What Are The Early Symptoms Of Diabetes Insipidus?
The kidney filters about 180 liters of fluid from the blood into the glomerular filtrate and then reabsorbs 178.5 liters back into the blood; excreting 1.5 liters or 1500 mL of urine per day. AntiDiuretic Hormone (ADH), made in the pituitary, is responsible for the reabsorption. Without ADH, the body is unable to concentrate the urine and the person will have up to 20 gallons of pale urine; this causes thirst. The blood becomes concentrated and the urine is dilute. The word “diabetes” is Greek for “hollow tube” because the body becomes like a hollow tube- constantly drinking water and urinating. Those are the major symptoms, accompanied by dehydration and hypotension. The word “insipidus” means “lacking character” because the urine has no color or odor. This has nothing to do with sugar. The word “mellitus” is Greek for “sugar” and diabetes mellitus (DM) aka “sugar diabetes” is a different disease. In DM, the high sugar in the blood (from lack of insulin) pulls water from the tissues (by osmosis) and the kidneys excrete water along with the sugar aka osmotic diuresis. The symptoms are also increased urination and thirst , but the cause is different. Urin Continue reading >>