Rosacea And Diabetes

Rosacea Associated With Ra, Diabetes, Celiac Disease, Multiple Sclerosis

Rosacea associated with RA, diabetes, celiac disease, multiple sclerosis Egeberg A, et al. J Am Acad Dermatol. 2016;doi:10.1016/j.jaad.2015.11.004. Rosacea had a significant association with type 1 diabetes mellitus, celiac disease, multiple sclerosis and rheumatoid arthritis, according to recently published study results. Researchers in Denmark conducted a population-based, case-control study of 6,759 patients with rosacea (63.2% women; mean age, 40.2 years) and 33,795 controls matched on age, sex and calendar time. Conditional logistic regression was used to calculate ORs. Patients with rosacea had significantly increased ORs for type 1 diabetes mellitus (adjusted OR = 2.59; 95% CI, 1.41-4.73), celiac disease (aOR = 2.03; 95% CI, 1.35-3.07), multiple sclerosis (aOR = 1.65; 95% CI, 1.2-2.28) and rheumatoid arthritis (aOR = 2.14; 95% CI, 1.82-2.52). Women with rosacea had a significant association with type 1 diabetes, celiac disease, multiple sclerosis and rheumatoid arthritis, when stratified by sex. However, men with rosacea only had a significant association with rheumatoid arthritis. The investigators reported that their study was limited because they were unable to distinguish between rosacea subtypes and severities. The discovery of these new rosacea-associated autoimmune comorbidities is intriguing and may add to improved overall understanding of rosacea etiopathogenesis, the researchers wrote. Future studies are warranted to examine their underlying mechanisms and clinical consequences. by Bruce Thiel Rosacea had a significant association with type 1 diabetes mellitus, celiac disease, multiple sclerosis and rheumatoid arthritis, according to recently published study results. Researchers in Denmark conducted a population-based, case-control study of 6,759 patie Continue reading >>

Scientists Discover Clues To Rosacea Skin Ailment

Scientists Discover Clues To Rosacea Skin Ailment A new study by scientists from the US, France and Japan appears to have found what causes acne rosacea to develop, a common inflammatory skin ailment that affects the over 30s and is also known as adult acne . The research is published in the advanced online edition of the journal Nature Medicine and was led by Dr Richard L. Gallo, professor of medicine and chief of the Division of Dermatology at the University of California, San Diego (UCSD) School of Medicine and the Dermatology section of the Veterans Affairs San Diego Healthcare System. Acne rosacea is an inflammatory skin disease that affects about 14 million Americans between the age of 30 and 60 and is more common in women than in men. It is more likely to affect fair skinned people of European or Celtic descent. Rosacea is characterized by facial redness (erythema), bumps and pimples (papulopustules), and spider veins (telangiectasia). The condition is chronic and gets worse over time. It is cyclical and flares up for weeks and months and then subsides. There is no effective treatment although antibiotics are sometimes prescribed with mixed results. Triggers for rosacea usually involve anything that causes the face to become flushed such as demanding exercise, sunburn , stress , anxiety , and sudden changes in temperature like moving from a cold to a hot environment. Other triggers arise from food and drink that cause flushing such as alcohol, hot caffeine drinks (tea, coffee ), and certain spicy foods. Rosacea can even be triggered by blushing with embarrassment. The scientists found that people with rosacea have high levels of the anti microbial peptide cathelicidin in their skin and the proteins this produces are different to those found in people who do not Continue reading >>

Rosacea - Causes - Nhs.uk

The exact cause of rosacea is unknown, although a number of potential factors have been suggested. It's possible a combination of these factors may be responsible for the condition, although there isn't enough evidence to say this for certain. Some of the main factors that have been suggested are outlined below. Some experts believe abnormalities in the blood vessels of the face may be a major contributing factor for rosacea. This may explain symptoms of flushing, persistent redness and visible blood vessels. It's not known what causes these abnormalities. But sun damage may be responsible for degeneration of the elastic tissue of the skin and the dilation of blood vessels. Recent research has shown external triggers such as ultraviolet (UV) light, spicy food, alcohol (particularly red wine), exercise, stress, heat and cold can lead to theactivation of certain molecules within the skin called peptides. Increased levels of these peptides may in turn affect the immune system ornerves and blood vessels(neurovascular system) of the skin. Activation of these systems can cause dilation of blood vessels, redness and inflammation. Microscopic mites called demodex folliculorum usually live harmlessly on human skin, but people with rosacea have particularly large numbers, which may play a role in the condition. It is currently uncertain whether the mite is a cause or an effect of rosacea, although someresearchers have suggested the symptoms may be caused by the skin reacting tobacteria in the mites' faeces. Helicobacter pylori bacteria are bacteriafound in the digestive system. It's been suggested these bacteria may be a possible cause of rosacea, althougha linkhasn't been proven. One theory is the bacteria may stimulate the production of a protein called bradykinin, which is kn Continue reading >>

Gestational Diabetes And Rosacea

If this is your first visit, be sure to check out the FAQ by clicking the link above. You have to register before you can post: click the register link above to proceed. To start viewing messages, select the forum that you want to visit from the selection below. NOTE: New users have limited privileges such as No Links, Profiles, PMs, etc. until they have made a few valid (non-spammy) posts. I have had rosacea for about 8 years. A fairly mild case, nose gradually redenning, no P&P, no burning, very few flushing episodes. I used a cream a derm prescribed on/off for 5 years and never really thought about my rosacea much. Just over 3 years ago I got pregnant. About 4 months into the pregnancy I was tested for gestational diabetes. The results were borderline. I was advised to cut out sweets and exercise after every meal (which I did). The next test and subsequent ones during my pregnancy were all borderline. Looking back at pictures I can see that my rosacea started to get much worse about mid-pregnancy. By the time my baby was born my nose was beet red and I was beginning to show signs of redness in other areas. 1 year after my baby was born my rosacea went into high gear. Beet red all the time, severe dryness and many, many P&P. So, here are my questions. Could the gestational diabetes have hampered my body's ability to deal with sugar which in turn led to high blood sugar levels which then caused a blow up in my rosacea? Is the fact that my rosacea is still very bad possibly linked to a possible blood sugar problem? Should I get any tests for diabetes done? Is there any known link between diabetes and rosacea? Once my child was born I never had any other tests for diabetes. I've recently (less than 1 week ago) cut all refined and other sugar sources (e.g. honey, maple s Continue reading >>

Study Finds Rosacea Associated With Precursor To Diabetes

Study Finds Rosacea Associated with Precursor to Diabetes Researchers recently found a possible relationship between rosacea and insulin resistance a metabolic disorder that may be a precursor to diabetes as well as between rosacea and some elements of metabolic syndrome. They noted that rosacea and metabolic disorders appear to have similar pathogenic pathways. Metabolic syndrome is related to an increased risk of type 2 diabetes mellitus and coronary artery disease. Diagnosis is made by measuring glucose intolerance, insulin resistance, dyslipidemia (high cholesterol), central obesity (large waist size) and hypertension (high blood pressure), according to Dr. Asli Belli of the Kocman University Training and Research Hospital in Mugla, Turkey, and colleagues reporting in the European Journal of Dermatology. Insulin resistance was calculated according to a standard method that compares insulin and glucose levels in the blood. The researchers measured these physical parameters and others in 47 rosacea patients and 50 individuals without rosacea. The investigators found that rosacea patients were significantly more likely to have insulin resistance. In addition, some cardiovascular risk factors, including abnormal cholesterol level and high blood pressure, were also present in rosacea patients. They speculated that the potential association between rosacea and the abnormal disorders may be explained by the fact that increased cathelicidin levels, inflammatory cytokines and oxidative stress are present during the pathogenesis of both rosacea and the metabolic disorders, and suggested that further studies with larger numbers of rosacea patients be performed to confirm and further clarify their results. Although no causal relationships have been determined, there has been a Continue reading >>

Metformin And Rosacea

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community I have been taking metformin for a month and have been on the full dose (500mg x3 daily) for over a week and I'm not a happy bunny. I'm having mild acid reflux and indigestion every day and I'm feeling bloated and burpy. This has been going on for the last week or so. I also have spots on my nose. This is the most distressing symptom for me. I have Rosaeca, which means that I have red flushing on my nose and left cheek, with regular outbreaks of pustules. Red background and yellow pustules, not a fashion statement And yes it was very noticable before I started using a cream called Rosex, (a long term treatment) prescribed by the Dermatologist in July. I know my nose was noticable as I was often asked if I had a cold by colleagues or why my nose was red by some of my more neurlogically disinhibited clients. Although my dermatologist said it was very mild. But it is back - my nose is reddening again and this week I had a crop of yellow spots :cry: I have tracked down the metformin side effects and see that flushing, rashes and skin reddening is something of an issue for some people, although rare. I may be one of them :cry: I'm going to have a chat with the pharmacist about this, and I'm thinking of dropping one of the metformin and go back to 2 a day to see what happens. I will talk to the pharmacist first. I'm interested if anyone else has experienced this effect and what you did about it. Or if there is anyone else out there with Rosacea and on metformin and if this has been an issue for you :? Red nose or much better glycaemic control and faster weight loss. People can see my nose more easily than the diabetes, which I was managing much better befor Continue reading >>

New Advances In Rosacea

In the last year, two new advances in our treatment and understanding of rosacea have occurred that I am excited to share. For those of us who have spent our professional lifetime treating rosacea, its really satisfying to see pieces of the enigmatic rosacea puzzle come together. The first exciting rosacea puzzle piece is in genetics and is thanks to the new frontier of genetic mapping. Dermatologists and rosacea patients have long observed that rosacea-prone skin runs in families. Now, researchers at Stanford, working with the genetics company called 23andMe have substantiated that observation. The research shows specific similarities in the genes of people with papulopustular rosacea. This is exciting and important for two reasons. First of all, as we learn more, it will certainly help us better predict which rosacea patients will respond best to certain treatments. Secondly, it will also allow us to make connections between rosacea (a highly viable skin problem) and other more subtle health issues seen in people who have these same genetic characteristics. Already its starting to look like rosacea is not just skin deep! All of these HLA allele associations have links to other autoimmune diseases. The DRB1*03:01-DQB1*02:01-DQA1*05:01 haplotype has been associated with type I diabetes (Erlich et al., 2008), and HLA-DRB1*03:01 is associated with retinopathy in type I diabetics (Kastelan et al., 2013), a vascular proliferative disorder of the eye. Rosacea also exhibits abnormal proliferation of blood vessels including on the ocular conjunctiva. HLA-DQB1*02:01 has been associated with celiac disease in humans (Krini et al., 2012), a condition that can have skin manifestations. Celiac disease involves the small intestine, and rosacea has been associated with conditions lo Continue reading >>

9 Top Rosacea Triggers And How To Tame Them

9 Top Rosacea Triggers and How to Tame Them Just when your rosacea is under control, those red bumps and rosy glow appear out of nowhere. What caused this sudden outbreak? Heres how to tame the top 9 rosacea triggers... You really want that glass of wine. Or to spend a day outside in the sun. But if youre one of 14 million Americans with rosacea, you know what will happen if you do: Your face reddens with bumps and pus-filled pimples. Eyes tear and eyelids swell; then the itching starts. These are classic symptoms of the chronic inflammatory skin condition. But if left untreated, blood vessels can show up like lines of red ink. Remember old-time actor W.C. Fields? His ruddy skin, bulbous nose and spidery veins were partly due to an extreme case of rosacea. Fields skin problemaffects men 25 times more than women, says dermatologist Charles E. Crutchfield III, MD, medical director of Crutchfield Dermatology in Eagan, Minn. Experts dont know what causes the disorder. Its common in people with fair skin especially people from Scotland, Ireland and England and typically affects men and women older than 30. And if your parents had it, theres a greater chance youll get it too. Its important to get rosacea under control and keep skin clear so you dont have those secondary side effects, says Bruce Katz, MD, director of the Juva Skin & Laser Clinic in New York City. Its not a dangerous condition and not a hard one to control. But its a challenge, because many factors set off a red skin response and they vary from one person to the next. Rarely is everyone [set off] by everything on the list, Dr. Crutchfield says. Stress canset off an outbreakin some; others byfavorite indulgences, like a hot bath, big mug of coffee or a long run. The key is to find out which triggers are yours, Continue reading >>

Out Of Control Rosacea And Diabetes

I am going through a frustrating time right now... I was diagnosed with rosacea a few months ago, but it has been getting progressivly worse and it now covers over 2/3 of my face. aside from the redness i have sores and white heads all over my face. It looks horrible and i am very embarrassed to be seen right now. The problem is that my dermatologist doesn't want to agressivly treat it because i am a diabetic who is having blood glucose control issuses and that is what is causing the rosacea to be as bad as it is right now. So what I am wondering is if there are any ideas that anyone has to help me gain control of this on my own... I currently use metrogel and a sulfur lotion from my doc. I am sorry that you have the double whammy of rosacea and diabetes. Does this mean you cannot take antibiotics? I ask because they seem to be the best treatment to use for bringing the rosacea under control. There is a low dose doxoycycline (Oracea) that might be okay for you to use as it is below the antibiotic level but many have found it very effective in treatment of rosacea. You could check that out with your doctor. You might also ask your dermatologist about Finacea. It is an topical ointment that many people have had used with good results. I use it and metrogel sort of intermittently and I think Finacea may act a little quicker to heal up the red bumps. Both the metrogel and sulphur that you are using are acceptable treatments but be aware that it can be several weeks before you see much improvement. I remember the days of having so many red bumps on my face that I did not want to be seen in public. Now, after a year or more of treatment, I still have times when I get a few bumps but nothing like when I first was diagnosed with rosacea. Things do get better. I actually am on Continue reading >>

Sugar And Rosacea - Carbohydrate Trigger Avoidance - Rrdi Member Forum

Note: The article below is based upon a chapter in Rosacea 101: Includes the Rosacea Diet by permission of the author: Sugar is the fuel that burns the inflammation in rosacea. Think of the fire triangle: Heat, Fuel, and Oxygen. Sugar is like adding some very combustible fuel to the burning inflammation of rosacea. Reduce the fuel and the fire is reduced. To understand why sugar has a role in rosacea you have to understand the affect high glycemic sugar has on human health. Sugar and spice and everything nice. Sugar is not nice. The above two statements cannot be both true. Mom and the processed food industry conditioned you that sugar is nice. (See Appendix WThe Diet Authority) Sugar is not nice. Sugar is toxic. Sugar triggers the rosacea inflammation. Sugar Busters! by H. Leighton Steward, Morrison C. Bethea, M.D., Samuel S. Andrews, M.D., and Luis A Balart, M.D. states on page 17 that SUGAR IS TOXIC! Three of the authors are medical doctors and recommend a low-sugar diet, avoiding carbohydrate with a high glycemic index . Do you get it? Medical doctors are saying that sugar is toxic. How can they write a book stating that sugar is toxic and still be licensed physicians ? That is because it is true, sugar is cumulatively toxic over time. William Dufty summarizes the toxic effect of sugar in his book, Sugar Blues, when he kicked the habit. Dufty threw all the sugar in his kitchen out and just ate grains and vegetables. He wrote, In about forty eight hours, I was in total agony, overcome with nausea, with a crashing migraine. If pain was a message, this was a long one, very involved, intense but in code. It took hours to break the code. I knew enough about junkies to recognize reluctantly my kinship with them. I was kicking cold turkey, the thing they talked about with Continue reading >>

A Rosacea By Any Other Name

Based on the nature of our bodies and the fact that many diabetics are diagnosed after exhibiting specific symptoms, I think it’s safe to say that diabetes is not just a label or category, but a disease with a distinct physical reality. But labels are important these days; think of how much time the courts spend defining “disability,” “enemy combatant,” and “marriage.” So it seems appropriate to give some real consideration to what we’re calling this condition. Are you a diabetic? Or do you have diabetes? Do you specify the type? Do you capitalize the “D”? Does it bother you if someone else does differently? Personally, I don’t usually capitalize, unless I’m specifically announcing, title-like, that “I have Diabetes.” I find I have no particular preference between “I am a diabetic,” and “I have diabetes”– but the fact that either works seems strange to me. After all, it’s not every disease that you can either be or have: you can have cancer, but you wouldn’t say you are cancerous, and you might have hepatitis, but you wouldn’t be hepatastic. Indeed, it seems to be a particular subset of diseases that can be either possessed nouns or adjectives: I have asthma/I am asthmatic, I have autism/I am autistic, I have epilepsy/I am epileptic, I have anorexia/I am anorexic, and so on. Oh. That’s right. I have a non-terminal, chronic illness. It’s part of who I am now, not just a passing possession. (Similarly, comparing Google results implies that in Spanish, the more permanent copular verb “ser” is used to say one is diabetic, rather than the more transient “estar”. Any Spanish speakers out there to confirm?) But that raises a question- if you have gestational diabetes, would you be considered a diabetic? What about Type II Continue reading >>

Don't Bring Up Diabetes, Doctor - Diabetes Self-management

Well, you wanted to know about my trip to the dermatologist today and how things turned out. So let me tell you First, I was the youngest person in the waiting room by a good 30 years. Second, its amazing, but there was nothing said about my diabetes . No mention of it. No questions that incorporated my self-management or my diagnosis or blood glucose levels or anything whatsoever to maybe trace my care of myself alongside what was going on with my skin. Maybe it doesnt matter, but then again (and this is based solely on generalized hearsay about dermatologists), maybe the doctor didnt consult my chart. She only asked generalized questions about the issues I brought up. So maybe they dont feel its necessary to look into my medical history? Could diabetes not really be on a dermatologists radar? Thatd be strange, because I find that everyone in the medical community to this point, from primary-care physician to endocrinologist (obviously) to podiatrist, even dentist to psychiatrist to phlebotomist, has asked about the diabetes. Not a visit to date (except for today) has been diabetes-discussion free. Anything thats anything to do with my body has in some way involved the diabetes. Third, I learned, during the examination, that the little things on my forehead that Kathryn was worried might be basal-cell carcinoma, these two or three little (2-millimeter) blips were instead what I thought they were: sebaceous hyperplasia . I cant blame Kathryn for worrying, because shes had skin cancer and is very tuned into anything amiss with her significant others skin. But when we Kathryn and I first discussed my forehead abnormalities and I agreed to see the doctor, I did some online research and self-diagnosed sebaceous hyperplasia. So, yesterday, when the medical resident came int Continue reading >>

Diabetes: 12 Warning Signs That Appear On Your Skin

Diabetes can affect many parts of your body, including your skin. When diabetes affects the skin, it’s often a sign that your blood sugar (glucose) levels are too high. This could mean that: You have undiagnosed diabetes, or pre-diabetes Your treatment for diabetes needs to be adjusted If you notice any of the following warning signs on your skin, it’s time to talk with your doctor. This skin condition often begins as small raised solid bumps that look like pimples. As it progresses, these bumps turn into patches of swollen and hard skin. The patches can be yellow, reddish, or brown. You may also notice: The surrounding skin has a shiny porcelain-like appearance You can see blood vessels The skin is itchy and painful The skin disease goes through cycles where it is active, inactive, and then active again The medical name for this condition is necrobiosis lipodica (neck-row-by-oh-sis lee-poi-dee-ka). TAKE ACTION Get tested for diabetes if you have not been diagnosed. Work with your doctor to better control your diabetes. See a dermatologist about your skin. Necorbiosis lipodica is harmless, but it can lead to complications. A dark patch (or band) of velvety skin on the back of your neck, armpit, groin, or elsewhere could mean that you have too much insulin in your blood. AN is often a sign of prediabetes. The medical name for this skin condition is acanthosis nigricans (ay-can-THOE-sis NIE-gri-cans). TAKE ACTION: Get tested for diabetes. 3. Hard, thickening skin When this develops on the fingers, toes, or both, the medical name for this condition is digital sclerosis (sclear-row-sis). On the hands, you’ll notice tight, waxy skin on the backs of your hands. The fingers can become stiff and difficult to move. If diabetes has been poorly controlled for years, it can f Continue reading >>

Study Finds Association Between Low-grade Inflammation And Rosacea

Newsroom Published on: December 22, 2017 Study Finds Association Between Low-Grade Inflammation and Rosacea A recent study conducted in Finland and published in Acta Dermatologica-Venerology finds that rosacea could be related to underlying systemic inflammation. A recent study conducted in Finland and published in Acta Dermatologica-Venerology finds that rosacea could be related to underlying systemic inflammation. Researchers found that the risk for rosacea, as well as other skin disorders, such as atopic eczema and onychomycosis (toenail fungus), increased with the presence of systemic low-grade inflammation. Systemic low-grade inflammation is a chronic condition that, while it may not present visible symptoms, contributes to the pathogenesis of many non-communicable diseases, including atherosclerosis, type 2 diabetes, and metabolic syndrome. The study analyzed data from 1930 participants in the Northern Finland Birth Cohort 1966. It consisted of individuals from 2 Finnish provinces born during that year whose health was followed regularly through questionnaires and clinical surveys regarding their health and lifestyle factors. The researchers closely identified levels of C-reactive protein (CRP), which is commonly used in clinical studies as a strong marker of inflammation. In individuals with slightly elevated blood levels of CRP, participants were 1.7 times more likely to have rosacea than those with normal levels. The researchers reported, It is noteworthy that despite the fact that the majority of the study cases had mild disease, we were nevertheless able to detect the associations with inflammation. A number of factors can impact an individuals CRP level, such as age, sex, body mass index, and other lifestyle factors. When these factors were accounted for in Continue reading >>

Rosacea Is Linked To The Liver And Type 2 Diabetes And Can Be Reversed Naturally

Rosacea Is Linked to the Liver And Type 2 Diabetes And Can Be Reversed Naturally Studies have shown that the liver is responsible for many conditions such as type 2 diabetes and are also the cause of skin conditions such as rosacea, psoriasis and more. The good news is these conditions can be reversed with these natural treatments. Whether you know it or not, you wear your diet on your face. We all do. What you eat is generally reflected on your skin. Its reflected in how dry your skin is, how red your skin is and how oily your skin is. You can buy creams, oils and other topical treatments, but the skin is always an inside job, dictated your liver. Causes of rosacea have been a mystery until recently. Rosacea is caused by the liver. Therefore, its no wonder that science has linked rosacea with insulin resistance and type 2 diabetes, which are also liver conditions. Rosacea is a type of eczema (there are many varieties) that are caused by a liver overloaded with toxins. Symptoms of rosacea may include: Facial redness. Persistent redness on the nose, cheeks and chin. The small blood vessels on your nose and cheeks can swell when you eat certain foods like chocolate, wine, tomato sauce, and dairy products. Swollen red bumps. Many people who have rosacea also develop pimples on their face that can look like acne. These bumps sometimes contain pus. Your skin may also feel hot and tender. Eye problems. About half of the people who have rosacea also experience eye dryness, irritation and swollen, reddened eyelids. Rarely, rosacea's eye symptoms precede the skin symptoms. Enlarged nose. In rare cases, rosacea will thicken the skin, specifically on the nose. This causes the nose to appear enlarged, red and swollen. Nose enlargement often occurs more often in men than in women. Continue reading >>