What Are The Milligrams For Metformin?

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Metformin Dosage

Metformin Dosage There have been no human studies to identify the optimal dose of metformin that is needed to duplicate the beneficial gene expression effects that are described in the June 2003 issue of Life Extension magazine. For people who want to derive the many proven health benefits of metformin, it might be prudent to follow the dosage schedule used by Type II diabetics. According to the Physician's Desk Reference, the starting dose should be 500 mg of metformin twice a day. (An alternative option is 850 mg of metformin once a day). After one week, increase the dose of metformin to 1000 mg as the first dose of the day and 500 mg as the second dose. After another week, increase to 1000 mg of metformin two times a day. The maximum safe dose described in the Physician's Desk Reference is 2550 mg a day (which should be taken as 850 mg three times a day). According to the Physician's Desk Reference, clinically significant responses in Type II diabetics are not seen at doses below 1500 mg a day of metformin. Anti-aging doctors, on the other hand, have recommended doses as low as 500 mg twice a day to healthy non-diabetics who are seeking to obtain metformin's other proven benefit Continue reading >>

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Popular Questions

  1. kareng236

    Hello all,
    This may seem like a very innocent question .......but is there such a thing as a normal dosage of Metformin? I suppose I am needing to know what the maximum is before insulin is the next option. I was diagnosed as Type 2 at the start of this year and was prescribed 2000mg Metformin daily......building up over a few weeks from 1000mg to 1500mg and now 2000mg. My Doctor does not think that diet alone would do the trick. I realise that we are all different - but I'd like to know if others would consider this a high dosage. Many thanks.

  2. ))Denise((

    Hi Karen
    2000mg is the current maximum dose of metformin (although I'm on 2550mg and have been for 3 years - I'm asking my endocrinologist about this when I see her in March). There are other drugs which can be added to metformin or instead of it including gliclacide, januvia and victoza more info http://www.diabetes.co.uk/diabetes-medication/index.html
    So it isn't usually a straight trip from metformin to insulin.

  3. kareng236

    Hello Denise,
    Thank you so very much for your reply. I have been worried sick about this. I know that further down the line it may be inevitable - but I'd like to ward off that day by really trying to control things with diet, excercise and medication.
    Many many thanks.

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