diabetestalk.net

What Are The Side Effects Of Januvia

Important Safety Information

Important Safety Information

WHAT IS JANUVIA®? JANUVIA (jah-NEW-vee-ah) is a once-daily prescription pill that, along with diet and exercise, helps lower blood sugar levels in adults with type 2 diabetes. JANUVIA should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while taking JANUVIA. Serious side effects can happen in people who take JANUVIA, including pancreatitis, which may be severe and lead to death. Before you start taking JANUVIA, tell your doctor if you've ever had pancreatitis. Stop taking JANUVIA and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis. Before you start taking JANUVIA, tell your doctor if you have ever had heart failure (your heart does not pump blood well enough) or have problems with your kidneys. Contact your doctor right away if you have increasing shortness of breath or trouble breathing (especially when you lie down); swelling or fluid retention (especially in the feet, ankles, or legs); an unusually fast increase in weight; or unusual tiredness. These may be symptoms of heart failure. Do not take JANUVIA if you are allergic to any of its ingredients, including sitagliptin. Symptoms of serious allergic reactions to JANUVIA, including rash, hives, and swelling of the face, lips, tongue, and throat that may cause difficulty breathing or swallowing, can occur. If you have any symptoms of a serious allergic reaction, stop taking JANUVIA and call your doctor right away. Kid Continue reading >>

Januvia Side Effects

Januvia Side Effects

Januvia and the similar drug Janumet are two medications made by Merck to treat type 2 diabetes along with diet and exercise changes. Merck got these two drugs approved by the U.S. Food and Drug Administration (FDA) in 2006 and 2007 and since then has made a huge amount of money. Drugs like these have been so popular because more and more people in the U.S. are struggling with Type 2 diabetes. Medications may be helpful for lowering blood sugar in patients with this chronic condition, but they come with risks. Januvia side effects range from infections to acute pancreatitis and even pancreatic cancer. As the risks and how serious they are become clearer, more people are blaming Merck for not warning them of the side effects that were possible with their drugs. These people are also suing the company seeking compensation for the damage they have suffered to their health. How Januvia and Janumet Work Januvia is the generic drug sitagliptin, while Janumet is a combination of sitagliptin and metformin. Merck developed sitagliptin to control high blood sugar in people with Type 2 diabetes. This is a chronic condition, typically caused by a poor diet and obesity. It is characterized by chronically high blood sugar levels. This happens when the body becomes less sensitive to insulin, the hormone that is supposed to lower blood sugar levels. Someone with Type 2 diabetes may also be producing less insulin from the pancreas. Having blood sugar levels that are too high for a long period of time leads to serious health consequences, and ultimately to death. This is why it is so crucial for people with Type 2 diabetes to get their blood sugar under control. Drug companies have produced a number of drugs to do this in recent years as cases of the condition rise in the population. Lik Continue reading >>

Januvia

Januvia

Januvia is a prescription medication used to lower blood sugar levels in adult patients with type 2 diabetes. Januvia belongs to a group of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, which help lower blood sugar levels in two ways. It helps the body increase insulin to stabilize blood sugar and decrease sugars that are made in the liver. This medication comes in tablet form and is taken once a day, with or without food. Common side effects include upper respiratory infection, stuffy nose, sore throat, nausea, and diarrhea. Januvia is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Pancreatitis. Serious side effects have occurred with Januvia use including inflammation of the pancreas (pancreatitis) which may be severe and lead to death. Stop taking Januvia and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. Low blood sugar (hypoglycemia). If you take Januvia with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use Januvia. Signs and symptoms of low blood sugar may include: headache drowsiness weakness dizziness confusion irritability hunger fast heart beat sweating feeling jittery Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking Januvia and call your doctor right away. Your doctor may give you a medicine for y Continue reading >>

Januvia And Janumet

Januvia And Janumet

Januvia (sitagliptin) is an oral Type 2 diabetes medication manufactured by Merck & Co. The U.S. Food and Drug Administration (FDA) approved the drug in 2006, and it is one of the most popular Type 2 diabetes drugs on the market. In 2007, the FDA approved a variation of Januvia called Janumet, which is a combination of sitagliptin and metformin. Janumet also comes in an extended-release formula called Janumet XR. Januvia and Janumet are known as dipeptidyl peptidase 4 (DPP-4) inhibitors that work by helping the body produce more insulin. Both Januvia and Janumet belong to a class of drugs called dipeptidyl peptidase 4 (DPP-4) inhibitors that work by helping the body produce more insulin. Januvia was the first DPP-4 approved by the FDA and is the top-selling brand in its class. Two million prescriptions were written for Januvia in 2011. Januvia brought in about $6 billion in 2014. Merck stands to benefit from the patent on the drug until 2022. In clinical trials, Januvia proved effective in controlling blood-sugar levels. However, some studies reported rare and serious side effects, including acute pancreatitis, severe joint pain, pancreatic cancer and thyroid cancer. How Do Januvia and Janumet Work? Januvia is designed to work with other Type 2 diabetes medications, like Byetta, to increase their effectiveness. It helps lower blood sugar in two ways. It helps the body increase insulin to stabilize blood sugar and decrease sugars that are made in the liver. It is a part of the class of diabetes medications called DPP-4 inhibitors. DPP-4 is a protein made by the body that plays a role in glucose metabolism. The process works like this: After a person eats and blood sugar rises, intestinal cells release hormones called incretin hormones. Incretin stimulates pancreatic cell Continue reading >>

Januvia

Januvia

are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis. Your healthcare provider should do blood tests to check how well your kidneys are working before and during your treatment with FARXIGA Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at a higher risk of dehydration if you have low blood pressure; take medicines to lower your blood pressure, including water pills (diuretics); are 65 years of age or older; are on a low salt diet, or have kidney problems Ketoacidosis occurred in people with type 1 and type 2 diabetes during treatment with FARXIGA. Ketoacidosis is a serious condition which may require hospitalization and may lead to death. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL Kidney problems. Sudden kidney injury occurred in people taking FARXIGA. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections (UTI), some that lead to hospitalization, occu Continue reading >>

What Are The Possible Side Effects Of Sitagliptin (januvia)?

What Are The Possible Side Effects Of Sitagliptin (januvia)?

A A A Medications and Drugs Brand Names: Januvia Generic Name: sitagliptin (Pronunciation: SI ta glip tin) What is sitagliptin (Januvia)? Sitagliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Sitagliptin is for people with type 2 diabetes. Sitagliptin is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Sitagliptin may also be used for purposes not listed in this medication guide. What are the possible side effects of sitagliptin (Januvia)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking sitagliptin and call your doctor at once if you have a serious side effect such as: pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate; or urinating less than usual or not at all; swelling, weight gain, feeling short of breath; or severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Less serious side effects may include: runny or stuffy nose, sore throat; headache, back pain, joint or muscle pain; or This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about sitagliptin (Januvia)? Do not use this medication if you are allergic to sitagliptin or if you are in a state of diabetic ketoa Continue reading >>

Sitagliptin; Januvia

Sitagliptin; Januvia

are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis. Your healthcare provider should do blood tests to check how well your kidneys are working before and during your treatment with FARXIGA Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at a higher risk of dehydration if you have low blood pressure; take medicines to lower your blood pressure, including water pills (diuretics); are 65 years of age or older; are on a low salt diet, or have kidney problems Ketoacidosis occurred in people with type 1 and type 2 diabetes during treatment with FARXIGA. Ketoacidosis is a serious condition which may require hospitalization and may lead to death. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL Kidney problems. Sudden kidney injury occurred in people taking FARXIGA. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections (UTI), some that lead to hospitalization, occu Continue reading >>

Januvia Deemed Safe For People With Type 2 Diabetes At Risk Of Heart Problems, Study Says

Januvia Deemed Safe For People With Type 2 Diabetes At Risk Of Heart Problems, Study Says

Januvia deemed safe for people with type 2 diabetes at risk of heart problems, study says Januvia deemed safe for people with type 2 diabetes at risk of heart problems, study says Link found between higher mole count and increased type 2 diabetes risk 06 January 2017 A commonly prescribed drug to treat type 2 diabetes drug called Januvia (sitagliptin) is safe for use in older people who may be at risk of cardiovascular problems, a study reports. People with type 2 diabetes are more prone to suffer from cardiovascular problems because of an increased risk of high blood pressure , heart disease and stroke . In this new analysis, researchers at the Oxford Centre for Diabetes found sitagliptin, a relatively new drug, raised "no significant safety concerns" in people with type 2 diabetes . The study, entitled TECOS (Trial Evaluating Cardiovascular Outcomes With Sitagliptin), collected data from more than 14,000 people aged 50 years or over who had type 2 diabetes and a history of cardiovascular problems. The researchers focused on 14 per cent of the participants who were aged 75 and in the oldest age group. The group had HbA1c levels of at least 6.5% but not higher than 8%. "Among older patients with well-controlled type 2 diabetes and cardiovascular disease, sitagliptin had neutral effects on cardiovascular risk and raised no significant safety concerns," said the authors. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor which helps to increase insulin in the body by decreasing the amount of sugar. It is usually taken alongside a healthy diet and regular exercise , and can be used alongside other type 2 diabetes drugs such as metformin . Cardiovascular disease is caused when blood vessels are damaged which can be caused by smoking , high sugar levels or unbalanced Continue reading >>

Januvia Smackdown

Januvia Smackdown

Get your ringside seats, Folks! A while back I posted about the Merck's new Type 2 oral drug Januvia (What It Doesn't Do), explaining how it apparently trumps competitors in terms of patient "tolerability." No other post has ever generated such ongoing reader energy, both positive and negative. Nearly every day, several new commentors weigh in, duking it out over the relative merits of Januvia. Most everyone seems to agree that Januvia reduces appetite, which is a good thing. But then again, Byetta is known for that effect as well. The key is question whether Januvia fulfills its core function of lowering blood glucose (BG) levels, and lives up to its no-side-effects promise. As of today, the score stands pretty much tied, as such: Total comments = 50 Positive = 10 Negative = 13 Mixed = 16 (liked some aspects of the drug but not others) Neutral = 11 (those asking or responding to questions only) Among the most vocal of the Pro Team: "I take Januvia and have for 6 months. I have no side effects. I have experienced a decrease in appetite. I have had no headaches or respiratory problems. My BG has gone down. It is a great drug." -- Mike "Januvia has been a positive thing for me. My sugar levels dropped from 240+ to 110 +/- 10 after fasting. I have taken 100 mg once per day for a month... I am not as hungry as before usage." -- Jim K. L. "I've been on Januvia for a little over three months and have lost over 15 pounds which I had put on with Actos. I've experienced no side effects, other than I am not hungry all of the time. For me it has been very effective..." -- Bill "I am substantially less hungry then I have felt in years ... and my BG hovers around 100 - 120 between meals/fasting, and 120 - 160 for a few hours after a heavy carb meal. The usual BG spikes of 180 - 200+ Continue reading >>

Januvia Side Effects Center

Januvia Side Effects Center

Januvia (sitagliptin) is an oral diabetes medicine for people with type 2 diabetes (non-insulin-dependent) diabetes. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Many people using Januvia do not have serious side effects. Side effects that may occur with Januvia include: headache, joint or muscle pain, nausea, stomach pain, diarrhea, or constipation. Although Januvia by itself usually does not cause low blood sugar (hypoglycemia), low blood sugar may occur if Januvia is prescribed with other anti-diabetic medications. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Tell your doctor if you have serious side effects of Januvia including pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate), urinating less than usual or not at all, swelling, weight gain, shortness of breath, or severe skin reaction (fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads [especially in the face or upper body] and causes blistering and peeling). The recommended dose of Januvia is 100 mg once daily. Januvia may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy Januvia should be used only when prescribed. Pregnancy may cause or worsen diabetes. Your doctor may change your diabetes treatment during pregnancy. It is unknown if this drug passes into breast milk. Cons Continue reading >>

Januvia

Januvia

How does this medication work? What will it do for me? Sitagliptin belongs to the group of diabetes medications called DPP-4 inhibitors. It works by increasing the amount of incretin released by the intestine. Incretin is a hormone that raises insulin levels when blood sugar is high and decreases the amount of sugar made by the body. Sitagliptin is used alone or in combination with other medications to improve blood sugar levels in adults with type 2 diabetes. This medication should be used as part of an overall diabetes management plan that includes a diet and exercise program. This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. What form(s) does this medication come in? 25 mg Each pink, round, film-coated tablet, with "221" on one side, contains 25 mg sitagliptin. Nonmedicinal ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate (calcium hydrogen phosphate, anhydrous), croscarmellose sodium, magnesium stearate, and sodium stearyl fumarate; film coating: polyvinyl alcohol, polyethylene gl Continue reading >>

Januvia Side Effects By Likelihood And Severity

Januvia Side Effects By Likelihood And Severity

are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis. Your healthcare provider should do blood tests to check how well your kidneys are working before and during your treatment with FARXIGA Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at a higher risk of dehydration if you have low blood pressure; take medicines to lower your blood pressure, including water pills (diuretics); are 65 years of age or older; are on a low salt diet, or have kidney problems Ketoacidosis occurred in people with type 1 and type 2 diabetes during treatment with FARXIGA. Ketoacidosis is a serious condition which may require hospitalization and may lead to death. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL Kidney problems. Sudden kidney injury occurred in people taking FARXIGA. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections (UTI), some that lead to hospitalization, occu Continue reading >>

Januvia Side Effects

Januvia Side Effects

Januvia is the brand name of the drug sitagliptin, which is used to treat type 2 diabetes. Type 2 diabetes is a disease in which the body doesn't make or use the hormone insulin normally, so it can't properly control your blood sugar levels. Januvia belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing levels of substances in the body that help lower blood sugar. Januvia may be taken alone or with other diabetes medications. It's often prescribed as a combination medicine called Janumet (which contains the drugs sitagliptin and metformin). Taking Januvia, along with adopting a healthy lifestyle, can reduce your risk of developing serious or life-threatening complications from diabetes, which may include heart disease, stroke, nerve damage, kidney problems, or eye problems. The U.S. Food and Drug Administration (FDA) approved Januvia in 2006. It's manufactured by Merck & Co. Januvia Warnings Januvia shouldn't be taken by people with type 1 diabetes (a disease in which the body doesn't produce any insulin) or diabetic ketoacidosis (a dangerous condition that can occur if high blood sugar is untreated). Before taking Januvia, tell your doctor if you have, or have ever had: Kidney disease Angioedema (swelling of the face, lips, tongue, throat, arms, or legs) Januvia may increase the risk of developing pancreatitis (swelling and inflammation of the pancreas). Be sure to tell your doctor if you've ever had any problems with your pancreas, or if you experience any of the following symptoms while taking Januvia: Severe pain in your upper stomach that spreads to your back Loss of appetite Fast heartbeat Severe nausea and vomiting Also, tell your doctor you're taking this medicine before having any type of surgery, including a dental Continue reading >>

Sitagliptin For Diabetes Januvia

Sitagliptin For Diabetes Januvia

Take sitagliptin tablets once a day. Remember to follow any advice you have been given about your diet. The most common side-effects are feeling sick (nausea), headache, and nose or throat infections. About sitagliptin Type of medicine An antidiabetic medicine Used for Adults with type 2 diabetes mellitus Also called Januvia®; Janumet® (a combination tablet containing sitagliptin with metformin) Available as Tablets Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called sugar diabetes (diabetes mellitus). People with diabetes need treatment to control the amount of sugar (glucose) in their blood. This is because good control of blood glucose levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like sitagliptin are given alongside the changes in diet. Sitagliptin works in part by increasing the amount of insulin produced by your body. It also reduces the amount of a substance called glucagon being produced by your pancreas. Glucagon causes your liver to produce more sugar, so by reducing the amount of glucagon in your body, this also helps to reduce the levels of glucose in your blood. Before taking sitagliptin Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking sitagliptin it is important that your doctor knows: If you are pregnant, trying for a baby or breast-feeding. If you have any problems with the way your kidneys w Continue reading >>

Januvia Side Effects

Januvia Side Effects

Generic Name: sitagliptin Note: This document contains side effect information about sitagliptin. Some of the dosage forms listed on this page may not apply to the brand name Januvia. For the Consumer Applies to sitagliptin: oral tablet Along with its needed effects, sitagliptin (the active ingredient contained in Januvia) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking sitagliptin: Less common Anxiety blurred vision chills cold sweats confusion cool, pale skin depression dizziness fast heartbeat headache increased hunger loss of consciousness nausea nightmares seizures shakiness slurred speech unusual tiredness or weakness Incidence not known Blistering, peeling, loosening of the skin diarrhea hives or welts, itching, or skin rash large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs loss of appetite pains in the stomach, side, or abdomen, possibly radiating to the back puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue red skin lesions, often with a purple center redness of the skin severe joint pain sores, ulcers, or white spots in the mouth or on the lips vomiting Some side effects of sitagliptin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Body aches Continue reading >>

More in diabetes