Types Of Diabetes Mellitus
Diabetes mellitus (or diabetes) is a chronic, lifelong condition that affects your body's ability to use the energy found in food. There are three major types of diabetes: type 1 diabetes, type 2 diabetes, and gestational diabetes. All types of diabetes mellitus have something in common. Normally, your body breaks down the sugars and carbohydrates you eat into a special sugar called glucose. Glucose fuels the cells in your body. But the cells need insulin, a hormone, in your bloodstream in order to take in the glucose and use it for energy. With diabetes mellitus, either your body doesn't make enough insulin, it can't use the insulin it does produce, or a combination of both. Since the cells can't take in the glucose, it builds up in your blood. High levels of blood glucose can damage the tiny blood vessels in your kidneys, heart, eyes, or nervous system. That's why diabetes -- especially if left untreated -- can eventually cause heart disease, stroke, kidney disease, blindness, and nerve damage to nerves in the feet. Type 1 diabetes is also called insulin-dependent diabetes. It used to be called juvenile-onset diabetes, because it often begins in childhood. Type 1 diabetes is an autoimmune condition. It's caused by the body attacking its own pancreas with antibodies. In people with type 1 diabetes, the damaged pancreas doesn't make insulin. This type of diabetes may be caused by a genetic predisposition. It could also be the result of faulty beta cells in the pancreas that normally produce insulin. A number of medical risks are associated with type 1 diabetes. Many of them stem from damage to the tiny blood vessels in your eyes (called diabetic retinopathy), nerves (diabetic neuropathy), and kidneys (diabetic nephropathy). Even more serious is the increased risk of hea Continue reading >>
Type 1 And Type 2 Diabetes: What’s The Difference?
There are two main types of diabetes: type 1 and type 2. Both types of diabetes are chronic diseases that affect the way your body regulates blood sugar, or glucose. Glucose is the fuel that feeds your body’s cells, but to enter your cells it needs a key. Insulin is that key. People with type 1 diabetes don’t produce insulin. You can think of it as not having a key. People with type 2 diabetes don’t respond to insulin as well as they should and later in the disease often don’t make enough insulin. You can think of this as having a broken key. Both types of diabetes can lead to chronically high blood sugar levels. That increases the risk of diabetes complications. Both types of diabetes, if not controlled, share many similar symptoms, including: frequent urination feeling very thirsty and drinking a lot feeling very hungry feeling very fatigued blurry vision cuts or sores that don’t heal properly People with type 1 diabetes may also experience irritability and mood changes, and unintentionally lose weight. People with type 2 diabetes may also have numbness and tingling in their hands or feet. Although many of the symptoms of type 1 and type 2 diabetes are similar, they present in very different ways. Many people with type 2 diabetes won’t have symptoms for many years. Then often the symptoms of type 2 diabetes develop slowly over the course of time. Some people with type 2 diabetes have no symptoms at all and don’t discover their condition until complications develop. The symptoms of type 1 diabetes develop fast, typically over the course of several weeks. Type 1 diabetes, which was once known as juvenile diabetes, usually develops in childhood or adolescence. But it’s possible to get type 1 diabetes later in life. Type 1 and type 2 diabetes may have simi Continue reading >>
Type 1 Vs Type 2 Diabetes (similarities And Differences) Center
Diabetes mellitus is a metabolic condition in which a person's blood sugar (glucose) levels are too high. Over 29.1 million children and adults in the US have diabetes. Of that, 8.1 million people have diabetes and don't even know it. Type 1 diabetes (insulin-dependent, juvenile) is caused by a problem with insulin production by the pancreas. Type 2 diabetes (non-insulin dependent) is caused by: Eating a lot of foods and drinking beverages with simple carbohydrates (pizza, white breads, pastas, cereals, pastries, etc.) and simple sugars (donuts, candy, etc.) Consuming too many products with artificial sweeteners (We found out that they are bad for us!) Lack of activity Exercise Stress Genetics While the signs and symptoms of both types of diabetes are the same, which include: However, the treatments are different. Type 1 diabetes is insulin dependent, which means a person with this type of diabetes requires treatment with insulin. People with type 2 diabetes require medication, lifestyle changes like eating a healthy diet, and getting regular exercise. Read more: Type 1 vs Type 2 Diabetes (Similarities and Differences) Article What Is Type 2 Diabetes? Type 2 diabetes can affect all people, regardless of age. Early symptoms of type 2 diabetes may be missed, so those affected may not even know they have the condition. An estimated one out of every three people within the early stages of type 2 diabetes are not aware they have it. Diabetes interferes with the body's ability to metabolize carbohydrates for energy, leading to high levels of blood sugar. These chronically high blood sugar levels increase a person's risk of developing serious health problems. Potential Consequences of High Blood Sugar Nerve problems Vision loss Joint deformities Cardiovascular disease Diabetic Continue reading >>
Type 1 And Type 2 Diabetes: What Do They Have In Common?
Abstract Type 1 and type 2 diabetes frequently co-occur in the same families, suggesting common genetic susceptibility. Such mixed family history is associated with an intermediate phenotype of diabetes: insulin resistance and cardiovascular complications in type 1 diabetic patients and lower BMI and less cardiovascular complications as well as lower C-peptide concentrations in type 2 diabetic patients. GAD antibody positivity is more common in type 2 diabetic patients from mixed families than from common type 2 diabetes families. The mixed family history is associated with more type 1-like genetic (HLA and insulin gene) and phenotypic characteristics in type 2 diabetic patients, especially in the GAD antibody-positive subgroup. Leaving out the extreme ends of diabetes phenotypes, young children progressing rapidly to total insulin deficiency and strongly insulin-resistant subjects mostly with non-Europid ethnic origin, a large proportion of diabetic patients may have both type 1 and type 2 processes contributing to their diabetic phenotype. Continue reading >>
Types 1 And 2 Diabetes: A Comparison And Contrast
Paragraph 1 Diabetes mellitus is a condition in which the pancreas no longer produces enough insulin or when cells stop responding to the insulin that is produced so that glucose in the blood cannot be absorbed into the cells of the body. Diabetes can be classified according to two types; Type 1 and Type 2 diabetes. Approximately, 14 million Americans (about five percent of the population) have some form of diabetes. In the United States, diabetes almost causes 200,000 deaths every year ("Diabetes", 2001). Type 1 diabetes, also known as insulin-dependent diabetes mellitus (IDDM), usually affects people who are under 30. In contrast, type 2 diabetes, also called non-insulin dependent diabetes mellitus (NIDDM), affects people who are usually over 40 (Thomas, 1997). Type 1 diabetes may account for five to ten percent of all diagnosed cases of diabetes, including 11,000 to 12,000 children who suffer each year. On the other hand, type 2 diabetes may account for 90 to 95 percent of all diagnosed cases of diabetes (Karam & Masharani, 2002). A comparison of types 1 and 2 diabetes reveals major similarities and differences in causes, symptoms, complications, and treatment. Paragraph 2 Types 1 and 2 diabetes are two diseases that can be compared and contrasted according to their causes. Type 1 diabetes is similar to type 2 diabetes in that they are genetic diseases. Recently, researchers have been attempting to locate the genes for diabetes. As a part of the genome project in which researchers around the world are attempting to map the entire gene structure of all the human chromosomes, they have isolated 18 genes that appear to be involved in the production of type 1 diabetes. Not all of these genes have equal potency. Two of them appear to be most potent, some others are least Continue reading >>
5 Differences Between Type 1 And Type 2 Diabetes
5 Differences Between Type 1 and Type 2 Diabetes Diabetes is one of the oldest and yet most misunderstood diseases. There are many different types of diabetes, however, the most common ones are Type 1 and Type 2 diabetes. They differ based on how they are caused and treated. But the main similarity that Type 1 and Type 2 diabetes do share is elevated blood glucose levels. The inability to control blood glucose levels will also cause the same symptoms and complications in both. Type 1 Diabetes is an autoimmune disease. The immune system mistakes the insulin producing cells in the pancreas as invaders and attacks them. Once this happens, the cells can no longer produce insulin and a person is therefore insulin dependent for life in order to stay alive. Type 2 Diabetes is a metabolic condition. Its when the body doesnt produce enough insulin or becomes resistant to it. The condition can sometimes be controlled with proper diet and exercise, or a drug to enhance sensitivity to the bodys insulin production. But sometimes natural insulin production is insufficient and insulin injections are then needed to sustain normal blood glucose levels. People with Type 1 Diabetes DO NOT produce insulin. Insulin is a hormone that a working pancreas releases to allow glucose (sugar) from carbohydrates thats eaten to be absorbed for energy. Without this hormone, the body starves and eventually dies. This is why everyday insulin injections is necessary for survival and early diagnosis detection is SO IMPORTANT. Insulin is normally still produced by people with Type 2 Diabetes. In order to regain sensitivity to insulin, proper diet and exercise is recommended. In some cases, insulin injections are needed to keep diabetes in better control. Currently, there is no prevention for Type 1 Diabet Continue reading >>
Type 1 Diabetes Vs. Type 2 Diabetes
Diabetes affects over 29 million people in the United States, and 1 in 4 of those affected are unaware that they have diabetes. Type 1 diabetes is usually diagnosed in younger people and occurs when the body cannot produce enough insulin. In type 2 diabetes, the body cannot use the insulin it produces. This disease, frequently related to obesity, a sedentary lifestyle, and genetics, is most often diagnosed in adults, but incidence rates are increasing among teens in America. Comparison chart Type 1 Diabetes versus Type 2 Diabetes comparison chart Type 1 Diabetes Type 2 Diabetes Definition Beta cells in pancreas are being attacked by body's own cells and therefore can't produce insulin to take sugar out of the blood stream. Insulin is not produced. Diet related insulin release is so large and frequent that receptor cells have become less sensitive to the insulin. This insulin resistance results in less sugar being removed from the blood. Diagnosis Genetic, environmental and auto-immune factors, idiopathic Genetic, obesity (central adipose), physical inactivity, high/low birth weight, GDM, poor placental growth, metabolic syndrome Warning Signs Increased thirst & urination, constant hunger, weight loss, blurred vision and extreme tiredness, glycouria Feeling tired or ill, frequent urination (especially at night), unusual thirst, weight loss, blurred vision, frequent infections and slow wound healing, asymptomatic Commonly Afflicted Groups Children/teens Adults, elderly, certain ethnic groups Prone ethnic groups All more common in African American, Latino/Hispanic, Native American, Asian or Pacific Islander Bodily Effects Beleived to be triggered autoimmune destruction of the beta cells; autoimmune attack may occur following a viral infection such as mumps, rubell Continue reading >>
Similarity Of The Impact Of Type 1 And Type 2 Diabetes On Cardiovascular Mortality In Middle-aged Subjects
OBJECTIVE—To compare the risk of cardiovascular disease (CVD) death and the impact of hyperglycemia on the risk of CVD mortality associated with type 1 diabetes to that associated with type 2 diabetes. RESEARCH DESIGN AND METHODS—The study comprised 173 participants with type 1 diabetes, 834 participants with type 2 diabetes, and 1,294 nondiabetic participants, aged 45–64 years at baseline and free of CVD. The age of onset of diabetes was >30 years in both diabetic groups. RESULTS—During an 18-year follow-up, 86 participants with type 1 diabetes, 567 participants with type 2 diabetes, and 252 nondiabetic participants died. CVD mortality rates per 1,000 person-years were 23.1 (95% CI 16.9–31.9) in type 1 diabetic, 35.3 (30.8–40.4) in type 2 diabetic, and 4.6 (3.8–5.7) in nondiabetic participants. Adjusted hazard ratios for CVD mortality in participants with type 1 diabetes versus no diabetes was 3.6 (95% CI 2.2–5.7) in men and 13.3 (6.9–22.5) in women and in participants with type 2 diabetes versus no diabetes 3.3 (2.5–4.5) in men and 10.1 (6.7–17.4) in women. An increment of 1 unit (%) of GHb increased CVD mortality by 52.5% (95% CI 28.4–81.3) in type 1 diabetic subjects and by 7.5% (4.3–10.8) in type 2 diabetic participants. CONCLUSIONS—The impact of type 1 and type 2 diabetes on CVD mortality was similar. The effect of increasing hyperglycemia on the risk of CVD mortality was more profound in type 1 than in type 2 diabetic subjects. Diabetes is a heterogeneous group of disorders characterized by high blood glucose levels (1). Type 1 diabetes is primarily due to destruction of pancreatic β-cells, resulting in absolute insulin deficiency. Type 2 diabetes, accounting for >80% of all diabetes cases globally, is characterized by insulin resista Continue reading >>
- Mortality and Cardiovascular Disease in Type 1 and Type 2 Diabetes
- Early Glycemic Control and Magnitude of HbA1c Reduction Predict Cardiovascular Events and Mortality: Population-Based Cohort Study of 24,752 Metformin Initiators
- Impact of metformin on cardiovascular disease: a meta-analysis of randomised trials among people with type 2 diabetes
Differences And Similarities Between Type 1 And Type 2 Diabetes
The term “diabetes” can be confusing, especially as it encompasses two different conditions, referred to as type 1 diabetes and type 2 diabetes. While the two conditions share some similarities in that they both involve the body’s production and use of insulin, as well as sharing similar symptoms, they also differ in a few very important ways. Type 1 Diabetes This type of diabetes, which accounts for only 5 to 10% of all diabetes cases, is also sometimes referred to as insulin-dependent diabetes or juvenile-onset diabetes, and is particularly scary because it is not curable or preventable. It has been called juvenile-onset diabetes because the symptoms usually start during childhood or adolescence, with people usually completely unaware that they even have it until they seek medical attention for symptoms or illness related to a spike in their blood sugar. In type 1 diabetes, the body’s immune system attacks the cells which produce insulin, eventually completely eliminating the production of insulin entirely, without which the body’s cells cannot absorb the sugar that they need to produce energy. Common symptoms of high blood sugar (hyperglycemia) include dry mouth, excessive thirst, frequent urination or nighttime urination, blurred vision, weight loss, dry and itchy skin, and general fatigue. Those with type 1 diabetes will also experience periods of low blood sugar (hypoglycemia), which has symptoms similar to high blood sugar but which also include a rapid heartbeat, sudden mood changes or anxiety, pale skin, headaches, hunger, trouble concentrating, excessive sweating, and shaking. Type 2 Diabetes This type of diabetes, which accounts for the majority of all diabetes cases, has also been called adult-onset diabetes or non-insulin-dependent diabetes. Despi Continue reading >>
Type 1 And Type 2 Diabetes May Be Caused By The Same Underlying Mechanism
Through the years, there have been a variety of research initiatives that have looked at type 1 and type 2 diabetes as closely related conditions. Some even consider the two as being a part of a spectrum – where they are essentially, one and the same. This is called ‘the Accelerator Hypothesis‘.1 This hypothesis studies the relationship of BMI and age of diagnosis, and suggests that both conditions may be triggered by a degree of ‘fatness,’ and the same basic risk factors. As controversial as this research is, through the years, the data have remained consistent with the hypothesis. Amylin Now, new research out of Manchester University and Auckland2, suggests that type 1 and type 2 diabetes have the same underlying mechanism: they are both caused by the toxic clumping up of the hormone amylin around the pancreas’ insulin producing cells. This finding could lead to slowing down or a reversal for both forms of diabetes, with the development of drugs that could stop or slow down the forming of these clumps. Amylin is a hormone that is normally produced alongside insulin, and helps regulate our body’s satiety signals. When amylin gets produced, some of it ends up depositing around the pancreas’ beta cells which make insulin, where it then forms toxic clumps that end up destroying these insulin producing cells. When the cells die, the result is diabetes. Research published by Professor Garth Cooper (based on 20 years of work) points to this being the cause of type 2 diabetes, and there is strong evidence with these newest findings that type 1 diabetes is caused by the same mechanism. The differences tend to be in age, and in the rate of onset of the conditions – in type 1, the toxic amylin deposits occur much more rapidly. There could be potential medicines Continue reading >>
Diabetes: The Differences Between Types 1 And 2
Diabetes, or diabetes mellitus (DM), is a metabolic disorder in which the body cannot properly store and use sugar. It affects the body's ability to use glucose, a type of sugar found in the blood, as fuel. This happens because the body does not produce enough insulin, or the cells do not correctly respond to insulin to use glucose as energy. Insulin is a type of hormone produced by the pancreas to regulate how blood sugar becomes energy. An imbalance of insulin or resistance to insulin causes diabetes. Diabetes is linked to a higher risk of cardiovascular disease, kidney disease, vision loss, neurological conditions, and damage to blood vessels and organs. There is type 1, type 2, and gestational diabetes. They have different causes and risk factors, and different lines of treatment. This article will compare the similarities and differences of types 1 and 2 diabetes. Gestational diabetes occurs in pregnancy and typically resolves after childbirth. However, having gestational diabetes also increases the risk of developing type 2 diabetes after pregnancy, so patients are often screened for type 2 diabetes at a later date. According to the Centers for Disease Control and Prevention (CDC), 29.1 million people in the United States (U.S.) have diabetes. Type 2 diabetes is much more common than type 1. For every person with type 1 diabetes, 20 will have type 2. Type 2 can be hereditary, but excess weight, a lack of exercise and an unhealthy diet increase At least a third of people in the U.S. will develop type 2 diabetes in their lifetime. Both types can lead to heart attack, stroke, nerve damage, kidney damage, and possible amputation of limbs. Causes In type 1 diabetes, the immune system mistakenly attacks the insulin-producing pancreatic beta cells. These cells are destro Continue reading >>
What's The Difference Between Type 1 And Type 2 Diabetes?
Type 1 and type 2 diabetes share the problem of high levels of blood sugar. The inability to control blood sugar causes the symptoms and the complications of both types of diabetes. But type 1 diabetes and type 2 diabetes are two different diseases in many ways. According to the latest (2014) estimates from the Centers for Disease Control and Prevention (CDC), 29.1 million people, or 9.3 percent of the U.S. population, have diabetes. Type 1 diabetes affects just 5 percent of those adults, with type 2 diabetes affecting up to 95 percent. Here’s what else you need to know to be health-savvy in the age of the diabetes epidemic. What Causes Diabetes? "Type 1 diabetes is an autoimmune disease — the body's immune system attacks the cells in the pancreas that make insulin," a hormone, says Andjela Drincic, MD, associate professor of internal medicine in the division of diabetes, endocrinology, and metabolism at the University of Nebraska Medical Center in Omaha. The exact cause is not known, but it's probably a combination of the genes a person is born with and something in the environment that triggers the genes to become active. "The cause of type 2 diabetes is multifactorial," says Dr. Drincic. "People inherit genes that make them susceptible to type 2, but lifestyle factors, like obesity and inactivity, are also important. In type 2 diabetes, at least in the early stages, there is enough insulin, but the body becomes resistant to it." Risk factors for type 2 diabetes include a family history of the disease, a poor diet, a sedentary lifestyle, and obesity. African-Americans, Latin Americans, and certain Native American groups have a higher risk of type 2 diabetes than Caucasian Americans. Juvenile or Adult-Onset: When Does Diabetes Start? Usually, type 1 diabetes in dia Continue reading >>
Differences Between Type 1 And Type 2 Diabetes
Despite sharing a name, type 1 and type 2 diabetes are quite different. Understanding the key differences in type 1 diabetes and type 2 diabetes is critical for research into finding a way to cure, treat and prevent diabetes, but also for caring for someone with diabetes and managing your own diabetes. How these diseases begin, how they affect the body and how they are treated are all quite different. What is Type 1 Diabetes? Type 1 diabetes is the result of the human immune system mistaking the body’s beta cells, which produce insulin, for foreign cells and causing their destruction. Insulin is a protein that allows the transport of sugar into cells to provide energy. When sugar can’t get from the blood into the cells, the cells have no access to the glucose they need and cannot function correctly. The composition of our blood also gets off balance, with high blood sugar levels leading to detrimental effects on other organs of the body. Injecting synthetic insulin solves this problem because it keeps blood glucose levels in the right range and helps glucose reach our cells. What is Type 2 Diabetes? Although type 2 diabetes is much more common than type 1, the causes for it aren’t fully understood. What doctors and scientists do know is that excess weight, inactivity, age and genetic makeup contribute to development of the disease. Patients with type 2 diabetes make insulin, but the cells in the body cannot respond to it adequately so they cannot take up glucose. Later on, especially when treatment fails, type 2 diabetes is aggravated by exhausted beta cells, decreasing their insulin production resulting in further increases in blood sugar levels. Since beta cells aren’t killed off in type 2 diabetes, at least initially, blood sugar levels often become elevated Continue reading >>
Differences Between Type 1 And Type 2
Tweet Whilst both type 1 and type 2 diabetes are characterised by having higher than normal blood sugar levels, the cause and development of the conditions are different. Confused over which type of diabetes you have? It's not always clear what type of diabetes someone has, despite what many people think. For instance, the typical assumption is that people with type 2 diabetes will be overweight and not inject insulin, while people with type 1 diabetes will be, if anything, underweight. But these perceptions just aren't always true. Around 20% of people with type 2 diabetes are of a healthy weight when diagnosed, and many of them are dependent on insulin. Similarly, people with type 1 diabetes will in some cases be overweight. Because both types of diabetes can be so varied and unpredictable, it's often difficult to know which type of diabetes someone has. It's not safe to assume that an overweight person with high blood glucose levels has type 2 diabetes, because the cause of their condition might in fact be attributable to type 1. In some cases, when the type of diabetes is in doubt, your health team may need to carry out specialised tests to work out which type of diabetes you have. This way, they can recommend the most appropriate treatment for your diabetes. Common differences between type 1 and type 2 diabetes Despite the uncertainty that often surrounds a diagnosis of diabetes, there are a few common characteristics of each diabetes type. Please note that these differences are based on generalisations - exceptions are common. For instance, the perception of type 1 diabetes isn't strictly true: many cases are diagnosed in adulthood. This table should be seen as a rough guide to the differences between type 1 and type 2 diabetes, rather than hard and fast rules. Co Continue reading >>
Type 1 And Type 2 Diabetes: What’s The Difference?
If your child or someone you know has been recently diagnosed with type 1 diabetes, you may be wondering how the disease differs from type 2 diabetes — the form people tend to know more about. What causes type 1 versus type 2 diabetes? Are the symptoms the same? And how is each treated? Here to clear up the confusion with an overview of key differences — and similarities — between these two types of diabetes are experts Julie Settles, M.S.N., A.C.N.P.-B.C., C.E.N., a clinical research scientist at Lilly Diabetes, and Rosemary Briars, N.D., P.N.P.-B.C., C.D.E., C.C.D.C., clinical director and program co-director of the Chicago Children’s Diabetes Center at La Rabida Children’s Hospital. Causes Diabetes, or diabetes mellitus, as it’s formally known in medical terms, describes a group of metabolic diseases in which a person develops high blood glucose (blood sugar). The underlying health factors causing the high blood sugar will determine whether someone is diagnosed with type 1 or type 2 diabetes. Type 1 diabetes is an autoimmune disease in which “the body’s immune system starts to make antibodies that are targeted directly at the insulin-producing cells of the pancreas (islet cells),” explains Briars. Over time, the immune system “gradually destroys the islet cells, so insulin is no longer made and the person has to take insulin every day, from then on,” she says. As for why this happens, Settles notes, “The immune system normally fights off viruses and bacteria that we do not want in our body, but when it causes diabetes, it is because something has gone wrong and now the body attacks its own cells.” Triggering this autoimmune response is a complex mix of genetic and environmental factors that researchers are still trying to fully understand. O Continue reading >>