Can I Have Grapefruit While Taking Metformin?
Many medications, such as statins and some antihistamines, have a negative interaction with grapefruit. Metformin is used in treatment of type 2 diabetes. Does having grapefruit while taking metformin lead to adverse side effects? There’s limited research, but here’s what you need to know. Metformin is a drug that’s prescribed to treat type 2 diabetes. People with type 2 diabetes can’t use insulin normally. This means they can’t control the amount of sugar in their blood. Metformin helps people with type 2 diabetes control the level of sugar in their blood in several ways, including: decreasing the amount of sugar your body absorbs from food decreasing the amount of sugar produced by your liver increasing your body’s response to the insulin that it makes naturally Metformin can rarely cause a very serious and life-threatening condition called lactic acidosis. People with liver, kidney, or heart problems should avoid taking metformin. There are more than 85 drugs that are known to interact with grapefruit. Of these drugs, 43 of them can lead to serious adverse effects. All forms of grapefruit — including freshly squeezed juice, frozen concentrate, and the whole fruit — can lead to drug interaction. Some of the chemicals found in grapefruit can bind to and inactivate an enzyme in your body that’s found in your intestines and liver. This enzyme helps break down the medication you take. Normally when you take a drug orally, it’s broken down slightly by enzymes before it reaches your bloodstream. This means that you receive a little less of the drug in your bloodstream than the amount you initially consumed. But when the enzyme is inhibited — as it is when it interacts with the chemicals in grapefruit — there’s a dramatically larger amount of the dr Continue reading >>
What Are The Effects Of Grapefruit On Diabetes
Although grapefruit is a great source of vitamin C, many diabetics should avoid this fruit because of its well known interactions with many types of medications. Check with your doctor or pharmacist to see whether you can safely include grapefruit in your diet. If you are not on any medications, you can eat grapefruit without any problems. Keep in mind that, as with any fruit, too much can raise your blood sugar levels beyond your target range. The amount of carbohydrates found in a whole small or half of a large grapefruit is similar to the amount of carbohydrates found in a small apple, pear or two kiwifruits. Carbohydrates from fruits, just like the carbohydrates from sugar or flours, can raise your blood sugar levels. With about 15 grams of carbohydrates per serving, fruits such as grapefruit can usually be included in your diabetes meal plan. Monitor your blood sugar levels at regular intervals to ensure that your diet helps you keep them under control. Avoid grapefruit juice, because it doesn't contain any fiber and provides more carbohydrates per serving, with about 24 grams per cup. Glycemic Index Grapefruit has a glycemic index of 25, which makes it a safer carbohydrate option compared to high glycemic index choices like white rice, bread and potatoes. A glycemic index value below 55 is considered low and is best for diabetics. In other words, even if you eat the same amount of carbohydrates by eating either half of a large grapefruit or 1/3 cup of cooked white rice, your blood sugar levels will not increase as much with grapefruit compared to white rice because of their different glycemic index values. Medication Interactions The main problem with grapefruit for people with diabetes is its interaction with many drugs used to control blood pressure, blood chole Continue reading >>
Type Ii Diabetes: 6 Fruits To Help Control Your Blood Sugar
Type II Diabetes: 6 Fruits to Help Control Your Blood Sugar Controlling your diabetes could be as easy as losing weight. There are many things that you can do to control you blood sugar and increasing your intake of certain fruits is one of them. Natural sugar is easier to break down than processed or man-made sugar. This is why adding fruit, a great source for natural sugar, to your diet in moderation could prevent your body from building an insulin intolerance. Here are our favorite fruits to add to your diet if you are looking to naturally control your blood sugar, or decrease the amount of insulin that you use each day. 1. Avocado Avocado is thought by many to be a vegetable. On the contrary, it is actually a fruit. This fruit is high in monounsaturated fats which are one of the healthy fats that you should ingest on a regular basis. These fruits also improve heart health. They have a very low percentage of low-quality carbohydrates and can improve the sensitivity you have to your insulin. This means that simply snacking on avocado, eating guacamole, or adding it to a sandwich could decrease the amount of insulin that you have to take. 2. Grapefruits Grapefruits are a great source of chromium. Recent studies have shown chromium to significantly lower blood sugar levels. A grapefruit with breakfast can help break down the dietary sugars that are in your cereal as well. It also contains a very low amount of carbohydrates but most of these carbohydrates are considered healthy fiber so they won’t cause a serious increase in blood sugar. 3. Pineapples Pineapple does not prevent blood sugar spikes. However, it has a low glycemic index, which means that it raises your blood sugar slower and does not cause rapid spikes. This means that when your blood sugar starts low, it Continue reading >>
Grapefruit And Diet Of The Type 2 Diabetes
Grapefruit and Diet of the Type 2 Diabetes We would like to provide more We would like to provide more option on the fruit for patients of the type 2 diabetes, and were taken notice of such grapefruit where producing area come from China, it has effect of reduce blood glucose in saga.[br]Grapefruit, fructification of [italic]Citrus grandis [/italic](L.) Osbeels. It is a fruit. Grapefruit, aqua raw contain Protein, lipid, Carbohydrate, various Mineral, and various Vitamins, and various Amino acids. It has enough nutritional value.[br]Its major chemical ingredients contain Glycosides: Hesperidin, Poncirin, Naringin, Neohesperidin, Tangeretin-4-Glucoside-7- Neohesperidin. The average of content of glucose was 14.98mmol/L via our test.[br]Ten early patients of type 2 diabetes that the range of normal in a fasting plasma, aged 45 to 55 years, volunteered for the experiment. Using a oneself-control method, to administer grapefruit and orange juice as a drug after eat respectively, follow, blood glucose were determined per half-hour, one hour and two hours.[br]The peak value of range of blood glucose is change from 12.6mmol/L to 13.9mmol/L when they eat the orange juice for 100ml on two hours, but when eating grapefruit juice for 100ml change from 10 to 11.1mmol/L on one hour.[br]Crisp raw of grapefruit may contain a matter, this chemical have effect of that reduced blood glucose, and the effect was late breaking, but it was strong and fast. Grapefruit can be a [ldquo]substituting sweeteners[rdquo] that contain sugar and calories. This qualitative study is a part of studies only, deciding the chemical will be future research task. Present, we do not understand that all type of grapefruit whether may reduce blood glucose or not? And also do not understand which chemical induce Continue reading >>
Could Grapefruit Juice Protect Against Diabetes?
"Grapefruit juice 'could be the key to weight loss','' is the misleading headline in The Daily Telegraph. It reports on a study in which mice fed a combination of a high-fat diet and grapefruit juice still put on weight – albeit at a lower rate than mice fed a sugary drink. Their blood sugar levels and insulin sensitivity were also better regulated than mice that did not drink grapefruit juice. The mice were given either a high-fat diet or a low-fat diet in a range of experiments. Mice fed a high-fat diet and grapefruit juice had an 18% reduced rate of weight gain compared with mice given sugary water with the same number of calories as the grapefruit juice. They also had 13% lower fasting blood sugar levels. There was no effect on weight gain in mice fed a low-fat diet. Drinking grapefruit juice improved insulin sensitivity in mice, regardless of their diet (in people, reduced insulin sensitivity can be a sign of impending diabetes). Grapefruit juice lowered blood sugar as effectively as metformin, a drug widely used to treat people with type 2 diabetes. However, none of the mice actually had diabetes, so this research has little immediate relevance to humans with the condition. For the time being, people with diabetes should not swap their metformin for grapefruit juice on the basis of this study. Where did the story come from? The study was carried out by researchers from the University of California and was funded by the California Grapefruit Growers Cooperative, although it had no role in the study design, data collection, analysis or decision to publish. The study was published in the peer-reviewed science journal PLOS ONE. This is an open-access journal, so the study is freely available to all. Both the Mail Online and The Daily Telegraph’s headlines incorrec Continue reading >>
What Are The Effects Of Grapefruit On Diabetes?
Grapefruit provides significant amounts of vitamins A and C and is relatively low in calories and low on the glycemic index, making it a nutritious fruit choice for diabetics. Eating grapefruit may also help you better control your blood sugar levels, but if you take certain medications, you may be better off choosing a different fruit because of potential medication interactions. Video of the Day Half of a large grapefruit has 53 calories and 13.4 grams of carbohydrates, including 1.8 grams of fiber. If you control your blood sugar by counting carbohydrates, this counts as one carbohydrate serving. Diabetics can typically have between 45 to 75 grams of carbohydrate per meal, or three to five carbohydrate servings. The glycemic index estimates the effect of a food that contains carbohydrates on your blood sugar levels. Foods with a low glycemic index of less than 55 aren't likely to cause large increases in blood sugar levels, while those with a high glycemic index of 76 or more may cause spikes in your blood sugar levels after you eat them. Grapefruit has a low GI of 25, so it isn't likely to have a significant effect on your blood sugar as long as you watch your portion size. Eating half a grapefruit before each meal may help you control your blood sugar levels and lose a small amount of weight, according to a study published in the "Journal of Medicinal Food" in March 2006. The fresh grapefruit helped improve insulin resistance as well as insulin levels two hours after eating. Grapefruit juice was also beneficial for weight loss, but not for improving insulin resistance. Stick with fresh grapefruit instead of grapefruit juice, which is higher in both calories and carbohydrates. Each 8-ounce glass has 94 calories and 22.1 grams of carbohydrates. Check with your doctor Continue reading >>
Grapefruit As Diabetes Drug
Your mother may have known something all those years ago when she went on a grapefruit diet to lose weight. People have eaten the fruit and drunk the juice for decades in the hope of dropping weight, and claims that grapefruit contained “something” that burned fat have sold many a diet book. Now it seems there may be some basis for this enduring dietary craze. In fact, an active ingredient in grapefruit appears to lower glucose levels as effectively as a widely-prescribed diabetes drug. Researchers at the University of California, Berkeley decided to test the link between grapefruit juice and weight loss using a controlled experiment. Previous studies on grapefruit juice were not rigorous, tended to be small and produced contradictory results. A natural fruit drink lowered glucose levels as effectively as a prescription drug. What they found surprised them. Mice that ate a high fat diet gained less weight when they drank grapefruit juice compared to mice that drank water. And the juice-drinking mice had better levels of glucose, insulin, and triglycerides, a type of fat, compared to those that drank water. The results were so astonishing, “We even re-checked the calibration of our glucose sensors, and got the same results over and over again,” said Andreas Stahl, one of the researchers in a statement. Different groups of mice were fed a variety of liquids. The control group was fed water with a small amount of glucose and saccharin added. The other groups drank different concentrations of slightly sweetened grapefruit juice and water. The calories were kept equal for all the mice. Along with the liquids, mice ate a diet that was either 60 percent fat or 10 percent fat for 100 days. One group of mice was also given naringin, a bioactive compound found in grapefru Continue reading >>
Can Diabetics Eat Grapefruit
Lisa Rivera | October 10, 2017 | Fruits for Diabetes | No Comments Fruits are a great source of vitamin C and in particular grapefruits. However, as much as grapefruit is packed with essential nutrients in the body, as a diabetic and under medication you should ensure that you avoid eating this particular fruit without consulting with your doctor. Grapefruit has a negative reaction to most medication, on the other hand, if you are under no medication then you can eat grapefruit, just ensure you dont take too much of it since it can cause your blood sugar levels to increase. Grapefruit has 15 grams per serving of carbohydrate and it should b included as part of your meal. On a closer view, a whole small grapefruit contains a similar amount of carbohydrates as that found in a small apple or a pear. To be safe you have to ensure that you monitor your blood sugar levels every now and then just to ensure that you keep it under control. It is advised that you should avoid drinking grape juice since it has high carbohydrates per serving and has no fiber On a scale of 0-100 grapefruit has a glycemic index of 25. Anything below 55 is considered as a low glycemic index this being a clear indication that on eating grapefruits you have less to worry about a sharp increase in your blood sugar levels. In comparison to other sources of carbohydrates such as potatoes and bread, it is safe to eat grapefruits since it wont have an increase in blood sugar levels. The only drawback in including grapefruit as part of your diabetic diet is due to its interactions with most of the drugs used to control blood cholesterol, blood pressure or depression. The chemistry and biology behind this is the fact that both raw grapes and juice has a substance that affects the normal functioning of an enzy Continue reading >>
Can Grapefruit Juice Prevent Weight Gain, Increase Insulin Sensitivity?
Since the 1930’s, one fad diet after another has hit the scene touting grapefruit consumption as a way to shed those unwanted pounds. But according to new animal research from the University of California, Berkeley, there may be some science to back up these claims. (This is not the first time grapefruit consumption has been in the news: A 2012 study found that the fruit and its juice can dangerously interact with a wide variety of prescription drugs, including several likely to be taken by people with diabetes.) Previous studies on the weight-loss effects of grapefruit juice have been small or not well controlled, and the findings have been contradictory, according to Joseph Napoli, PhD, and Andreas Stahl, PhD, lead authors of the current research. In order to increase knowledge about the metabolic effects of grapefruit juice consumption, the scientists randomly divided mice into six groups. All of the groups were fed either a high-fat (60% fat) or a low-fat (10% fat) diet, and two were provided with no-pulp grapefruit juice diluted with water at different concentrations and sweetened slightly with saccharin to counteract the bitterness of the juice. A third group received water mixed with naringin, a compound in grapefruit juice that has been identified as a key factor in weight loss; a fourth group was provided with the diabetes medicine metformin mixed into water; and a fifth group received metformin mixed into sweetened grapefruit juice. A control group of mice was fed a high-fat diet and given water with glucose and saccharin added to match the calorie and artificial sweetener content of the grapefruit juice mixtures. For 100 days, the mice maintained the study diets and had their metabolic health measured. At the end of the study period, the researchers found t Continue reading >>
Just Found This About Grapefruit & Water Type 2 Diabetics
Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Just Found this about Grapefruit & Water Type 2 Diabetics The trouble with any food studies is you do not know what else the people are eating. You can not live on grapefruit alone. If I was eating grapefruit and not eating a whole bunch more of food Id lose weight and Id reduce my glucose readings. I hear lots of us saying Ive cut my bs reading because Ive cut my carbs. In reality I would have expected this. If you do not put the carbs in then were would the glucose come from if you do not increase your proteins. Fats do not produce glucose. Its bound to be lower. The real test is if we raise our carbs long term does the glucose reading also rise? Ive seen plenty of people reduce their blood sugars to become non diabetes but how many of those are back to the eat well plate 180g carbs per day or have they just remained low carb eaters? Its interesting findings are worth publishing ( IMHO) There was also a significant reduction in 2-hour post-glucose insulin level in the grapefruit group compared with placebo. Half of a fresh grapefruit eaten before meals was associated with significant weight loss. In metabolic syndrome patients the effect was also seen with grapefruit products. Insulin resistance was improved with fresh grapefruit. I am not doing any Metformin but lots of exercise & good diet. I am going to add this to my diet. For folks who are taking drugs like statins, this, I believe may be off limits. So check with your doctor before starting to add grapefruit I'm so sorry but few to no healthcare professional would read further than the abstract of that article, and it certainly wouldn't be used within evidence based practice - except maybe as Continue reading >>
Grapefruit And Type 2 Diabetes
You probably think of grapefruit as just a tasty part of breakfast right? It's that pink to ruby red fruit that you sprinkle sugar on and then have a heck of a time getting out of its skin without squirting yourself. Well actually it's a lot more than that. Grapesruit, and to some degree all citrus fruits , have a lot more qualities than just good taste. In the case of the grapefruit, it may in fact help prevent or control Type 2 Diabetes. Type 2 diabetes is the most common form of the disease and millions of Americans have been diagnosed with it. Millions of others have it or are at high risk and simply don't know it. Diabetes occurs when the body doesn't produce enough insulin or the cells in the body ignore the insulin in the body already. Insulin is essential in breaking down glucose and allowing that natural sugar to get out of the blood stream and into the cells. If glucose is allowed to build up in the blood, it can lead to complications including blindness, neuropathy, skin infections and even heart attack. It's almost endemic in this country and much of the blame can be placed on our Western diet and relatively sedentary lifestyle. So where does the grapefruit come in? How can this ordinary cousin of fruits like oranges and tangerines help control one of the country's nastiest diseases? Well according to a team of Canadian medical researchers the answer is the amount of naringenin found in the fruit. Naringenin is flavonoids that helps the liver burn fat after a meal rather than store it. Less fat equals less glucose. Less glucose means a lesser chance of developing Diabetes. In a test on two sets of mice who were given the same diet, the set that was administered a naringenin supplement fared much better than the ones without. While one set of mice became fat Continue reading >>
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Grapefruit Juice May Be As Effective As Diabetes Drugs
TIME Health For more, visit TIME Health. A new mice study suggests that grapefruit juice might be just as effective as the type 2 diabetes drug, metformin, at lowering blood glucose. The research, which was funded by the California Grapefruit Growers Cooperative, was published Wednesday in the journal PLOS ONE. Regarding the funding, study co-author Joseph Napoli, PhD, professor and chair of nutritional sciences and toxicology at the University of California, Berkeley, said this: “I understand the skepticism.” But the funders had nothing to do with the experiment, he says, besides providing some money and grapefruits. “We were very clear in telling them, you’re going to get the data we get,” Napoli says. “We can’t guarantee you’re going to like what you see. It might be nothing.” What they found was not nothing. The researchers fed different groups of mice a range of liquids: sweetened diluted grapefruit juice, sweetened water, and water that contained metformin, a diabetes drug. The mice who were fed a high-fat diet typical of the average American and drank the grapefruit juice lost 18% more weight than those drinking sweetened water, and they had a 13-17% drop in blood glucose levels and threefold decrease in insulin levels. (Mice on a low-fat diet had far less dramatic effects.) But one of the biggest findings was that mice drinking grapefruit juice had glucose-lowering effects that were just as potent as the mice who sipped on metformin. “It was very surprising,” says Napoli. You might have to drink a lot to get those prescription-level effects, however. The amount of grapefruit juice used in mice equates about four cups a day in people, the study says. But the researchers were so encouraged by the results that they plan to next look at if lowe Continue reading >>
Grapefruit And Type 2 Diabetes: Nutrition Facts And Benefits
As its appearance reflects, the grapefruit is actually thought to be a hybrid between a pomelo and a sweet orange. The beautiful pink-fleshed citrus fruit is a low calorie breakfast staple for many. But how, you may be wondering, can grapefruit fit into a healthy diet for those with diabetes? Well, grapefruit happens to be a relatively low carb fruit that fits perfectly into your menu. Most people do just fine with smaller amounts of the fruit (think half of a grapefruit), and its many nutritional benefits definitely shouldn’t go unrecognized. Read on for a thorough exploration of how this sweet-and-sour delight can help round out a healthy diabetic diet. Grapefruit Nutrition Facts Grapefruit is low in calories (30-4o per half grapefruit) and as already suggested it's relatively low in carbohydrates at 8-10 grams of carbohydrates per half grapefruit. That same half grapefruit also contains 1 to 1.5 grams of fiber. Half a grapefruit contains approximately 59% of your recommended daily amount (RDA) of vitamin C, 7% RDA copper and vitamin A, 5% RDA potassium, and 4% RDA biotin and vitamin B1. Grapefruit has a low glycemic index of just 25. When eating grapefruit, be sure to pair it with a protein or fat source such as nuts, cottage cheese, or yogurt. Eating fats and proteins with carbohydrate sources helps slow down the release of glucose into the bloodstream. Health Benefits of Grapefruit Vitamin C: This powerhouse antioxidant helps boost immunity, prevent colds, helps with tissue repair, and promotes heart health. Lycopene: Another antioxidant, found only in pink and red grapefruit (not white). It helps protect against cancer and tumor growth. Limonoids: Phytonutrients found in citrus fruits that help protect against cancer and may help lower cholesterol. Pectin: This Continue reading >>
Grapefruit Juice May Affect Insulin Resistance
Drinking grapefruit juice daily can lead to weight loss and help control blood glucose… Grapefruit juice is considered to be high in nutrients while remaining relatively low in calories when compared to other fruit juices. These diets often rely on daily low calorie commitment, which calls into question the true weight loss effect of grapefruit juice. Also, previous studies have shown mixed results. The purpose of this study was to determine the impact of using grapefruit juice while maintaining a diet that was high in fat which is typical of many Americans. These results would be compared to those given a low fat diet. The study was performed on mice. The mice were randomized into groups that were given a diluted grapefruit juice or water sweetened with glucose and saccharin. Grapefruit juice use was also compared to water sweetened with glucose and saccharin that contained metformin. Weight and blood glucose samples were collected three times per week. An insulin ELISA was used to monitor insulin concentrations. Results showed that mice fed the high fat diet receiving grapefruit juice weighed 18.4% less than the controls after 100 days (31.4+0.7g vs 38.5+2.8g, P<0.05). This group also saw fasting blood glucose that was 13% lower compared to controls (P<0.05). Fasting serum insulin levels were 72% lower compared to controls (P<0.05). Finally, triglycerides in the liver were reduced by 38% in this group compared to the control group. Those mice on the low fat diet saw a decrease in fasting insulin, but none of the other effects as seen in the high fat diet group. Grapefruit juice use compared favorably to those receiving metformin. Weight loss was seen in both groups with no statistically significant difference noted. Both groups also saw lowered fasting blood glucose Continue reading >>
Type 2 Diabetes Diet: The Best Foods To Prevent Or Manage The Disease
Healthy eating is one of the best ways to manage type 2 diabetes. This type of diabetes is strongly linked to excess weight, so calorie reduction and the right kind of diabetes diet can go a long way toward an improvement in overall health. Among the most important components of good nutrition when you have type 2 diabetes are meals with the right mix of carbohydrates, proteins, and fats to keep your blood sugar as normal as possible throughout the day. With these basic building blocks in place, make sure to seek out particular foods and beverages that can give you an extra edge in managing type 2 diabetes, says Beth Reardon, RD, an integrative nutritionist in private practice in Boston and a senior nutrition adviser for Caring.com. Here are some foods to reach for to help you manage your diabetes better. Eat Brown Rice and Other Fiber-Rich Foods White rice has long been known to have a negative effect on blood sugar. Like most "white" foods, it causes blood sugar spikes. A moderate amount of healthy whole grains, such as brown rice, and other fiber-rich foods instead of processed grains may reduce the risk of complications like diabetic neuropathy, which is nerve damage resulting from high blood sugar. Brown rice is packed with fiber, an important component for diabetes management. “Because fiber is not digested by the body, it does not affect blood sugar levels,” Reardon says. “This helps keep blood sugar levels steady and may prevent glucose spikes.” Another way to add fiber to your diet is with beans and other legumes. Research published in April 2012 in Nutrition Journal showed that beans and rice eaten together do not cause as drastic a blood sugar spike as rice alone. Also, a study published in October 2016 in the Journal of the Science of Food and Agricu Continue reading >>