
Neuropathy
A A A Neuropathy What Causes Neuropathy? What Are the Symptoms of Neuropathy? What is Neuropathy Treatment? Are There Home Remedies for Neuropathy? What Medications Are Used to Treat Neuropathy? What Are Neuropathy Medications? Neuropathy is a term that refers to general diseases or malfunctions of the nerves. Nerves at any location in the body can be damaged from injury or disease. Neuropathy is often classified according to the types or location of nerves that are affected. Neuropathy can also be classified according to the disease causing it. (For example, neuropathy from the effects of diabetes is called diabetic neuropathy.) Peripheral neuropathy: Peripheral neuropathy is when the nerve problem affects the nerves outside of the brain and spinal cord. These nerves are part of the peripheral nervous system. Accordingly, peripheral neuropathy is neuropathy that affects the nerves of the extremities- the toes, feet, legs, fingers, hands, and arms. The term proximal neuropathy has been used to refer to nerve damage that specifically causes pain in the shoulders, thighs, hips, or buttocks. Cranial neuropathy: Cranial neuropathy occurs when any of the twelve cranial nerves (nerves that exit from the brain directly) are damaged. Two specific types of cranial neuropathy are optic neuropathy and auditory neuropathy. Optic neuropathy refers to damage or disease of the optic nerve that transmits visual signals from the retina of the eye to the brain. Auditory neuropathy involves the nerve that carries signals from the inner ear to the brain and is responsible for hearing. Autonomic neuropathy: Autonomic neuropathy is damage to the nerves of the involuntary nervous system. These nerves that control the heart and circulation (including blood pressure), digestion, bowel and bladd Continue reading >>

Peripheral Neuropathy Education & Treatment
Peripheral neuropathy describes damage to the peripheral nervous system, which transmits information from the brain and spinal cord to every other part of the body and vice versa. More than 100 types of peripheral neuropathy have been identified, each with its own characteristic set of symptoms, pattern of development, and prognosis. The types of problems perceived by a patient with peripheral neuropathy will depend on the type of nerves — motor, sensory, or autonomic — that are damaged. Some people may experience numbness, tingling, and pricking sensations, sensitivity to touch, or muscle weakness. Others may suffer more extreme symptoms, including burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction. Peripheral neuropathy may be either inherited or acquired. There are numerous causes for peripheral neuropathy including: (trauma) to a nerve, exposure to toxins, autoimmune diseases, nutritional deficiencies (such as Vitamin B12 deficiency), alcoholism, and metabolic disorders (such as diabetes). Acquired peripheral neuropathies are caused by systemic disease, trauma from external agents, or infections or autoimmune disorders affecting nerve tissue. If the specific cause for the neuropathy can be identified then there may be treatment to reverse the symptoms. Inherited forms of peripheral neuropathy are caused by inborn mistakes in the genetic code or by new genetic mutations and at present have no known therapies. Unfortunately at present as many as 50% of all neuropathies will have no identifiable cause. Peripheral Neuropathy Symptoms Peripheral neuropathy is a descriptive term relating to any disease which damages the peripheral nervous system. These nerves transmit information from the brain and spinal cord to every other p Continue reading >>

Understanding Peripheral Neuropathy -- The Basics
What Is Peripheral Neuropathy? The name of the condition tells you a bit about what it is: Peripheral: Beyond (in this case, beyond the brain and the spinal cord.) Neuro-: Related to the nerves -pathy: Disease Peripheral neuropathy refers to the conditions that result when nerves that carry messages to and from the brain and spinal cord from and to the rest of the body are damaged or diseased. The peripheral nerves make up an intricate network that connects the brain and spinal cord to the muscles, skin, and internal organs. Peripheral nerves come out of the spinal cord and are arranged along lines in the body called dermatomes. Typically, damage to a nerve will affect one or more dermatomes, which can be tracked to specific areas of the body. Damage to these nerves interrupts communication between the brain and other parts of the body and can impair muscle movement, prevent normal sensation in the arms and legs, and cause pain. Types of Peripheral Neuropathy There are several different kinds of peripheral neuropathies that stem from a variety of causes. They range from carpal tunnel syndrome (a traumatic injury common after chronic repetitive use of the hands and wrists, such as with computer use) to nerve damage linked to diabetes. As a group, peripheral neuropathies are common, especially among people over the age of 55. All together, the conditions affect 3% to 4% of people in this group. Neuropathies are typically classified according to the problems they cause or what is at the root of the damage. There also are terms that express how extensively the nerves have been damaged. Mononeuropathy Damage to a single peripheral nerve is called mononeuropathy. Physical injury or trauma such as from an accident is the most common cause. Prolonged pressure on a nerve, caused Continue reading >>

Peripheral Neuropathy
What is peripheral neuropathy? Peripheral neuropathy is disorder of nerve(s) apart from the brain and spinal cord. Patients with peripheral neuropathy may have tingling, numbness, unusual sensations, weakness, or burning pain in the affected area. Oftentimes, the symptoms are symmetrical and involve both hands and feet. Because the symptoms are often present in the areas covered by gloves or stockings, peripheral neuropathy is often described as having a “glove and stocking” distribution of symptoms. Peripheral neuropathy can involve different nerve types, including motor, sensory, and autonomic nerves. Peripheral neuropathy can also be categorized by the size of the nerve fibers involved, large or small. Neuropathy can present with many differing symptoms, including numbness, pain of different types, weakness, or loss of balance, depending on the type of nerve involved. Because the autonomic nerves control bodily functions that we do not consciously think of, such as heart rate, digestion, and emptying of the bowel and bladder, autonomic neuropathy manifests with symptoms affecting the loss of control of these functions. Symptoms may include problems with blood pressure, voiding, passage of stools (diarrhea, or constipation), heart rate, or sweating. Cranial neuropathy is similar to peripheral neuropathy, except that the cranial nerves are involved. Any of the cranial nerves can be involved. One of the more common causes of cranial neuropathy is loss of blood flow from the optic artery to the optic nerve, causing ischemic optic neuropathy. Amyloidosis is one of the more common causes of this rare disorder. Specific nerves can be involved in neuropathy. When a specific nerve is involved, the symptoms are limited to the distribution of that nerve. The most commonly i Continue reading >>

Peripheral Neuropathy
Print Overview Peripheral neuropathy, a result of damage to your peripheral nerves, often causes weakness, numbness and pain, usually in your hands and feet. It can also affect other areas of your body. Your peripheral nervous system sends information from your brain and spinal cord (central nervous system) to the rest of your body. Peripheral neuropathy can result from traumatic injuries, infections, metabolic problems, inherited causes and exposure to toxins. One of the most common causes is diabetes mellitus. People with peripheral neuropathy generally describe the pain as stabbing, burning or tingling. In many cases, symptoms improve, especially if caused by a treatable condition. Medications can reduce the pain of peripheral neuropathy. Symptoms Every nerve in your peripheral system has a specific function, so symptoms depend on the type of nerves affected. Nerves are classified into: Sensory nerves that receive sensation, such as temperature, pain, vibration or touch, from the skin Motor nerves that control muscle movement Autonomic nerves that control functions such as blood pressure, heart rate, digestion and bladder Signs and symptoms of peripheral neuropathy might include: Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms Sharp, jabbing, throbbing, freezing or burning pain Extreme sensitivity to touch Lack of coordination and falling Muscle weakness or paralysis if motor nerves are affected If autonomic nerves are affected, signs and symptoms might include: Heat intolerance and altered sweating Bowel, bladder or digestive problems Changes in blood pressure, causing dizziness or lightheadedness Peripheral neuropathy can affect one nerve (mononeuropathy), two or more nerves in different areas Continue reading >>

Is There Any Difference Between Diabetic Neuropathy And Other Forms Of Neuropathy?
The reason I decided to write this article is because I've had many people question the difference. I've even had several people tell me that when they went to their doctor complaining about neuropathy symptoms, the doctor took a blood test and dismissed it as neuropathy because their blood sugars weren't high. The term neuropathy has been strongly associated with Diabetes. Diabetes is a major cause of peripheral neuropathy. Current estimates say that 60-70% of people with diabetes have mild to severe neuropathy. However, it is not the only cause. Neuropathy is nerve damage. Nerve cells are vulnerable to damage from disease or anything that impairs the body’s ability to turn nutrients into energy, to process waste products, to circulate oxygen or to make cellular repair. Diabetes does create the nerve cells vulnerable to damage, but there are many ways in which nerves can get damaged. What are the different ways that someone will get neuropathy? Diabetic neuropathy is a result of prolonged elevated levels of blood glucose. Chemotherapy Neuropathy is caused by damage that is done by the drugs that are attempting to destroy the cancer cells. Alcoholic neuropathy - Alcohol use creates vitamin deficiencies that can lead to nerve damage. Medications – certain drugs have possible side effects of nerve damage (neuropathy). The biggest known drug is the anti-cholesterol drugs since it blocks cholesterol which the nerves need to repair themselves. It can create deficiencies that contribute to nerve damage. Autoimmune Disorders – these are disorders where the body attacks its own cells. If it attacks nerve cells it will create neuropathy. Bacterial and Viral Infections Viruses can attack nerve cells. Bacterial and viral infections can create autoimmune reactions. Pressure o Continue reading >>

Symptoms Of Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy is a condition caused by long-term high blood sugar levels, which causes nerve damage. Some people will not have any symptoms. But for others symptoms may be debilitating. Between 60 and 70 percent of people with diabetes have some form of neuropathy, according to the National Institute of Diabetes and Digestive and Kidney Diseases. Peripheral neuropathy, the most common form of diabetic neuropathy, affects the legs, feet, toes, hands, and arms. Many people do not know that they have diabetes. People unaware of their diabetes may not know what’s causing some of the unusual sensations they’re experiencing. Nerve damage is the result of high levels of blood glucose over long periods of time. It isn’t entirely clear why high glucose levels damage nerves. A number of factors may play a role in nerve fiber damage. One possible component is the intricate interplay between the blood vessels and nerves, according to the Mayo Clinic. Other factors include high blood pressure and cholesterol levels and nerve inflammation. Diabetic peripheral neuropathy usually first appears in the feet and legs, and may occur in the hands and arms later. A common symptom of diabetic peripheral neuropathy is numbness. Sometimes you may be unable to feel your feet while walking. Other times, your hands or feet will tingle or burn. Or it may feel like you’re wearing a sock or glove when you’re not. Sometimes you may experience sudden, sharp pains that feel like an electrical current. Other times, you may feel cramping, like when you’re grasping something like a piece of silverware. You also may sometimes unintentionally drop items you’re holding as a result of diabetic peripheral neuropathy. Walking with a wobbly motion or even losing your balance can res Continue reading >>

Everything You Should Know About Diabetic Neuropathy
What is diabetic neuropathy? Diabetic neuropathy is a serious and common complication of type 1 and type 2 diabetes. It’s a type of nerve damage caused by uncontrolled high blood sugar levels. You may not initially have any symptoms. The condition usually develops slowly, sometimes over the course of several decades. If you have diabetes and are experiencing numbness, tingling, pain, or weakness of your hands or feet, call your doctor. These are the early symptoms of peripheral neuropathy. In cases of severe or prolonged peripheral neuropathy, you may experience injuries or infections in your extremities. In some cases, these can lead to amputation. Damage to other nerves of the body can cause other symptoms. That’s why it’s important to regularly monitor your blood sugar levels and contact your doctor if have any symptoms of neuropathy. It’s common for symptoms of neuropathy to appear gradually. In many cases, the first type of nerve damage to occur involves the nerves of the feet. This can lead to symptoms such as the sensation of pins and needles in your feet. Symptoms vary depending on the nerves affected. Common signs and symptoms of diabetic neuropathy include: sensitivity to touch loss of sense of touch difficulty with coordination when walking numbness or pain in your extremities muscle weakness or wasting nausea and indigestion diarrhea or constipation dizziness upon standing excessive sweating vaginal dryness in women and erectile dysfunction in men Symptoms may vary depending on the type of neuropathy you’re experiencing. The term neuropathy is used to describe several types of nerve damage. In people with diabetes, there are four main types of neuropathy you may develop. Peripheral neuropathy The most common form of neuropathy is peripheral neuropa Continue reading >>

Neuropathy
What is neuropathy? Neuropathy – also called peripheral neuropathy – refers to any condition that affects the normal activity of the nerves of the peripheral nervous system. The peripheral nervous system is the network of nerves that connects the central nervous system – the brain and spinal cord – to the rest of the body. The peripheral nervous system is made up of 3 types of nerves, each with an important role to play in keeping your body healthy and functioning properly. Sensory nerves carry messages from your senses through your spinal cord to your brain. For example, they tell your brain you are touching something hot. Motor nerves travel in the opposite direction. They carry messages from the brain to your muscles. They tell your muscles to move you away from the hot surface. Autonomic nerves are responsible for controlling body functions that occur outside our control, such as breathing, digestion, heart rate, and blood pressure. Neuropathy results when nerve cells, or neurons, are damaged or destroyed. This distorts the way the neurons communicate with each other and with the brain. Neuropathy can affect 1 nerve or nerve type, or a combination of nerves. How common is neuropathy? Neuropathy is very common. It is estimated that about 25% to 30% of Americans will be affected by neuropathy. Neuropathy occurs in 60% to 70% of people with diabetes. Who gets neuropathy? Neuropathy affects people of all ages; however, older people are at increased risk. It is more common in men and in Caucasians. People in certain professions, such as those that require repetitive motions, have a greater chance of developing compression-related neuropathy. What causes neuropathy? There are many causes of neuropathy. The cause can be hereditary (runs in families) or acquired (de Continue reading >>

Types Of Peripheral Neuropathy -
Diabetic Neuropathy Diabetic neuropathy, or nerve damage caused by diabetes, is one of the most common known causes of neuropathy. It is one of many complications associated with diabetes, with nearly 60 percent of diabetics having some form of nerve damage. It is a progressive disease that can involve loss of sensation, as well as pain and weakness, in the feet and sometimes in the hands. Peripheral neuropathy may be more prevalent in people who have difficulty managing their blood sugar levels, have high blood pressure, are overweight, and are over 40 years old. A clinical examination may identify early signs of neuropathy in diabetics without symptoms. The first sign of diabetic neuropathy is usually numbness, tingling or pain in the feet, legs or hands. Over a period of several years, the neuropathy may lead to muscle weakness in the feet and a loss of reflexes, especially around the ankle. As the nerve damage increases, the loss of sensation in the feet can reduce a person's ability to detect temperature or to notice pain. Because the person can no longer notice when his/her feet become injured, people with diabetic neuropathy are more likely to develop foot problems such as skin lesions and ulcers that may become infected. Diabetic neuropathy may suddenly flare up and affect a specific nerve or group of nerves. When this occurs, the result may be weakness and muscle atrophy in various parts of the body, such as involvement of the eye muscles or eyelid (e.g., causing double vision or a drooping eyelid) or thigh muscles. Alternatively, neuropathy caused by diabetes may slowly progress over time. It also can interfere with the normal functioning of the digestive system and sexual organs. SYMPTOMS AND SIGNS (Not all symptoms and signs may be present.) Numbness, tingli Continue reading >>

Peripheral Neuropathy Fact Sheet
What is peripheral neuropathy? How are the peripheral neuropathies classified? What are the symptoms of peripheral nerve damage? What causes peripheral neuropathy? How is peripheral neuropathy diagnosed? What treatments are available? What research is being done? Where can I get more information? What is peripheral neuropathy? An estimated 20 million people in the United States have some form of peripheral neuropathy, a condition that develops as a result of damage to the peripheral nervous system — the vast communications network that transmits information between the central nervous system (the brain and spinal cord) and every other part of the body. (Neuropathy means nerve disease or damage.) Symptoms can range from numbness or tingling, to pricking sensations (paresthesia), or muscle weakness. Areas of the body may become abnormally sensitive leading to an exaggeratedly intense or distorted experience of touch (allodynia). In such cases, pain may occur in response to a stimulus that does not normally provoke pain. Severe symptoms may include burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction. Damage to nerves that supply internal organs may impair digestion, sweating, sexual function, and urination. In the most extreme cases, breathing may become difficult, or organ failure may occur. Peripheral nerves send sensory information back to the brain and spinal cord, such as a message that the feet are cold. Peripheral nerves also carry signals from the brain and spinal cord to the muscles to generate movement. Damage to the peripheral nervous system interferes with these vital connections. Like static on a telephone line, peripheral neuropathy distorts and sometimes interrupts messages between the brain and spinal cord and the Continue reading >>

What Is The Difference Between Peripheral Neuropathy And Complex Regional Pain Syndrome?
What is the Difference between Peripheral Neuropathy and Complex Regional Pain Syndrome? In podiatry, when we talk about peripheral neuropathy we generally are referring to conditions that affect the local nerves in the lower extremity. This is distinct from conditions that affect the brain and/or spinal cord Diabetes is one of the leading causes of peripheral neuropathy. Research shows that diabetes affects the tiny nerves and small arteries in the area where the patient is experiencing pain. The pain is generally described as severe burning or pins and needles and is generally worse at night. Months or years later, this pain may lead to numbness indicating the presence of far greater nerve damage, and in such cases we have to be concerned with the development of ulcerations. Complex regional pain syndrome (CRPS) presents quite differently. Because my practice is focused on patients with severe foot and ankle pain syndromes, I treat people with both peripheral neuropathy and CRPS. Hence, I am well aware of the overt as well as subtle differences between these conditions. People with CRPS generally present with a history of an inciting injury, which may be a sprain, fracture or even surgery (many elective surgical procedures can lead to CRPS). They also present with severe pain, which is far more intense than that experienced by people with peripheral neuropathy. The pain is so severe at times that even air blowing on the area can cause a person to wince in distress. People who have CRPS can also present with other symptoms generally not associated with peripheral neuropathy, such as sleep disturbances and clinical depression. The depression results from the physiology and anatomy of the sympathetic nervous system synapses rather than purely from an emotional reaction Continue reading >>

Peripheral Neuropathy
Peripheral neuropathy is a type of damage to the nervous system. Specifically, it occurs when there is a problem with your peripheral nervous system, the network of nerves that transmits information from your central nervous system (your brain and spinal cord) to the rest of your body. Peripheral Neuropathy: What You Need to Know There are more than 100 types of peripheral neuropathy, each with its own set of symptoms and prognosis. Peripheral neuropathy has many different causes. One of the most common causes of peripheral neuropathy in the U.S. is diabetes. The most common type of peripheral neuropathy is diabetic neuropathy, caused by a high sugar level and resulting in nerve fiber damage in your legs and feet. Symptoms can range from tingling or numbness in a certain body part to more serious effects, such as burning pain or paralysis. Peripheral Neuropathy Causes Peripheral neuropathy has many different causes. The most common causes are metabolic conditions, such as diabetes, and chronic kidney insufficiency or toxicity from alcohol or medications, such as chemotherapy drugs. Some peripheral neuropathy cases are caused by inflammation in nerves, and others are inherited. Diabetes accounts for about half of all causes of peripheral neuropathy cases in the U.S. About 60 to 70 percent of Americans with diabetes have some form of nerve damage. Could Preservatives Prevent Disabling Chemotherapy Side Effect? Johns Hopkins researchers find that common preservative may thwart pain and damage of peripheral neuropathy. Peripheral Neuropathy Types There are more than 100 types of peripheral neuropathy, each with its own set of symptoms and prognosis. To help doctors classify them, they are often broken down into the following categories: Motor neuropathy. This is damage to t Continue reading >>

The Difference Between Pins And Needles And Peripheral Neuropathy
What is the difference between pins and needles and peripheral neuropathy? Most of us have probably experienced the odd feeling of having our hand, leg or foot “fall asleep” which often includes a feeling of numbness or a sensation of pins and needles. This is a very common condition that can happen to just about anyone and is very temporary. It is usually caused when we have sat or slept in an awkward position for too long. Typically, this sensation is caused by too much pressure on the blood vessels that lead to the nerves in that part of the body. Usually, by simply moving the part of the body that has “fallen asleep,” the blood begins to flow more regularly and the sensation subsides. Pins and Needles and Peripheral Neuropathy However, there is a much more serious condition called peripheral neuropathy that has the same symptoms, but often more intense. There are some stark differences between the “pins and needles” feeling that comes from a blocked blood vessel and peripheral neuropathy. One major difference is the frequency and intensity of the sensation that is experienced by those with peripheral neuropathy. Unlike a foot that has fallen asleep, the pins and needles or numbing feeling that those with peripheral neuropathy feel can come at anytime, even when they haven’t been sitting or sleeping in an awkward position. They may feel it at any given time no matter what they are doing. The sensation can last for much longer than just a minute or two. Pins and Needles and Peripheral Neuropathy & Lack of Blood Flow Similar to the “falling asleep” sensation, peripheral neuropathy is caused when nerves in the extremities, including our hands, feet, arms, and legs are not getting an adequate amount of blood and oxygen. However, the cause of this is muc Continue reading >>

Types Of Diabetic Neuropathy
Diabetic neuropathy can be broken into several types. This is because we have different kinds of nerves in our bodies that serve different functions. Your symptoms and treatments depend on which type of diabetic neuropathy you have. There are four types of diabetic neuropathy: Peripheral diabetic neuropathy goes by various names: peripheral diabetic nerve pain and distal polyneuropathy. In this Patient Guide, we’ll refer to it as peripheral diabetic neuropathy, or simply peripheral neuropathy. Peripheral neuropathy is the most common form of neuropathy caused by diabetes. It affects nerves leading to your extremities—to your feet, legs, hands, and arms. The nerves going to your feet are the longest in your body: after they branch off the spinal cord in the lumbar region (low back), they have to go all the way down your legs and into the feet—quite a distance. Because the nerves leading to your feet are so long, it’s most often these nerves that are damaged; there’s more of them to be damaged. This nerve damage can lead to the foot problems often associated with diabetes, including foot deformities, infections, ulcers, and amputations. The article on diabetic neuropathy symptoms will help you learn more about the specific symptoms associated with peripheral diabetic neuropathy. Proximal neuropathy can also be called diabetic amyotrophy. That myo in the word means muscle, so this is a form of neuropathy that can cause muscle weakness. It specifically affects the muscles in the upper part of your leg(s), buttocks, and hips. Sometimes, proximal neuropathy can also involve nerve pain, especially pain that shoots from the low back and down the leg. The technical medical term for that is radiculopathy, although most people refer to it as sciatica. If there’s also s Continue reading >>