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Can You Split Metformin?

Proper Use

Proper Use

Drug information provided by: Micromedex This medicine usually comes with a patient information insert. Read the information carefully and make sure you understand it before taking this medicine. If you have any questions, ask your doctor. Carefully follow the special meal plan your doctor gave you. This is a very important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment. Swallow the extended-release tablet whole with a full glass of water. Do not crush, break, or chew it. While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about. Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. You may notice improvement in your blood glucose control in 1 to 2 weeks, but the full effect of blood glucose control may take up to 2 to 3 months. Ask your doctor if you have any questions about this. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the Continue reading >>

Pill Splitting: When Is It Ok?

Pill Splitting: When Is It Ok?

Dr. Orrange is an Associate Professor of Clinical Medicine in the Division of Geriatric, Hospitalist and General Internal Medicine at the Keck School of Medicine of USC. If you take prescription drugs to treat a chronic illness, its possible to save more than 50% off cost of your medication by simply splitting your pills. Sadly, its not all that easy to know when pill splitting is all right. Not all pills can be split. However, many doctors and insurance companies are advising this strategy with an increasing number of medicines. (Its also worth noting that the American Medical Association, the American Pharmacists Association, and most pharmaceutical companies oppose pill-splitting.) Drugs that should usually not be split include capsules, chemotherapy drugs, birth control pills, seizure-related medications, and any pill that has a coating or other controlled- or extended-release feature. Be sure to check with your doctor prior to splitting any medication. Is it scored?Tablets that are scored can be easily split and have been evaluated by the FDA for safety. Invest in a pill splitter. Pill splitters are very inexpensive and carried by most pharmacies. If youre going to split a pill, spend the $5. Only split once. It is only recommended that you split pills in half, not any smaller. The dose per piece is too likely to be uneven and pills may shatter or crumble. Unequal halves. Even scored tablets can be difficult to split into two perfect halves, and medicine is sometimes distributed unevenly within a single tablet. Buy a pill splitter to help and dont split with a knife. Crumbs. Tablets that are round or too small may crumble easily or unevenly when split and that will affect the dose you are actually getting. Dont forget!Patients who are given a higher dose pill and Continue reading >>

When It's Safe To Split Pills

When It's Safe To Split Pills

It sounds simple enough: Cut your pills in half to cut your prescription costs in half. The do-it-yourself practice of pill splitting is one that many doctors and health plans support. It’s a way to counter rising drug prices and encourage people to take their medications if they’re likely to skip doses and refills because of high costs. And those who have trouble swallowing medicine might find a smaller pill easier to manage. How It Works Your doctor will prescribe a higher dose of medication, often double. (Sometimes the higher dose is the same price as the lower dose.) At home, you cut the pills in half and take one half each day, ending up with two doses for the price of one. But deep discounts aren’t guaranteed, so first ask your pharmacist what you’ll save, advises Barbara Young, Pharm.D., editor of consumer-medication information for the American Society of Health System Pharmacists in Bethesda, Md. Note that the Food and Drug Administration has called pill splitting a “risky practice” and doesn’t encourage it unless a drug’s package insert specifically says it has been approved for splitting. But our medical advisers say it’s safe if you follow the guidelines below. Four Smart Steps 1. Get your doctor (or pharmacist) to OK it first. According to an April 2015 poll by Consumer Reports Best Buy Drugs, 8 percent of consumers trying to save money on medications admitted to cutting their pills in half without a doctor’s or pharmacist’s approval. Many drugs—notably most cholesterol-lowering statins, and those to treat high blood pressure and depression—can be split without losing effectiveness or causing a negative health impact, but it can be dangerous for you to divide others. Your doctor may have other reasons to warn you about splitting p Continue reading >>

What Is Metformin?

What Is Metformin?

MORE Metformin is a prescription drug used primarily in the treatment of Type II diabetes. It can be used on its own or combined with other medications. In the United States, it is sold under the brand names Fortamet, Glucophage, Glumetza and Riomet. "Metformin is very often prescribed as the first step in a diabetic's regime," said Ken Sternfeld, a New York-based pharmacist. How it works "When you're diabetic you lose the ability to use the insulin you need to offset the food," Sternfeld explained. "If you eat a carb or sugar that can't be metabolized or offset by the insulin you produce, your sugar levels will be higher. Metformin and drugs in that category will help your body better metabolize that food so that insulin levels will be able to stay more in line." Metformin aims to decrease glucose production in the liver, consequently lowering the levels of glucose in the bloodstream. It also changes the way that your blood cells react to insulin. "It makes them more sensitive to insulin," said Dr. Stephen Neabore, a primary care doctor at the Barnard Medical Center in Washington, D.C. "It makes the same amount of insulin work better. It transports the insulin to the cells in a more effective way." Metformin may have a preventive health role, as well. New research presented at the American Diabetes Association 2017 Scientific Sessions showed that long-term use of metformin is particularly useful in preventing the onset of type II diabetes in women who have suffered from gestational diabetes. Because metformin changes the way the body uses insulin, it is not used to treat Type I diabetes, a condition in which the body does not produce insulin at all. Metformin & PCOS Metformin is sometimes prescribed to treat polycystic ovarian syndrome (PCOS), according to Neabore. "I Continue reading >>

Metformin, Oral Tablet

Metformin, Oral Tablet

Metformin oral tablet is available as both a generic and brand-name drug. Brand names: Glucophage, Glucophage XR, Fortamet, and Glumetza. Metformin is also available as an oral solution but only in the brand-name drug Riomet. Metformin is used to treat high blood sugar levels caused by type 2 diabetes. FDA warning: Lactic acidosis warning This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects. Lactic acidosis is a rare but serious side effect of this drug. In this condition, lactic acid builds up in your blood. This is a medical emergency that requires treatment in the hospital. Lactic acidosis is fatal in about half of people who develop it. You should stop taking this drug and call your doctor right away or go to the emergency room if you have signs of lactic acidosis. Symptoms include tiredness, weakness, unusual muscle pain, trouble breathing, unusual sleepiness, stomach pains, nausea (or vomiting), dizziness (or lightheadedness), and slow or irregular heart rate. Alcohol use warning: You shouldn’t drink alcohol while taking this drug. Alcohol can affect your blood sugar levels unpredictably and increase your risk of lactic acidosis. Kidney problems warning: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug. Liver problems warning: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems. Metformin oral tablet is a prescription drug that’s available as the brand name drugs Glucophage, Glucophage XR, Fortamet, and Glumetza. Glucophage is an immediate-release tablet. All of the other brands are extended-r Continue reading >>

Tag : Can You Split Metformin Xr Get Generic Cheap Glucophage (metformin) Without A Prescription Online.

Tag : Can You Split Metformin Xr Get Generic Cheap Glucophage (metformin) Without A Prescription Online.

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Diabetes Drugs: Metformin

Diabetes Drugs: Metformin

Editor’s Note: This is the second post in our miniseries about diabetes drugs. Tune in on August 21 for the next installment. Metformin (brand names Glucophage, Glucophage XR, Riomet, Fortamet, Glumetza) is a member of a class of medicines known as biguanides. This type of medicine was first introduced into clinical practice in the 1950’s with a drug called phenformin. Unfortunately, phenformin was found to be associated with lactic acidosis, a serious and often fatal condition, and was removed from the U.S. market in 1977. This situation most likely slowed the approval of metformin, which was not used in the U.S. until 1995. (By comparison, metformin has been used in Europe since the 1960’s.) The U.S. Food and Drug Administration (FDA) required large safety studies of metformin, the results of which demonstrated that the development of lactic acidosis as a result of metformin therapy is very rare. (A finding that has been confirmed in many other clinical trials to date.) Of note, the FDA officer involved in removing phenformin from the market recently wrote an article highlighting the safety of metformin. Metformin works primarily by decreasing the amount of glucose made by the liver. It does this by activating a protein known as AMP-activated protein kinase, or AMPK. This protein acts much like an “energy sensor,” setting off cellular activities that result in glucose storage, enhanced entry of glucose into cells, and decreased creation of fatty acids and cholesterol. A secondary effect of the enhanced entry of glucose into cells is improved glucose uptake and increased storage of glycogen (a form of glucose) by the muscles. Additionally, the decrease in fatty acid levels brought about by metformin may indirectly improve insulin resistance and beta cell func Continue reading >>

What Are The Possible Side Effects Of Glyburide And Metformin (glucovance)?

What Are The Possible Side Effects Of Glyburide And Metformin (glucovance)?

GLUCOVANCE® (glyburide and metformin hcl) Tablets, 1.25 mg/250 mg, 2.5 mg/500 mg, 5 mg/500 mg DESCRIPTION GLUCOVANCE® (Glyburide and Metformin HCl) Tablets contain 2 oral antihyperglycemic drugs used in the management of type 2 diabetes, glyburide and metformin hydrochloride. Glyburide is an oral antihyperglycemic drug of the sulfonylurea class. The chemical name for glyburide is 1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclo-hexylurea. Glyburide is a white to off-white crystalline compound with a molecular formula of C23H28ClN3O5S and a molecular weight of 494.01. The glyburide used in GLUCOVANCE has a particle size distribution of 25% undersize value not more than 6 μm, 50% undersize value not more than 7 to 10 μm, and 75% undersize value not more than 21 μm. The structural formula is represented below. Metformin hydrochloride is an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride (N,N-dimethylimidodicarbonimidic diamide monohydrochloride) is not chemically or pharmacologically related to sulfonylureas, thiazolidinediones, or α-glucosidase inhibitors. It is a white to off-white crystalline compound with a molecular formula of C4H12ClN5 (monohydrochloride) and a molecular weight of 165.63. Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. The structural formula is as shown: GLUCOVANCE is available for oral administration in tablets containing 1.25 mg glyburide with 250 mg metformin hydrochloride, 2.5 mg glyburide with 500 mg metformin hydrochloride, and 5 mg glyburide with 500 mg metformin hydrochloride. In addition, each tablet contains the f Continue reading >>

Medicine Information - Kaiser Permanente

Medicine Information - Kaiser Permanente

Brand name(s): Fortamet, Glucophage XR, Glumetza Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. For some conditions, your doctor may tell you to stop taking this medication for a short time. Ask your doctor or pharmacist for more details.Stop taking this medication and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea. Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.Metformin may be used with lifest Continue reading >>

Diabetes - Metformin Off Market Mbaudc.es

Diabetes - Metformin Off Market Mbaudc.es

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Some Advice On Metformin Dose

Some Advice On Metformin Dose

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Could someone give me advice. I am three months in from diagnosis. I started at fasting 12 and was spiking to 18 after some meals I am now after a medium low carb diet 80-90 carbs and 1 500mg metformin each evening with dinner down to 6s and 7s at night before bed and 7s and 8s in the morning fasting although I can spike up to 10 after lunch. Obviously this is getting better but not quite there. My question is I have my annual check (after three months!) with the doc in a couple of weeks. Obviously I want to talk about how to get my readings down another point really. I find I cannot each much breakfast and lunch as I spike but OK to eat dinner and then I take my metformin tablet with dinner in the evening that obviously must make some difference as I do not spike then. I know that they will probably want to up my dose of metformin to 2 x 500mg to bring the spikes down and hopefully my food tolerance in the first half of the day. My question is (because I am sure the dr will not know - they are not particularly expert it seems at my surgery) Do you take the metformin one on the morning and one in the evening to even out the long term slow release bit of the tablet. I am hoping the answer will be yes so that the first half of the day becomes slightly easier for me. I cannot eat anything but a slice of apple or 1 rich tea biscuit until about midday this has actually the same effect as if I had ate nothing, I stay about whatever the fasting number is in the morning even if I eat nothing. If i try to eat anything else I will go to 10 and above and cereal, porridge, fruit, toast whatever sends me high. By lunchtime I can eat something with about 15-20 carb Continue reading >>

Splitting Diabetic Medicine Is It Ok | Diabetic Connect

Splitting Diabetic Medicine Is It Ok | Diabetic Connect

no way a good idea .i take metforin my instructions say not to cut crush orchew these pills.not if you get sick but i say they would'nt work as well. If you google Juvaderm it talks about wrinkles. She may be taking Januvia or Janumet . Janumet has metformin in it. and yes you can split Januvia with no side effects For my self, I had taken Metformin on a Wednesday evening, and by the next morning I was so sick, nauseated, my stomach was having sharp pains, I was feeling dizzy, head-aching, and I couldn't function, so I called my doctor who happen to be out of town, but I wouldn't let the nurse get off the phone till she told me she would call the doctor. By afternoon, the doctor changed my script to Onglyza and I haven't had any problems since. And I have known that I am diabetic for one month now. So I have a lot to learn still. So I can relate with your mom on Metformin. I have been on Metformin 500 for quite a while, have never had any side effects from it. However, when my numbers still needed to come down, my dr. told me to take 2 of them twice a day. (I had been taking one twice a day). That was way too much, my heart was racing and I felt awful til it wore off. When I told him that it dropped my blood sugar too low, he said I would have to adjust it til I found the right dosage that helped my blood sugar levels, but was also not too much at the same time, and if I needed to split one in half, that was ok. But still check with your mom's dr. Since she has Alzheimer's also, she may on other meds that may interfere with her diabetes meds. She is lucky to have you to help care for her, that is a heavy load to carry. God bless you I was put on glipizide this week because I'm allergic to metformin. The first time I took it I took a full pill and it dropped me to fast Continue reading >>

Order Prescription Medications Metformin 500mg Tablet Price

Order Prescription Medications Metformin 500mg Tablet Price

Pills-only one or more blister packs containing 10 pills each. All teams under 60 pills are shipped in 1 package. Large orders can be split into two packs and come in 2 separate envelopes. Metformin can be used to gain control the level of blood glucose in people with type II diabetes. It is sometimes used in combination with insulin or other medications, but this Medicine is Not for treating type 1 diabetes type. over the counter metformin alternatives, metformin otc alternative, glimepiride 1mg metformin 500mg price, metformin drug prices, order metformin online, buy metformin without doctor, metformin hydrochloride for sale, where to buy metformin 1000mg, how to get metformin for weight loss, non prescription metformin You should also have in mind some possible delays in customs we are not responsible for. Thus why some parcels may arrive a bit later or earlier than expected. Delivery time can also depend on the country of destination. National and religious holidays may delay the arrival of a parcel. Your order will soon be completed discreetly for your privacy and security. Read this information carefully before you start taking this medicine and each time you refill your prescription. There may be new information. This advice can not replace doctor's recommendations. Ask your doctor or pharmacist if You do not know the number of this advice, or you would like to learn more about this medicine. Cells are more able to eliminate sugar in the blood. Viagra Metformin also slows the absorption of Sugars from the intestines. Metformin reduces blood sugar levels after eating. Our customers health and the speedy delivery is our Priority. Therefore, we keep the strictest standards of security and confidentiality to keep Your personal information, as well as the only e-Comm Continue reading >>

Metformin Overview

Metformin Overview

Metformin is a prescription medication used to treat type 2 diabetes. Metformin belongs to a group of drugs called biguanides, which work by helping your body respond better to the insulin it makes naturally, decreasing the amount of sugar your liver makes, and decreasing the amount of sugar your intestines absorb. This medication comes in tablet, extended-release tablet, and liquid forms. It is taken up to 3 times daily, depending on which form you are taking. Swallow extended-release tablets whole. Common side effects of metformin include diarrhea, nausea, and upset stomach. Metformin is a prescription medication used to treat type 2 diabetes. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Metformin may be found in some form under the following brand names: Serious side effects have been reported including: Lactic Acidosis. In rare cases, metformin can cause a serious side effect called lactic acidosis. This is caused by a buildup of lactic acid in your blood. This build-up can cause serious damage. Lactic acidosis caused by metformin is rare and has occurred mostly in people whose kidneys were not working normally. Lactic acidosis has been reported in about one in 33,000 patients taking metformin over the course of a year. Although rare, if lactic acidosis does occur, it can be fatal in up to half the people who develop it. It is also important for your liver to be working normally when you take metformin. Your liver helps remove lactic acid from your blood. Make sure you tell your doctor before you use metformin if you have kidney or liver problems. You should also stop using metformin and call your doctor right away if you have signs of lactic acidosis. Lactic acidosis is a medical emergency that must be treate Continue reading >>

Can Metformin Be Cut?

Can Metformin Be Cut?

I have seen a variety of opposite answers for this on a google search. I have metformin tablets 500mg. I do not believe that they are extended release as the doctor did not write the prescription that way. I would like to split one in half to take half at lunch and half at dinner times. Can these be cut? I think you can cut them if they are not the extended version. The extended version should say EX on the prescription bottle. Why do you want to cut them? If taking it once a day doesn't seem to work you may want to ask doctor to increase your dose. It took me 3 changes before it gave me the numbers I wanted. I now take it 3 times a day. I have seen a variety of opposite answers for this on a google search. I have metformin tablets 500mg. I do not believe that they are extended release as the doctor did not write the prescription that way. I would like to split one in half to take half at lunch and half at dinner times. Can these be cut? There's nothing to stop you from cutting them in half, however Metformins action is such that taking one 500mg pill per day has the same effect as cutting it in half and taking both halfs in the same day. Metformin takes some time to build up in the body to have an effect and depending on your specific needs the doctor may be increasing the dosage in the future. I do ask tho, why the desire to split the dose? 500 mg did nothing for me. I now take 2550 mg. My doctor told me the same thing that it is the total amount you take a day. I asked to be switched to the ER version because I heard the delivery may be better but he said the max for the extended would be 2000 and I take 2550 so it would be a reduction in dose. So I didn't switch. The extended release version CANNOT be cut. MEDS... 1000 mg ER met, 2000IU vitamin D3, multi vitamins, Continue reading >>

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