diabetestalk.net

Can 1000mg Metformin Be Cut In Half

Xigduo Xr (dapagliflozin And Metformin Hcl Extended-release Tablets): Side Effects, Interactions, Warning, Dosage & Uses

Xigduo Xr (dapagliflozin And Metformin Hcl Extended-release Tablets): Side Effects, Interactions, Warning, Dosage & Uses

(dapagliflozin and metformin HCl) Extended-Release Tablets Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. The onset of metformin-associated lactic acidosis is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain. Metformin-associated lactic acidosis was characterized by elevated blood lactate levels ( > 5 mmol/Liter), anion gap acidosis (without evidence of ketonuria or ketonemia), an increased lactate/pyruvate ratio; and metformin plasma levels generally > 5 mcg/mL [see WARNINGS AND PRECAUTIONS ]. Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, and hepatic impairment. Steps to reduce the risk of and manage metformin-associated lactic acidosis in these high risk groups are provided in the full prescribing information [see DOSAGE AND ADMINISTRATION , CONTRAINDICATIONS , WARNINGS AND PRECAUTIONS , DRUG INTERACTIONS , and Use in Specific Populations ]. If metformin-associated lactic acidosis is suspected, immediately discontinue XIGDUO XR and institute general supportive measures in a hospital setting. Prompt hemodialysis is recommended [see WARNINGS AND PRECAUTIONS ]. XIGDUO XR (dapagliflozin and metformin HCl)extended-release tablets contain two oral antihyperglycemic medications usedin the management of type 2 diabetes : dapagliflozin and metforminhydrochloride. Dapagliflozin is described chemic Continue reading >>

Can Metformin 1000 Mg Be Cut In Half

Can Metformin 1000 Mg Be Cut In Half

If you are on 500mg of metformin can you split a 1000mg pill My dr just lowered my dosage from 1000mg to 500 mg. I was wondering if i could just cut the 1000mg in half and still get the 500mg dosage. Can I cut the metformin 1000 mg in half to take 500 mg Definitely not, if you need the 1000mg to control your blood sugar. If the dr didn't order 500 mg, then you can't cut it. If you google metformin discounts, you will Can Metformin Be Cut? - Diabetes buy viagra online Daily Can Metformin Be Cut? I would like to split one in half to take half at lunch and half at dinner times. Can these be cut? 1000 mg ER met, Can I cut Metformin HCL 500mg tablets in half if the dose is Can I cut Metformin HCL 500mg tablets in half if the dose is too high for me and it isn't used for diabetes? Can Metformin Pills Be Cut In Half And Taken? My script is in 500 mg. pills. I take 500 mg for breakfast and tried taking 1000 mg with dinner, Metformin; Can Metformin Pills Be Cut In Half And Taken? can I cut Metformin 500mg ER in half to viagra coupon take? | Yahoo Answers I am just starting and would prefer to start out at 250 mg release and you can cut those in half if that's the dose Metformin can cause Can Metformin 1000mg pill be cut into half and used as 500mg Question - Can Metformin 1000mg pill be cut into half and used as 500mg dosage?, Ask a General & Family Physician Cut Metaformin in half? - Diabetes Forum Combination of what? If it's regular metformin, it can be cut in half. If it's the extended release version, it can NOT be cut in half. If it's a combination of drugs Cutting a 500 mg Metformin pill in 1/2 - Type 2 Diabetes Cutting a 500 mg Metformin pill in 1/2. Metformin pill in half and split the dosage in 1-2 hour intervals with meals? We cut the 500 in half. Can metformin table Continue reading >>

Medicine Information - Kaiser Permanente

Medicine Information - Kaiser Permanente

Brand name(s): Fortamet, Glucophage XR, Glumetza Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. For some conditions, your doctor may tell you to stop taking this medication for a short time. Ask your doctor or pharmacist for more details.Stop taking this medication and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea. Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.Metformin may be used with lifest Continue reading >>

Can Metformin Be Cut?

Can Metformin Be Cut?

I have seen a variety of opposite answers for this on a google search. I have metformin tablets 500mg. I do not believe that they are extended release as the doctor did not write the prescription that way. I would like to split one in half to take half at lunch and half at dinner times. Can these be cut? I think you can cut them if they are not the extended version. The extended version should say EX on the prescription bottle. Why do you want to cut them? If taking it once a day doesn't seem to work you may want to ask doctor to increase your dose. It took me 3 changes before it gave me the numbers I wanted. I now take it 3 times a day. I have seen a variety of opposite answers for this on a google search. I have metformin tablets 500mg. I do not believe that they are extended release as the doctor did not write the prescription that way. I would like to split one in half to take half at lunch and half at dinner times. Can these be cut? There's nothing to stop you from cutting them in half, however Metformins action is such that taking one 500mg pill per day has the same effect as cutting it in half and taking both halfs in the same day. Metformin takes some time to build up in the body to have an effect and depending on your specific needs the doctor may be increasing the dosage in the future. I do ask tho, why the desire to split the dose? 500 mg did nothing for me. I now take 2550 mg. My doctor told me the same thing that it is the total amount you take a day. I asked to be switched to the ER version because I heard the delivery may be better but he said the max for the extended would be 2000 and I take 2550 so it would be a reduction in dose. So I didn't switch. The extended release version CANNOT be cut. MEDS... 1000 mg ER met, 2000IU vitamin D3, multi vitamins, Continue reading >>

Metformin Vs Metformin Er

Metformin Vs Metformin Er

I'm seeing quite a few posts on BBSes from people who are having problems with metformin because of side effects that could be eliminated if they were taking the extended release form of this drug. For some reason, many family doctors don't seem to be aware that there is a ER version of this drug that has such benefits. This is probably because metformin is a cheap generic and isn't promoted by herds of beautiful ex-cheerleaders turned drug company salespushers who "educate" doctors about far more expensive--and less effective--newer drugs. Here are the facts: Metformin (also sold under the brand name Glucophage) comes in a regular version which is taken at meal time, three times a day, and an extended release form (marketed as ER or XR) which is taken once a day. Almost always, when people report diarrhea or intense heartburn with metformin, they are taking regular version. I experienced the heartburn on the regular drug. It was very disturbing because the pain was localized over my heart and felt just like the description of a heart attack you read in articles. My doctor assured me it was coming from the metformin, but that didn't make it any easier to live with because I kept wondering how, if I were having a real heart attack, I'd know it wasn't a pain from the drug? The ER version releases the drug more slowly and this usually eliminates the gastrointestinal problems. The trade off with taking the ER form is that the amount of blood sugar lowering you see might be a bit less than with the regular form as the drug acts in a slower smoother fashion rather than hitting all at once. But if you can't take the regular at all drug because of the side effects, the slight weakening in effect is a reasonable trade off. Plus, you only have to remember to take one dose rather Continue reading >>

Diabetes Drugs: Metformin

Diabetes Drugs: Metformin

Editor’s Note: This is the second post in our miniseries about diabetes drugs. Tune in on August 21 for the next installment. Metformin (brand names Glucophage, Glucophage XR, Riomet, Fortamet, Glumetza) is a member of a class of medicines known as biguanides. This type of medicine was first introduced into clinical practice in the 1950’s with a drug called phenformin. Unfortunately, phenformin was found to be associated with lactic acidosis, a serious and often fatal condition, and was removed from the U.S. market in 1977. This situation most likely slowed the approval of metformin, which was not used in the U.S. until 1995. (By comparison, metformin has been used in Europe since the 1960’s.) The U.S. Food and Drug Administration (FDA) required large safety studies of metformin, the results of which demonstrated that the development of lactic acidosis as a result of metformin therapy is very rare. (A finding that has been confirmed in many other clinical trials to date.) Of note, the FDA officer involved in removing phenformin from the market recently wrote an article highlighting the safety of metformin. Metformin works primarily by decreasing the amount of glucose made by the liver. It does this by activating a protein known as AMP-activated protein kinase, or AMPK. This protein acts much like an “energy sensor,” setting off cellular activities that result in glucose storage, enhanced entry of glucose into cells, and decreased creation of fatty acids and cholesterol. A secondary effect of the enhanced entry of glucose into cells is improved glucose uptake and increased storage of glycogen (a form of glucose) by the muscles. Additionally, the decrease in fatty acid levels brought about by metformin may indirectly improve insulin resistance and beta cell func Continue reading >>

A Ci= Confidence Interval B Extended-release Metformin Was Clinically Similar To Immediate-release Metformin Based On The Pre-defined

A Ci= Confidence Interval B Extended-release Metformin Was Clinically Similar To Immediate-release Metformin Based On The Pre-defined

Page 1 of 22 Metformin Hydrochloride Extended-Release Tablets 500 mg and 1000 mg Rx only DESCRIPTION Metformin hydrochloride extended-release tablets contain an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride (N, N- dimethylimidodicarbonimidic diamide hydrochloride) is a member of the biguanide class of oral antihyperglycemics and is not chemically or pharmacologically related to any other class of oral antihyperglycemic agents. The empirical formula of metformin hydrochloride is C4H11N5•HCl and its molecular weight is 165.63. Its structural formula is: Metformin hydrochloride is a white to off-white crystalline powder that is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. Metformin hydrochloride extended-release tablets are designed for once-a-day oral administration and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the active ingredient metformin hydrochloride, each tablet contains the following inactive ingredients: ammonio methacrylate copolymer type A, ammonio methacrylate copolymer type B, colloidal silicone dioxide, crospovidone, dibutyl sebacate, hypromellose, magnesium stearate, microcrystalline cellulose and povidone. USP dissolution test for metformin hydrochloride extended-release tablet is pending. SYSTEM COMPONENTS AND PERFORMANCE Metformin hydrochloride extended-release tablet is designed for once-a-day oral administration using the swellable matrix coated with a permeable membrane technology. The tablet is similar in appearance to other film-coated oral administered tablets but it consists of a swellable active core formulation that is coated Continue reading >>

Can Januvia 100 Mg Be Cut In Half

Can Januvia 100 Mg Be Cut In Half

1 Answer - Posted in: januvia - Answer: No. They arent scored which means they should not be cut. Januvia pills are not scored. The literature that comes with Januvia states that they cannot be crushed, split or chewed, and must be swallowed whole, although it is not really specific about why. In general yes if you cut the pill in half but most drugs can lost part of the effect if you cut them and leave the other half for later. 11 Oct 2016 Januvia is not for people with Type 1 diabetes. This pill can be split with a pill cutter and taken in half doses with no reprecussions. Sometimes medication will be given lower doses if blood sugar levels regularly drop too low. Half doses might be a good solution to that problem. Because Januvia does not Medication Guide. JANUVIA (jah-NEW-vee-ah). (sitagliptin). Tablets. Read this Medication Guide carefully before you start taking JANUVIA and each time you get a refill. There may be new information. This information does not take the place of talking with your doctor about your medical condition or your treatment. DOSAGE AND ADMINISTRATION-----------------------. The recommended dose of JANUVIA is 100 mg once daily. JANUVIA can be taken with or without food. (2.1). Dosage . assessment of causality in 5% of patients treated with JANUVIA 100 mg daily and more commonly than .. terminal half-life (t1/2) was 12.4 hours. 30 Dec 2015 At home, you cut the pills in half and take one half each day, ending up with two doses for the price of one. Many drugsnotably most cholesterol-lowering statins, and those to treat high blood pressure and depressioncan be split without losing effectiveness or causing a negative health impact, but it 4 Dec 2016 Cutting the 100mg pills in half could indeed cut your medication bill, but theres a right way and Continue reading >>

Sr Metformin | Diabetes Forum The Global Diabetes Community

Sr Metformin | Diabetes Forum The Global Diabetes Community

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community When is the best time for you to take it with the least side affects. I have been advised to take mine in the middle of my evening meal, so around 6pm and i have just started on 1000mg. I'm only on my second day and im feeling pretty awful, should i split the tablet and go to 500mg or move it to a dif time in the day, or just put up with it ? All I can say is what I do .I was presribed 2x500mg and I take one during breakfast and one during the evening meal. This was how I was told to take it and it works fine for me. You must not split a SR tablet if you are having bad reactions to the 1000g pill try asking your GP if you can have the dose in 2 500g so that you can take 1 with breakfast and 1 with your evening meal. You must not split a SR tablet if you are having bad reactions to the 1000g pill try asking your GP if you can have the dose in 2 500g so that you can take 1 with breakfast and 1 with your evening meal. I did wonder about if it was acceptable to split the SR tablet or not as they may not have the same quantity of each ingredient in each half, but they have a split line on them for some reason. I have had enough of a hard time obtaining the SR tablets that im just going to put up with it, whats strange is that the side affects are different of that of the normal metformin. I also wonder if there mite be some die off or herx reaction of the yeast if my blood sugars are lowering. I won der if there is more than one mechanism for slow release medication. I take Metformin SR 500mg tabs, two morning, two evening, and the instructions are quite specific... they must not be split or chewed, and the tablets do not have a score line on them. But I a Continue reading >>

Diabex Xr Extended Release Tablets

Diabex Xr Extended Release Tablets

Brand Information Consumer medicine information (CMI) leaflet Please read this leaflet carefully before you start using Diabex XR Extended release tablets. Download CMI (PDF) Download large text CMI (PDF) What is in this leaflet This leaflet answers some common questions about Diabex XR. It does not contain all the available information. It does not take the place of talking to your doctor, pharmacist or diabetes educator. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Diabex XR against the benefits expected for you. If you have any concerns about taking this medicine, talk to your doctor, pharmacist or diabetes educator. Keep this leaflet with your medicine. You may need to read it again. What Diabex XR is used for Diabex XR is used to control blood glucose (sugar) in people with Type 2 diabetes mellitus, especially in those who are overweight. It is used when diet and exercise are not enough to control high levels of blood glucose. Diabex XR can be used alone, or in combination with other medicines for treating diabetes. TYPE 2 DIABETES MELLITUS Type 2 diabetes mellitus is also called non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes. Insulin is a hormone that enables body tissues to take up glucose from the blood and to use it for energy or fat storage for future use. People with Type 2 diabetes are unable to make enough insulin or their body does not respond properly to the insulin it does make. This causes a build-up of glucose in the blood (hyperglycaemia), which can lead to serious medical problems. Long-term hyperglycaemia can lead to heart disease, blindness, kidney damage, poor blood circulation and gangrene. Signs of hyperglycaemia may include: tiredness or lack of energy headache thirst passing Continue reading >>

Cutting A 500 Mg Metformin Pill In 1/2

Cutting A 500 Mg Metformin Pill In 1/2

Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. As some of you know my mom was having problems taking 500 mg tablets of Metformin. She is taking reg Met, not the extended version. At one point, about the a week ago, we decided to cut the pill in 1/2 and give her the first half with dinner and the second 1/2 one hour later. At night she woke up and told my sister that she was getting itchy all over. Usually, when you get itchy you are having an alergic reaction, usually a mild one. I didn't ask my sister but, I don't think mom was getting any blisters/pimples. I'm allergic to penicilen so I know the symtoms of an allergic reaction. I don't think my mom was having an allergic reaction(she has been on Met for 1 1/2 yrs), but the itching did concern me and it still puzzles me. This was a week ago and I remember my sister calling me about 1am in the morning, my sister said mom was getting some itching comming up from her legs and on her arms. I told her to give her some water and keep on eye on her breathing. If she couldn't breath call 911. .... 911 was not necessary. As you all know, or most who having been following my mom's story we got her handle the 500 mg pills whole by taking water with her meals. We don't dare break the pill in half anymore. Is it safe to cut a Reg. (not the extended version) Metformin pill in half and split the dosage in 1-2 hour intervals with meals? What do you guys attribute the itching to? What do you guys attribute the itching to? When DX, my doctor put me on 250MG's twice a day. We cut the 500 in half. I usally take it with meals in the morning and at night. The dosage worked very well for me getting my reading Continue reading >>

Can Metformin Xr Be Cut In Half 153507

Can Metformin Xr Be Cut In Half 153507

Can You Cut Or Split Metformin ER In Half? PharmacistAnswers Due to this release mechanism, Glucophage XR can not be cut or split. . Glumetza ER uses a mechanism known as gastro-retentive technology (also known as 39;Modified Release 39;). The tablets are designed to remain in the stomach and deliver metformin to the upper GI tract over an extended period nbsp; Can Metformin Be Cut? Diabetes Daily I have seen a variety of opposite answers for this on a google search. I have metformin tablets 500mg. I do not believe that they are extended release as the doctor did not write the prescription that way. I would like to split one in half to take half at lunch and half at dinner times. Can these be cut? Quote nbsp; Glucophage XR Uses, Side Effects amp; Warnings affect Glucophage XR? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Other drugs may interact with metformin, including prescription and nbsp; Metformin Extended Release Tablets FDA prescribing information not produce hypoglycemia in either patients with type 2 diabetes or normal subjects (except in special circumstances, see In patients with decreased renal function, the plasma and blood half-life of metformin is prolonged and the renal clearance is decreased (see Table 1; also see nbsp; Diabetes Update: Metformin vs Metformin ER The problem with breaking Metformin ER in half is this: The Extended Release feature of the drug is caused by it being encapsulated in some kind of matrix that digests slowly as it passes though your digestive tract. If you cut it, it will digest faster, so you no longer get the slower, longer action. If it is working nbsp; quot;Do No Continue reading >>

Can Glucophage Xr Be Cut In Half - 249228 - Foodinfo.tv

Can Glucophage Xr Be Cut In Half - 249228 - Foodinfo.tv

Glucophage XR Uses, Side Effects amp; Warnings Glucophage XR used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is sometimes used together with insulin or other medications, but this medicine is not for treating type 1 diabetes. Glucophage XR may also be used for purposes not listed in this medication guide.Can you cut in half Metformin ER? PCOS Message BoardYour siggy says you are on 1000 mg. Are you taking 1000 mg tablets or 500 mg tablets? If you are on 1000 mg tablets, you might ask the dr for 500 mg tablets so that you don 39;t have to break the pill. If you are on 500 mg tablets, they do not need to be cut in half.Can Metformin Be Cut? Diabetes DailyCan Metformin Be Cut I would like to split one in half to take half at lunch and half at dinner times. Can these be cut Metformin vs. Metformin XR.can I cut Metformin 500mg ER in half to take? Yahoo AnswersIt 39;s in their design. Unfortunately, Metformin ER tablets are NOT in that group. You can 39;t chew, crush, cut or break in half. You have to take this tablet whole. If you are not on any other diabetes medications it is very, very, very unlikely that Metformin alone can cause hypoglycemia. Metformin can cause gastritis( unset stomach).Can glucophage be cut in half Metformin (Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet) is a prescription drug used for treating type II diabetes in adults and children.Cutting a 500 mg Metformin pill in 1/2 Type 2 Diabetes Cutting a 500 mg Metformin pill in 1/2. as long as its not the XR metformin, I can 39;t imagine it causing a problem. We cut the 500 in half.Kaufen Glucophage Xr Online Besten Preis ApothekeGlucophage Xr kaufen paypal bezahlen. Xr 1000 mg can a metformin pill be cut in half metformin Continue reading >>

Can I Cut The Metformin 1000 Mg In Half To Take 500 Mg Instead Of Having To Buy A New Perscription?

Can I Cut The Metformin 1000 Mg In Half To Take 500 Mg Instead Of Having To Buy A New Perscription?

Home Q & A Questions Can I cut the metformin 1000... Can I cut the metformin 1000 mg in half to take 500 mg instead of having to buy a new perscription? Definitely not, if you need the 1000mg to control your blood sugar. If the dr didn't order 500 mg, then you can't cut it. If you google metformin discounts, you will find coupons that bring the cost down to around 12. Still looking for answers? Try searching for what you seek or ask your own question . Can I cut metformin 500 mg pill in half? I'm feeling better, do I need the entire pill? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to receive email notifications whenever new articles are published. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated Feb 28th, 2018), Cerner Multum (updated Mar 15th, 2018), Wolters Kluwer (updated Mar 1st, 2018) and others. To view content sources and attributions, please refer to our editorial policy . Continue reading >>

Proper Use

Proper Use

Drug information provided by: Micromedex This medicine usually comes with a patient information insert. Read the information carefully and make sure you understand it before taking this medicine. If you have any questions, ask your doctor. Carefully follow the special meal plan your doctor gave you. This is a very important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment. Swallow the extended-release tablet whole with a full glass of water. Do not crush, break, or chew it. While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about. Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way. You may notice improvement in your blood glucose control in 1 to 2 weeks, but the full effect of blood glucose control may take up to 2 to 3 months. Ask your doctor if you have any questions about this. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the Continue reading >>

More in diabetic diet