Janumet Side Effects Center
Janumet (sitagliptin/metformin HCl) is a combination of oral diabetes medicines for people with type 2 diabetes who do not use daily insulin injections. Janumet is not for treating type 1 diabetes. Common side effects of Janumet include: nausea, vomiting, stomach upset, diarrhea, constipation, headache, weakness, back pain, joint or muscle pain, a metallic taste in the mouth, or cold symptoms such as runny or stuffy nose, sneezing, and sore throat. Janumet does not usually cause low blood sugar (hypoglycemia). Low blood sugar may occur if Janumet is prescribed with other anti-diabetic medications. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Dosage of Janumet is individualized. Janumet is given twice daily with meals in 50 mg sitagliptin/500 mg metformin hydrochloride or 50 mg sitagliptin/1000 mg metformin hydrochloride doses. Hyperglycemia (high blood sugar) may result if you take Janumet with drugs that raise blood sugar, such as: isoniazid, diuretics (water pills), steroids, phenothiazines, thyroid medicine, birth control pills and other hormones, seizure medicines, and diet pills, or medicines to treat asthma, colds or allergies. Hypoglycemia (low blood sugar) may result if you take Janumet with drugs that lower blood sugar, such as: nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), beta-blockers, or probenecid. It may also interact with amiloride, triamterene, cimetidine, ranitidine, digoxin, furosemide, morphine, nifedipine, procainamide, quinidine, trimethoprim, or vancomycin. Tell your doctor all medications you use. During pregnancy, Janumet should be used only when prescribed. Your doctor may Continue reading >>
Skin Conditions And Diabetes: What You Need To Know
Everyone knows about the major long- and short-term complications of diabetes. But what many newly-diagnosed patients might not realize, is that skin conditions often come with having diabetes. My first exposure to skin conditions was a fungal infection. I can remember saying to the trainer that I could not have a fungal infection because my A1c was 6%. A specific over-the-counter anti-fungal ointment stopped the fungal infection process, and now I travel with this small tube just in case. I use it in the summer when I'm in the water and I develop itchy skin on my upper shoulder always in the same place. It's gone, and I'm happy. First, we want you to know that people who do not have diabetes get these skin conditions also, but as with many other complications, we tend to get them more often. About one-third of people with diabetes will have a skin disorder caused or affected by diabetes at some time. In fact, doctors report noting the presence of skin disorders before they diagnose diabetes. Second, if you think you have one of the skin conditions outlined in this article, please see your physician right away. Don't wait. Finally, we end this article with some easy ways to protect your skin when you have diabetes (either type 1 diabetes or type 2 diabetes). Skin Conditions that Can Affect People with Diabetes Bacterial Infections: People with diabetes appear to suffer more bacterial infections than the general population. There are several kinds of infections that can affect those of us with diabetes. One is a sty, which is an infection of the glands of the eyelids. A second type is a boil, which are infections of the hair follicles. Carbuncles are deep infections of the skin and the tissue underneath. Infections can also occur around the nails. We all know bacterial i Continue reading >>
Sitagliptin And Metformin (oral Route)
It is very important that your doctor check your progress at regular visits, especially during the first few weeks that you take this medicine. Blood and urine tests may be needed to check for unwanted effects. Under certain conditions, too much metformin can cause lactic acidosis. Symptoms of lactic acidosis include abdominal or stomach discomfort, decreased appetite, diarrhea, fast, shallow breathing, a general feeling of discomfort, muscle pain or cramping, and unusual sleepiness, tiredness, or weakness. If symptoms of lactic acidosis occur, you should get immediate emergency medical help. This medicine may cause hypoglycemia (low blood sugar). Low blood sugar can also occur if you delay or miss a meal or snack, exercise more than usual, drink alcohol, cannot eat because of nausea or vomiting, take certain medicines, or take this medicine with another type of diabetes medicine (eg, insulin, glimepiride, or pioglitazone). Symptoms of low blood sugar must be treated before they cause you to pass out (unconsciousness). People feel different symptoms with low blood sugar. It is important that you learn which symptoms you usually have so you can treat it quickly. Symptoms of low blood sugar include anxiety, behavior changes similar to being drunk, blurred vision, cold sweats, confusion, cool, pale skin, difficulty with thinking, drowsiness, excessive hunger, fast heartbeat, headaches that continue, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, or unusual tiredness or weakness. If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey, or sugar cubes, or drink fruit juice, non-diet soft drinks, or sugar dissolved in water. Also, check your blood for low blood sugar. Glucagon is used in emergency situations when sever Continue reading >>
In The Past I've Had Allergic Reactions To Metformin And My Current Dr. Had Me Placed On It Again. Should I Be Taking This?
Hello VMKmaggie, This situation can be very serious. No one should take a medication which they believe they are allergic. Each time body is challenged by the “allergy causing compound”, the stronger the allergic reaction will be. Any questions about being allergic to any medication allergy should be addressed in any and all ways until resolved, meaning that you, the patient, is comfortable in taking the medication. • Never ever take a medication that you feel many have caused you to have an allergic reaction until your questions are resolved. • Prescriber offices (doctors and nurses) are changing over to the electronic record. Allergy information or other information may have been omitted or entered incorrectly. • Ask the office to check your old (hard copy) records. If you know the date that the medication caused the “allergy”, please provide the dates with staff as this will help them in looking through your record. • Another thing that may have happened, is that patients sometimes report how they respond to a medication and call it an allergy, the prescribers doesn’t classify the response as an allergy but as a reaction to the medication and your response may have not have flagged as an “allergy”. • Always clearly describe your response to any medication. • The allergy alert should have also been in the dispensing pharmacy’s computer system. Any allergies and/or reactions to medications should be shared with all the pharmacies/pharmacist s that provides services to you. Pharmacists can many times more rapidly follow up with the prescriber and are an advocate for patients. • Always consult a second opinion if you continue to feel the situation unresolved. • Always keep an updated list of medications, allergies and medication procedures Continue reading >>
Rosacea-like Facial Rash Related To Metformin Administration In A Young Woman.
Rosacea-like facial rash related to metformin administration in a young woman. 1.Department of Medical and Surgical Science, Division of Internal Medicine, University "Magna Graecia"- Mater Domini Hospital of Catanzaro, Catanzaro, Italy. [email protected] BMC Pharmacology & Toxicology [08 Feb 2014, 15:3] BACKGROUND: Since the skin represents a common site of adverse drug reactions, few data are reported at this time regarding the development of skin rash during the treatment with antidiabetic drugs. CASE PRESENTATION: We report a 29-year old woman that developed a facial skin rash during the treatment with metformin. Clinical and laboratory findings excluded the presence of systemic diseases, but several diagnosis and many drugs were administered without clinical improvement. The self-dismission of metformin induced an improvement of symptoms, while the re-challenge documented an impairments of skin rash. The Naranjo probability scale suggested a probable association between metformin and skin rash and metformin was definitively dismissed. CONCLUSION: We report for the first time a non vasculitis facial skin manifestation related to metformin in a young woman. However, this case may emphasizes the need to consider the ADRs as a differential diagnosis in order to reduce medical errors and the related medical costs. Continue reading >>
About Metformin
Metformin is a medicine used to treat type 2 diabetes and sometimes polycystic ovary syndrome (PCOS). Type 2 diabetes is an illness where the body doesn't make enough insulin, or the insulin that it makes doesn't work properly. This can cause high blood sugar levels (hyperglycemia). PCOS is a condition that affects how the ovaries work. Metformin lowers your blood sugar levels by improving the way your body handles insulin. It's usually prescribed for diabetes when diet and exercise alone have not been enough to control your blood sugar levels. For women with PCOS, metformin stimulates ovulation even if they don't have diabetes. It does this by lowering insulin and blood sugar levels. Metformin is available on prescription as tablets and as a liquid that you drink. Key facts Metformin works by reducing the amount of sugar your liver releases into your blood. It also makes your body respond better to insulin. Insulin is the hormone that controls the level of sugar in your blood. It's best to take metformin with a meal to reduce the side effects. The most common side effects are feeling sick, vomiting, diarrhoea, stomach ache and going off your food. Metformin does not cause weight gain (unlike some other diabetes medicines). Metformin may also be called by the brand names Bolamyn, Diagemet, Glucient, Glucophage, and Metabet. Who can and can't take metformin Metformin can be taken by adults. It can also be taken by children from 10 years of age on the advice of a doctor. Metformin isn't suitable for some people. Tell your doctor before starting the medicine if you: have had an allergic reaction to metformin or other medicines in the past have uncontrolled diabetes have liver or kidney problems have a severe infection are being treated for heart failure or you have recentl Continue reading >>
Aukai Mi Casa Sobre Ruedas
En el 2010 lleg a este mundo Aukai. Mauri se enter de la hermosa noticia de que estaba embarazada, viajando por Indonesia en un viaje de surf con su hermano Marce y amigos. Tantas veces nos mudamos y esta vez queramos tener una casa frente al mar para recibir a Aukai. Y claro cuando uno pide algo al universoel universo te lo da! Y conseguimos nuestra casita frente al mar en Lanzarote. Ah estuvimos unos dos aos. Vinieron tuabuela Adri, tu abuelo Richard, tu bisabuela Aliciay tu ta Luli a conocerte.La ta decidi quedarse a vivir un tiempo en Lanzarote y fue hermoso tenerla cerca. Y ah estaba yo, despus de un nacimiento por cesarea y sin ser respetado, qued sentimentalmente muy daada. Feliz con mi nio pero senta no estar concectada con la madre que llevaba dentro ni con mi hijo. (esto se merece prrafo aparte, ya hablar de nuestros nacimientos) Lo que si sabemos que para Mauri y para mi el que Auki (asi lo llamamos) haya elegido nacer as fue un despertar de conciencia muy grande, una transformacin como seres humanos, l nos guia por este camino. Gracias amorcito! te amamos Disfrutamos mucho Lanzarote los tres y luego a casi un ao de Auki viajamos para argentina para que el resto de las dos familias lo conocieran. A los 4 meses volvimos a Canarias, a seguir nuestra vida en el mar. Aukai: nombre Hawaiano. Significa navegante, hombre de mar. Y asi sos, te criaste en el mar, jugando con arena, caracoles y algas. Buscando peces de colores, caminando descalzo y desnudopor las piedras. Salvaje, la naturaleza es tu habitad! como el mar, calmo y bravo a la vez..gracias por ensearnos tanto. Continue reading >>
Metformin
Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Tell your doctor if you have kidney disease. Your doctor will probably tell you not to take metformin. Also, tell your doctor if you are over 65 years old and if you have ever had a heart attack; stroke; diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment); a coma; or heart or liver disease. Taking certain other medications with metformin may increase the risk of lactic acidosis. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran). Tell your doctor if you have recently had any of the following conditions, or if you develop them during treatment: serious infection; severe diarrhea, vomiting, or fever; or if you drink much less fluid than usual for any reason. You may have to stop taking metformin until you recover. If you are having surgery, including dental surgery, or any major medical procedure, tell the doctor that you are taking metformin. Also, tell your doctor if you plan to have any x-ray procedure in which dye is injected, especially if you drink or have ever drunk large amounts of alcohol or have or have had liver disease or heart failure. You may need to stop taking metformin before the procedure and wait 48 hours to restart treatment. Your doctor will tell you exactly when you should stop taking metformin and when you should start taking it again. If you experience any of the following symptoms, stop taking metformin and call your doctor immediately: extreme tiredness, weakness, or discomfort; nausea; vomiting; stomach pain; decreased appetite; deep and rapid breathing or shortness of breath; dizzi Continue reading >>
Rosacea-like Facial Rash Related To Metformin Administration In A Young Woman
Abstract Since the skin represents a common site of adverse drug reactions, few data are reported at this time regarding the development of skin rash during the treatment with antidiabetic drugs. We report a 29-year old woman that developed a facial skin rash during the treatment with metformin. Clinical and laboratory findings excluded the presence of systemic diseases, but several diagnosis and many drugs were administered without clinical improvement. The self-dismission of metformin induced an improvement of symptoms, while the re-challenge documented an impairments of skin rash. The Naranjo probability scale suggested a probable association between metformin and skin rash and metformin was definitively dismissed. We report for the first time a non vasculitis facial skin manifestation related to metformin in a young woman. However, this case may emphasizes the need to consider the ADRs as a differential diagnosis in order to reduce medical errors and the related medical costs. Background Several drugs are able to induce the development of adverse drug reactions (ADRs), and usually the skin represents a common site of manifestation [1–5]. However, few data are reported at this time regarding the development of skin rash during the treatment with antidiabetic drugs [6–9]. Salem and coworkers [7], described a leukocytosis vasculitis with purpuric necrotizing eruption in lower legs in a young woman during metformin’s treatment. In this paper we describe for the first time a young woman that developed a rosacea-like facial skin rash during the treatment with metformin. Case presentation On December 2012, a 29-year-old woman presented to our observation for facial cutaneous rash that had appeared about 10 months earlier. She had only a past history of allergy to pen Continue reading >>
Metformin Allergy
Go to: Discussion Metformin is a commonly used antidiabetic drug.[3] The drug is considered to be safe and effective. It is particularly indicated for use in obese patients, with a metabolic syndrome[4,5] It is usually considered as a safe drug. The most common adverse effect of metformin is gastrointestinal irritation.[6] It rarely causes hypoglycemia, if it is used as a single antidiabetic drug. Nevertheless, an overdose of metformin can cause lactic acidosis. Thus, metformin is contraindicated in diabetic patients with kidney diseases and other conditions that might increase the risk of lactic acidosis. Similar to other drugs, allergy to metformin may occur. Metformin allergy is extremely rare. Leukocytoclastic vasculitis and psoriasiform drug eruption are the two most common presentations of metformin allergy.[7–9] In quoted reports,[7–9] the patients usually develop a rash within a few days of metformin administration and the skin lesions disappear after stopping the drug. In addition, resolution of skin manifestations in metformin allergy, within several days after withdrawal of the drug, and their recurrence when the drug is reintroduced is also seen.[9] As the patient had refused biopsy and other tests, this case was diagnosed as a probable case of metformin allergy. Based on the Naranjo probability assessment scale, the adverse effects were probably due to metformin. The clinical presentation of metformin allergy can occur in several forms. The mucocutaneous manifestation is the most common. In addition to leukocytoclastic vasculitis and psoriatic drug eruption, lichenoid reaction of the oral mucosa may also occur. Lamey et al. have proposed that the Grinspan's syndrome (the triad of oral lichen planus, diabetes mellitus, and hypertension) could be seen in Continue reading >>
Drug Rashes
Hypersensitivity and Inflammatory Skin Disorders Drug rashes are a side effect of a drug that manifests as a skin reaction. Typical symptoms include redness, bumps, blisters, hives, itching, and sometimes peeling, or pain. Every drug a person takes may have to be stopped to figure out which one is causing the rash. Most drug rashes resolve once the drug is stopped, but mild reactions may be treated with creams to decrease symptoms and serious reactions may require treatment with drugs such as epinephrine (given by injection), diphenhydramine, and/or a corticosteroid to prevent complications. The word "rash" refers to changes in skin color (such as redness) and/or texture (such as bumps or swelling). Many rashes itch, such as those that often develop after an allergic reaction, but some rashes are painful or cause no symptoms. Drugs can causes rashes in several ways. Allergic drug rashes Most drug rashes result from an allergic reaction to the drug (see Allergies to Drugs). Usually the reaction is to a drug taken by mouth or injected. The drug does not have to be applied to the skin to cause a drug rash. When the immune system comes into contact with a drug, it can become sensitive to that drug (a process called sensitization). Sometimes a person becomes sensitized to a drug after only one exposure, and other times sensitization occurs only after many exposures. Once a person is sensitized to a drug, later exposure to that drug triggers an allergic reaction, such as a rash. Nonallergic drug rashes Sometimes a rash develops directly without involving an allergic reaction. For example, corticosteroids and lithium may cause a rash that looks like acne, and anticoagulants (blood thinners) may cause bruising when blood leaks under the skin. Certain drugs make the skin particu Continue reading >>
Dapagliflozin And Metformin (oral Route)
Precautions Drug information provided by: Micromedex It is very important that your doctor check your progress at regular visits, especially during the first few weeks that you take this medicine. Blood and urine tests may be needed to check for unwanted effects. It is very important to follow carefully any instructions from your doctor about: Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your doctor. Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems. Counseling—Other family members need to learn how to prevent side effects or help with side effects if they occur. Also, patients with diabetes may need special counseling about diabetes medicine dosing changes that might occur because of lifestyle changes, such as changes in exercise and diet. Furthermore, counseling on contraception and pregnancy may be needed because of the problems that can occur in patients with diabetes during pregnancy. Travel—Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times. In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification (ID) bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines. Under certain conditions, too much metformin can cause a Continue reading >>
Metformin, Oral Tablet
Metformin oral tablet is available as both a generic and brand-name drug. Brand names: Glucophage, Glucophage XR, Fortamet, and Glumetza. Metformin is also available as an oral solution but only in the brand-name drug Riomet. Metformin is used to treat high blood sugar levels caused by type 2 diabetes. FDA warning: Lactic acidosis warning This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects. Lactic acidosis is a rare but serious side effect of this drug. In this condition, lactic acid builds up in your blood. This is a medical emergency that requires treatment in the hospital. Lactic acidosis is fatal in about half of people who develop it. You should stop taking this drug and call your doctor right away or go to the emergency room if you have signs of lactic acidosis. Symptoms include tiredness, weakness, unusual muscle pain, trouble breathing, unusual sleepiness, stomach pains, nausea (or vomiting), dizziness (or lightheadedness), and slow or irregular heart rate. Alcohol use warning: You shouldn’t drink alcohol while taking this drug. Alcohol can affect your blood sugar levels unpredictably and increase your risk of lactic acidosis. Kidney problems warning: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug. Liver problems warning: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems. Metformin oral tablet is a prescription drug that’s available as the brand name drugs Glucophage, Glucophage XR, Fortamet, and Glumetza. Glucophage is an immediate-release tablet. All of the other brands are extended-r Continue reading >>
Metformin Hcl
Uses Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. How to use Metformin HCL Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually 1-3 times a day with meals. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects (such as upset stomach), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. If you are already taking another diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping/continuing the old drug and starting metformin. Check your blood sugar regularly a Continue reading >>
Glucophage
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. What is in this leaflet This leaflet answers some common questions about Glucophage. It does not contain all the available information. It does not take the place of talking to your doctor, diabetes educator or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Glucophage against the benefits expected for you. If you have any concerns about taking this medicine, talk to your doctor, pharmacist or diabetes educator. What Glucophage is used for Glucophage is used to control blood glucose (the amount of sugar in the blood) in people with diabetes mellitus. type 1 diabetes, also called insulin dependent diabetes or juvenile onset diabetes, when insulin alone is not enough to control blood glucose levels type 2 diabetes, also called non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes. It is especially useful in those who are overweight, when diet and exercise are not enough to lower high blood glucose levels (hyperglycaemia) Glucophage can be used alone, or in combination with other medicines for treating diabetes. Ask your doctor if you have any questions about why Glucophage has been prescribed for you. Glucophage is not recommended for use in children, except for those with insulin-resistant diabetes who are being treated in hospital. Glucophage is available only with a doctor's prescription. How Glucophage works Glucophage belongs to a group of medicines called biguanides. Glucophage lowers high blood glucose (hyperglycaemia) by helping your body make better use of the insulin produced by your pancreas. People with type 2 diabetes are unable to make enough insulin or their body does not respond properly to th Continue reading >>
