Diabetes Can Be Cured, But Not By Targeting Blood Sugar: Scientists
Increased blood sugar is only a symptom, not the root cause. Treating symptoms is not sufficient to reverse the condition New Delhi, August 7: In a provocative piece of research, scientists in a Pune-based institute used computer simulation to show that the current treatment modalities are not the best for type 2 diabetes and a change in approach could make the nasty disease one of the curable. The scientists led by evolutionary biologist Milind Watve at the Indian Institute of Science (IISER) Pune, created a computer model by putting together for the first time all known metabolic, hormonal, neuronal, immunological and behavioural signals involved in the onset of diabetes and in its manifestation in the human body. Network model To construct the network model, Watve’s team scoured nearly 500 published papers. This helped them identify as many 330 different interactions — involving over 70 molecules or signals — associated with diabetes. “Glucose and insulin are just two of them,” Watve told BusinessLine. “The network is like a giant cobweb in which perturbing one thread perturbs the entire network,” said Shubhankar Kulkarni, Watve’s PhD student and first author of the paper, which appeared in the journal PLOS One last week. Significantly, even though the effects are complex, they are far from being chaotic, he said. The IISER scientists, to their surprise, found that the network is highly structured and with any perturbation it ends up in either of the two possible configurations – one is insulin-sensitive and the other insulin-resistant. Using the model, the researchers could not only mimic many known patterns and processes associated with diabetes, but could also make a number of surprising predictions, the remarkable one being that diabetes can be Continue reading >>
The Cure For Type 2 Diabetes Is Known, But Few Are Aware
The cure for type 2 diabetes is known, but few are aware I recently posted to Facebook about a cure for diabetes and suggested someone try it. Just six days later, I received the following message from a friend: I just wanted to drop you a line and thank you for that post… My lab results at the beginning of the month were 230. After just this last week it’s down to 155. I think I’ll be in normal range within a month. Really miraculous… It’s really been a game changer for me already and I wanted you to know how much I appreciated the info and how much of a difference I think it will make in my life. Four months later, the friend posted this to Facebook: I started on this regiment when Nathan posted about it [four months ago]. My blood glucose level at that time, while taking two daily glucose meds, was 235. Two weeks ago, my [fasting] glucose level, WITHOUT the meds, was 68. If you google “diabetes cure” you are directed to websites like WebMD and the Mayo Clinic where you find information on diet, exercise, medication, and insulin therapy, but nothing about the cure. This lack of information may have to do with the fact that Americans spend $322 billion a year to treat diabetes, $60 billion a year on weight-loss programs, and $124 billion a year on snack foods. This is about 3% of the US economy! Because so many peoples’ livelihoods are supported by diabetes and its main cause, obesity, the viral effect of people getting cured and telling others is greatly diminished. Because of this understandable stifling of the message, if you are like my Facebook friend and have already experienced the type 2 diabetes cure for yourself — there are thousands of you out there — it is important for you to share your success stories as far and wide as possible. You c Continue reading >>
Is There A Conspiracy Preventing A Diabetes Cure?
For as long as there has been research to cure diabetes, there have been people who believe that a cure will never happen because treating this disease is simply far too profitable. Those who believe in this so-called "conspiracy theory" are convinced that pharma companies have a vested interest in keeping diabetes around as long as possible because peddling their treatments is far bigger business than a cure could ever be. We all know that diabetes is a multi-billion dollar industry, including sales of insulin, oral agents and injectibles like Victoza, and medical devices such as insulin pumps, glucose monitors and their pricey test strips, and new continuous glucose monitors. Type 2 diabetes is increasing exponentially, but even type 1 diabetes is growing at a dramatic rate, which means more and more consumers. The latest flare-up over a possible "conspiracy" occurred in August, when a news article about controversial researcher Dr. Denise Faustman circulated around the diabetes community. In the article, Faustman says that when she approached pharmaceutical companies for funding, she was told "there wasn't enough money to be made in a cure that used an inexpensive, generically available vaccine." But is that even true? Certainly, there are legitimate financial considerations these companies' research & development decisions. But does that mean they never work on cure research? Would pharma really sweep a possible cure under the rug to protect their own interests -- especially if it turned out to be a cheap vaccine? Who's to say? We decided it would be fascinating to tap some prominent experts in the diabetes community to get their perspective on the "D-conspiracy theory." Exploring Motives Kelly Close, a type 1 PWD and president of diabetes consulting firm Close Conc Continue reading >>
New Goal For Type 1 Diabetes Cure
Diabetes affects over 422 million people worldwide according to the World Health Organization, but no two patients are alike. So in 2017 and beyond, treatments will increasingly make use of precision medicine to personalize treatment options. At City of Hope, researchers are using a transformative gift to speed these treatments to patients. On January 16, the Wanek family bestowed City of Hope’s Diabetes and Metabolism Research Institute with a significant contribution to support the institution’s goal of curing type 1 diabetes (T1D) in six years and create The Wanek Family Project for Type 1 Diabetes. The gift follows on the heels of an alliance between City of Hope and the Translational Genomics Research Institute (TGen), an organization that applies genomic analysis and bioinformatics in the development of personalized approach to therapies for diseases like cancer and diabetes. “One of the lessons we’ve had recently is that every patient is different,” said Bart Roep, M.D., Ph.D., director of the Wanek Family Project. “So you really have to do a fine diagnosis, like we do in cancer, to offer the best type of therapy to the individual patient — something we call personalized medicine, or precision medicine.” But for that, he says, researchers first need to understand what makes one T1D patient different from another. They also need to understand the mechanisms behind how the immune system mistakenly destroys beta cells — the cells that make insulin — to cause T1D. “That is what the Wanek Family Program entails, and we’re taking it from different angles,” said Roep, who is also the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and Professor and founding Chair, Department of Diabetes Immunology at City of Hope. We have people here t Continue reading >>
Why There Will Never Be A Cure
This is a conversation that I had today at lunched. Now, some of you may agree and some of you will disagree, strongly. The discussion was brought up about the $100 million Obama is going to send to the care of Haiti. The question was posed to me, “Doesn’t that piss you off that they send $100 million to another country, and that money could be spent on diabetes research?” Now, I didn’t know how to answer this question at first. Of course I don’t want to see anybody have to suffer, but I also see the side that my tax money could go to something like research instead. So, my answer was, “well, there will never be a cure.” And then the conversation went on with my explaining why, which I will here as well. And it can be summed it very easily. You think we are in a recession now? Find a cure to diabetes and see what kind of recession we hit. How would scientists that spent their whole life searching for a cure and doing studies about diabetes get a paycheck if there was a cure? How would they pay their bills. How would the stores they shop at be affected. How would the people that work for diabetes companies and products make a living? It would hit our economy harder than just about anything. Do I hope for a cure, of course! Do I still donate funds and do volunteer work, of course. But realistically, no, I don’t think it is likely. There will be advancements in the management of it and there will be tools that may make it easier to live with diabetes and maybe even ways to rid yourself of all complications, but never a cure. Companies can still make money off of advancements, but not off of a cure. But like I said before, this thought will not stop me from doing what I can to help find one. Do any of you share this same feeling? Continue reading >>
A Team Cured Diabetes In Mice Without Side Effects
A Cure for Diabetes A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots. The discovery, made at The University of Texas Health Science Center, now called UT Health San Antonio, increases the types of pancreatic cells that secrete insulin. UT Health San Antonio researchers have a goal to reach human clinical trials in three years, but to do so they must first test the strategy in large-animal studies, which will cost an estimated $5 million. Those studies will precede application to the U.S. Food and Drug Administration for Investigational New Drug (IND) approval, Bruno Doiron, Ph.D., a co-inventor, said. The scientists received a U.S. patent in January, and UT Health San Antonio is spinning out a company to begin commercialization. The strategy has cured diabetes in mice. “It worked perfectly,” Dr. Doiron, assistant professor of medicine at UT Health, said. “We cured mice for one year without any side effects. That’s never been seen. But it’s a mouse model, so caution is needed. We want to bring this to large animals that are closer to humans in physiology of the endocrine system.” Ralph DeFronzo, M.D., professor of medicine and chief of the Division of Diabetes at UT Health, is co-inventor on the patent. He described the therapy: “The pancreas has many other cell types besides beta cells, and our approach is to alter these cells so that they start to secrete insulin, but only in response to glucose [sugar],” he said. “This is basically just like beta cells.” Insulin, which lowers blood sugar, is only made by beta cells. In Type 1 diabetes, beta cells are destroyed by the immune system and the person has no insulin. In Type 2 diabetes, beta cells fail Continue reading >>
Can Moringa Leaf Cure Your Diabetes?
In Asia and Africa, the Moringa leaf is hailed as a cure-all. Although it is most commonly used to treat malnutrition in developing countries, some doctors allege that the Moringa leaf can help over 300 diseases, including diabetes. Despite these claims, people in the Western Hemisphere know little about this natural supplement’s possible benefits. The Moringa leaf is a nutrient powerhouse because it possesses large quantities of vitamins A, C, calcium, iron, and protein. Due to its abundance of vitamin A, Moringa may prevent diabetic retinopathy. Research has shown that vitamin A supports eye health by preventing inflammation and strengthening the corneas. This is significant because 28.5% of people over 40 with diabetes have developed diabetic retinopathy between 2005 and 2008. Moringa is also rich in vitamin C. Combined with insulin, vitamin C can halt blood vessel damage in people with Type 1 diabetes, decreasing their risk for chest pain, heart attack, and stroke. Some users credit the Moringa herb for reducing tumour size and blood pressure. The supplement can also boost your immune system. For people with diabetes, these benefits could be significant due to their increased risk for heart disease and cancer. For people with insulin resistance, dangerously high levels of blood glucose could cause excessive amounts of inflammation, resulting in limited blood flow. This lack of blood flow can lead to a heart attack or stroke. Weight management is another potential pro in taking Moringa leaf because of the amount of protein it possesses — foods high in protein can reduce cravings in between meals. Moringa leaves can be eaten raw, cooked, or made into powder. While raw Moringa leaves taste like radishes, cooked Moringa is similar to spinach. Using Moringa powder in Continue reading >>
Experts Are Confident A Cure For Diabetes Will Be Discovered In The Next 25 Years
Researcher and diabetes consultant Dr Nick Oliver said he hopes for a cure 'within a generation' 39-year-old said Britain is leading the race to develop a cure A leading expert has claimed diabetes could be cured in the next 25 years. Researcher Dr Nick Oliver, diabetes consultant at Imperial College Healthcare NHS Trust, said he expects to see the condition wiped out before he retires. He told The Daily Express Britain is leading the race to combat the disease, which is caused by the pancreas failing to any insulin (Type 1) or insufficient levels of the hormone (Type 2). Insulin is needed to break down sugar in the blood to allow the body to use the glucose as fuel. The disease is expected to affect 6.25million people by 2035, and already costs the NHS £1million an hour in treatments and drugs. Dr Oliver said: 'There are lots of avenues that will lead to potential cures for Type 1 and Type 2 diabetes and if I could see it in my career that would be incredibly exciting.' 'Diabetes can’t be cured at the moment. The race is on to get effective treatments for people. Their quality of life is important.' Dr Oliver, 39, is currently leading a team carrying out human trials on the world's first artificial pancreas. If successful the step forward would offer the 400,000 sufferers of Type 1 diabetes - when a person's body cannot produce enough insulin - a new and effective treatment. The Bio-Inspired Artificial Pancreas – BiAP – is attached to the abdomen via a thin tube. The device reads a patients' sugar levels and transmits information to an insulin pump. The pump then releases hormones as and when it is needed. The invention would eliminate the need for daily blood tests and injections, required by diabetics. Jess Bristow, 46, of Surrey, one of 20 in the trial, said: Continue reading >>
Introduction To Type I Diabetes
Three Articles On Type I Diabetes: Article #1: Introduction to Type I Diabetes (This Article) Article #2: Possible Causes of Type I Diabetes Article #3: The Treatment of Type I Diabetes Introduction to Type I Diabetes Did you know that there are two products that have cured advanced Type I diabetes cases? Both of them will be discussed in this article. But more importantly, one of these products can reverse cumulative severe side-effects of Type I or Type 2 diabetes. Type I diabetes is actually a set of symptoms, meaning it can be caused by several different things. The symptoms are that the blood lacks insulin. There are actually several things that can cause an abnormally low level of insulin in the blood. Type I diabetes is a very severe disease. The average lifespan of Type I diabetic is 5-8 years shorter than an average person. But death is not the worst thing about Type I diabetes. Here is a list of some of the health problems it can lead to: Amputation of limbs Blindness (retinopathy) – diabetes is the leading cause of new cases of blindness in America — 12,000 to 24,000 case annually Kidney failure (nephropathy) – frequently leading to dialysis or a kidney/pancreas transplant Liver disease Arteriosclerosis (hardening of the arteries) Heart disease Stroke (e.g. paralysis) High blood pressure Nerve damage (neuropathy) Dementia Urinary tract infection (mostly in women) Depression – Note: Aspartame (e.g. Equal, NutraSweet, etc.) and sugar are the leading causes of depression in non-diabetics. However, because the average diabetic consumes more aspartame than the average person, it is highly possible that aspartame is by far the REAL cause of depression in diabetics!! A diabetic should absolutely avoid aspartame and all other artificial sweeteners! Bone quali Continue reading >>
Scientists Cure Type 1 Diabetes For A Year Without Side Effects
A potential cure for Type 1 diabetes looms on the horizon – and the novel approach would also allow Type 2 diabetics to stop insulin shots. The treatment totally cured diabetes in mice for an entire year without any side effects. The discovery, made at UT Health San Antonio, works by increasing the types of pancreatic cells that secrete insulin. “It worked perfectly,” said Dr. Bruno Doiron, assistant professor of medicine at UT Health. “We cured mice for one year without any side effects. That’s never been seen.” CHECK OUT: First Ever Quadriplegic Treated With Stem Cells Regains Motor Control in His Upper Body Insulin, which lowers blood sugar, is only made by beta cells. In Type 1 diabetes, beta cells are destroyed by the immune system and the person has no insulin. In Type 2 diabetes, beta cells fail and insulin decreases. At the same time in Type 2, the body doesn’t use insulin efficiently. The therapy is accomplished by a technique called gene transfer. A virus is used as a vector, or carrier, to introduce selected genes into the pancreas. These genes become incorporated and cause digestive enzymes and other cell types to make insulin. Unlike beta cells, which the body rejects in Type 1 diabetes, the other cell populations of the pancreas co-exist with the body’s immune defenses. Gene transfer using a viral vector has been approved nearly 50 times by the U.S. Food and Drug Administration to treat various diseases. MORE: After Marrying On Her ‘Deathbed,’ This Bride Made a Miraculous Recovery After Quitting 1 Food “The pancreas has many other cell types besides beta cells, and our approach is to alter these cells so that they start to secrete insulin, but only in response to glucose [sugar],” said co-inventor Ralph DeFronzo. “This is basicall Continue reading >>
Treatments That Cure Type 2 Diabetes – T2d5
It surprises some people that there are, indeed treatments that cure Type 2 Diabetes (T2D). Bariatric surgery is one such treatment. Fasting protocols have been known for close to 100 years to cure diabetes as well. Very Low Carbohydrate (sometimes also called ketogenic diets) can also sometimes cure T2D. Consider a recent case that I saw. A 27 year old physiology student was diagnosed with T2D when she showed up for her routine medical check up. Her bloodwork had shown a HgbA1C of 10.4%. That is pretty bad. Normal is less than 6.0% and T2D is diagnosed at 6.5%. So she was well, well within the range of diabetes. Her physician immediately started her on 3 medications. However, being so young, she didn’t want to take them. So she searched around on the Internet and decided to start a ketogenic diet. Three months later, her A1C was 5.5% even off of all her medications! Her T2D was, in fact, completely cured. Stories like this abound on the Internet. Here’s a story from Brian from www.dietdoctor.com. Or Mike. He received a diagnosis of diabetes, but instead of going onto medications, he changed his diet to a LCHF (Low Carb High Fat) diet and his sugars normalized. You may also have heard of a recent case of a Texan 3 year old with T2D. Yes. A 3 year old. Her diet consisted mostly of candy, sugary drinks and fast food. The toddler was initially placed on metformin, a drug commonly used in adults for T2D. However, with proper diet, she was able to stop her medication and her sugars returned to normal. After 2 years, it might be argued that proper diet ‘cured’ this patients diabetes. This doesn’t seem too difficult to figure out, really. Refined carbohydrates are well known to be one of the worst offenders for raising blood sugars. They also don’t have any redeemi Continue reading >>
Can Type 2 Diabetes Be Cured Or Reversed With Weight Loss?
Type 2 diabetes is not curable, and cannot be reversed with weight loss. Weight loss and regular exercise will help overweight patients with type 2 diabetes return to normal blood glucose (sugar), but diabetes will never go away. With a healthy lifestyle that includes diet, exercise and possibly medication including insulin injections that will help blood glucose stay in the normal range. Diabetes can be well-managed. Source: Continue reading >>
Type 2 Diabetes Is A Fully Curable Disease
Type 2 diabetes is a fully curable disease. And still conventional medicine treat it as the opposite – as a chronic and progressive disease. We try to mask the symptoms and slow down the complications, instead of curing it! It’s quite easy to prove that type 2 diabetes is a curable disease. Have a look at this chart of the number of required drugs for treating the disease, over 12 months on three different treatments in a 2012 study: The top graph is conventional treatment. Everyone starts out on three different medications and they keep having to take the drugs. This is what we normally do. It simply does not work as a cure and may even make the diabetes worse. The bottom two graphs are common variants of obesity surgery, where a large (healthy) part of the stomach is removed. Many patients suddenly don’t need drugs anymore, their diabetes completely goes away! The point is not to recommend surgery that removes healthy organs – I don’t recommend that. The point it that type 2 diabetes is a fully curable disease. Luckily it’s not even necessary to remove healthy organs to do so, it’s also possible by just changing your lifestyle. Here’s a longer post on the subject by the great Dr. Jason Fung: IDM: Surgery Reverses Diabetes – T2D3 I just spent a few days with Dr. Fung and we have some really interesting plans. If you’re at all interested in this topic I think you’ll love what we have coming up soon. More Continue reading >>
Stay Well & Sparkle: Can Diabetes Be Cured?
“Mama, how come your mout’ so long?” Little Pig asked innocently. “Just wait till you grow up,” Mama Pig answered, “and you’ll find out!” Diabetes is like that. It may be a nuisance to keep up with and it doesn’t really hurt in the present. Not until the disease ‘grows up’ in a patient over the years do we find out the harvest of ill effects. Every now and again, we are shocked to hear of some young person having to go on dialysis, or of some dear middle-aged person getting a stroke or amputated. Instead of ‘acts of God’ coming out of nowhere, these are largely the direct consequences the things we do and don’t do. Readers of the diabetes article a couple weeks aback know how deceitful and deadly it is. So much so, Dr. Max Pemberton is a British AIDS specialist compared exploding ravages of diabetes to advances made in his own field. He went as far as to declare: “I’d rather have HIV than Diabetes.” Our gut reaction is “What nonsense mister talking there, nuh!” But if you read the article, you have no choice but see where he is coming from. You see; if diabetes were a contagious disease, health officials would be way more freaked out about it than Ebola. Yet long after that lethal virus has disappeared from the headlines, the specter of diabetes will continue to stalk the world at exponential speed. And Dominica is right up there, in the thick of things. That is why it was so gratifying to see all the people who came to check their HbA1C – the best indicator of whether we have diabetes or about to. Did you? Some people have Type 1 diabetes where the pancreas, which produces insulin, is destroyed by some weird autoimmune condition. That’s a done deal over which we have little or no control other than taking insulin shots or pump Continue reading >>
Changes In One’s Diet Is Not A Cure For Diabetes
I cannot see the E on the eye chart with my natural eyes. I know that the first symbol is an E because I’ve been taking eye exams since I was 10 years old. Since the 5th grade, I’ve been wearing eye glasses, in high school I switched to contacts, and from college until I now I enjoy switching between the two. I have needed corrective lenses for more than two decades in order to see “normally” and I have never had anyone (not even once) say to me “eye glasses have cured your poor vision.” It easy for people to accept that my eyes are bad and they will be that way for the rest of my life. It’s widely accepted that carrots will not restore my vision. Matter of fact, eye glasses have become in vogue (thankfully) and people who don’t need eye glasses want to wear them. Everyone knows that when it comes to having vision as poor as mine that Lasik is the only cure. Lasik eye surgery will give me the ability to see IMMEDIATELY and I will be able to donate my eye glasses and contacts to someone else because I will NEVER need them again. I may need reading glasses at some point, but my extreme case of myopia (nearsightedness) will be gone…FOREVER! This, we get. This, I have no problem explaining. This, gets me urgent responses when I say, “Help, I can’t find my eye glasses!” However, when it comes to diabetes, things are quite different. It’s hard for people to accept that my pancreas is like my eyes–another vital part of me that will NEVER be “normal” again. When I tell people that I manage diabetes with diet and exercise, some are determined to hear me say that I am “cured.” Well, I am not. Diet and exercise are like wearing contacts or eye glasses….they help me “MANAGE” the problem, it hasn’t cured it. Recently I got into a discussio Continue reading >>