Switching From Apidra To Novolog

Apidra V. Novolog V. Humalog And Sodium Retention - Diabetes

Apidra v. Novolog v. Humalog and sodium retention So, I know this has come up before, but I wanted to see what you guys thought about the differences. I use Novolog in my pump and in a pen before that. I've noticed that it takes about 2 hours after administration for it to really start dropping my levels, and it is kinda making it difficult for bg corrections. It works alright with meals, but I usually have to take it about 30 minutes before if I want to stay under 180-200 mg/dL one hour post-meal. I've read that Apidra peaks a lot faster and harder, and I'm thinking that that might be better for me, as the Novolog is taking a little too long for my liking. My endo was pretty apathetic toward changing from one to the other, but I think I'm going to give Apidra a try. I guess the same goes for Humalog, but I've read that it has an even slower peak than Novolog. Also, does Apidra help with sodium retention? I've heard of weight loss/gain when switching insulins, but I don't know which rapid-acting insulin is the most notorious offender in that category. Continue reading >>

Compare Apidra Vs Novolog - Iodine.com

Head-to-head comparisons of medication uses, side effects, ratings, and more. Apidra (insulin glulisine) is an insulin that controls blood sugar during your meals, but you'll still have to follow your doctor's diet and exercise plan. Novolog (insulin aspart) is a fast-acting insulin that provides meal-time blood sugar control. For long-term control, you'll need to take Novolog (insulin aspart) with other medicines to keep your overall blood sugar down. 3.5/ 5 average rating with 177 reviewsforNovolog Apidra (insulin glulisine) starts working in as soon as 15 minutes. Programs are available to lower your copay. Talk to your doctor or pharmacist. Can be used in people over 65 and children 4 years of age and older. When used correctly, this medication will l lower blood sugar every time you use it and prevent the harmful, long-term effects of high sugar levels on your organs and blood vessels. You can easily change the dose of Novolog (insulin aspart) to fit your individual needs. Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression. Can use Novolog (insulin aspart) even if you have liver or kidney problems, unlike many other blood sugar-lowering medicines. Your doctor might have to check your kidneys and liver regularly if you've had kidney or liver problems in the past. Since Apidra (insulin glulisine) is an injectable, it might not be a good treatment option for people who are afraid of needles. Only available as a brand name, so Apidra (insulin glulisine) can be expensive. Might have to check your blood sugar multiple times a day, usually before each meal. Novolog (insulin aspart) is likely to cause moderate weight gain. Higher risk of low blood sugar episodes compared to other ki Continue reading >>

Diets and Diabetes – Let’s Compare!

Rapid-acting Analogues

Rapid-Acting Analogues Short-Acting Insulins Intermediate-Acting Insulins Long-Acting Insulins Combination Insulins Onset: 12 - 18 min Peak: 1-3 hours Duration: 3-5 hours Solution: Clear Comments: NovoLog should generally be given immediately before a meal (start of meal within 5-10 minutes after injection) because of its fast onset of action. NovoLog is homologous with regular human insulin with the exception of a single substitution of the amino acid proline by aspartic acid in position B28 (beta chain). Insulin lispro (Humalog) and insulin aspart (Novolog), when administered intravenously, show pharmacodynamic parameters similar to regular insulin. Mixing NPH: If NovoLog is mixed with NPH human insulin, NovoLog should be drawn into the syringe first. The injection should be made immediately after mixing. Regular insulin: Compatible - but NO support clinically for such a mixture. Draw up Novolog first before drawing up Regular Insulin. Mixtures should not be administered intravenously. When used in external subcutaneous infusion pumps for insulin, NovoLog should not be mixed with any other insulins or diluent. When rapid-acting insulin is mixed with either an intermediate- or long-acting insulin, the mixture should be injected within 15 min before a meal. INDICATIONS AND USAGE Treatment of Diabetes Mellitus NovoLog is an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. DOSAGE AND ADMINISTRATION Dosing NovoLog is an insulin analog with an earlier onset of action than regular human insulin. The dosage of NovoLog must be individualized. NovoLog given by subcutaneous injection should generally be used in regimens with an intermediate or long-acting insulin [see package insert for Warnings and Precautions (5), How Supplied Continue reading >>

Switching From Novolog To Humalog

Looks like Ill be switching insulins, due to new Rx coverage, effective in January 2018. My endo has said they are essentially the same, but I thought Id check in here. Also on Lantus, but that will stay the same. Doing MDI with a CGM right now. I think there are minor differences that can be noticeable for some people. I tried Humalog briefly and found that I needed much more of it for carbs and corrections, that I had to increase my basal rates (I was using it in a pump) and that it didnt last as long. My son has not used Humalog, but Ive heard the same as @Scott_Eric . Calebs endo discourages its use bc of experience hes seen with pumping - it being more susceptible to clogging. Any chance your insurance is Aetna? We got a similar notice. I made that switch and didnt notice much of a differenceI think humalog may be a tiny bit faster/have less of a tail, but hard to say. Im also on MDI (humalog and tresiba, formerly lantus), so the clogging/pumping concern wasnt an issue. I used NovoLog for years and Ive used Humalog for years. I dont see any functional difference between the two. I have noticed on the internet some people claim they find difference between the two. If thats true its now a your mileage may vary issue Ive used both. I need about 12% more insulin on Humalog than on Novolog on MDI. But in a previous thread on a different message board, I noted that there were others who had the opposite experience. Also Humalog gets started a little faster than Novolog for me and at least in previous years had a slightly shorter tail. However, this year Ive noticed that a typical mealtime dose (8 units) of Humalog takes between five and six hours to finish working, which is as long as Novolog took the last time I was on it about three years ago.It may be just that at m Continue reading >>

Humalog And Novolog - Medhelp

Common Questions and Answers about Humalog and novolog Is there a difference between Humalog and Novolog insulins? I was told there are exactly the same. But is this true? I've never used Novolog , but had used Humalog for quite awhile until about 6 months ago. The Humalog worked pretty well for me,but when i switched to a pump, my doctor had me try Apidra and it's really worked great. My blood sugar comes down a lot faster with the Apidra and it keeps my post meal readings pretty good too.... I have a very physical job for four hours a day and I don't even need my Humalog when I eat lunch. My pen generally lasts me the whole month. My Humalog is only good for 28 - 30 days. As far as I know, once your insulin pen is opened, that's how long most of them last no matter how much insulin you use. I have been using Novolog Pens for about a year now, and recently have had several problems with their quality. My pharmacist is telling me that most diabetics use Humalog ( and Novolog use is rare). Has anyone else had problems or switched from Novolog to Humalog? Are there Novolog users out there?Thanks.... I really feel like it has something to do with Novolog and have read that it can be a side effect and even a sign of an allergic reaction to Novolog . Has ANYONE else had this problem? Does anyone have any advice? Please help if you can.....The doctor said to give her Benadryl to help and I do at night but not during the day. It doesn't seem fair to drug her all the time and make her sleepy. For example I don't know why, but she said that Lantus works better if you give the shots on your tummy and buttox and novolog / humalog (fast acting) works better if given in your legs... anyway, this is a lot of information and if you can, please have him see a Diabetes Educator... al l Continue reading >>

Switching From Apidra To Novolog...

This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies. Learn More. So on Monday I am switching from Apidra to Novolog by doctors choice. No idea why exactly but will anything have to change? Like will my I:C ratios change or anything at all? I am only 5 months into this and am just finally getting things down!!! Thanks Not a teen, but yes, things will probably change. My son recently changed back from Apidra to Novolog by our choice. He was having problems with feeling low all the time. these are the kind of questions that you should feel able to ask your doctor. if s/he's going to change things and you have questions then you should be able to ask her/him and get the answers you need. if you don't feel comfortable or your doctor won't answer your questions or take you serously then you might want to look for a new doctor. maybe have your mom or dad call and ask of you're not going back in before the switch? i do know that different insulins have varying release times. i'm on novolog and i have to wait until 3 hours after my last insulin bolus to give myself more insulin to make my bg go down if it's high, but i think there's other insulins that you only have to wait 2 hours for. there's going to be changes, but i can't really tell you any more than that. hope the switch goes well! Continue reading >>

Effect Of Apidra Compared To Humalog In Decreasing Post-prandial Hyperglycemia

This study aims to compare the post-meal blood glucose values of two drugs in a "real-world‟ setting. This is a randomized, open-label trial that aims to compare the glycemic excursion following food intake following post-meal injection of Glulisine (Apidra) insulin and Lispro (Humalog) insulin in a real-world setting. Children participating in the Florida Camp for Children and Youth with Diabetes will be randomized to receive either Glulisine or Apidra to cover carbohydrates after meals. The difference in blood glucose values will be analyzed before and 2 hours after meals to see if there is a difference in post-prandial hyperglycemia between groups. Study Type : Interventional (Clinical Trial) Actual Enrollment : 107 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Supportive Care Official Title: Comparison of Effectiveness of Glulisine and Lispro in Decreasing Post-Prandial Hyperglycemia in a Real-World Setting Study Start Date : June 2011 Primary Completion Date : August 2012 Study Completion Date : August 2012 Resource links provided by the National Library of Medicine U.S. FDA Resources Arm Intervention/treatment Active Comparator: Humalog Subjects on this treatment arm will receive Humalog insulin for their bolus doses, with doses optimized individually to achieve glycemic targets at daily medical rounds with their cabin physicians. Drug: Humalog Subjects on this treatment arm will receive Humalog insulin for their bolus doses, with doses optimized individually to achieve glycemic targets at daily medical rounds with their cabin physicians. Other Name: Insulin lispro Active Comparator: Apidra Subjects on this treatment arm will receive Apidra insulin for their bolus doses, with doses optimiz Continue reading >>

The Switch: How I Accidentally Found The Right Insulin

WRITTEN BY: Chris Wiggins Note: This article is a part of our library of resources in Tools & How to. Check out more helpful product reviews and run downs on different diabetes management devices here. One of the unfortunate realities of being a Type 1 diabetic in the American healthcare system is that we don’t always have control of the medications we receive. I’ve changed insulin back and forth from Novolog to Humalog over my time with the pump due merely to the preference of my insurance company at the time. While those two insulins were nearly identical based on my blood sugar levels, I recently was put on a new insulin for the reason that it is the only insulin my new insurance covered. That insulin is Apidra, an insulin I had never even heard mentioned by my doctors despite it being on the market since 2004. At first I didn’t know much about the new insulin, except that it was similar to Humalog, the insulin I had previously been prescribed. I was told it was slightly faster acting, but my dosages for carbohydrates and lowering my blood sugar shouldn’t change by much. While fairly skeptical about the new insulin I chose my first few meals carefully (low carbs, high fiber) and monitored my blood sugar closely. Everything seemed fine and similar to Humalog, so I figured it was just the same medicine with a new name/logo. Then after a few days I tested the insulin against a high carbohydrate sandwich from one of my favorite sandwich places. These sandwiches are not what I would call “diabetic friendly” as the bread rolls are massive, clocking in an estimated 100-120 grams of carbohydrates for my preferred roll, Dutch Crunch. What happened next was surprising. In my experience eating anything over 100 grams of carbohydrates in a single meal, I would always Continue reading >>

Apidra Vs. Humalog/novolog

Anyone out there on Apidra? Why did you make the switch from Humalog or Novolog? Is it any different? If so, how? Did your doctor recommend Apidra, or did you bring it up? I’m wondering if the Apidra hullabaloo is just a way for Sanofi-Aventis to build profit margins? Is it worth making the switch? Why (not)? I’d love to hear your experiences. I’m thinking about switching. Continue reading >>

Switching From Apidra To Novolog

you think differently. However, I also use a 120 Symlin dose with each meal. If I switch to Novolog ...My PCP has been asked by my insurance provider to change my insulin from Humalog to Novolog to save ... Is there a problem switching between Humalog and Novolog on an almost daily basis? ... I am now required by Coventry to use Novolog instead of Humalog . I have been a type 1 for 55 years. If they are equal in quality and etc. Why are they cheaper? It does not seem possible to create an equal at half ... I am having a conflict with my nurse director. Im an "older" LPN x 40 yrs, with a pretty good handle on diabetes . A physicians order reads Novolog 70/30 mix 90 units (NINETY) TID. My personal belief ... from apidra than novolog..side effects are less on apidra. However the cost is prohibitive and punitive ... was taken off Novolog......high weight gain, Nausea, ineffective action to reduce bloodsugar levels below ... I have an old pen of apidra....my doctor Took me off insulin put me on invocanna, however my blood ... a year since I took apidra, can I do a sliding scale tog get my sugar down? Please help....I forgot how ... A year ago maybe little longer I started taking Novolog, at first I noticed some hair loss ... effect of Novolog? ... How safe is using Novolog while on Bydureon? I WAS RECENTLY PUT ON BYDUREON AND I NOTICED THAT MY DR DIDN T REFILL MY NOVOLOG. IS IT SAFE TO SAY THAT I M NOT SUPPOSED TO BE USING THE NOVOLOG? I HAVE BEEN DOING 45 UNITS OF LANTUS 2X DAILY AND MY BS ... after each meal and thats 15 units (novolog). the slow i take at night b4 bed and i take 110 units of( lantus) . tonight I mixed them up and gave myself 110 units of novolog . am I in danger? ... to MRI contrast. I have been diabetic for 10 years normally requiring about 5 does of No Continue reading >>

The Switch-a-roo: Novolog Day 2,297 / Apidra Day 1

The Switch-A-Roo: Novolog Day 2,297 / Apidra Day 1 Have I mentioned recently how utterly impossible blood sugars have been over here? If this is a growth spurt, it is the MUTHA of all growth spurts. The past 2 weeks have been a blur of high blood sugars. I think something happens to my brain when were in a rut like this. Its hard to concentrate, and I find myself lost in a sea of numbers, trying to differentiate between times and basals and ratios and carbs and on and on and on. Dont get me wrong. I HATE LOWS. But I can fix a low lickety split. Highs like this? I feel like Im being pelted with snowballs from every angle, and all I can do is run for cover behind a tree, trying my best toshieldboth of us and every organ in her body from a fate of doom. For awhile now, Ive been following some DOC Peeps who have been using Apidra . I scored a bottle to trial, but was waiting until the winter break from school so I could hover. Something happened. She was 350 around 9 pm, and I fell off my rocker. That was it. I couldnt stand it any longer. Sure, it was Thanksgiving, but she hadnt really eaten out of the ordinary if anything, she had eaten LESS than usual. Her numbers shouldnt have been so stinkin wonky. Period. We yanked her old site, filled the pump with Apidra, perused Facebook for a little feedback about Duration of Insulin Action times, inserted a new Dexcom sensor, and hit the ground running. Disclaimer: Switching up your/your childs lifeline right before going to sleep by using an insulin shes never been exposed to when you know that Dead In Bed Syndrome is a very real threat , and recent stats suggest that 1 in 20 people with Type 1 Diabetes die from hypoglycemia is not something I would everrecommenddoing. Its a dumb idea, so dont do it. You should ALWAYS consult y Continue reading >>

Information Regarding Insulin Storage And Switching Between Products In An Emergency

en Español Insulin Storage and Effectiveness Insulin for Injection Insulin from various manufacturers is often made available to patients in an emergency and may be different from a patient's usual insulin. After a disaster, patients in the affected area may not have access to refrigeration. According to the product labels from all three U.S. insulin manufacturers, it is recommended that insulin be stored in a refrigerator at approximately 36°F to 46°F. Unopened and stored in this manner, these products maintain potency until the expiration date on the package. Insulin products contained in vials or cartridges supplied by the manufacturers (opened or unopened) may be left unrefrigerated at a temperature between 59°F and 86°F for up to 28 days and continue to work. However, an insulin product that has been altered for the purpose of dilution or by removal from the manufacturer’s original vial should be discarded within two weeks. Note: Insulin loses some effectiveness when exposed to extreme temperatures. The longer the exposure to extreme temperatures, the less effective the insulin becomes. This can result in loss of blood glucose control over time. Under emergency conditions, you might still need to use insulin that has been stored above 86°F. You should try to keep insulin as cool as possible. If you are using ice, avoid freezing the insulin. Do not use insulin that has been frozen. Keep insulin away from direct heat and out of direct sunlight. When properly stored insulin becomes available again, the insulin vials that have been exposed to these extreme conditions should be discarded and replaced as soon as possible. If patients or healthcare providers have specific questions about the suitability of their insulin, they may call the respective manufacturer a Continue reading >>

Switching From Novolog To Apidra

Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. My pump has arrived, I am waiting for a pump trainer. That won't be until at least next week, we are really snowed in here in South Dakota. When I start pumping, it will be with Apidra, I am now on 99 units of 70/30 novolog. I know the pump will take less, from the other thread (Thanks!), I have read that it takes higher doses of Apidra than it would novolog. Any one make that switch and can confirm this? How much more did you need? Well, I can't be much help in determining doses going from MDI Novolog to pumping Apidra, but I can tell you that when I switched from MDI Novolog to MDI Apidra, my doses initially decreased until my body seemed to adapt, but now I'm pretty much back to the same doses/boluses I was using with Novolog - maybe a teeny tiny bit lower but it's miniscule. Definitely not an increase though. I'm not sure if there's a typical trend you should expect (increase like you said) and I'm an anomaly, or if everyone's reaction to it will be different. I just switched a week ago and the dosing was 100% the same. I haven't changed anything by changing to APidra. So I'd just go with the numbers they initially give you and tweak from there. My endo gave me samples of Apidra and Novolog to try out. During my testing, the amount did not change from Humalog to Apidra to Novolog. Apidra did leave me with much less redness around the infusion site, so I asked for a prescription for Apidra. At the end of my testing, I caught a real bad cold that went into pneumonia. I might as well have been pumping saline as Apidra. BG's shot up to low 300's high 200's and would not come down. Today I sta Continue reading >>

Test Driving Insulin

How many insulins have you tried? If you're like most people, you only switch to something new when a better generation comes out, such as when Regular upgraded to Humalog or when NPH upgraded to Lantus. But when it comes to comparing insulin in the same family, say Humalog versus Novolog or Lantus versus Levemir, most of us only try something new when something goes very wrong, such as burning at the injection site. Yech... But what really differentiates them anyway? On the outside, there aren't many distinct differences between Humalog, Novolog and Apidra. They are all rapid-acting insulin designed to enhance upon the classic Regular. They have a quick onset (between 10 and 15 minutes) and are generally are out of your system in a couple of hours. But if you ask an individual, "Which insulin do you use?" you'll get a variety of answers and a variety of reasons. When Apidra came to market in 2004, it claimed the title of speed champion. While Humalog was fast, and Novolog was faster, Apidra was the fastest, according to manufacturer Sanofi-Aventis. Actually, there is no scientific evidence that there are any major difference between the different brands of rapid-acting insulin. "I have seen zero reliable research (ie, not conducted by an insulin company) showing any difference in action times," says expert John Walsh, PA, CDE, and author of Pumping Insulin. But many people — including many Apidra users like myself! — still claim otherwise. We surveyed the folks at TuDiabetes to get their impressions of how the different insulins have affected their blood sugar, and several people responded with interesting feedback about the new kid on the block, Apidra. Linzie, a type 1, switched to Apidra when she went on her insulin pump. "Apidra works really quick compared to t Continue reading >>

Update: Switch From Apidra To Novolog

This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies. Learn More. Well, this is typical. After a pharmacy error resulted in my having 40 (!) non-returnable vials of Apidra, I've switched back to Novolog and everything seems a whole lot smoother. I only made the switch 2 days ago so it could be a fluke. I've had highs in the 200s each day after (cereal) breakfast because my DIA on Novolog is 5 hours, but aside from that I've been in range. That's better than on Apidra. If I do stick with this, I'll probably keep Apidra handy and just give myself a shot of that when I want to eat cereal. I've been using Apidra for around 8 months, wanting to give it a fair trial, but I think at this point I will just give in and accept that for whatever reason Novolog works better in my body. It's a shame because I did like the 3 hour DIA of Apidra - I just don't think it was worth it for all the other problems. Emma - We're in the same place as you are. We just made the switch back to Novolog from Apidra last month, and everybody is so much happier. I do miss the responsiveness of Apidra, but I love the fact that my son isn't yo-yoing up and down all day. I recognize that I probably could have worked harder to figure Apidra out, but I put in a valiant effort for 5 months and got nowhere. As a bonus, my little man's moods have evened out quite a bit on Novolog, probably as a result of the more consistent numbers. I am glad to have tried Apidra out, but I won't be switching back for a while! Continue reading >>