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What Are The Serious Side Effects Of Metformin?

Metformin Hcl

Metformin Hcl

Uses Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. How to use Metformin HCL Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually 1-3 times a day with meals. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects (such as upset stomach), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. If you are already taking another diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping/continuing the old drug and starting metformin. Check your blood sugar regularly a Continue reading >>

Metformin Side Effects And How To Deal With Them

Metformin Side Effects And How To Deal With Them

Metformin side effects include diabetic neuropathy, brain fog, and digestive issues. You can address them through diet, Vitamin B12, CoQ10, and exercise. Let us understand the drug Metformin in detail and study different forms of metformin, its uses and common metformin side effects along with how to deal with them. Metformin: What Is It Used For? Metformin is an old warhorse in the pharma battle against diabetes. It has been the mainstay in the treatment of Type 2 Diabetes for more than fifty years, often matching or outperforming newer drugs. In fact, many new combination drugs are often created with metformin as one of the main ingredients. Thanks to its long run in the pharmaceutical world, the side effects of Metformin are also well known. The Metformin-PCOS connection has been studied extensively since a majority of health complications associated with PCOS (polycystic ovarian syndrome) are due to hyperinsulinemia (high amounts of insulin in the blood stream). Metformin is known to reduce circulating insulin levels. The use of this drug in women with PCOS has shown highly encouraging results. RELATED: 10 Easy Breakfast Ideas For Diabetics Most Prescribed Names in Metformin Category Include: Fortamet: It is an extended-release formulation that contains metformin hydrochloride. The tablets are designed for once-a-day administration. They deliver either 500 mg or 1000 mg of metformin. The tablet is made using a patented technology called SCOTTM that delivers the active compound slowly and at a constant rate. Glucophage: Glucophage tablets contain metformin hydrochoride. They contain either 500 mg, 850 mg or 1000 mg of the active compound. Glucophage tablets do not contain any special covering and need to be taken multiple times a day until the prescribed dosage is me Continue reading >>

Diabetes Drug Could Be Dangerous: Study

Diabetes Drug Could Be Dangerous: Study

Posted: May 15, 2002 3:35 PM ET | Last Updated: May 15, 2002 A number of patients with diabetes are being given a drug that could kill them, according to researchers in North Carolina. A study on metformin, also sold as Glucophage and Novo-Metformin, says nearly one in four patients could experience dangerous side effects. The study is published in the most current issue of the Journal of the American Medical Association. Metformin helps the body use insulin and is one of the most common drugs used to treat Type II diabetes, sometimes linked to obesity and called "adult-onset" or "non-insulin dependent" diabetes. There are at least 1.2 million Canadians with diabetes according to Health Canada. More than 90 per cent are Type II. Metformin can cause a side-effect called lactic acidosis, a buildup of lactic acid in the blood that is fatal in half of all cases. The label says it shouldn't be used by patients with kidney disease or by those taking heart medication. A study of metformin patients by the University of North Carolina in Chapel Hill found a quarter met that criteria. Fortunately, none of the patients developed lactic acidosis. "It is difficult to determine whether clinicians are aware they are prescribing metformin against a black-box warning," wrote the researchers. "Black-box" refers to the highlighted cautionary information on labels of drugs that have serious side effects. The Canadian Medical Association's guide to prescription drugs lists special precautions for metformin. Metformin is not recommended if you: Common reactions are loss of appetite, nausea and vomiting and a metallic taste in the mouth. Lead researcher Cheryl Horlen says several recent European studies have found similar rates of inappropriate use. Recent studies by Harvard Medical School a Continue reading >>

Metformin Side Effects

Metformin Side Effects

Tweet Metformin does have several common side effects. Like almost all medication, Metformin will affect different people in different ways. The following lists details Metformin side effects, but this does not mean that all people taking Metformin will experience any or all of the following side effects. To make it easier to understand the frequency of the side effects of Metformin, we have divided them by how often they occur. Very common - affecting over 1 in 10 people taking Metformin Disturbance to the gut Nausea Vomiting Diarrhoea Abdominal pain Loss of appetite Common - affecting between 1 in 10 and 1 in 100 people taking Metformin Taste disturbance, usually a metallic taste Very rare - affecting under 1 in 10,000 people taking Metformin Elevated levels of lactic acid in the blood (lactic acidosis) Decreased absorption of vitamin B12 during long-term use Skin reactions such as rash, itching or flushing To find out more about Metformin side effects, people with diabetes should discuss the medication with their doctor and read the information provided by the manufacturer. The list of side effects above does not purport to be a full list of all recognised side effects of Metformin. What should I do if I experience Metformin side effects? All medicines take some getting used to. You should speak to your doctor if any of the side effects become troublesome or painful. If you find your breathing is being affected, along with drowsiness, dizziness and confusion you should stop taking Metformin at once and seek urgent medical attention. These are the symptoms of lactic acidosis, a rare but very serious condition that can be caused by Metformin. Tweet Type 2 diabetes mellitus is a metabolic disorder that results in hyperglycemia (high blood glucose levels) due to the body Continue reading >>

How Much Do You Know About Metformin?

How Much Do You Know About Metformin?

Metformin is a drug commonly used in the treatment of Type 2 diabetes. It is sold as a generic and under several brand names, including Glucophage, Glumetza, Riomet, and Fortamet. Both the American Diabetes Association (ADA) and the American Association of Clinical Endocrinologists (AACE) recommend metformin as a cornerstone of therapy for Type 2 diabetes when exercise and dietary changes aren’t enough to keep blood glucose levels in target range. The low cost of the generic forms along with a long history of use make it a good choice for many individuals with Type 2 diabetes. Although metformin has helped many people lower their blood glucose levels, it does have some potential side effects that are worth knowing about. Understanding the risks and benefits of metformin is key to using it successfully. Take this quiz to test your knowledge of this popular diabetes medicine. (You can find the answers later in the article.) Q 1. How does metformin work to lower blood glucose levels? A. It stimulates the pancreas to make more insulin. B. It decreases the amount of glucose produced by the liver and makes it easier for cells to accept glucose from the bloodstream. C. It slows the digestive system’s breakdown of carbohydrates into glucose, allowing more time for insulin to work. D. It suppresses appetite, slows stomach emptying, and inhibits the release of glucagon (a hormone that raises blood glucose levels). 2. In addition to lowering blood glucose, metformin sometimes causes moderate weight loss. TRUE FALSE 3. In research studies, metformin use was associated with which of the following benefits in people with Type 2 diabetes? A. Reduced risk of morning high blood glucose. B. Reduced neuropathy (nerve damage). C. Reduced retinopathy (damage to the retina, a membrane in Continue reading >>

Metformin

Metformin

Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Tell your doctor if you have kidney disease. Your doctor will probably tell you not to take metformin. Also, tell your doctor if you are over 65 years old and if you have ever had a heart attack; stroke; diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment); a coma; or heart or liver disease. Taking certain other medications with metformin may increase the risk of lactic acidosis. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran). Tell your doctor if you have recently had any of the following conditions, or if you develop them during treatment: serious infection; severe diarrhea, vomiting, or fever; or if you drink much less fluid than usual for any reason. You may have to stop taking metformin until you recover. If you are having surgery, including dental surgery, or any major medical procedure, tell the doctor that you are taking metformin. Also, tell your doctor if you plan to have any x-ray procedure in which dye is injected, especially if you drink or have ever drunk large amounts of alcohol or have or have had liver disease or heart failure. You may need to stop taking metformin before the procedure and wait 48 hours to restart treatment. Your doctor will tell you exactly when you should stop taking metformin and when you should start taking it again. If you experience any of the following symptoms, stop taking metformin and call your doctor immediately: extreme tiredness, weakness, or discomfort; nausea; vomiting; stomach pain; decreased appetite; deep and rapid breathing or shortness of breath; dizzi Continue reading >>

Side Effects Of Metformin 500 Mg Tablets

Side Effects Of Metformin 500 Mg Tablets

Metformin is a prescription medication used primarily in the management of type 2 diabetes. This pill is sold under brand names such as Glucophage and Riomet. A member of the drug group known as biguanides, this drug’s 500 mg tablet is the smallest available pill -- and a common starting dose for this first-line diabetes medication. This widely used medication is an effective tool to help lower blood glucose levels, used alone or in conjunction with other pills or insulin. However, metformin can also produce adverse effects. Video of the Day The most common side effects from metformin use include gastrointestinal (GI) discomfort, including diarrhea, nausea, vomiting, gas and abdominal pain. A diabetes prevention trial, published in the April 2012 issue of “Diabetes Care,” noted that over a 4-year period, 9.8 percent of metformin users reported GI side effects, while only 1.1 percent of those using placebo had these adverse effects. These side effects usually occur at the beginning of metformin therapy and go away as the body becomes adjusted to the medication. Taking the metformin with food and having the dose gradually increased also helps minimize these adverse effects. Extended-release tablets, such as metformin XR (Glucophage XR, Glumetza or Fortamet) may be easier on the stomach -- and an option for anyone who has these common metformin side effects. Other Less Common Side Effects As with most medications, the potential list of side effects is lengthy. Insight into the adverse reactions experienced by metformin users was noted in an analysis of multiple studies published in the February 2012 issue of “Diabetes Care.” While less common than GI discomfort, other potential metformin side effects include dizziness, headache, palpitations, urinary tract infect Continue reading >>

Side Effects Of Metformin Are More Serious Than You Think

Side Effects Of Metformin Are More Serious Than You Think

The Side Effects of Metformin can range from not so serious, to deadly, are the risks of Metformin and Glucophage side effects worth it? This page will give you information that might be able to help you decide that for yourself. Also known as Glucophage, this is an antidiabetic medicine most often used in those with Type 2 Diabetes who are also overweight. It’s also used extensively in women with Polycystic Ovarian Syndrome, a condition known as PCOS, which is often accompanied by higher blood sugar readings which often benefit from the blood sugar lowering effects of Metformin. While at first glance it seems that Side Effects of Metformin are rare, a closer look and a little math show that there are some serious problems that can occur when taking this drug, and others that can and should be prevented easily, but are usually not due to a medical community that simply does not use nutritional supplements in the prevention of even well-known, easily preventable Glucophage side effects. Vitamin B12 Deficiency Vitamin B12 and Folic Acid Deficiency are well-known and well-studied side effects of Metformin. Despite the fact that there have been many studies confirming this problem over and over again in the medical literature, just like the Side Effects of Nitrous Oxide, few doctors warn their patients of this or recommend that they take simple, cheap over the counter Vitamin B12 Supplements in order to avoid this potentially devastating nutritional deficiency. In addition, the long term use of the ‘antacid’ drugs known as H2 receptor antagonist or proton pump inhibitors like Famotidine or Omeprazole, some of the most widely prescribed drugs, can increase this risk, as is mentioned in the Omeprazole Side Effects page. The Vitamin B12 Deficiency Symptoms range anywhere Continue reading >>

Side Effects Of Metformin: What You Should Know

Side Effects Of Metformin: What You Should Know

Metformin is a prescription drug used to treat type 2 diabetes. It belongs to a class of medications called biguanides. People with type 2 diabetes have blood sugar (glucose) levels that rise higher than normal. Metformin doesn’t cure diabetes. Instead, it helps lower your blood sugar levels to a safe range. Metformin needs to be taken long-term. This may make you wonder what side effects it can cause. Metformin can cause mild and serious side effects, which are the same in men and women. Here’s what you need to know about these side effects and when you should call your doctor. Find out: Can metformin be used to treat type 1 diabetes? » Metformin causes some common side effects. These can occur when you first start taking metformin, but usually go away over time. Tell your doctor if any of these symptoms are severe or cause a problem for you. The more common side effects of metformin include: heartburn stomach pain nausea or vomiting bloating gas diarrhea constipation weight loss headache unpleasant metallic taste in mouth Lactic acidosis The most serious side effect metformin can cause is lactic acidosis. In fact, metformin has a boxed warning about this risk. A boxed warning is the most severe warning from the Food and Drug Administration (FDA). Lactic acidosis is a rare but serious problem that can occur due to a buildup of metformin in your body. It’s a medical emergency that must be treated right away in the hospital. See Precautions for factors that raise your risk of lactic acidosis. Call your doctor right away if you have any of the following symptoms of lactic acidosis. If you have trouble breathing, call 911 right away or go to the nearest emergency room. extreme tiredness weakness decreased appetite nausea vomiting trouble breathing dizziness lighthea Continue reading >>

5 Metformin Side Effects That You Should Watch Out For

5 Metformin Side Effects That You Should Watch Out For

ICYMI: Medications are weird and kind of complicated. Sometimes, after a drug is created to treat one problem, we discover it can actually be used to treat other conditions as well#science! Thats the case with metformin, a medication that was initially developed to treat Type 2 diabetes . Over the years, studies (and real-life stories) have shown that taking metformin can lead to weight loss , even in people who arent diabetic. Metformin is an insulin sensitizer, which means it helps the insulin, a hormone made by your pancreas, in your body work better, explains Valentina Rodriguez , M.D., an endocrinologist at NYU Langone Health. Insulin is the hormone that regulates how the body uses and stores glucose and fat, and it's how many of your body's cells convert the glucose in your blood into energy. Steady insulin levels can help to keep blood sugar stable, which prevents hunger and carbs cravings that come with spikes and subsequent drops in blood sugar. Keep in mind, though, that its not a guaranteed weight-loss solution. The weight loss that is seen is really variable, says Rodriguez. Some patients might lose a couple pounds, and some people might actually lose 15 to 20 pounds. As with any drug, there are reactions that can vary from person to personso if you and your doctor decide this is a medication that might help you, here are the side effects you should be aware of. Metformin is most notorious for causing a wide array of stomach issues. It varies from person to person, but up to 40 to 50 percent of people who use classic metformin can develop diarrhea, nausea, vomiting, and/or gassiness, says Rodriguez. Why metformin leads to GI distress is unclear, but because this medication is metabolized by the liver, people who are heavy alcohol drinkers or who already hav Continue reading >>

Metformin Side Effects

Metformin Side Effects

For the Consumer Applies to metformin: oral solution, oral tablet, oral tablet extended release Along with its needed effects, metformin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking metformin: More common Abdominal or stomach discomfort cough or hoarseness decreased appetite diarrhea fast or shallow breathing fever or chills general feeling of discomfort lower back or side pain muscle pain or cramping painful or difficult urination sleepiness Less common Anxiety blurred vision chest discomfort cold sweats coma confusion cool, pale skin depression difficult or labored breathing dizziness fast, irregular, pounding, or racing heartbeat or pulse feeling of warmth headache increased hunger increased sweating nausea nervousness nightmares redness of the face, neck, arms, and occasionally, upper chest seizures shakiness shortness of breath slurred speech tightness in the chest unusual tiredness or weakness Rare Behavior change similar to being drunk difficulty with concentrating drowsiness lack or loss of strength restless sleep unusual sleepiness Some side effects of metformin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common Acid or sour stomach belching bloated excess air or gas in the stomach or intestines full feeling heartburn indiges Continue reading >>

Important Information About The Side Effects Of

Important Information About The Side Effects Of

JANUMET tablets contain 2 prescription medicines: sitagliptin (JANUVIA®) and metformin. Once-daily prescription JANUMET XR tablets contain sitagliptin (the medicine in JANUVIA®) and extended-release metformin. JANUMET or JANUMET XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. JANUMET or JANUMET XR should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while taking JANUMET or JANUMET XR. Metformin, one of the medicines in JANUMET and JANUMET XR, can cause a rare but serious side effect called lactic acidosis (a buildup of lactic acid in the blood), which can cause death. Lactic acidosis is a medical emergency that must be treated in a hospital. Call your doctor right away if you get any of the following symptoms, which could be signs of lactic acidosis: feel cold in your hands or feet; feel dizzy or lightheaded; have a slow or irregular heartbeat; feel very weak or tired; have unusual (not normal) muscle pain; have trouble breathing; feel sleepy or drowsy; have stomach pains, nausea, or vomiting. Most people who have had lactic acidosis with metformin have other things that, combined with the metformin, led to the lactic acidosis. Tell your doctor if you have any of the following, because you have a higher chance of getting lactic acidosis with JANUMET or JANUMET XR if you: have severe kidney problems or your kidneys are affected by certain x-ray tests that use injectable dye; have liver problems; drink alcohol very often, or drink a lot of alcohol in short-term “binge” drinking; get dehydrated (lose large amounts of body fluids, w Continue reading >>

Metformin: Common And Rare Side-effects

Metformin: Common And Rare Side-effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with metformin. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect. Very common (affect more than 1 in 10 people) Disturbances of the gut such as nausea, vomiting, diarrhoea or abdominal pain. The above side effects are most likely to occur when you first start taking metforminand tend to improve over time. They can be prevented or minimised by taking the medicine during or after meals, and by increasing the dose gradually when treatment is started. Follow the instructions given by your doctor. Common (affect between 1 in 10 and 1 in 100 people) Taste disturbance, usually a metallic taste. Very rare (affect fewer than 1 in 10,000 people) Lactic acidosis - a potentially serious condition where there is too much acid in the blood. Symptoms may includebreathing difficultiesand non-specific symptoms such as feeling weak, sick or generally unwell, vomiting, abdominal pain, or unusual muscle pains or discomfort. It's important to consult your doctor straight away if you experience these symptoms. Kidney problems, dehydration, prolonged fasting anddrinkingexcessive amounts of alcohol increase the risk. Decreased absorption of vitamin B12 during long-term use. Skin reactions such as rash, itching or flushing. If you want any more information about the possible side effects ofmetforminyou should talk to your doctor or pharmacist, or read the leaflet that comes with the medicine. If you think you have experienced a side effect, did you know you can report this using the yellow card website ? Continue reading >>

Metformin, Oral Tablet

Metformin, Oral Tablet

Metformin oral tablet is available as both a generic and brand-name drug. Brand names: Glucophage, Glucophage XR, Fortamet, and Glumetza. Metformin is also available as an oral solution but only in the brand-name drug Riomet. Metformin is used to treat high blood sugar levels caused by type 2 diabetes. FDA warning: Lactic acidosis warning This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects. Lactic acidosis is a rare but serious side effect of this drug. In this condition, lactic acid builds up in your blood. This is a medical emergency that requires treatment in the hospital. Lactic acidosis is fatal in about half of people who develop it. You should stop taking this drug and call your doctor right away or go to the emergency room if you have signs of lactic acidosis. Symptoms include tiredness, weakness, unusual muscle pain, trouble breathing, unusual sleepiness, stomach pains, nausea (or vomiting), dizziness (or lightheadedness), and slow or irregular heart rate. Alcohol use warning: You shouldn’t drink alcohol while taking this drug. Alcohol can affect your blood sugar levels unpredictably and increase your risk of lactic acidosis. Kidney problems warning: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug. Liver problems warning: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems. Metformin oral tablet is a prescription drug that’s available as the brand name drugs Glucophage, Glucophage XR, Fortamet, and Glumetza. Glucophage is an immediate-release tablet. All of the other brands are extended-r Continue reading >>

Metformin (oral Route)

Metformin (oral Route)

Description and Brand Names Drug information provided by: Micromedex US Brand Name Fortamet Glucophage Glucophage XR Glumetza Riomet Descriptions Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with a type of oral antidiabetic medicine called a sulfonylurea, or with insulin, will help to lower blood sugar when it is too high and help restore the way you use food to make energy. Many people can control type 2 diabetes with diet and exercise. Following a specially planned diet and exercise will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of metformin you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet or exercise, you will want to test your blood sugar to find out if it is too low. Your doctor will teach you what to do if this happens. Metformin does not help patients does not help patients who have insulin-dependent or type 1 diabetes because they cannot produce insulin from their pancreas gland. Their blood glucose is best controlled by insulin injections. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet Tablet, Extended Release Solution Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ev Continue reading >>

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