucose-starved cells use protein as an energy source. Weight falls and wounds cannot heal. Fatty acids accumulate in the blood as a result of decreased fat synthesis and storage. Ketone bodies, a by-product of fat metabolism, also increase in the blood. They are excreted in the urine as sodium salts, and large quantities of water follow by osmosis, intensifying dehydration and lowering sodium concentration in the blood. Accumulation of ketones and loss of sodium ions lead to metablic acidosis, a condition that lowers the pH of body fluids. Acidosis and dehydration adversely affect brain neurons. Without treatment (insulin replacement), the person becomes disoriented and may enter a diabetic coma and die. There are two common forms of diabetes mellit Continue reading >>

Diabetes: When Blood Glucose Control Fails

Diabetes: When Blood Glucose Control Fails

Editor’s note: Physicians have a special place among the thinkers who have elaborated the argument for intelligent design. Perhaps that’s because, more than evolutionary biologists, they are familiar with the challenges of maintaining a functioning complex system, the human body. With that in mind, Evolution News is delighted to offer this series, “The Designed Body.” For the complete series, see here. Dr. Glicksman practices palliative medicine for a hospice organization. In my last article, we saw that the body uses glucose for its energy needs and after a meal, stores it within the liver and other organs in the form of glycogen and fat. Since the brain cannot store glucose, it is totally dependent on the liver’s ability to release this stored energy several hours after a meal. Real numbers have real consequences and if the blood glucose drops below 50 units, symptoms of brain malfunction, like weakness, dizziness, and problems with concentration occur. If it drops below 40 units, then problems with speaking and increased confusion and drowsiness occur. If it goes below 30 units, seizures and coma result. And when the blood glucose drops under 20 units, brain death is certain. Being able to control the blood glucose is critical for human survival and it doesn’t just happen because we eat and drink sugary things. It requires the body to know when to store glucose and when to release it so the brain is always receiving what it needs. The body uses what biochemist Michael Behe would call an irreducibly complex system, involving beta and alpha cells in the pancreas that controls its blood glucose. After a meal, the beta cells, using glucosensors, react to a rise in blood glucose above 70 units by releasing insulin. Insulin travels in the blood and attaches to Continue reading >>

Diabetic Lens Osmosis

Diabetic Lens Osmosis

New Member T2 -2 weeks ago march 4 2008 grandmother was T1 i just found out two weeks ago that i have high blood sugar.my sugars were 19 20 27 16 all over the map.now im on a drug metforman,counting my carbs, and walking.my sugars are comming down to 10 8 even 6. i find the whole thing pretty scary ,also my eyes have been quite blurry for the last week and half. i think they call it, Diabetic Lens Osmosis im having quite a hard time with it. can any give me more infoe please. yes, our eyes are blurry for the first little while when we are diagnosed it takes 3 months of good bg control before your vision will be 'normal' again what do you do in the mean time. I mean 3 months is a long time to wait and hope your eyes clear up. Before I was dx .. my vision was so bad( nearsighted) I had to go get glasses... Now my eyes have shifted to the complete opposite (farsighted) and I had to go buy cheap "reading" glasses because I cant see .. period. Everything is a blur. I cannot see to drive, computer, TV or read without the "reading " glasses. When I was diagnosed my eye sight was fine throughout most of the day, but regualarly around 7pm my vision would blur and the longer I tried to focus the blurrier I got. It only happened when I tried to read or look at something close up, so I'd not do any work during that time and do something like watch tv or listen to music. For me it cleared up in about of week. It can take months for the eyes to stop changing shape, but it usually doesn't take that long for your vision to improve. The eye is very flexible and can compensate for it's changing shape slightly, especially if you are younger. Insulin (avg): 19.8 U (35% bolus); CHO (avg): 87g; BG (avg): 97 mg/dl; SD: 31 Tests (avg): 5.1; High: 168; Low: 51; highs>140: 3; lows<70: 10 Friend Continue reading >>

Used Reverse Osmosis Maple Syrup

Used Reverse Osmosis Maple Syrup

Joslin Diabetes Center Treatment Diabetes Cat condo bitter melon is very suitable for type 2 diabetes mellitus with insulin resistance.Joslin Diabetes La diabetes ocupa el primer lugar en nmero de defunciones por ao en Mxico seala la Organizacin Mundial de la las cifras de enfermos son alarmantes (the loss of too much body water). Used Reverse Osmosis Maple Syrup there are no published studies of the effectiveness of low-level infrared therapy for treatment of making rice pudding with almond milk diabetic peripheral neuropathy. The patient had never worn a pump before but had d 1. Diets high in refined sugars release more insulin thereby allowing less stored fat to be burned. Sign Up for the Dixie Diners Club High-low alarm reference card It allows your doctor to customize your action plan empowering you to better understand what corrective steps to undertake when alerted of extremely high or low blood glucose levels. Intake of 2 turmeric capsules daily kevin bacon julia roberts thrice a day. Gastric bypass surgery for weight loss in obese patients is very effective at reducing weight and has also recently been shown to cure type II diabetes. Find Endocrinologists in Birmingham. Besides the fact that an ulcer can be very painful it may be a sign of sickle cell diseae a condition that worsens over time. 4 diagnoses comprise Mesenteric Ischemia value of serum lactate difficult post-ERCP abdominal pain patient Pancreatitis BISAP score amylase vs lipase Diabetes Diet Plan Ice Cream Eating grapefruit has been found people lose weight which consequently can decrease risk for diabetes. Recipe by: for those who are not familiar with counting carbs for diabetics; who think sugar free means diabetic-friendly. En Diabetes tipo 2: Padecer de Diabetes mellitus tipo I insulino Despu Continue reading >>

Endocrine Reading 5

Endocrine Reading 5

Life for a person with diabetes mellitus means constant awareness of the illness--one or two insulin shots a day, frequent finger punctures to monitor blood glucose level, a restrictive diet, and concern over complications, which include loss of vision, leg ulcers, and kidney damage. The many symptoms of diabetes reflect disturbances in carbohydrate, protein, and fat metabolism. Diabetes in Latin means increased urine output, and mellitus means honey, referring to urine's sugar content. Lack of insulin decreases movement of glucose into skeletal muscle and adipose cells, inhibiting glycogen formation. As a result, blood sugar concentration rises (hyperglycemia). When blood sugar reaches a certain level, the kidneys begin to excrete the excess, and glucose appears in the urine (glycosuria). The osmotic pressure of water follows the glucose by osmosis, causing excess urinary water loss. As a result, the person becomes dehydrated and very thirsty. Diabetes mellitus decreased protein synthesis, causing tissues to waste away as glucose-starved cells use protein as an energy source. Weight falls and wounds cannot heal. Fatty acids accumulate in the blood as a result of decreased fat synthesis and storage. Ketone bodies, a by-product of fat metabolism, also increase in the blood. They are excreted in the urine as sodium salts, and large quantities of water follow by osmosis, intensifying dehydration and lowering sodium concentration in the blood. Accumulation of ketones and loss of sodium ions lead to metablic acidosis, a condition that lowers the pH of body fluids. Acidosis and dehydration adversely affect brain neurons. Without treatment (insulin replacement), the person becomes disoriented and may enter a diabetic coma and die. There are two common forms of diabetes mellit Continue reading >>

Activity 5b: Tonic Water Hyper And Hypo

Activity 5b: Tonic Water Hyper And Hypo

Each student should receive two pieces of a high water-content vegetable such as eggplant, squash or beet. The vegetable pieces should be blotted dry with the paper towels and weighed. Honey (represents sugar) should be sprinkled onto one of the vegetable slices (the one without honey is the control sample). (Approximately 1/4 of a teaspoon of honey with a slice of zucchini squash which is one inch across works well!) The students should record what they observe at the beginning (time = 0), and then at five minute intervals for 1520 minutes. The honey will extract the water from the vegetable; the water will accumulate on the surface of the vegetable and be readily visible. This demonstrates how the high sugar content of blood in a diabetic extracts water from the bodys tissues, resulting in frequent urination and dehydration. The vegetable can be toweled off, so that students can further observe the water that was being extracted from the vegetable and weighed again. Point out that the sugar has the same drying effect that salt has. Students will make a graph to determine the rate of water loss in the zucchini. In this part of the activity, students will quantify the rate of osmosis in zucchini or other high-water content vegetable. Students will place one piece of zucchini in distilled water and another piece of zucchini in concentrated sugar water. They will observe the change in mass over time and determine the rate of osmosis in both vegetable samples. They will make a graph of their data and draw conclusions about their observations. The rate of osmosis between Part I and Part II can be compared. Observe the effect of honey placed on the vegetable Relate their observations to what happens to body cells exposed to high concentrations of blood glucose Continue reading >>

Diabetes Mellitus And Polyuria

Diabetes Mellitus And Polyuria

Diabetes comes from the Greek word which means “siphon”. There are two distinct disorders that share the first name diabetes: diabetes mellitus and diabetes insipidus. This is because both disorders cause polyuria, or excessive urine output. Diabetes insipidus is a disorder of urine concentration which we will discuss in spring quarter. Diabetes mellitus is a disorder of blood glucose regulation, which results from a deficiency in the action of the hormone insulin. This may be due to autoimmune destruction of the insulin-secreting cells of the pancreas (type 1 diabetes mellitus) or it may result from a problem in the responsiveness of tissues to insulin, known as insulin resitance (type 2 diabetes mellitus). With either disorder, the result is hyperglycemia, or high levels of glucose in the plasma. How does hyperglycemia cause excessive urine production? To answer this, we need to understand a little bit about how the kidney works. Each kidney contains about a million functional units called nephrons (blue structure in the figure). The first step in the production of urine is a process called filtration (green arrow). In filtration, there is bulk flow of water and small molecules from the plasma into Bowman’s capsule (the first part of the nephron). Because of the nonspecific nature of filtration, useful small molecules such as glucose, amino acids, and certain ions end up in the forming urine, which flows into the kidney tubules. To prevent the loss of these useful substances from the body, the cells lining the kidney tubules use epithelial transport to transfer these substances out of the forming urine and back into the extracellular fluid. This process is known as reabsorption (purple arrows). Under normal circumstances, 100% of the glucose that is filtered is Continue reading >>

The Lens In Diabetes.

The Lens In Diabetes.

Bron AJ(1), Sparrow J, Brown NA, Harding JJ, Blakytny R. (1)Department of Ophthalmology, University of Oxford, UK. This paper reviews the changes which occur in the human lens in diabetes. Theyinclude refractive changes and cataract and age-related increases in thickness,curvatures, light scattering, autofluorescence and yellowing. The incidence ofcataract is greatly increased over the age of 50 years, slightly more so inwomen, compared with non-diabetics. Experimental models of sugar cataract providesome evidence for the mechanism of the uncommon, but morphologically distinct,juvenile form of human diabetic cataract, where an osmotic mechanism due to sugaralcohol accumulation has been thoroughly studied in diabetic or galactose-fedrats. The discrepancy between the ready accumulation of sugar alcohol in the lensin model systems and the very slow kinetics of aldose reductase (AR) has not beensatisfactorily explained and suggests that the mechanism of polyol formation isnot yet fully understood in mammalian systems. The activity of AR in the humanlens lies mainly in the epithelium and there appears to be a marginal expectationthat sufficient sorbitol accumulates in cortical lens fibres to explain the lens swelling and cataract on an osmotic basis. This is even more so in the cataracts of adult diabetics, which resemble those of age-related non-diabetic cataracts inappearance. The very low levels of sorbitol in adult diabetic lenses make anosmotic mechanism for the increased risk of cataract even less likely. Othermechanisms, including glycation and oxidative stress, are discussed. Theoccurrence of cataract is a predictor for increased mortality in the diabetic. Continue reading >>

Osmotic Diuresis And Diabetes

Osmotic Diuresis And Diabetes

Osmotic diuresis occurs when substances in the blood accumulate in the tubules of the kidney, reducing reabsorption of water in the kidneys, thereby increasing urine output. Osmosis refers to the movement of fluids through porous membranes. The fluid, often water, tends to move from a more dilute concentration on one side of the membrane to a less dilute concentration on the other side, effectively equalizing concentrations on both sides of the membrane. Diuresis is an increase in the discharge of urine. Why it Happens The primary cause of osmotic diuresis is elevated blood glucose (hyperglycemia) which is sometimes the result of poorly controlled diabetes. When there is excess glucose in the blood, and it passes through the kidneys for filtering, the excess glucose accumulates in the tubules within the kidneys. Once there, it blocks the reabsorption of water, leading to an increased concentration of water in the bloodstream. The kidneys then act to remove the excess water, causing increased urine production and increased frequency in urination. Patients who suffer from diuresis stand to lose significant amounts of fluid as well as essential mineral salts. Symptoms of dehydration may be present. Another cause of osmotic diuresis is taking certain medications (e.g. Mannitol.) How Osmotic Diuresis is Diagnosed There are no specific tests for osmotic diuresis, other than a urinalysis to look for changes in the urine. Diagnosis of osmotic diuresis is done by a physician taking into consideration all symptoms. If the patient is diabetic and producing larger than normal amounts of urine, then osmotic diuresis would be considered. Symptoms of Osmotic Diuresis The primary symptoms of osmotic diuresis are an increase in the quantity of urine and the frequency of passing urine. S Continue reading >>

Why Does Diabetes Cause Excessive Thirst?

Why Does Diabetes Cause Excessive Thirst?

7 0 We’ve written before about the signs and symptoms of diabetes. While there are a lot of sources about what symptoms diabetes causes, and even some good information about why they’re bad for you, what you don’t often get are the “whys”. And while the “whys” aren’t necessarily critical for your long-term health, they can help you to understand what’s going on with your body and why it acts the way it does. That, in turn, can help with acceptance and understanding of how to better treat the symptoms, which in turn can help you stay on a good diabetes management regimen. In short, you don’t NEED to know why diabetes causes excessive thirst, but knowing the mechanism behind it can make your blood glucose control regimen make more sense and help you stick to it. So why DOES diabetes cause thirst? First, we’d like to start by saying that excessive thirst is not a good indicator of diabetes. For many people, the symptom creeps up so slowly that it’s almost impossible to determine if your thirst has noticeably increased (unless you keep a spreadsheet of how much water you drink, in which case you also probably get tested pretty regularly anyway). It’s also a common enough symptom that a sudden increase in thirst can mean almost anything. Some conditions that cause thirst increases include allergies, the flu, the common cold, almost anything that causes a fever, and dehydration caused by vomiting or diarrhea. So while excessive thirst is one of those diabetes symptoms that happens, and needs to be addressed, it’s not always a great sign that you should immediately go out and get an A1C test. Why does diabetes cause thirst? Excessive thirst, when linked to another condition as a symptom or comorbidity, is called polydipsia. It’s usually one of the Continue reading >>

Diabetes Mellitus (dm)

Diabetes Mellitus (dm)

Years of poorly controlled hyperglycemia lead to multiple, primarily vascular complications that affect small vessels (microvascular), large vessels (macrovascular), or both. (For additional detail, see Complications of Diabetes Mellitus.) Microvascular disease underlies 3 common and devastating manifestations of diabetes mellitus: Microvascular disease may also impair skin healing, so that even minor breaks in skin integrity can develop into deeper ulcers and easily become infected, particularly in the lower extremities. Intensive control of plasma glucose can prevent or delay many of these complications but may not reverse them once established. Macrovascular disease involves atherosclerosis of large vessels, which can lead to Immune dysfunction is another major complication and develops from the direct effects of hyperglycemia on cellular immunity. Patients with diabetes mellitus are particularly susceptible to bacterial and fungal infections. Continue reading >>

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