Somogyi Effect Vs Dawn Phenomenon Usmle

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Diabetes Mellitus

Diabetes mellitus (DM) describes a group a metabolic diseases that are characterized by chronic hyperglycemia (elevated blood glucose levels). The two most common forms are type 1 and type 2 diabetes mellitus. Type 1 is the result of an autoimmune response that triggers the destruction of insulin-producing β cells in the pancreas and results in an absolute insulin deficiency. Type 2, which is much more common, has a strong genetic component as well as a significant association with obesity and sedentary lifestyles. Type 2 diabetes is characterized by insulin resistance (insufficient response of peripheral cells to insulin) and pancreatic β cell dysfunction (impaired insulin secretion), resulting in relative insulin deficiency. This form of diabetes usually remains clinically inapparent for many years. However, abnormal metabolism (prediabetic state or impaired glucose intolerance), which is associated with chronic hyperglycemia, causes microvascular and macrovascular changes that eventually result in cardiovascular, renal, retinal, and neurological complications. In addition, type 2 diabetic patients often present with other conditions (e.g. hypertension, dyslipidemia, obesity) t Continue reading >>

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Popular Questions

  1. bangbong2000

    I guess they have to give us tips in the question like in case of somogyi pt morning hyperglycemia not improving with restriction of carbohydrate food before bed... Anyone can give me more idea?

  2. sonu.agarwall

    i read abt it somewer man....not sure wer....sum wer in my final year texts.....will post as soon as i find it....somogyi is sumthing in middle of night due to medications n dawn phenomenon is in early mrng related to counter regulatory hormones...sumthing like that

  3. docnas

    somogyi = rebound hyperglycemia due to hypoglycemia because of too much insulin given before sleeping
    dawn phenom is due to homones being released according to circadian rhythm main hormone noted is GH. this causes a hyperglycemic state.

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