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Metformin Sri Lanka

Silagra 50 Dosage - Official Pharmacy #1

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Comparative In-vitro Evaluation Of Metformin Hcl And Paracetamol Tablets Commercially Available In Kandy District, Sri Lanka

Comparative In-vitro Evaluation Of Metformin Hcl And Paracetamol Tablets Commercially Available In Kandy District, Sri Lanka

Int J Pharm Pharm Sci, Vol 7, Issue 2, 520-524Original Article COMPARATIVE IN-VITRO EVALUATION OF METFORMIN HCl AND PARACETAMOL TABLETS COMMERCIALLY AVAILABLE IN KANDY DISTRICT, SRI LANKA T. W. HETTIARACHCHI1, D. B. M. WICKRAMARATNE1, S. H. T SUDESHIKA1, DAKSHILA NIYANGODA1, M. H. F SAKEENA1, H. M. D. R. HERATH*1 1Department of Pharmacy, Faculty of Allied Health Sciences, University of Peradeniya, Peradeniya, Sri Lanka. Received: 14 Nov 2014 Revised and Accepted: 08 Dec 2014 Objective: Availability of numerous brands of tablets with price variations compared to their generic drugs in the current drug market places health practitioners, pharmacists and patients in a dilemma of generic substitution. In such background, this study was aimed to compare the in-vitro efficacy of some of the low priced generic tablets with their brands commonly available in Sri Lanka. Methods: A survey of the prices of commonly used tablets and capsules available at pharmacies in Kandy area in Sri Lanka was carried out. Based on the results of the survey, frequently used two tablets; Metformin HCl (one locally manufactured generic (M1) and 3 brands M2-M4) and Paracetamol (one locally manufactured generic (P1) and two brands P2-P3) were selected for the study. All the products were examined visually for their organoleptic properties and tested for uniformity of weight, disintegration time, assay value, dissolution rate, hardness or crushing strength and friability. Pertinent official guidelines were followed throughout all the tests. Results: The results of aesthetic assessment showed no sign of defects and all the tested tablets complied with the official standards for the above parameters. Despite some minor differences in tablet hardness and disintegration time profiles, other in-vitro char Continue reading >>

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Consenting patients will be randomized into two arms using a random number table. Randomization will be done around post operative day three when the patient has achieved satisfactory glycaemic control with insulin during the intra-operative and post-operative period. Arm one will receive insulin and metformin, and arm two will receive metformin and a sulphonyluria (gliclazide). The Initial dose of metformin will be 500mg three times daily for both arms. Depending on the patient requirement and tolerability the dose will be titrated slowly to a maximum dose of 2g per day. Arm one will receive pre mixed (Mixtard) insulin twice a day with or without lunch time soluble insulin depending on blood glucose control. Arm two will receive gliclazide with a starting dose based on previous insulin requirement (total daily dose between 40mg 160mg). The dose will be titrated depending on blood glucose control to a maximum of 320mg per day. While hospitalized, the target pre meal capillary blood glucose (CBG) will be below 140 mg/dl and random blood glucose (RBG) will be below 180 mg/dl (American Diabetic Association cutoffs). During the follow up period the target fasting blood glucose (FBG) will be below 100mg/dl and post prandial blood glucose (PPBG) will be below 140mg/dl. All patients will be followed up at the diabetic clinic, NHSL. All patients will be educated on life style modification including diet control, regular exercise , need of cessation of smoking etc by medical officers and diabetic educating nursing officers during hospital stay and at each clinic visit Patients with type 2 diabetes admitted to Cardio-thoracic units of the National Hospital of Sri Lanka for coronary artery bypass grafting (CABG) Daily insulin requirement of <1IU/kg/day to achieve satisfactory gly Continue reading >>

Comparative In-vitro Evaluation Of Metformin Hcl And Paracetamol Tablets Commercially Available In Kandy District, Sri Lanka | Hettiarachchi | International Journal Of Pharmacy And Pharmaceutical Sciences

Comparative In-vitro Evaluation Of Metformin Hcl And Paracetamol Tablets Commercially Available In Kandy District, Sri Lanka | Hettiarachchi | International Journal Of Pharmacy And Pharmaceutical Sciences

COMPARATIVE IN-VITRO EVALUATION OF METFORMIN HCl AND PARACETAMOL TABLETS COMMERCIALLY AVAILABLE IN KANDY DISTRICT, SRI LANKA T. W. Hettiarachchi, D. B. M. Wickramaratne, S. H. T Sudeshika, Dakshila Niyangoda, M. H. F Sakeena, H. M. D. R. Herath Objective: Availability of numerous brands of tablets with price variations compared to their generic drugs in the current drug market places health practitioners, pharmacists and patients in a dilemma of generic substitution. In such background, this study was aimed to compare the in-vitro efficacy of some of the low priced generic tablets with their brands commonly available in Sri Lanka. Methods: A survey of the prices of commonly used tablets and capsules available at pharmacies in Kandy area in Sri Lanka was carried out. Based on the results of the survey, frequently used two tablets; Metformin HCl (one locally manufactured generic (M1) and 3 brands M2-M4) and Paracetamol (one locally manufactured generic (P1) and two brands P2-P3) were selected for the study. All the products were examined visually for their organoleptic properties and tested for uniformity of weight, disintegration time, assay value, dissolution rate, hardness or crushing strength and friability. Pertinent official guidelines were followed throughout all the tests. Results: The results of aesthetic assessment showed no sign of defects and all the tested tablets complied with the official standards for the above parameters. Despite some minor differences in tablet hardness and disintegration time profiles, other in-vitro characteristics of the tested brands; Paracetamol and Metformin HCl and their locally manufactured generics appears to be similar and not significantly different from each other. Conclusion: According to in-vitro official quality control t Continue reading >>

Metformin Safe | Daily News

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Why Isn’t Metformin Prescribed More?

Why Isn’t Metformin Prescribed More?

Since its debut in the United States in 1995, metformin has become the most popular oral drug for Type 2 diabetes in the country — and the rest of the world. Current guidelines by the American Diabetes Association state that unless there are special risks in a particular person, metformin should be the first drug prescribed to people with Type 2 diabetes. Yet perhaps due in part to its popularity, metformin isn’t free of controversy. As we’ve discussed previously here at Diabetes Flashpoints, there are concerns about prescribing metformin in people with kidney disease, and some doctors even question whether metformin deserves its status as the universally recommended first-line drug for Type 2 diabetes. In addition, there’s debate about whether metformin should be taken by more people with prediabetes. A recent study sought to explore the reasons why metformin isn’t prescribed as widely as clinical guidelines suggest it should be. Published last month in the journal Therapeutic Advances in Chronic Disease, the study notes that only roughly 65% of people with newly diagnosed Type 2 diabetes are prescribed metformin — and that over time, this number drops to just 25% of people with the condition. As noted in a Pharmacy Times article on the study, researchers from the University of Colorado put together focus groups of relevant people — doctors, pharmacists, and other medical personnel — to ask about their perceptions regarding metformin. Based on these focus groups, the researchers found that three main factors affected how doctors prescribed metformin: concerns about when to start the drug, concerns about the drug’s known risks, and whether procedures were in place to notice and deal with any adverse reactions caused by the drug. Based on the focus grou Continue reading >>

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The study will be conducted at the department of Pharmacology, Faculty of medicine, University of Peradeniya, Sri Lanka.Consenting patients meeting inclusion/exclusion criteria will be randomized into four arms. Arm 1 - Two mg of cyproterone acetate and 35 microg of ethinyl estradiol pill dailyplacebo pill equal to Metformin SR 500mg pill daily placebo pill equal to desogestrel 0.15mg/ ethinyl estradiol(20 microg) pill daily Arm 2 - Desogestrel 0.15mg/ ethinyl estradiol(20 microg) dailyplacebo pill equal to metformin SR 500mg pill daily placebo pill equal to 2 mg of cyproterone acetate and 35 microg of ethinyl estradiol pill daily Arm 3 - Metformin (SR) 500mg daily2 mg of cyproterone acetate and 35 microg of ethinyl estradiol daily placebo pill equal to desogestrel 0.15mg/ ethinyl estradiol(20 microg) pill daily Arm 4 - Metformin(SR) 500mg daily desogestrel 0.15mg/ ethinyl estradiol(20 microg) dailyplacebo pill equal to 2 mg of cyproterone acetate and 35 microg of ethinyl estradiol pill daily These drugs will be given for duration of one year for all four arms. Age more than 18 years and less than 40 years Diagnosis of PCOS according to the 2003 Rotterdam Consensus conference criteria One or more of the following dermatological manifestations of hyperandrogenism: hirsutism, androgenetic alopecia, acne Women wishing to conceive during the next 12 months Personal or family history of breast carcinoma Women with contraindications to use oral contraceptives (WHO criteria) and metformin History of metformin use within the previous 8 weeks Hirsuitism as measured by1. Objective hair measures Patients will be instructed not to remove hair by any means at least 5 days before the measurements. They will be asked to keep a note on date of hair removal before performing the hair r Continue reading >>

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An Ethnographic Study Of Diabetes Health Beliefs And Practices In Sri Lankan Adults

An Ethnographic Study Of Diabetes Health Beliefs And Practices In Sri Lankan Adults

beliefs and practices in Sri Lankan adults A.A.T.D. Amarasekara1,2 RN, W. Fongkaew3RN,PhD, S. Turale4RN,DEd,FACNA,FACMHN, S.W. Wimalasekara5MBBS,PhD& 1PhD Candidate, 3Professor and Chair of PhD International program, 4Professor of International Nursing, Faculty of Nursing, Chiang Mai University, 6Associate Professor, Department of Public Health Nursing, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand 2Lecturer, Department of Allied Health Sciences, 5Professor of Physiology, Department of Physiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka AMARASEKARA A.A.T.D., FONGKAEW W., TURALE S., WIMALASEKARA S.W. & CHANPRASIT C. (2014) An ethnographic study of diabetes health beliefs and practices in Sri Lankan adults. International Background: Globally, type 2 diabetes is increasingly prevalent; however, unique cultural contexts in each country might affect these diabetes control behaviours. Diabetes is a serious health issue in Sri Lanka and little is known about the impact of sociocultural context on diabetes health behaviours. Aim: This rst-time qualitative Sri Lankan study explored the health beliefs and practices of adults with diabetes to enhance current nursing care and medical treatment. Methods: An ethnographic approach was used to collect data through participant observations, in-depth interviews with 14 key informants in their homes and eld notes. Data were analysed by thematic analysis. Results: Findings revealed unique, informative insights into sociocultural worlds of the participants from three Sinhalese, Tamils and Moor ethnic groups. Findings are described under ve themes: gaining religious support, changing food habits is a struggle, exercising is challenging, Western medicine causes long-term consequen Continue reading >>

Heres Why Doctors Have Stopped Prescribing Metformin

Heres Why Doctors Have Stopped Prescribing Metformin

Heres Why Doctors Have Stopped Prescribing Metformin We are rapidly moving toward the day when individuals determined to have Type II Diabetes can kiss farewell to their costly pills and irritating needles and test strips. This is because of an achievement from a Sri Lankan scientist, a master in endocrinology with 23 years involvement, that will change all that we considered how to treat Type II Diabetes No more needles! Would you attempt a Flavorful Dishor even a Marvel Smoothie that could tackle the issue of diabetes normally? Mr. Michel Dempsey, in an overcome (and fortunate) endeavor to spare his better half from diabetes found a Sri Lankan tribe that has 0 instances of diabetes or pre diabetes. Despite seemingly insurmountable opposition he was capable, with the assistance of a Sri Lankan specialist from the college of Peradeniya, to build up a characteristic treatment to invert diabetes utilizing precisely the same the tribe has been expending for a considerable length of time. He said that he just couldnt see the mother of his 3 youngsters unfit to push off the shackles of diabetes. He needed to locate a superior future for her. Presently, quite a while of research, study and analyses later, Chaminda, the Sri Lankan scientist, has found a shockingly straightforward approach to stop diabetes and even switch it, giving you back the life you had some time recently. The technique includes getting rid of the sustenances that are aggravating the issue, and supplanting them with fixings and superfood that has specialists bewildered. This new technique was met with unforgiving feedback from the medicinal group and pharmaceutical organizations, yet he was never condemned by the individuals who really attempt it; a large portion of them encountered achievement in only fo Continue reading >>

Use Of Complementary And Alternative Medicines (cams) Among Type 2 Diabetes Patients In Sri Lanka: A Cross Sectional Survey

Use Of Complementary And Alternative Medicines (cams) Among Type 2 Diabetes Patients In Sri Lanka: A Cross Sectional Survey

Use of Complementary and Alternative Medicines (CAMs) among type 2 diabetes patients in Sri Lanka: a cross sectional survey We are experimenting with display styles that make it easier to read articles in PMC. The ePub format uses eBook readers, which have several "ease of reading" features already built in. The ePub format is best viewed in the iBooks reader. You may notice problems with the display of certain parts of an article in other eReaders. Generating an ePub file may take a long time, please be patient. BMC Complementary and Alternative Medicine Use of Complementary and Alternative Medicines (CAMs) among type 2 diabetes patients in Sri Lanka: a cross sectional survey Arjuna B Medagama, Ruwanthi Bandara, [...], and Thamudika Pushpakumari The incidence of chronic illnesses has increased worldwide. Diabetes is one such illness and 80% of the diabetic population lives in the developing world. There is a rapidly growing trend towards the use of Complementary and Alternative Medical practices in Diabetes. Sri Lanka is a developing Asian nation with a rich culture of Ayurvedic and native medical culture. The objective of this study was to find the prevalence of use of CAMs in a diabetic population attending a large multiethnic diabetes facility in a University unit and to assess whether there is an increase in the incidence of hypoglycaemic episodes among users of CAMs. A cross sectional study was performed at Teaching Hospital Peradeniya between April and August 2012. Following verbal consent, 254 type 2 adult diabetic patients attending the diabetes facility were interviewed regarding the use of CAM and hypoglycaemia using an interviewer-administered questionnaire. Of the 252 valid results, 192 patients (76%) admitted to the use of a CAM to reduce blood glucose. B Continue reading >>

Here’s Why Doctors Have Stopped Prescribing Metformin

Here’s Why Doctors Have Stopped Prescribing Metformin

We are quickly approaching the day when people diagnosed with Type II Diabetes can kiss goodbye to their expensive pills and annoying needles and test strips. This is thanks to a breakthrough from a Sri Lankan researcher, a specialist in endocrinology with 23 years’ experience, that is going to change everything we thought we knew about how to treat Type II Diabetes... No more needles! Would you be willing to try a "Delicious Dish"or even a "Miracle Smoothie" that could solve the problem of diabetes naturally? Mr. Michel Dempsey, in a brave (and lucky) attempt to save his wife from diabetes discovered a Sri Lankan tribe that has 0 cases of diabetes or pre diabetes. Against all odds he was able, with the help of a Sri Lankan researcher from the university of Peradeniya, to develop a natural treatment to reverse diabetes using the exact same ingredients the tribe has been consuming for decades. He said that he just couldn't see the mother of his 3 children unable to cast off the shackles of diabetes. He wanted to find a better future for her. Now, several years of research, study and experiments later, Chaminda, the Sri Lankan researcher, has discovered a surprisingly simple way to stop diabetes and even reverse it, giving you back the life you had before. The method involves doing away with the foods that are making the problem worse, and replacing them with ingredients and superfood that has doctors baffled. This new method was met with harsh criticism from the medical community and pharmaceutical companies, but he was never criticised by those who actually try it; most of them experienced success in just a few weeks. Michel says that this method has proven results, and these results can speak for themselves. By now you’re probably wondering why you’ve never heard Continue reading >>

Metformin Therapy For Diabetes Mellitus In Prader-willi Syndrome

Metformin Therapy For Diabetes Mellitus In Prader-willi Syndrome

Metformin therapy for diabetes mellitus in Prader-Willi syndrome Sri Lanka Journal of Child Health, 2007; 36: 24-26 Key words: Metformin therapy, diabetes mellitus, Prader-Willi syndrome How to Cite: de Alwis, A. et al., (2008). Metformin therapy for diabetes mellitus in Prader-Willi syndrome. Sri Lanka Journal of Child Health. 36(1), pp.2426. DOI: de Alwis, A. et al., (2008). Metformin therapy for diabetes mellitus in Prader-Willi syndrome. Sri Lanka Journal of Child Health. 36(1), pp.2426. DOI: de Alwis A, Senarathne A, Morawakkorala R, Weerasinghe B, Liyanage S. Metformin therapy for diabetes mellitus in Prader-Willi syndrome. Sri Lanka Journal of Child Health. 2008;36(1):246. DOI: de Alwis, A., Senarathne, A., Morawakkorala, R., Weerasinghe, B., & Liyanage, S. (2008). Metformin therapy for diabetes mellitus in Prader-Willi syndrome. Sri Lanka Journal of Child Health, 36(1), 2426. DOI: de Alwis, ACD, AMRD Senarathne, RN Morawakkorala, B Weerasinghe, and S Liyanage. 2008. Metformin therapy for diabetes mellitus in Prader-Willi syndrome 36, no. 1: 2426. DOI: Continue reading >>

Giving Up Metformin For Coconut Oil

Giving Up Metformin For Coconut Oil

There ya go! I think Genetics plays a huge role in everything that is our down-falls in life. What works for you won't work for me but might for my neighbor. It is a crap shoot. I say enjoy life, everything in moderation, do what makes you feel great! If that means having steak for dinner so be it. Personally, food is not my main thing, I like to do fun stuff, food is what I do to keep going, nothing more, nothing less. I hate that I have to talk about it and think about it daily! But, it is what it is. Both of my parents followed their doctor's advice to the letter, most of their lives. They never ate fat, we always had margerine and skim milk in the house. They rarely ate red meal and of course they never ate sugar. But they ate tons of fruit, whole grains, veggies and all the good things they tell you to eat. They were both fairly thin and walked every day. My dad had a heart attack in his 70's and my mom ended up with blood clots and had to have a pacemaker put in and then last year she had another one. She now has Congestive Heart Disease. So without eating fat, they both developed heart disease. So there are no guarantees in life that avoiding fat is helpful. Both of my parents followed their doctor's advice to the letter, most of their lives. They never ate fat, we always had margerine and skim milk in the house. They rarely ate red meal and of course they never ate sugar. But they ate tons of fruit, whole grains, veggies and all the good things they tell you to eat. They were both fairly thin and walked every day. My dad had a heart attack in his 70's and my mom ended up with blood clots and had to have a pacemaker put in and then last year she had another one. She now has Congestive Heart Disease. So without eating fat, they both developed heart disease. So th Continue reading >>

Metformin - Brand Name List From Drugs.com

Metformin - Brand Name List From Drugs.com

Important: The information below refers to medicines available in the United States that contain metformin. Search the entire Drugs.com site for metformin Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region. The Drugs.com website is intended primarily for audiences in the United States and its territories. Indications, uses and warnings on Drugs.com patient information leaflets are derived from FDA product labels and may differ in countries outside the USA. Every effort has been made to ensure that the information provided on this page is accurate, up-to-date and complete, but no guarantee is made to that effect. Drugs.com does not endorse drugs, diagnose patients or recommend specific therapies. The information on this page is not a substitute for the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Always consult your doctor or healthcare specialist for medical advice. ATC code(s): A10BA02, A10BD13, A10BD18, A10BD16, A10BD10, A10BD02, A10BD03, A10BD14, A10BD15, A10BD08, A10BD05, A10BD11, A10BD17, A10BD20, A10BD07 Continue reading >>

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