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Vitamin D And Diabetes Where Do We Stand

Vitamin D Benefits That Can Save Your Life | Reader's Digest

Vitamin D Benefits That Can Save Your Life | Reader's Digest

23 Vitamin D Benefits That Can Save Your Life Vitamin D is kind of a big dealare you getting all the vitamin D you really need? Vitamin D is called the sunshine vitamin because our bodies produce it in response to sunlight. Given valid concerns about skin cancer and premature aging, we tend to slather on sunscreenwhich protects skin, but also limits our bodies ability to produce vitamin D. Most doctors recommend spending about 15 minutes a day in the sun without sunscreen to give your body a chance to create its daily dose of vitamin D, Michael Holick, MD , professor, and director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center says. You can also get it from milk and other types of dairy, and some breakfast cereals which are fortified with vitamin D. Healthier pregnancies for moms and babies Expecting moms with low blood levels of vitamin D during pregnancy are at higher risk for potentially fatal high blood pressure (preeclampsia), early delivery, and low birth weight babies. And it doesnt stop theremoms who are deficient in D are also more likely to require a C-section delivery and are at greater risk for infections, says Dr. Holick. Vitamin D is crucial for moms because D receptors in the uterine muscle may strengthen contractions during labor; the vitamin may also boost immunity for mom and baby, he says. So how much vitamin D does a pregnant woman need? In one study , women who took high doses of vitamin D during pregnancy had a much lower risk of complications. Discuss with your doctor whether you could benefit from supplements. Another reason for expecting moms to get enough D: Researchers out of the Keck School of Medicine at the University of Southern California report that pregnant women who are deficient may actually p Continue reading >>

Vitamin D And Diabetes: Where Do We Stand?

Vitamin D And Diabetes: Where Do We Stand?

Vitamin D and diabetes: Where do we stand? Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KU Leuven, Leuven 3000, Belgium. Electronic address: [email protected] Diabetes Res Clin Pract. 2015 May;108(2):201-9. doi: 10.1016/j.diabres.2015.01.036. Epub 2015 Feb 7. The potential beneficial effects of supplementing vitamin D or treatment with pharmacological doses of vitamin D in the prevention or cure of diseases like type 1 (T1D) or type 2 diabetes (T2D) remains the subject of debate. Data from epidemiological and association studies clearly indicate a correlation between vitamin D deficiency and a higher prevalence of both forms of diabetes. In animal models, vitamin D deficiency predisposes to type 1 and type 2 diabetes, whereas high doses of vitamin D or its active hormonal form, 1,25-dihydroxyvitamin D, prevent disease. Large scale, randomized, blinded prospective studies however, remain lacking. Here we discuss the current literature on a role for vitamin D in diabetes. We propose, in particular, to avoid vitamin D deficiency in individuals at risk of developing T1D or T2D. Applying international guidelines on supplementation of vitamin D using small daily doses of vitamin D (500-1000IU) may contribute to reduce the burden of diabetes by preventing vitamin D deficiency. Any other recommendations are at present not supported by data. Continue reading >>

Vitamin D Can Save You From Diabetes And Dementia

Vitamin D Can Save You From Diabetes And Dementia

By Dr. Mercola Do you know your vitamin D level? If not, a simple blood test called 25(OH)D, or 25-hydroxyvitamin D, can reveal your levels and give you incredible insight into your potential future risk of disease. Low vitamin D levels are widely known to harm your bones, leading them to become thin, brittle, soft, or misshapen. But a lack of vitamin D does not only impact your bones. Far from it. You see, vitamin D isn’t a vitamin at all. It’s a steroid hormone that influences virtually every cell in your body. From your heart to your brain to your immune system, maintaining optimal vitamin D levels is incredibly important. It’s also incredibly easy, because the best way to get vitamin D is to have regular exposure to the sun or a high-quality tanning bed. If those aren’t options, you can take vitamin D3 orally (along with some synergistic nutrients, which I’ll discuss below). It’s one of the least expensive vitamin supplements… The point is, there’s no reason to put your health at risk from low vitamin D levels… yet researchers such Dr. Michael Holick estimate that 50 percent of the general population is at risk of vitamin D deficiency and insufficiency. If you’re among them, new research shows your risk of diabetes and other metabolic disorders may be significantly increased. Vitamin D Deficiency Linked to Diabetes You’re probably aware that obesity is associated with type 2 diabetes, but a new study found low vitamin D levels may be an even more significant factor. In a study of more than 100 people, those with low vitamin D levels were more likely to have type 2 diabetes, pre-diabetes, or metabolic syndrome, regardless of their weight. Among obese people, those without metabolic disorders had higher levels of vitamin D than those with such di Continue reading >>

Diabetes Type 2: Vitamin D Deficiency Could Increase Risk Of Condition | Health | Life & Style | Express.co.uk

Diabetes Type 2: Vitamin D Deficiency Could Increase Risk Of Condition | Health | Life & Style | Express.co.uk

Diabetes symptoms: Type 2 risk lowered by taking vitamin D supplementsq Diabetes type 2: Vitamin D deficiency could increase risk of condition Diabetes is a chronic disease that affects millions of people worldwide. Uncontrolled cases can cause blindness, kidney failure, heart disease and other serious conditions, said Spritzler. Most health organisations recommend maintaining a vitamin D blood level of at least 30 ng/ml. However, for many people, supplementing with 2,0004,000 IU of vitamin D daily may be necessary to achieve and maintain optimal levels. Good food sources of vitamin D include fatty fish and cod liver oil. In addition, sun exposure can increase vitamin D levels in the blood. Diabetes symptoms: Vitamin D helps to control blood-sugar levels Diabetes is a common life-long health condition. There are 3.5 million people diagnosed with diabetes in the UK and an estimated 500,000 who are living undiagnosed with the condition. People should be aware signs and symptoms of diabetes are not always obvious and the condition is often diagnosed during GP check ups. Diabetes symptoms: Between 2,000 and 4,000 UI of vitamin D is optimum, nutritionist claims Some herbs may help to increase insulin sensitivity, and reduce the chances of diabetes progression, Spritzler added. Curcumin has strong anti-inflammatory properties, and could lower the risk of arthritis and diabetes. Berberine could help to lower blood-sugar, and may be as effective as metformin - a widely used medication for diabetes - said the nutritionist. Eating a high-fibre diet, cutting down on portion sizes and drinking water as your primary beverage could also lower your risk of diabetes , said Spritzler. Diabetes symptoms: Fatigue and feeling thirsty are signs of condition Diabetes symptoms: Fatty fish an Continue reading >>

Vitamin D: 5 Conditions It Can Help

Vitamin D: 5 Conditions It Can Help

Multivitamins, meanwhile arent even recommended by the U.S. Preventive Services Task Force . The most commonly known positive health outcome associated with good vitamin D levels is bone health. The ones that are very evidenced are going to be bone issues, says Sontag. As far as bone thinning osteoporosis, osteopenia, as well as rickets in kids and osteomalacia in adults those are the ones that are really associated with legitimate vitamin D deficiency, in which case vitamin D helps. Newer evidence shows that it also helps prevent falls and fractures in the elderly, and thats why the elderly are now supposed to be taking higher doses of vitamin D. Vitamin D has long been known for its association with good bone health. But new research suggests the sunshine vitamin could be effective at warding off a host of other ailments as well. A study published last month in PLOS One found that people with vitamin D deficiency could face a higher risk of developing type 2 diabetes. Researchers studied healthy, older adults with no prior warning signs of diabetes or prediabetes. Over a 12-year period, many participants developed diabetes or prediabetes. Of those participants, it was found that vitamin D deficiency was a strong predictor of whether a participant would develop those complications. Ultimately, it was found that those with vitamin D levels above 30 nanograms per millilitre had one-third the risk of developing diabetes, while those with levels above 50 nanograms per millilitre had one-fifth the risk. The studys authors acknowledged that more research is needed, but that the results show promise. Further research is needed on whether high 25-hydroxyvitamin D levels might prevent type 2 diabetes or the transition from prediabetes to diabetes, said study co-author Cedric F Continue reading >>

The Many Health Benefits Of Vitamin D, The Sunshine Vitamin

The Many Health Benefits Of Vitamin D, The Sunshine Vitamin

The many health benefits of Vitamin D, the sunshine vitamin Originally published April 16, 2018 at 12:27 pm A few food sources of vitamin D (sardines, egg yolks, fortified milk and yogurt, and mushrooms) sitting in the best natural source of all sunshine. (Carrie Dennett / Special to The Seattle Times) An estimated 4 in 10 Americans are deficient in vitamin D, but it's simple to test for, and simple to treat. Were fortunate in the United States that we see relatively few cases of severe vitamin D deficiency rickets which causes delayed growth and visible skeletal deformities in children. However, that doesnt mean that vitamin D deficiency is rare. In fact, an estimated 4 in 10 Americans are deficient. Thats concerning, because the potential health consequences of vitamin D deficiency are serious. Not only is a lack of vitamin D linked to osteoporosis, heart disease, diabetes, autoimmune diseases, high blood pressure, polycystic ovary syndrome and poor pregnancy outcomes, but it may increase the risk of developing metabolic syndrome. Metabolic syndrome is a cluster of conditions high blood pressure, high blood sugar, excess body fat around the waist and abnormal levels of cholesterol or triglycerides that happen together, increasing the risk of heart disease, stroke and diabetes. New research has found that postmenopausal women who are deficient in vitamin D are more likely to have metabolic syndrome, and previous research has found similar associations in both men and women. The fact that so many Americans may be D-ficient isnt too surprising when you consider that modern life often means workdays spent at a desk and leisure time binge-watching the latest Netflix series or playing Words With Friends. Thats a lot of indoor time, but even when we are outdoors, were often Continue reading >>

Vitamin D And Diabetes: What You Need To Know

Vitamin D And Diabetes: What You Need To Know

Vitamin D and Diabetes: What You Need To Know Thought LeadersDr. Cedric GarlandDepartment of Family Medicine and Public HealthUniversity of California San Diego An interview with Dr. Cedric Garland, DrPH, conducted by Kate Anderton, BSc Why is vitamin D important for the human body? Vitamin D is essential to the human body for a number of reasons. The first is that vitamin D is needed to absorb calcium, and also move calcium from the blood into the bone. This is necessary to prevent rickets. Image Credit: Syda Productions / Shutterstock Vitamin D is produced only in response to exposure to sunlight. Inadequate sunlight was discovered to be the main cause of rickets in 1832 in Poland. This was before the vitamin D compound was discovered. In 1890, Theodore Palm published a paper showing that rickets was due to a deficiency of sunlight. Sunlight was later found to be the source of Vitamin D, solving the mystery of the high incidence of rickets in the dark, narrow streets of winter in Europes major cities, especially those with air pollution such as London and Warsaw. A few decades later, vitamin D was discovered by Elmer McCollum of The Johns Hopkins University in Baltimore. Vitamin D is also important for the prevention and alleviation of chronic diseases in addition to rickets. The first example of this was the discovery that Vitamin D prevents cancer by our group in 1980. Since then, there have been 8,550 papers published on vitamin D and cancer. Much of this progress was also due to William B, Grant, Ph.D., of the Sunlight and Nutrition Research Center in California). We are now confident that vitamin D can prevent certain forms of cancer. Similar epidemiological research has implicated vitamin D deficiency in multiple sclerosis. The most recent discovery in the hist Continue reading >>

Vitamin D Research

Vitamin D Research

Vitamin D supplement science abstracts related to diabetes and pre-diabetes metabolic syndrome. Go to PubMed and copy the title in the search field. New insights about vitamin d and cardiovascular disease: a narrative review. Hypovitaminosis D Associations with Adverse Metabolic Parameters Are Accentuated in Patients with Diabetes Mellitus Type 2: A BMI-Independent Role of Adiponectin? Study on the relationship between serum 25-hydroxyvitamin D levels and vascular calcification in hemodialysis patients with consideration of seasonal variation in vitamin D levels. Vitamin D, diabetic neuropathy and supplementation post-gestational diabetes. Plasma vitamin D levels and risk of metabolic syndrome in Canadians. Health effects related to low vitamin d concentrations: beyond bone metabolism. Relationship between vitamin D and hyperglycemia in older people from a nationally representative population survey. Vitamin D deficiency and endothelial dysfunction in non-dialysis chronic kidney disease patients. Vitamin D Deficiency and Supplementation and Relation to Cardiovascular Healt The effect of vitamin D supplementation on peripheral regulatory T cells and cell function in healthy humans: a randomized controlled trial. Vitamin d and metabolic syndrome risk factors: evidence and mechanisms. Does Vitamin D deficiency play a role in peripheral neuropathy in Type 2 diabetes? Effect of daily vitamin D supplementation on hemoglobin A1c in patients with uncontrolled type 2 diabetes mellitus: a pilot study. Vitamin D3 supplementation improves insulin sensitivity in subjects with impaired fasting glucose. Vitamin D supplementation to prevent the progression of prediabetes to diabetes: getting closer to a recommendation. Vitamin D supplementation for cardiovascular disease prevention. T Continue reading >>

Vitamin D And Diabetes: Where Do We Stand?

Vitamin D And Diabetes: Where Do We Stand?

Vitamin D and diabetes: Where do we stand? The potential beneficial effects of supplementing vitamin D or treatment with pharmacological doses of vitamin D in the prevention or cure of diseases like type 1 (T1D) or type 2 diabetes (T2D) remains the subject of debate. Data from epidemiological and association studies clearly indicate a correlation between vitamin D deficiency and a higher prevalence of both forms of diabetes. In animal models, vitamin D deficiency predisposes to type 1 and type 2 diabetes, whereas high doses of vitamin D or its active hormonal form, 1,25-dihydroxyvitamin D, prevent disease. Large scale, randomized, blinded prospective studies however, remain lacking. Here we discuss the current literature on a role for vitamin D in diabetes. We propose, in particular, to avoid vitamin D deficiency in individuals at risk of developing T1D or T2D. Applying international guidelines on supplementation of vitamin D using small daily doses of vitamin D (500-1000IU) may contribute to reduce the burden of diabetes by preventing vitamin D deficiency. Any other recommendations are at present not supported by data. Continue reading >>

Vitamin D And Diabetes: Where Do We Stand? - Sciencedirect

Vitamin D And Diabetes: Where Do We Stand? - Sciencedirect

Volume 108, Issue 2 , May 2015, Pages 201-209 Vitamin D and diabetes: Where do we stand? Author links open overlay panel ChantalMathieu Get rights and content The potential beneficial effects of supplementing vitamin D or treatment with pharmacological doses of vitamin D in the prevention or cure of diseases like type 1 (T1D) or type 2 diabetes (T2D) remains the subject of debate. Data from epidemiological and association studies clearly indicate a correlation between vitamin D deficiency and a higher prevalence of both forms of diabetes. In animal models, vitamin D deficiency predisposes to type 1 and type 2 diabetes, whereas high doses of vitamin D or its active hormonal form, 1,25-dihydroxyvitamin D, prevent disease. Large scale, randomized, blinded prospective studies however, remain lacking. Here we discuss the current literature on a role for vitamin D in diabetes. We propose, in particular, to avoid vitamin D deficiency in individuals at risk of developing T1D or T2D. Applying international guidelines on supplementation of vitamin D using small daily doses of vitamin D (5001000IU) may contribute to reduce the burden of diabetes by preventing vitamin D deficiency. Any other recommendations are at present not supported by data. Continue reading >>

Low Vitamin D May Raise The Risk Of Diabetes 5 Times That Of Individuals With A Healthy Blood Level Of This Vitamin.

Low Vitamin D May Raise The Risk Of Diabetes 5 Times That Of Individuals With A Healthy Blood Level Of This Vitamin.

"There was a strong relationship between vitamin D being low and a higher incidence of diabetes," says study co-author, Cedric Garland, DrPH, an adjunct professor of family medicine and public health at the University of California San Diego School of Medicine. Foods high in vitamin D include salmon, tuna, eggs, and fortified dairy products. The participants who were followed by Garland and his team were part of the ongoing Rancho Bernardo Study , a National Institutes of Health population-based trial of older adults, which included patients who were middle-income Caucasians living in a southern California suburb; the average age was 74 years on average at the start of the vitamin D portion of the study.5 These participants were confirmed as healthy, having no signs or symptoms of pre-diabetes or diabetes, initially.5During the study, the researchers measured blood levels of vitamin D from over the first two years and gave the men and women a fasting blood glucose test every two years. If the fasting blood glucose test was high (100 milligrams/deciliter or above), an oral glucose tolerance test was done to confirm the likelihood of diabetes. By the end of the follow-up portion of the study, 47 people were diagnosed as having developed diabetes and 337 had been identified with prediabetes. Based on these results, Garland and his team confirmed that the higher the vitamin D in the blood, the less likely they were to get diabetes.5 A Closer Look at the Relationship Between Diabetes and Vitamin D In trying to understand the study findings, it is important to appreciate that experts disagree on what a normal blood level for vitamin D should be,6but for the purposes of this study, the researchers identified a minimum healthy level of serum 25-hydroxyvitamin D to be 30 nanogr Continue reading >>

Vitamin D And Type 2 Diabetes Mellitus: Where Do We Stand? - Em|consulte

Vitamin D And Type 2 Diabetes Mellitus: Where Do We Stand? - Em|consulte

Received:3January2011; accepted:8January2011 Vitamin D and type 2 diabetes mellitus: Where do we stand? Vitamine D et diabte de type 2: le point en 2011 , P.Delanaye b , J.-C.Souberbielle c , R.-P.Radermecker d aDepartment of Clinical Chemistry, University of Liege, CHU Sart-Tilman, 4000 Lige, Belgium bDepartment of Nephrology, Dialysis and Hypertension, University of Liege, CHU Sart-Tilman, 4000 Lige, Belgium cLaboratoire dexplorations fonctionnelles, hpital NeckerEnfants-Malades, 75743 Paris, France dDepartment of Diabetes, Nutrition and Metabolic Disorders, University of Liege, CHU Sart-Tilman, 4000 Lige, Belgium Corresponding author. Tel.: +32 43 66 76 92; fax: +32 43 66 76 91. In-vitro and observational studies have established a link between vitamin D deficiency and different type 2 diabetes outcomes (insulin resistance, insulin secretion, glucose intolerance). Although the number of randomized controlled trials vs placebo is small, vitamin D (VTD) has been shown to prevent increases in glucose concentration and insulin resistance, enhance insulin sensitivity and reduce systolic blood pressure in type 2 diabetic patients. In this review, we have focused on the potential mechanisms that might explain the association between VTD and type 2 diabetes mellitus (T2DM). We have also evaluated the different epidemiological and observational studies on the topic, as well as the various interventional studies. Although the in vitro studies appear to be promising in explaining the link between VTD metabolism and T2DM, the results of in vivo studies are conflicting. This could be related to differences in their methodological approaches. Although more studies are needed to confirm the role of VTD in the treatment of T2DM, there is nevertheless enough evidence at this time to Continue reading >>

Vitamin D And Diabetes: Where Do We Stand?

Vitamin D And Diabetes: Where Do We Stand?

... Vitamin D deficiency and abnormal glucose metabolism have been shown to be associated in humans and causally related in animal models 2], although the efficacy of vitamin D repletion/supplementation as a diabetes treatment is not yet universally accepted. We have previously reported that diverse interventions that reduce insulin resistance and hyperinsulinemia ameliorate non-classic adrenal hyperplasia (NCAH), biochemically and phenotypically, much as such interventions ameliorate polycystic ovarian syndrome (PCOS) [3,4]. ... ... We have also reported that NCAH is very frequently present in patients with Type 2 diabetes mellitus (T2DM), the quintessential disorder of insulin resistance, in our community who are not taking insulin sensitizers and have not developed T2DM in the setting of chronic Hepatitis C without a family history of T2DM [3,5]. Vitamin D repletion in patients who are vitamin D-deficient/insufficient mitigates insulin-resistance- associated disorders such as T2DM, PCOS, and NCAH 2,4]; however, the present report is the first report of the amelioration of elevated serum 17-OHP during vitamin D repletion in a patient with likely NCAH. ... ... Serum 25-OH-vitamin D levels have been reported to be lower than in the general population in many conditions associated with insulin resistance, including: obesity, T2DM, PCOS, and both classic and non-classic congenital adrenal hyperplasia [2][3][4]. Vitamin D receptors are abundant in the adrenal cortex [6], suggesting a possible direct regulatory role for vitamin D in the biosynthesis of adrenal steroids. In addition, vitamin D repletion/supplementation has been reported to improve insulin sensitivity and conditions associated with insulin resistance such as T2DM, PCOS, and both classic and non-classic 11-hy Continue reading >>

Low Vitamin D Levels And Diabetic Eye Disease In Kids And Teens

Low Vitamin D Levels And Diabetic Eye Disease In Kids And Teens

Low Vitamin D Levels and Diabetic Eye Disease in Kids and Teens Vitamin D deficiency is associated with retinopathy in children and adolescents with type 1 diabetes, by Harleen Kaur and colleagues. Diabetes Care 34:14001402, 2011 What is the problem and what is known about it so far? People with diabetes may have problems with the small blood vessels found in the eyes and nerves. Diabetes can cause blood vessels to become weak, and they can bleed or leak. Diseases in the eyes, in nerves of the feet and hands, and in the kidneys are the most common form of this problem. When the damage is in the eyes, it can cause vision problems and even blindness. Eye disease can affect anyone with type 1 or type 2 diabetes. Low levels of vitamin D have been linked to blood vessel damage from diabetes, but only in mice and adults. No such studies have been done in youths with type 1 diabetes. Why did the researchers do this particular study? The researchers wanted to know if low levels of vitamin D are connected to problems of the small blood vessels in young people with type 1 diabetes. The researchers studied 517 kids, teens, and young adults ages 8 to 20 years. The researchers measured participants vitamin D levels. Then they tested for small blood vessel damage in the eyes, feet, and kidneys. Participants with low levels of vitamin D had more problems with the blood vessels of the eyes. The feet and kidneys were not affected. The children were studied only one time. Because of this, researchers cannot be sure that the damage was caused by the low levels of vitamin D. Low vitamin D levels seem to be connected to problems with the blood vessels in the eyes in kids and teens with type 1 diabetes. More studies are needed to find out if low vitamin D levels are the cause of the damage Continue reading >>

Vitamin D Deficiency: A New Risk Factor For Type 2 Diabetes

Vitamin D Deficiency: A New Risk Factor For Type 2 Diabetes

Vitamin D Deficiency: A New Risk Factor for Type 2 Diabetes Mezza T. Muscogiuri G. Sorice G.P. Prioletta A. Salomone E. Pontecorvi A. Giaccari A. Endocrinologia e Malattie del Metabolismo Universit Cattolica del Sacro Cuore Policlinico A. Gemelli Largo A. Gemelli 8, IT00168 Rome (Italy) Recent compelling evidence suggests a role of vitamin D deficiency in the pathogenesis of insulin resistance and insulin secretion derangements, with a consequent possible interference with type 2 diabetes mellitus. The mechanism of this link is incompletely understood. In fact, vitamin D deficiency is usually detected in obesity in which insulin resistance is also a common finding. The coexistence of insulin resistance and vitamin D deficiency has generated several hypotheses. Some cross-sectional and prospective studies have suggested that vitamin D deficiency may play a role in worsening insulin resistance; others have identified obesity as a risk factor predisposing individuals to exhibit both vitamin D deficiency and insulin resistance. The available data from intervention studies are largely confounded, and inadequate considerations of seasonal effects on 25(OH)D concentrations are also a common design flaw in many studies. On the contrary, there is strong evidence that obesity might cause both vitamin D deficiency and insulin resistance, leaving open the possibility that vitamin D and diabetes are not related at all. Although it might seem premature to draw firm conclusions on the role of vitamin D supplementation in reducing insulin resistance and preventing type 2 diabetes, this manuscript will review the circumstances leading to vitamin D deficiency and how such a deficiency can eventually independently affect insulin sensitivity. The increasing prevalence of obesity [ 1 ] is Continue reading >>

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