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What Are The Side Effects From Metformin?

Metformin Side Effects And How To Deal With Them

Metformin Side Effects And How To Deal With Them

Metformin side effects include diabetic neuropathy, brain fog, and digestive issues. You can address them through diet, Vitamin B12, CoQ10, and exercise. Let us understand the drug Metformin in detail and study different forms of metformin, its uses and common metformin side effects along with how to deal with them. Metformin: What Is It Used For? Metformin is an old warhorse in the pharma battle against diabetes. It has been the mainstay in the treatment of Type 2 Diabetes for more than fifty years, often matching or outperforming newer drugs. In fact, many new combination drugs are often created with metformin as one of the main ingredients. Thanks to its long run in the pharmaceutical world, the side effects of Metformin are also well known. The Metformin-PCOS connection has been studied extensively since a majority of health complications associated with PCOS (polycystic ovarian syndrome) are due to hyperinsulinemia (high amounts of insulin in the blood stream). Metformin is known to reduce circulating insulin levels. The use of this drug in women with PCOS has shown highly encouraging results. RELATED: 10 Easy Breakfast Ideas For Diabetics Most Prescribed Names in Metformin Category Include: Fortamet: It is an extended-release formulation that contains metformin hydrochloride. The tablets are designed for once-a-day administration. They deliver either 500 mg or 1000 mg of metformin. The tablet is made using a patented technology called SCOTTM that delivers the active compound slowly and at a constant rate. Glucophage: Glucophage tablets contain metformin hydrochoride. They contain either 500 mg, 850 mg or 1000 mg of the active compound. Glucophage tablets do not contain any special covering and need to be taken multiple times a day until the prescribed dosage is me Continue reading >>

What Are The Possible Side Effects Of Metformin?

What Are The Possible Side Effects Of Metformin?

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with metformin. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect. Very common (affect more than 1 in 10 people) Disturbances of the gut such as nausea, vomiting, diarrhoea or abdominal pain. Loss of appetite. The above side effects are most likely to occur when you first start taking metformin and tend to improve over time. They can be prevented or minimised by taking the medicine during or after meals, and by increasing the dose gradually when treatment is started. Follow the instructions given by your doctor. Common (affect between 1 in 10 and 1 in 100 people) Taste disturbance, usually a metallic taste. Very rare (affect fewer than 1 in 10,000 people) Lactic acidosis - a potentially serious condition where there is too much acid in the blood. Symptoms may include breathing difficulties and non-specific symptoms such as feeling weak, sick or generally unwell, vomiting, abdominal pain, or unusual muscle pains or discomfort. It's important to consult your doctor straight away if you experience these symptoms. Kidney problems, dehydration, prolonged fasting and drinking excessive amounts of alcohol increase the risk. Skin reactions such as rash, itching or flushing. If you want any more information about the possible side effects of metformin you should talk to your doctor or pharmacist, or read the leaflet that comes with the medicine. If you think you have experienced a side effect, did you know you can report this using the yellow card website? Last updated: 16/06/2016 Continue reading >>

Diabetes Drugs: Metformin

Diabetes Drugs: Metformin

Editor’s Note: This is the second post in our miniseries about diabetes drugs. Tune in on August 21 for the next installment. Metformin (brand names Glucophage, Glucophage XR, Riomet, Fortamet, Glumetza) is a member of a class of medicines known as biguanides. This type of medicine was first introduced into clinical practice in the 1950’s with a drug called phenformin. Unfortunately, phenformin was found to be associated with lactic acidosis, a serious and often fatal condition, and was removed from the U.S. market in 1977. This situation most likely slowed the approval of metformin, which was not used in the U.S. until 1995. (By comparison, metformin has been used in Europe since the 1960’s.) The U.S. Food and Drug Administration (FDA) required large safety studies of metformin, the results of which demonstrated that the development of lactic acidosis as a result of metformin therapy is very rare. (A finding that has been confirmed in many other clinical trials to date.) Of note, the FDA officer involved in removing phenformin from the market recently wrote an article highlighting the safety of metformin. Metformin works primarily by decreasing the amount of glucose made by the liver. It does this by activating a protein known as AMP-activated protein kinase, or AMPK. This protein acts much like an “energy sensor,” setting off cellular activities that result in glucose storage, enhanced entry of glucose into cells, and decreased creation of fatty acids and cholesterol. A secondary effect of the enhanced entry of glucose into cells is improved glucose uptake and increased storage of glycogen (a form of glucose) by the muscles. Additionally, the decrease in fatty acid levels brought about by metformin may indirectly improve insulin resistance and beta cell func Continue reading >>

Metformin

Metformin

Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Tell your doctor if you have kidney disease. Your doctor will probably tell you not to take metformin. Also, tell your doctor if you are over 65 years old and if you have ever had a heart attack; stroke; diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment); a coma; or heart or liver disease. Taking certain other medications with metformin may increase the risk of lactic acidosis. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran). Tell your doctor if you have recently had any of the following conditions, or if you develop them during treatment: serious infection; severe diarrhea, vomiting, or fever; or if you drink much less fluid than usual for any reason. You may have to stop taking metformin until you recover. If you are having surgery, including dental surgery, or any major medical procedure, tell the doctor that you are taking metformin. Also, tell your doctor if you plan to have any x-ray procedure in which dye is injected, especially if you drink or have ever drunk large amounts of alcohol or have or have had liver disease or heart failure. You may need to stop taking metformin before the procedure and wait 48 hours to restart treatment. Your doctor will tell you exactly when you should stop taking metformin and when you should start taking it again. If you experience any of the following symptoms, stop taking metformin and call your doctor immediately: extreme tiredness, weakness, or discomfort; nausea; vomiting; stomach pain; decreased appetite; deep and rapid breathing or shortness of breath; dizzi Continue reading >>

Side Effects Of Metformin: What You Should Know

Side Effects Of Metformin: What You Should Know

Metformin is a prescription drug used to treat type 2 diabetes. It belongs to a class of medications called biguanides. People with type 2 diabetes have blood sugar (glucose) levels that rise higher than normal. Metformin doesn’t cure diabetes. Instead, it helps lower your blood sugar levels to a safe range. Metformin needs to be taken long-term. This may make you wonder what side effects it can cause. Metformin can cause mild and serious side effects, which are the same in men and women. Here’s what you need to know about these side effects and when you should call your doctor. Find out: Can metformin be used to treat type 1 diabetes? » Metformin causes some common side effects. These can occur when you first start taking metformin, but usually go away over time. Tell your doctor if any of these symptoms are severe or cause a problem for you. The more common side effects of metformin include: heartburn stomach pain nausea or vomiting bloating gas diarrhea constipation weight loss headache unpleasant metallic taste in mouth Lactic acidosis The most serious side effect metformin can cause is lactic acidosis. In fact, metformin has a boxed warning about this risk. A boxed warning is the most severe warning from the Food and Drug Administration (FDA). Lactic acidosis is a rare but serious problem that can occur due to a buildup of metformin in your body. It’s a medical emergency that must be treated right away in the hospital. See Precautions for factors that raise your risk of lactic acidosis. Call your doctor right away if you have any of the following symptoms of lactic acidosis. If you have trouble breathing, call 911 right away or go to the nearest emergency room. extreme tiredness weakness decreased appetite nausea vomiting trouble breathing dizziness lighthea Continue reading >>

Metformin Side Effects

Metformin Side Effects

Metformin is the generic name of the prescription medications Glucophage, Glumetza, and Fortamet, used to control blood sugar in people with type 2 diabetes. Type 2 diabetes is a disease that occurs when the body does not produce or use insulin normally, which results in high blood sugar (glucose). Metformin works by decreasing the amount of sugar you absorb from food and reducing the amount of glucose your liver makes. It also increases your body's response to insulin. Metformin is in a class of medications called biguanides. It's sometimes used along with diet, exercise, and other medications to control blood glucose levels. It's also used to prevent the development of diabetes in people at high risk for the disease, treat polycystic ovary syndrome (PCOS), and control weight gain that occurs from taking certain drugs. The Food and Drug Administration (FDA) approved the medication in 1994. Metformin and PCOS (Polycystic Ovary Syndrome) Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects about one in 10 women of reproductive age. Women with PCOS may have enlarged ovaries containing fluid, or follicles. These fluids may cause infrequent or prolonged menstrual periods, excess hair growth, acne, and weight gain. The exact cause of PCOS is unknown, but the disorder has been linked to insulin resistance and excess insulin in the body. If you have insulin resistance, your body cannot use insulin effectively. As a result, your pancreas has to secrete more insulin to make glucose available to cells and tissues, including those that compose the ovaries. Researchers believe excess insulin may affect the ovaries by increasing androgen production, which may interfere with the ovaries' ability to ovulate. Because metformin can increase your body’s response Continue reading >>

The Multiple Benefits Of Metformin

The Multiple Benefits Of Metformin

Metformin (brand name "Glucophage") has been used in the treatment of type II diabetes for the past 40 years.1 This drug counteracts many of the underlying factors that result in the manifestation of this insidious disease. Metformin also produces helpful side benefits that can protect against the lethal complications of type II diabetes. Frequently prescribed anti-diabetic drugs fail to address the fundamental causes of type II diabetes and can induce serious side effects. Type II diabetes affects between 16 to 19 million Americans. About 75% of type II diabetics will die from a cardiovascular-related disease. Conventional doctors often prescribe drugs for the purpose of lowering blood sugar levels. These drugs do not adequately address the multiple underlying pathologies associated with the type II diabetic state. Type II diabetes is characterized by cellular insulin resistence. The result is excess accumulation of glucose in the bloodstream as cells become resistant to the effects of insulin. Type II diabetes is characterized by cellular insulin resistence. The result is excess accumulation of glucose in the bloodstream because cells become resistant to the effects of insulin and fail to take up glucose As the type II diabetic condition progresses, many people gain weight and develop more fat cells.2 Treating type II diabetes with insulin-enhancing therapy increases the risk of cardiovascular complications, induces weight gain, and fails to correct the underlying cause of the disease. Many type II diabetics produce too much insulin in a futile attempt to drive glucose into insulin-resistant cells. When doctors prescribe insulin-enhancing drugs to these type II diabetics, a temporarily reduction of serum glucose may occur, but the long-term effects of this excess insu Continue reading >>

How Much Do You Know About Metformin?

How Much Do You Know About Metformin?

Metformin is a drug commonly used in the treatment of Type 2 diabetes. It is sold as a generic and under several brand names, including Glucophage, Glumetza, Riomet, and Fortamet. Both the American Diabetes Association (ADA) and the American Association of Clinical Endocrinologists (AACE) recommend metformin as a cornerstone of therapy for Type 2 diabetes when exercise and dietary changes aren’t enough to keep blood glucose levels in target range. The low cost of the generic forms along with a long history of use make it a good choice for many individuals with Type 2 diabetes. Although metformin has helped many people lower their blood glucose levels, it does have some potential side effects that are worth knowing about. Understanding the risks and benefits of metformin is key to using it successfully. Take this quiz to test your knowledge of this popular diabetes medicine. (You can find the answers later in the article.) Q 1. How does metformin work to lower blood glucose levels? A. It stimulates the pancreas to make more insulin. B. It decreases the amount of glucose produced by the liver and makes it easier for cells to accept glucose from the bloodstream. C. It slows the digestive system’s breakdown of carbohydrates into glucose, allowing more time for insulin to work. D. It suppresses appetite, slows stomach emptying, and inhibits the release of glucagon (a hormone that raises blood glucose levels). 2. In addition to lowering blood glucose, metformin sometimes causes moderate weight loss. TRUE FALSE 3. In research studies, metformin use was associated with which of the following benefits in people with Type 2 diabetes? A. Reduced risk of morning high blood glucose. B. Reduced neuropathy (nerve damage). C. Reduced retinopathy (damage to the retina, a membrane in Continue reading >>

Side Effects Of Metformin 500 Mg Tablets

Side Effects Of Metformin 500 Mg Tablets

Metformin is a prescription medication used primarily in the management of type 2 diabetes. This pill is sold under brand names such as Glucophage and Riomet. A member of the drug group known as biguanides, this drug’s 500 mg tablet is the smallest available pill -- and a common starting dose for this first-line diabetes medication. This widely used medication is an effective tool to help lower blood glucose levels, used alone or in conjunction with other pills or insulin. However, metformin can also produce adverse effects. Video of the Day The most common side effects from metformin use include gastrointestinal (GI) discomfort, including diarrhea, nausea, vomiting, gas and abdominal pain. A diabetes prevention trial, published in the April 2012 issue of “Diabetes Care,” noted that over a 4-year period, 9.8 percent of metformin users reported GI side effects, while only 1.1 percent of those using placebo had these adverse effects. These side effects usually occur at the beginning of metformin therapy and go away as the body becomes adjusted to the medication. Taking the metformin with food and having the dose gradually increased also helps minimize these adverse effects. Extended-release tablets, such as metformin XR (Glucophage XR, Glumetza or Fortamet) may be easier on the stomach -- and an option for anyone who has these common metformin side effects. Other Less Common Side Effects As with most medications, the potential list of side effects is lengthy. Insight into the adverse reactions experienced by metformin users was noted in an analysis of multiple studies published in the February 2012 issue of “Diabetes Care.” While less common than GI discomfort, other potential metformin side effects include dizziness, headache, palpitations, urinary tract infect Continue reading >>

Metformin - Oral, Glucophage

Metformin - Oral, Glucophage

are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis. Your healthcare provider should do blood tests to check how well your kidneys are working before and during your treatment with FARXIGA Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at a higher risk of dehydration if you have low blood pressure; take medicines to lower your blood pressure, including water pills (diuretics); are 65 years of age or older; are on a low salt diet, or have kidney problems Ketoacidosis occurred in people with type 1 and type 2 diabetes during treatment with FARXIGA. Ketoacidosis is a serious condition which may require hospitalization and may lead to death. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL Kidney problems. Sudden kidney injury occurred in people taking FARXIGA. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections (UTI), some that lead to hospitalization, occu Continue reading >>

Metformin Hcl Side Effects By Likelihood And Severity

Metformin Hcl Side Effects By Likelihood And Severity

are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis. Your healthcare provider should do blood tests to check how well your kidneys are working before and during your treatment with FARXIGA Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at a higher risk of dehydration if you have low blood pressure; take medicines to lower your blood pressure, including water pills (diuretics); are 65 years of age or older; are on a low salt diet, or have kidney problems Ketoacidosis occurred in people with type 1 and type 2 diabetes during treatment with FARXIGA. Ketoacidosis is a serious condition which may require hospitalization and may lead to death. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL Kidney problems. Sudden kidney injury occurred in people taking FARXIGA. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections (UTI), some that lead to hospitalization, occu Continue reading >>

Side Effects Of Metformin

Side Effects Of Metformin

I've been recently diagnosed with type 2 and have been taking 2000 mg of Metformin for two weeks. I'm watching my carbs by following a mostly Paleo diet since my diagnosis. Since starting the Metformin, I've been extremely tired, sometimes nauseous and am having some diarrhea. The dr. told me there would be an adjustment period for the meds and I'm calling on Monday. I'm just wondering if anyone else has experienced side effects of Metformin . Moderator T2 insulin resistant Using Basal/Bolus Therapy Just about everyone experiences the gastro-intestinal upset with Metformin. If you are taking the regular type, ask your doctor to change you to the Extended Release (ER). It seems that the "Tummy Trouble" is helped with it. Also; when do you take your Met and do you take it with food? Read your patient information sheet for it. I had some GI problems for about 2-3 weeks but I never had the fatigue or nausea. 115 pounds, Breast Cancer dx'd 6/16, 6 months of chemo and 6 weeks of radiation 2000 metformin ER, 100 mg Januvia,Glimperide, Prolia, Gabapentin, Meloxicam, Probiotic with a Prebiotic, , Lisinopril, B-12, B-6, Tumeric, Magnesium, Calcium, Vit D, and Occuvite mostly vegan diet, low fat and around 125 carbs a day, walk 5-6 miles every other day and 1 hour of yoga and light weights. Just about everyone experiences the gastro-intestinal upset with Metformin. If you are taking the regular type, ask your doctor to change you to the Extended Release (ER). It seems that the "Tummy Trouble" is helped with it. Also; when do you take your Met and do you take it with food? Read your patient information sheet for it. I take it morning and night with food. I started with once a day for a week, then twice a day after that. I knew there would be an adjustment period, I just expected t Continue reading >>

What Are The Possible Side Effects Of Glyburide And Metformin (glucovance)?

What Are The Possible Side Effects Of Glyburide And Metformin (glucovance)?

A A A Medications and Drugs Brand Names: Glucovance Generic Name: glyburide and metformin (Pronunciation: GLYE bure ide and met FOR min) What is the most important information I should know about glyburide and metformin (Glucovance)? What is glyburide and metformin (Glucovance)? Glyburide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels. Glyburide and metformin is used to treat type 2 diabetes. This medication is not for treating type 1 diabetes. Glyburide and metformin may also be used for purposes not listed in this medication guide. This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have a serious side effect such as: pale or yellowed skin, dark colored urine, fever, confusion or weakness; or nausea, upper stomach pain, itching, loss of appetite, clay-colored stools, jaundice (yellowing of the skin or eyes). Less serious side effects may include: sneezing, runny nose, cough or other signs of a cold; headache, mild dizziness; or mild dizziness; or mild nausea or vomiting, diarrhea, upset stomach. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You Continue reading >>

What Are The Possible Side Effects Of Glipizide And Metformin (metaglip)?

What Are The Possible Side Effects Of Glipizide And Metformin (metaglip)?

A A A Medications and Drugs Brand Names: Metaglip Generic Name: glipizide and metformin (Pronunciation: GLIP ih zyd and met FOR min) What is glipizide and metformin (Metaglip)? Glipizide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels. Glipizide and metformin is for people with type 2 diabetes who do not use daily insulin injections. This medication is not for treating type 1 diabetes. Glipizide and metformin may also be used for purposes not listed in this medication guide. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Stop taking this medication and call your doctor at once if you have a serious side effect such as: feeling short of breath, even with mild exertion, swelling or rapid weight gain; pain or burning with urination; nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure). Less serious side effects may include: cold symptoms such as stuffy nose, sneezing, sore throat; headache, dizziness; mild nausea, vomiting, diarrhea, st Continue reading >>

Metformin Hcl

Metformin Hcl

Uses Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. How to use Metformin HCL Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually 1-3 times a day with meals. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects (such as upset stomach), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. If you are already taking another diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping/continuing the old drug and starting metformin. Check your blood sugar regularly a Continue reading >>

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