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What Can Cause Ketoacidosis Besides Diabetes?

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b

Diabetic Ketoacidosis Without Diabetes.

Abstract CONTEXT: Type B insulin resistance syndrome is a rare disease that occurs due to the development of autoantibodies to the insulin receptor and can result in either severe insulin resistance and hyperglycemia or, conversely, hypoglycemia. Diabetes mellitus is often severe, usually transient, and poorly responsive to exogenous insulin. Diabetic ketoacidosis is an unusual consequence of this most severe form of transient diabetes mellitus. CASE DESCRIPTION: A 39-year-old Nigerian woman presented with significant weight loss, severe diabetic ketoacidosis, and severe insulin resistance requiring massive doses of exogenous insulin. She was diagnosed with systemic lupus erythematosus and type B insulin resistance syndrome. She was treated by immunomodulation with rituximab and pulse dose dexamethasone, and she entered euglycemic remission after 4 months of treatment. She remains independent of exogenous insulin 1 year later on maintenance azathioprine therapy. CONCLUSION: We report a case of severe type B insulin resistance syndrome complicated by severe diabetic ketoacidosis soon after the initial diagnosis of diabetes, despite large doses of exogenous insulin therapy. Our patie Continue reading >>

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  1. imagine

    What type of bread is best?

    I am confused as to which bread to eat, I know processed white is out and it seems that wholegrain is also, so what is the best bread to eat?

  2. Shanghaied Guy

    Originally Posted by imagine
    I am confused as to which bread to eat, I know processed white is out and it seems that wholegrain is also, so what is the best bread to eat? None. Wholegrain has the same amount of carbs.

  3. laserladyofla

    It's hard to say if we don't know where you are. In the US there are low carb breads in many supermarkets. Sometime marketed as "light". You have to read the nutrition labels. The two I can get locally are Sara Lee DeLightful and Rudi's Organic Bakery Right Choice bread. Bread of any type that's not specifically made to be low carb or high fiber will probably not be good. But low carb breads come in white, wheat, and probably others.

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There are now 2 oral drugs used to treat diabetes in a new class called SGLT 2 inhibitors. They are Invokana and Farxiga. These pills block an enzyme in the kidney and result in sugar being spilled into the urine. This can account for 150-300 calories lost in the urine per day. In addition to lowering blood sugar, theyhave a diuretic effect, and can lower blood pressure. There has been some concern that these drugs may be associated with bladder cancer. The problem is that it is well established that diabetics have a higher risk of MANY cancers including pancreas, liver, colon, kidney and bladder. Diabetics take diabetic drugs, and non-diabetics don't. A reasonable comparison would be to note that people who take cholesterol drugs have more heart attacks than those that do not. Obviously, young healthy people with normal cholesterol do not take these drugs, and high risk older people with high cholesterol do. You are selecting out a group of people that inherently are at higher risk for certain diseases. That said, I have now tried these medications in the office, and am seeing significant weight loss AND improvement in blood pressure. I have tried them on non-diabetics, and they s

Fda Issues Safety Statement That Sglt-2 Inhibitors May Cause Diabetic Ketoacidosis

Twitter Summary: @US_FDA warns SGLT-2 inhibitors may cause DKA in some patients w/out #hyperglycemia. Get the inside scoop from Dr. Anne Peters. Essential news for patients, caregivers, and health care providers: the FDA recently issued a drug safety warning on the possibility of diabetic ketoacidosis (DKA) in all people taking SGLT-2 inhibitor pills. Diabetic ketoacidosis is a complication of diabetes that occurs when the body produces elevated levels of acidic compounds called ketones, often due to a lack of effective insulin action, which can lead to hospitalization, coma, and even death if left untreated. Typically, diabetic ketoacidosis is associated with extremely high blood glucose levels (hyperglycemia), but the reports of diabetic ketoacidosis associated with SGLT-2 inhibitors come without these elevations in blood glucose – this is called “euglycemic diabetic ketoacidosis” or “euDKA.” It is considered an acute complication of type 1 diabetes and does not generally occur in people with type 2 diabetes. The FDA’s safety warning is currently based on 20 reported cases of euglycemic ketoacidosis when using SGLT-2 inhibitors in people who had mostly been diagnosed Continue reading >>

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  1. MEGriff1950

    Average GB equals A1C

    I found this and thought I would share.
    http://www.rajeun.net/HbA1c_glucose.html
    Hb-A1c 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9
    mg/dl 65 69 72 76 79 83 86 90 93 97
    mmol/l 3.6 3.8 4.0 4.2 4.4 4.6 4.8 5.0 5.2 5.4
    Hb-A1c 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8 5.9
    mg/dl 101 104 108 111 115 118 122 126 129 133
    mmol/l 5.6 5.8 6.0 6.2 6.4 6.6 6.8 7.0 7.2 7.4
    Hb-A1c 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 6.9
    mg/dl 136 140 143 147 151 154 158 161 165 168
    mmol/l 7.6 7.8 8.0 8.2 8.4 8.6 8.8 9.0 9.2 9.4
    Hb-A1c 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9
    mg/dl 172 176 180 183 186 190 193 197 200 204
    mmol/l 9.6 9.8 10.0 10.2 10.4 10.6 10.8 11.0 11.2 11.4
    Hb-A1c 8.0 8.1 8.2 8.3 8.4 8.5 8.6 8.7 8.8 8.9
    mg/dl 207 211 215 218 222 225 229 232 236 240
    mmol/l 11.6 11.8 12.0 12.2 12.4 12.6 12.8 13.0 13.2 13.4
    Hb-A1c 9.0 9.5 10.0 10.5 11.0 11.5 12.0 12.5 13.0 13.5
    mg/dl 243 261 279 297 314 332 350 368 386 403
    mmol/l 13.6 14.6 15.6 16.6 17.5 18.5 19.5 20.4 21.4 22.4
    Color Key: Optimal Good High Bad Terrible Horrible Deathly Suicidal Suicidal Suicidal
    This is an old table with a new twist: the color code expresses an opinion… MY OPINION. ("Green" is good, but "orange" and "red" and "bright red" and "blood red" are progressively worse!)
    4.0% to 4.6% A+ (Excellent)
    4.7% to 4.9% A (Excellent)
    5.0% to 5.2% B (O.K.)
    5.3% to 5.4% C (Bad)
    5.5% to 5.9% C- (Bad)
    6.0% to 6.4% D (Very Bad)
    6.5% to 6.9% D- (Very Bad)
    7.0% or more F (Failure)

  2. kdroberts

    I wouldn't pay a whole lot of attention to charts that give you an A1c to BG average. Since A1c doesn't measure blood sugar and the part blood sugar plays into the result is different for each person, the estimates can be very wrong and usually discouraging.

  3. annesmith

    This is very very true. When my A1c has been 5.9, my numbers were approx 55, 600, 200,86,51,500,90,81,444,200,61, 86, 81, 500, 400, 73,71, 80,100,186,182,600,330,58. I think it's great to have an average, but it means SO many different things I have discovered…ANNE

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Definition Diabetic ketoacidosis (DKA) results from dehydration during a state of relative insulin deficiency, associated with high blood levels of sugar level and organic acids called ketones. Diabetic ketoacidosis is associated with significant disturbances of the body's chemistry, which resolve with proper therapy. Symptoms A person developing diabetic ketoacidosis may have one or more of these symptoms: - Excessive thirst or drinking lots of fluid - Frequent urination - General weakness - Vomiting - Loss of appetite - Confusion - Abdominal pain - Shortness of breath - A generally ill appearance - Dry skin - Dry mouth - Increased heart rate - Low blood pressure - Increased rate of breathing - A distinctive fruity odor on the breath Causes Diabetic ketoacidosis occurs when a person with diabetes becomes dehydrated. As the body produces a stress response, hormones (unopposed by insulin due to the insulin deficiency) begin to break down muscle, fat, and liver cells into glucose (sugar) and fatty acids for use as fuel. These hormones include glucagon, growth hormone, and adrenaline. Prevention - Keep taking your insulin it's very important not to stop treatment when you're ill; you

Diabetic Ketoacidosis – Its Causes And Its Treatments

Certified diabetes educator Becky Wells recently retired from working with a diabetes self-management education program at Hendrick Medical Center in Abilene, Texas. She provides advice on diabetes for Insulin Nation. Question: What is diabetic ketoacidosis and how can I prevent it? Answer: Diabetic ketoacidosis (DKA) is a possible complication of diabetes that can cause kidney damage and may prove fatal if left untreated. It is more common with Type 1 diabetes than with Type 2 diabetes, and many with Type 1 are experiencing DKA when first diagnosed with Type 1. The condition results from an insulin deficiency that may have come about from undiagnosed diabetes, a forgotten insulin injection, a malfunctioning insulin pump, an illness, psychological stress, an eating disorder, or insulin that was incorrectly stored. In ketoacidosis, a lack of insulin causes the body to go into starvation mode. This is because insulin is necessary for glucose to enter most of the body’s cells. The body instead tries to get energy for its processes by breaking down fatty acids. With this breakdown, ketones are formed in the bloodstream, and this causes a decrease in the blood’s pH levels. Without e Continue reading >>

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  1. twodoor2

    Well, someone mentioned you could reuse the reservoirs, so I thought I would save myself a step every 3 days, and reuse one. I filled the reservoir up twice as full, and after three days (or 2.5 days actually), I reused the reservoir for the next site change.
    Then after a mid-day snack, she was hanging in the mid to upper 200's., it seemed like she was getting some insulin since she would be 500+ with the food she was eating. I thought I could correct at dinner, but it was as if no correction dose was getting her down, she might as well have been injected with water. She would even climb higher after the DIA was over. Nothing worked, adding more temp basals, corrections, nada!! Then I decided to finally give her a syringe dose, and she went from 284 to 147 in the span of 2 hours - FINALLY.
    Her site was due for a change in 1.5 days, but I changed it this morning. She takes Lantus, so I didn't have to change it right away after her syringe correction.
    I suspect that there were some gaps in the reservoir rubber where the lubricant is. I was reading that this causes highs. I'm not sure. Today will bring a new story - perpaps it is that she needs major adjustments, but I find it suspicious since the half unit of syringe insulin brought her right where it should have.
    Does anyone reuse the MM reservoirs, and if so, do they have this problem? I did prime, and she does wear the sure-t's so it's doubtful it's a needle failure.

  2. BrendaK

    Our endo in Michigan told us that since the pump is worn close to the body the insulin heats up more. He told us it was really important to change the insulin cartridge every 3 days because the insulin will heat up (because of body temperature) and go bad. He even said it the summer you need to change it every 2 days, just so the insulin won't go bad.
    I've also heard some people say that the plastic from the cartridge reacts somehow with the insulin so it's not good for a long time, meaning you shouldn't prefill the cartridges.
    Hmmmmm....I wonder what other's responses will be.

  3. PixieStix

    My son doesn't typically have too many highs, but usually they will start to happen on Day 3 and the correction boluses seem less effective to lower them too. I personally think he would do better to change his entire set out every 2 days, but he has not been too excited by this suggestion so we aim for 3 days but change it out as soon as the unexpected highs begin. I would recommend just changing out the whole set, including the reservoir, every 3 days.

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