Obesity And Diabetes Risk

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Type 2 Diabetes Linked To Metabolic Health In Obesity

The risk for type 2 diabetes is increased in adults with obesity, whether they were metabolically healthy or unhealthy, and in those with normal weight who were metabolically unhealthy, according to findings published in Obesity Research & Clinical Practice. Dongsheng Hu, MD, of the department of epidemiology and health statistics at the College of Public Health, Zhengzhou University in China, and colleagues evaluated data from a cluster random sample of adults recruited from a rural Chinese population during July to August 2007 and July to August 2008 to determine whether risk for type 2 diabetes is associated with metabolically healthy obesity or metabolically unhealthy overweight or obesity. Participants were divided into groups based on their weight status and metabolic health status. Normal weight was defined as BMI of 18.5 kg/m2 to 23.9 kg/m2, and overweight or obesity as BMI of at least 24 kg/m2. The 6-year incidence of type 2 diabetes was 3.38 per 1,000 person-years for participants with baseline metabolically healthy normal weight, 5.53 for those with baseline metabolically healthy overweight or obesity, 9.89 for those with baseline metabolically unhealthy normal weight an Continue reading >>

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Popular Questions

  1. belle75

    I have PCOS + insulin resistance. Conceived DD1 after taking metformin. I am now pregnant (5wks) with my second. I've been taking metformin 850mg twice a day for 8 months now. Problem is, my ob wants me to cut down the dose to 850mg once a day and stop at 12 weeks. My insulin levels without metformin is all over the place and I am worried that my IR will be worse in pregnancy after eating all that bread I also had GD with my first pregnancy.
    With DD1, I took the full dose till 12 weeks then slowly reduced and stopped at 14 weeks. After reading all the stories about mc on stopping metformin, I am terrified! I have already used a few boxes of preg tests because I am paranoid something bad might happen I haven't had the courage to reduce the dose yet. Have my first ob appoint in 3 weeks. I don't know if i can bring this up with him. I know I am being a little paranoid. What would you do? HELP!!!
    ps: Sorry for rambling on like that. just had to get it all out in black and white. Thanks for listening!

  2. *LittleMissSummer*

    Im another who has PCOS plus insulin resistance and my levels evened out when i was pregnant. I had no issues at all, same with my SIL who also had an insulin resistance. Maybe you could ask for your levels to be monitored and talk further about staying on the metformin if needed. It is safe to have it during pregnancy so i dont know why your OB would want you to stop.

  3. Artechim

    Why do you need to come off the Metformin? If it is controlling your levels isn't that a good thing? I know they prefer injectable insulin during pregnancy in Aus, but Metformin has been used for GD as drug of choice in South Africa for over 20 years without ill effect.
    Are you eating a good low GI diet? I know it is hard, especially if you have been hit with morning sickness.

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