What Is The Specific Evidence That Diabetes Type Ii Is Genetic?
As Adriana Heguy noted in Adriana Heguy's answer to What is the specific evidence that diabetes type II is genetic? NIH has released Genetic Factors in Type 2 Diabetes which reads in part In rare forms of diabetes, mutations of one gene can result in disease. However, in type 2 diabetes, many genes are thought to be involved. "Diabetes genes" may show only a subtle variation in the gene sequence, and these variations may be extremely common. The difficulty lies in linking such common gene variations, known as single nucleotide polymorphisms (SNPs), with an increased risk of developing diabetes. This means that while there is a relationship between some genes and Type 2 Diabetes, in the strict sense that your question is phrased, the condition is not heritable in the same sense as eye color, blood type, sickle cell trait, etc. There is no definitive answer to your question in its strictest sense. [The remainder of this answer was first posted as part of the comment thread to Adriana Heguy's answer to What is the specific evidence that diabetes type II is genetic? which included references to 23AndMe.] My understanding is that much of the genetics research to date has been in the ini Continue reading >>