Diabetes Could Be Cured As Scientists Find Cause Of Disease
Diabetes could be cured after scientists discovered that toxic clumps of a hormone stop cells producing insulin. Scientists at Manchester University have found that both Type 1 and Type 2 diabetes are driven by the same underlying mechanism. The findings suggest that both forms occur when the hormone amylin begins to clump together, surrounding cells, and preventing them from producing insulin. Insulin is essential for moving sugar from the blood stream into muscles and fatty tissue to provide energy. But too little insulin allows dangerous levels of glucose to build up in the blood, causing damage to the heart kidneys, eyes and nerves. However the new finding could pave the way for drugs which stop the amylin build-up in the first place or dissolve clumps which are already present. Related Articles Full fat milk and cheese reduce the risk of diabetes: study 16 Sep 2014 What are stem cells? 09 Oct 2014 I never thought I was the type who would develop diabetes 11 Jun 2014 One in three adults have borderline diabetes, study finds 10 Jun 2014 Women with diabetes at greater heart risk than men: study 23 May 2014 The NHS is collapsing under the weight of demand 11 Jun 2014 More than three million people in Britain have been diagnosed with diabetes, with that figure expected to five million by 2025. The vast majority of sufferers (85 per cent) have Type 2 diabetes, which is linked to obesity, poor diet and sedentary lifestyles. More than 70,000 deaths a year occur among those suffering from the condition - one in seven of all deaths. The pancreas produces both insulin and amylin which usually work together to regulate the body’s response to food. However, some of the amylin that is produced can get deposited around cells in the pancreas as toxic clumps, which then, in turn, Continue reading >>
Diabetes Is Incurable But Can Be Managed
Although some of the world’s best scientists have been working on it for decades, a permanent and complication-free cure for type 1 and type 2 diabetes mellitus has yet to be developed. Pancreas transplant can be performed on type 1 diabetes patients who have developed serious complications. The healthy pancreas is taken from a brain-dead donor on life support. Pancreas transplant is usually done in conjunction with a kidney transplant. Like any major surgery, it carries a high risk of surgical complications. Transplant patients need to take medicines in order to prevent organ rejection; these medicines suppress the immune system and make patients vulnerable to infections. Another potential cure is beta cell transplantation. The beta cells of the pancreas are progressively damaged in patients with diabetes. Once transplanted, the healthy beta cells from the donor begin to make and release insulin that keeps blood glucose within normal levels. Like all organ transplant procedures, beta cell transplantation is associated with surgical complications, organ rejection and immune suppression caused by antirejection medicines. It has yet to be performed in the Philippines. Scientists are experimenting on stem cell therapy for type 1 diabetes in mice. Stem cells are cells that can develop into other types of cells, including beta cells. Scientists of a California biotech company prepped human embryonic stem cells to develop into beta cells. After prepping the cells, they grafted them onto the abdominal fat of mice. Two months later, the implanted cells began producing insulin. Although promising, stem cell therapy for diabetes is still a distant reality. Bariatric surgery or weight-loss surgery can be considered in obese patients with type 2 diabetes. It involves making chang Continue reading >>
Can You Really Reverse Diabetes?
Most health care professionals will tell you that type 2 diabetes is a chronic, progressive and incurable disease (it’s the seventh leading cause of death in the United States). But some small recent studies have raised the tantalizing possibility that diabetes could go into remission — at least partially, at least temporarily, at least in a subset of patients. Thanks to the aging of the population and the increasing prevalence of obesity, both of which are risk factors for type 2 diabetes, the disease has been a growing public health problem in the United States. From 1980 through 2014, the number of Americans diagnosed with diabetes nearly quadrupled, from 5.5 million to 21.9 million, the vast majority of whom have type 2, according to the Centers for Disease Control and Prevention. In people with type 2 diabetes, their bodies don’t use insulin properly, which is called insulin resistance. Early on, the pancreas makes extra insulin to compensate, but over time it can’t produce enough to maintain normal blood sugar levels. Bariatric Surgery May Help As a review article in the June issue of Current Diabetes Reports notes, however, weight-loss surgery provides a short-term cure for diabetes in more than seven out of 10 cases. The non-surgical way to [reverse diabetes] is by going on a very low-calorie diet, which can remove fat that’s clogging the pancreas and blocking secretion of insulin. — Dr. Roy Taylor, Newcastle University, U.K. “It is extraordinarily effective in treating diabetes,” says Dr. Pankaj Pasricha, director of the Center for Neurogastroenterology at the Johns Hopkins University School of Medicine in Baltimore. “This is before they lose even a pound of weight.” In fact, many patients no longer need insulin by the time they’re dischar Continue reading >>
What Is Diabetes?
Diabetes is an incurable condition in which the body cannot control blood sugar levels, because of problems with the hormone insulin. There are two main variations of the illness, Type I and Type II. How does the body control blood sugar levels? Your body uses blood sugar (glucose) for energy. Glucose is a basic ingredient of sweet foods such as sweets and cakes. It can also be produced by carbohydrates such as potatoes, pasta or bread when they are digested and broken down. Under normal circumstances, the hormone insulin, which is made by your pancreas, carefully regulates how much glucose is in the blood. Insulin stimulates cells all over your body to absorb enough glucose from the blood to provide the energy, or fuel, that they need. After a meal, the amount of glucose in your blood rises, which triggers the release of insulin. When blood glucose levels fall, during exercise for example, insulin levels fall too. Types of diabetes There are two main types of diabetes. In Type 1 diabetes the cells of the pancreas stop making insulin. In Type 2 diabetes, either the pancreas cells do not make enough insulin, or the body's cells do not react properly to it. This is known as insulin resistance. Type 1 diabetes is an autoimmune condition, and the immune system attacks the cells of the pancreas. It tends to affect people before the age of 40, and often follows a trigger such as a viral infection. The exact mechanisms that lead to Type 2 diabetes are not fully understood, but an underlying genetic susceptibility is usually present. This could be a family history of the illness, for example. The condition is then triggered by lifestyle factors - such as obesity - and it usually appears in people over the age of 40. There are three other, less common, forms of diabetes: Gestati Continue reading >>
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Will Diabetes Go Away?
There is no cure for diabetes. Neither type 1 (juvenile onset or insulin-requiring) diabetes or type 2 (adult-onset) diabetes ever goes away. In type 1 diabetes, patients sometimes experience what physicians have come to call a "honeymoon period" shortly after the disease is diagnosed. During the "honeymoon period" diabetes may appear to go away for a period of a few months to a year. The patient's insulin needs are minimal and some patients may actually find they can maintain normal or near normal blood glucose taking little or no insulin. It would be a mistake to assume that the diabetes has gone away, however. Basically, type 1 diabetes occurs when about 90 percent of the body's insulin-producing cells have been destroyed. At the time that type 1 diabetes is diagnosed, most patients still are producing some insulin. If obvious symptoms of type 1 diabetes emerge when the patient has an illness, virus or cold, for example, once the illness subsides the body's insulin needs may decrease. At this point, the number of insulin-producing cells remaining may be enough — for the moment — to meet the person's insulin needs again. But the process that has destroyed 90 percent of the insulin-producing cells will ultimately destroy the remaining insulin-producing cells. And as that destruction continues, the amount of injected insulin the patient needs will increase — and ultimately the patient will be totally dependent on insulin injections. Scientists now think that it is important for people with newly diagnosed diabetes to continue taking some insulin by injection even during the honeymoon period. Why? Because they have some scientific evidence to suggest that doing so will help preserve the few remaining insulin-producing cells for a while longer. Patients diagnosed wi Continue reading >>
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Is Diabetes The Easiest Incurable Disease To Cure?
I don’t know if you’ve noticed, but an incurable disease is being cured. I went over to my local library last fall, to do some research on diabetes. It was an interesting experience. I picked about 10 books off the shelf, and took them to a study table. You can see a list in the references at the bottom. One of the books, one in ten, claimed to cure diabetes. The others provided ‘treatments’ and guidelines on ‘how to live with your diabetes’, assuming, even stating clearly in most cases, that “diabetes cannot be cured”. The truth is a bit longer sentence: “”Diabetes cannot be cured by medicines”. There are two ‘types’ of diabetes. Type 1 Diabetes (in theory) exists when your body loses ALL of the islet cells in the pancreas, thus, according to the Theory of Cures, it is a disability, not a disease. Disabilities cannot be cured. But if the theory is wrong, if our understanding of type 1 diabetes is wrong, it might be curable. Or maybe it’s curable some of the time? Type 2 diabetes covers a wide range of conditions, with causes and contributing factors. It is a disease with an ongoing cause so, in theory, it can be cured. But what do the medical authorities say? According to MERCK the bible of medical diagnosis and therapy, diabetes is incurable. The goals of treating diabetes are: ‘Treatment involves control of hyperglycemia to relieve symptoms and prevent complications while minimizing hypoglycemic episodes.‘ The American Diabetes Association is not actively looking for a cure, even though their website suggests “Give a tax-deductible donation today to get us closer to a cure.” Their webpage has seven section headings suggesting we learn to ‘live with diabetes’. Their stated mission is “To prevent and cure diabetes and to improv Continue reading >>
Is Type 2 Diabetes Reversible? Your Guide In 2017
“Is type 2 diabetes reversible, doctor?” It’s a common question I get asked by many people that I meet. When I was back in medical school more than 10 years ago, we were all taught that type 2 diabetes is a chronic disease. Which means that it will be there with you 24 hours a day, 7 days a week and it doesn’t go away. Essentially, it is incurable. And once you’ve been diagnosed with diabetes, the best you can do is to try to manage it as best as you can. Today, the answer is no longer clear cut. Thankfully, in a positive way. Let’s take a deeper look at what the science tells us. What is Type 2 diabetes? Type 2 diabetes is a relatively common metabolic disorder that results in high blood glucose levels in your body. Did you know that over 415 million people today are living with diabetes globally? If you have diabetes, you’re far from being alone. The condition arises from a combination of high insulin resistance in the tissues of our body and decreased insulin secretion by the pancreas, an internal organ. Insulin is an important hormone that allows our cells to properly absorb and use glucose. Insulin serves to regulate our blood glucose levels and keep it at a constant, normal level. Some factors that can put you at higher risk of Type 2 diabetes include a strong family history of the disease (genetics), obesity (lifestyle) and age. If you’re worried that you may have diabetes, you can find out more about the symptoms of diabetes here. Is Type 2 diabetes reversible? Even though diabetes is commonly thought of as a chronic disease, our understanding of it has improved greatly over the past few years. Here is where I want to point to 2 particular areas that can shed some light on this matter: 1. Sustainable weight loss may answer the question “is type Continue reading >>
Is Diabetes Curable?
You have raised a very valid point.....but still hope is alive...so many things are going on as far as research on this disease is concerned....and a lot needs to be done before any treatment is finally out for general use...as we all know that genomes being sequenced, getting SNPs and even subsequently much more in depth analysis...may not be able to answer all the queries.....life of any organim is hihgly complex.....Even in model organism like E.coli....which was sequenced a long ago...a large number of genes are still there in the genome with 'no assigned function'.....and situation becomes more complex with entry of newer 'candidates'....and a good example is small RNA based gene regulation....life is definitely complex..... Continue reading >>
Diabetes – The Incurable Disease
Health is the real jewel and the most precious possession of man. An increasing concern in the world is the declining health of the people due to a poor diet. Diabetes is among such lifelong diseases as have no cure. Diabetes is a condition where the amount of glucose in human blood is very high because the body cannot use it properly. This is because your pancreas does not produce insulin, or not enough insulin, to help glucose enter your body’s cells. It is the cause of 88,000 deaths per day of which 35,615 are men and 52,397 are women. Pakistan is a poor country having very little quota for health budget. The alarming figure is that Pakistan is the 7th largest country in terms of Diabetes population and it will be 4th largest by the year 2030. According to World Health Organization (WHO), in the year 2011, 12.9 million Pakistani people were suffering from diabetes of which 9.4 million were diagnosed and the remaining 3.5 million people were undiagnosed. Different non-profit organizations are working to serve humanity by spreading the awareness about diabetics. The very first one to educate the Pakistanis about the disease is the Diabetic Association of Pakistan (DAP). The Diabetic Association of Pakistan (DAP) was established in 1966 with 41 employees and 21 volunteers and the mission is to provide specialized medical care and education to the people suffering. The outpatient clinic of DAP was affiliated with International Diabetes Federation (IDF) in 1967. It is one of the oldest members of the IDF and 13th in order of affiliation. Illahi Bukhsh Soomro is patron of DAP and he was the 16th Speaker of National Assembly of Pakistan. He is from a political family of Sindh. Starting from an eye clinic for diabetic patients in 1982, the DAP developed its network for hum Continue reading >>
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Diabetes Myths
Author's Perspective: When I was diabetic, I was confused by a lot of the misinformation about diabetes. People who I thought were experts turned out not to be experts. Fortunately, because of my science background, it made it easier for me to separate fact from fiction. The one important thing to remember about most of these myths is that they are designed to keep you afraid, uncertain, diabetic and/or dependent on drugs, uninformed doctors and other so-called "experts". I learned very quickly that the only person who had a vested interest in my long-term non-drug health was me! -- so, I had to become my own expert. There are many myths about diabetes. Some of the myths were started through ignorance, others by doctors, dietitians and diabetes educators, others by flawed studies, and still more exist because of slick manipulative marketing, lack of knowledge, resistance to change by diabetics, and taking the path of least resistance. Although it is very important to learn everything you can about diabetes, it may be just as important to unlearn a lot of things you believe to be true about diabetes, drugs, and nutrition. Here are some of the many myths and misunderstandings about diabetes, drugs, nutrition and other related topics. Myth: Diabetes is just a little sugar problem – it’s not that serious. Truth: Diabetes is a disease that affects trillions of cells in the body and, gradually, leads to complications such as heart attack, stroke, amputation, kidney failure, and blindness. So, diabetes is a very serious problem . . . a very serious problem. Myth: Only some people end up with a major health problem such as a leg amputation, kidney failure, blindness, heart attack, or stroke. Truth: No! All diabetics eventually end up with one or more diabetic complications Continue reading >>
Berry's Miracle Cure Probably Misdiagnosis, Say Docs
Despite her claims to the contrary, Halle Berry did not cure herself of Type 1 diabetes, doctors told ABC NEWS.com, for one simple reason -- Type 1 diabetes is incurable. "I've managed to wean myself off insulin, so now I'd like to put myself in the Type 2 category," the Web site contactmusic.com quotes the Academy Award winning actress as saying last week. Diabetics quickly took to the blogosphere to condemn Berry for claiming that a change in diet could cure Type 1 diabetes, an autoimmune disease in which the pancreas permanently fails to produce insulin, the vital hormone that regulates sugar levels in the blood. Type 1 diabetes, once known as juvenile-onset diabetes, usually strikes children who must remain on insulin therapy for their entire lives, routinely monitoring their blood-sugar levels and taking injections. Those doctors interviewed agreed that if Berry was truly a Type 1 diabetic, it would be suicide to simply stop taking insulin. They surmised that the 41-year-old actress was either mistaken, misinformed or misdiagnosed, and probably always had Type 2, which tends to affect people later in life and can in some cases be overcome with a change in diet. "When someone really has Type 1, it means their immune system has destroyed the insulin producing part of pancreas. In that case, there is no way to wean yourself off insulin [treatments]," said Dr. Francine Kaufman, a diabetes expert at Childrens Hospital Los Angeles. Some 20.8 million people -- 7 percent of the population -- have diabetes, according to the National Institutes of Health. African-Americans, however, are particularly at risk. According to institute statistics, 3.2 million black Americans, or 13.3 percent of all non-Hispanic blacks, have the disease. Berry's mother is white and her father is b Continue reading >>
Type 1 Diabetes Cure And Research Update – August 2017
Diabetes is an incurable disease. Sufferers usually depend on medication and treatment drugs to sustain their lives, and this usually causes extremely heavy financial burden on themselves and their family members. As a recap, type 1 Diabetes is a condition in which the immune system activates by itself to destroy cells in the pancreas which produces insulin. Globally, around 10-15% of diabetes are type 1. Given the incurable nature of the disease, patients usually try to survive for decades taking medications which are expensive and costly, just to stay alive. Regardless, sufferers could take comfort in the knowledge that there is indeed a focus on research to come up with true cures for the disease. Type 1 Diabetes Cure And Research Update – August 2017 University of Texas Health Science Centre Researchers in the US have managed to cure Type 1 Diabetes in mice. University of Texas Health Science Centre leveraged on a virus as a carrier to introduce insulin-producing genes into the pancreas of subjects (which in this case, are the mice). You can read more with the link above, but though this finding is encouraging, human trials have not started and more needs to be done to eradicate this disease. University of Tampere in Finland There could potentially be a vaccine for Type 1 Diabetes beginning human trials in 2018. This prototype vaccine is in place to potentially prevent Type 1 Diabetes from the onset in children. The research is currently being spearheaded by University of Tampere in Finland. It is postulated that a virus has been found to trigger the body’s defences into attacking itself (in this case, destroying cells in the pancreas) and the vaccine can provide immunity on that. If you are interested in the journal article on the virus (coxsackievirus B1) and Continue reading >>
Type 1 Diabetes Cure
Type 1 diabetes is mostly a treatable but largely incurable disease. The disease is caused by damaged beta cells in the islets of Langerhans of the pancreas that fail to secrete insulin. Insulin facilitates the uptake of glucose from the blood by muscle, fat, liver and other cells of the body where it is used as the energy source for various cellular functions. Since people with type 1 diabetes lack insulin, the main approach to treatment is the exogenous injection of insulin to restore a normal insulin level. To actually cure the condition would mean eliminating the basic pathology of type 1 diabetes and helping the beta cells secrete normal amounts of insulin. However, some such approaches that are currently in development include: Cell encapsulation Cell encapsulation aims to replace the pancreatic function through the creation of an artificial pancreas made from bioengineered tissue that contains the islet cells of the pancreas. This implant is programmed to secrete the correct amounts of insulin, amylin and glucagon hormones that are need for the normal regulation of blood glucose. In the case of transplant, immunosuppressant drugs are usually needed to prevent the body from mounting an immune reaction against the transplanted tissue and destroying it. With cell encapsulation, however, a protective coating is placed over the transplanted cells to protect them from immune attack, therefore prolonging their existence in the body as well as eliminating the need for immunosuppressant drugs. Cell encapsulation has not yet been successful in humans but is thought to hold promise for the future. Regeneration of the islet cells is another new approach where degenerating islet cells are allowed to proliferate to resume their functions. Transplantation of pancreas from a sui Continue reading >>
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Diabetes: It’s No More An Incurable Disease
What’s so special in Shubhpuja’s remedy? Shubhpuja is offering for the first time a completely holistic remedy and solution for the diabetes patient who have been suffering for the cause of nothing. They have been abandoned from the nectar of life i.e. Sugar and sweet. Through specially researched mantras by our expert team of pandits, acharyas, purohitas and mantra healing experts, we have come to the point to relieve the people from the pangs of suffering from diabetes and living a painful life Facts about Diabetes Diabetes mellitus is commonly known as “Sugar” in Indian vernacular language and is called Madhumeha in Ayurveda. Diabetes is one of the most common life threatening disease by which many people are suffering. It lies on the third number after Obesity and Hypertension in the world’s statistics of most common diseases of the world. Let’s see what WHO (World Health Organisation) has to say about it. Here’s an excerpt from their report for 2014. The number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014. The global prevalence of diabetes among adults over 18 years of age has risen from 4.7% in 1980 to 8.5% in 2014. Diabetes prevalence has been rising more rapidly in middle- and low-income countries. Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke and lower limb amputation. In 2012, an estimated 1.5 million deaths were directly caused by diabetes and another 2.2 million deaths were attributable to high blood glucose. Almost half of all deaths attributable to high blood glucose occur before the age of 70 years. WHO projects that diabetes will be the 7th leading cause of death in 2030. Definition of Diabetes As per the classical medicinal texts, Diabetes is a condition where the body fa Continue reading >>
Type 2 Diabetes News: Incurable Condition Charcot Foot Explained
Short-term complications of Type 2 diabetes include hypoglycaemia and diabetic ketoacidosis, while long-term complications include how diabetes affects sufferers eyes, heart, kidneys, and nerves and feet. When the condition affects the feet - a condition called neuropathy - the nerves can be severely damaged and can in severe cases result in amputation. Diabetes can cause neuropathy as a result of high blood glucose levels damaging the small blood vessels supplying the nerves, which can prevents essential nutrients reaching the nerves. Neuropathy can affect the sensory nerves - resulting in numbness and the inability to feel pain, which can lead people to avoid injuries which could become infected. The nerve fibres are then damaged or disappear, which can have damaging consequences for the patient. Fri, August 19, 2016 Diabetes is a common life-long health condition. There are 3.5 million people diagnosed with diabetes in the UK and an estimated 500,000 who are living undiagnosed with the condition. People with diabetes that have severely damaged nerves can develop a debilitating bone condition called Charcot foot, where the bones and joints in the foot are weakened. Charcot foot can happens when an injury to the foot causes a broken bone, which may go unnoticed because of the existing neuropathy. The bone then heals abnormally, causing the foot to become misshapen and can cause dislocation and feet to collapse. The only available treatment is a plaster cast to keep the foot immobilised, but healing often doesn’t happen properly, potentially leading to foot deformity and amputation. Dr Nina Petrova, clinical scientist at Kings College London, said: “We don’t have an established medical therapy for this condition. “The only therapy which is well established in cl Continue reading >>
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