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Metformin Recall Australia

Metformin In Gestational Diabetes: The Offspring Follow-up (mig Tofu)

Metformin In Gestational Diabetes: The Offspring Follow-up (mig Tofu)

Metformin in Gestational Diabetes: The Offspring Follow-Up (MiG TOFU) 1Department of Obstetrics, National Womens Health, Auckland, New Zealand 2Centre for Child Health Research, Auckland University of Technology, Auckland, New Zealand 3Department of Biological Sciences, University of Auckland, Auckland, New Zealand 4Department of Pediatrics, National Womens Health, Auckland, New Zealand 5Department of Psychological Medicine, University of Auckland, Auckland, New Zealand 6Department of Obstetrics, Women and Childrens Hospital, University of Adelaide, Adelaide, Australia Corresponding author: Janet A. Rowan, [email protected] . Received 2011 Apr 7; Accepted 2011 May 26. Copyright 2011 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See for details. See editorial " Metformin Therapy During Pregnancy " onpage2329. This article has been cited by other articles in PMC. In women with gestational diabetes mellitus, who were randomized to metformin or insulin treatment, pregnancy outcomes were similar (Metformin in Gestational diabetes [MiG] trial). Metformin crosses the placenta, so it is important to assess potential effects on growth of the children. In Auckland, New Zealand, and Adelaide, Australia, women who had participated in the MiG trial were reviewed when their children were 2 years old. Body composition was measured in 154 and 164 children whose mothers had been randomized to metformin and insulin, respectively. Children were assessed with anthropometry, bioimpedance, and dual energy X-ray absorptiometry (DEXA), using standard methods. The children were similar for baseline maternal characteristics and pregnancy outcomes. In the metfor Continue reading >>

Diabetes Recalls And Alerts | The Diabetic News - Official Site

Diabetes Recalls And Alerts | The Diabetic News - Official Site

Recall King Arthur Flour Recalled Nationwide Due to Salmonella King Arthur Flour Company is recalling flour due to salmonella, an organism which can cause serious and sometimes fatal infections Nationwide Frozen Green Bean Recall, Multiple Brands Including Blends National Frozen Foods Corporation (NFFC) is voluntarily recalling a limited quantity of Not-Ready-To Eat Individually Quick Frozen (IQF) green beans and IQF mixed vegetables... Pharmacist Choice Alcohol Pads Recalled Due to Sterility and Quality Issues Pharmacist Choice Alcohol Prep Pads have been recalled due to the lack of sterility assurance and other quality issues which could result in adverse events such as infections. Riomet Metformin Lots Recalled Due to Contamination Riomet Metformin, used to treat type 2 diabetes in adults and children over 10, has been recalled due to contamination. See full details and lot information. Vegetable Recall Hits United States and Canada Due to Listeria Dozens of vegetable products distributed in the United States and Canada are recalled because they may be contaminated with listeria monocytogenes. See the full listing of affected products. Worldwide Medtronic Recall of Diabetes Infusion Sets due to Hypoglycemia Risk Medtronic has started a worldwide recall of specific lots of infusion sets used with all models of Medtronic insulin pumps for diabetes due to hypoglycemia risk. Fresh Vegetables Recalled in Multiple States and Stores, Including Walmart Country Fresh Orlando is recalling products in several states sold as store brands that include Walmart and Publix due to risk of Listeria monocytogenes. Nationwide Liquid Supplement Recall by Multiple Brands Due to Contamination Voluntary Nationwide Recall of all Liquid Products Manufactured by Pharmatech LLC and Distributed Continue reading >>

Safety Alert: Saxagliptin And Metformin--bristol-myers Squibb Recalls Several Lots Of Kombiglyze Xr Tablets, Doctor Samples | Mediguard

Safety Alert: Saxagliptin And Metformin--bristol-myers Squibb Recalls Several Lots Of Kombiglyze Xr Tablets, Doctor Samples | Mediguard

This recall for Kombiglyze XR Tablets, 5 mg/500 mg and 2.5 mg/1000 mg Samples was issued at a warehouse and doctors office level only. The FDA and the manufacturer have determined that any recalled product that may have been given to patients does not pose a significant health risk. If you take Kombiglyze XR 5 mg/500 mg or 2.5 mg/1000 mg samples from your doctor, check your supply and see if they are labeled with one of the recalled lot numbers. Take any samples with the recalled lot numbers back to your doctor and confirm that you are taking the correct strength. Please speak to your doctor if you have any concerns about this alert or your medicine. Bristol-Myers Squibb Recalls Several Lots of Kombiglyze XR Tablets, Doctor Samples Bristol-Myers Squibb has recalled several lots of Kombiglyze XR (saxagliptin and metformin HCl extended-release) Tablets, 5 mg/500 mg and 2.5 mg/1000 mg blister pack doctor samples. The following lot numbers have been recalled because the labels on the outside boxes may be labeled with the wrong drug strength: Kombiglyze XR 2.5 mg/1000 mg Sample Not For Sale 6 Tablets per Carton: 1J6024PA, 1J6025PA, 1K6049PA, and 1L9015WA Kombiglyze XR 5 mg/500 mg Sample Not For Sale 7 Tablets per Carton: 1J6024PA , 1J6025PA, 1K6049PA, and 1L9015WA Kombiglyze XR contains the active ingredient saxagliptin and metformin and is commonly used in the treatment of diabetes. This recall alert only applies to the select lots of Kombiglyze XR Tablets, 5 mg/500 mg and 2.5 mg/1000 mg Samples. No other saxagliptin and metformin products were involved in this recall. To view the FDA notice about this recall, please visit: www.accessdata.fda.gov/scripts/enforcement/enforce_rpt-Event-Detail.cfm?action=detail&id=62898&w=10312012&lang=eng Monitor the medical treatment of you Continue reading >>

Apotex Recalls Metformin Batch In Australia

Apotex Recalls Metformin Batch In Australia

Apotex recalls metformin batch in Australia Apotex has recalled a batch its diabetes drug APO-Metformin XR in Australia after a pill was plastic from a cable or zip tie was found embedded in a pill. The Therapeutic Goods Administration (TGA) posted details on its website on January 19, explaining that Apotex initiated the recall as a precautionary measure over concerns the pills pose a threat to patients. The TGA wrote, There has been one report of a small piece of white plastic likely from a cable/zip tie being embedded in a tablet from this batch. The plastic may or may not be visible, as it could be completely embedded in the tablet. If a small piece of plastic is swallowed with the tablet there is a small risk of choking or perforation of the gastrointestinal tract. The plastic is not toxic or carcinogenic. Copyright - Unless otherwise stated all contents of this web site are 2018 - William Reed Business Media Ltd - All Rights Reserved - Full details for the use of materials on this site can be found in the Terms & Conditions Continue reading >>

Plastic Fragment Recall

Plastic Fragment Recall

Apotex and the TGA are advising of a recall of a batch of metformin Apotex, in consultation with the TGA, is warning consumers and health professionals that it is recalling a batch of APO-Metformin XR 1000 mg tablets (batch number E16539). There has been a report of a small piece of white plastic likely from a cable or zip tie embedded in a tablet from this batch. The plastic may or may not be visible, as it could be completely embedded in the tablet, Apotex and the TGA say. If a small piece of plastic is swallowed with the tablet there is a small risk of choking or perforation of the gastrointestinal tract. The plastic is not toxic or carcinogenic. They are advising patients and their carers to check the batch number on any packets of AJP-Metformin XR 1000mg to see whether it is from the affected batch, and to return any product from the affected batch to a pharmacy for refund or replacement. Apotex says it is writing to pharmacists to provide further information about the issue, including details of the recall procedure. It has asked them to inspect their stock and quarantine any from batch number E16539. If pharmacists or any other health professionals notice or receive reports of any suspected contamination of other batches of APO-Metformin XR 1000 mg tablets, please report it to the TGA, it says. For further information contact Apotex on 1800 276 839. Continue reading >>

Side Effects Of Metformin May Cause Problems With Thinking: Study

Side Effects Of Metformin May Cause Problems With Thinking: Study

The findings of a new study raises potential concerns about the side effects of meformin, suggesting that the popular diabetes drug may impair brain functions and cause users to experience problems thinking. Metformin is a widely used medication for treatment of type 2 diabetes, which is also known under the brand names Glumetza, Riomet, Fortamet and Glucophage. It is also part of several popular combination therapies, including the blockbuster medication Janumet, which combines metformin with the top selling diabetes drug Januvia. In a report published by the journal Diabetes Care, researchers compiled data from several different studies, including the Primary Research in Memory (PRIME) study; Australian Imaging, Biomarkers and Lifestyle (AIBL) study and data from the Barwon region of southeastern Australia. Researchers found that participants with diabetes performed worse on cognitive performance than those who did not have diabetes, with individuals taking a metformin drug performing significantly worse. More than 1,300 patients were evaluated who had Alzheimer’s disease, mildly impaired brain function and no cognitive impairments; along with a subset group which also had type 2 diabetes or impaired glucose intolerance. Patients who suffered a stroke or had neurodegenerative diseases other than Alzheimer’s were not included in the study. Patients with type 2 diabetes performed poorly on cognitive impairment tests and those who took metformin performed even worse. Researchers found metformin was associated with a vitamin B12 deficiency, which in turn resulted in impaired cognitive performance. Patients with vitamin B12 levels less than 250 pmol/L had the worst cognitive performance. Conversely, patients with type 2 diabetes taking metformin, but who also took calc Continue reading >>

Apo-metformin Xr 1000 Mg Tablets

Apo-metformin Xr 1000 Mg Tablets

Australian Government Department of Health Recall - risk of injury due to potential contamination with plastic fragment Consumers and health professionals are advised that Apotex, in consultation with the TGA, is recalling one batch of APO-Metformin XR 1000 mg tablets (batch number E16539). APO-Metformin XR 1000 mg tablets are used to treat type 2 diabetes in adults and children over 10 years of age. There has been one report of a small piece of white plastic (likely from a cable/zip tie) being embedded in a tablet from this batch. The plastic may or may not be visible, as it could be completely embedded in the tablet. If a small piece of plastic is swallowed with the tablet there is a small risk of choking or perforation of the gastrointestinal tract. The plastic is not toxic or carcinogenic. No other batches are affected by this recall. If you or someone you provide care for takes APO-Metformin XR 1000 mg tablets, check the batch number on the package to see if it is from the affected batch (batch number E16539). If you have a product from the affected batch, return it to a pharmacy for a refund or replacement. If you have any other questions or concerns about this issue, talk to your health professional. If you treat patients who take APO-Metformin XR 1000 mg tablets, please be aware of this issue. Apotex is writing to pharmacists to provide further information about this issue, including details of the recall procedure. Please inspect your stock and quarantine any products from the affected batch (batch number E16539). Patients returning unused or partially used packs should be provided a full refund or replacement. If pharmacists or any other health professionals notice or receive reports of any suspected contamination of other batches of APO-Metformin XR 1000 mg Continue reading >>

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Differing Brands Of Generic Metformin Behave Differently

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Dr. Bernstein has been preaching about this on his web telecasts for years, but it bears repeating: If you are having problems with generic metformin or not seeing it make much impact on your blood sugar, change brands before you assume it isn't working or that you can't tolerate it. I just had this message brought home to me when my pharmacy (Walgreens) filled my prescription for metformin ER with tablets from SunPharma instead of the ones from Teva they'd given me for years. The pills were about half the size of the ones I'd been getting, which suggested they contained less of a matrix substance to slow the release of the metformin. And sure enough, when I took the same dose I had been taking with no problems with the Teva brand metformin, I felt exhausted and semi-poisoned. It felt just like when I had taken an overdose of metformin some years ago, when my family doctor prescribed an overdose after confusing the dosage instructions for regular metformin--which can be taken in larger doses--with those of metformin ER. Not only that, but my fasting blood sugars went up. Clearly the SunPharma metformin ER was not behaving like a true extended release should and releasing slowly through a 24 hour period but was hitting my blood stream all at once and then was done. A quick visit to Google revealed that Sun Pharmaceuticals is an Indian company and that in the past the FDA has forced them to recall batches for quality issues. When it was time to refill my prescription, I called my pharmacy and spoke with the pharmacist who shrugged off my concerns and told me I'd have to speak to the pharmacy manager (not available that day.) So I got on the phone and called other local pharmacies and asked them what brand they were dispensing. Two of them still carry the Teva brand, so I Continue reading >>

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Metformin And Impaired Thinking

Metformin And Impaired Thinking

According to new research from Australia, the oral diabetes medicine metformin is linked to impaired brain function, but supplementation with vitamin B12 may reduce some of the cognitive effects. Metformin is the most widely used diabetes drug in the world, with over 61 million prescriptions for the medicine filled in the United States alone in 2012. To evaluate the effects of the drug on cognitive impairment in people with diabetes, researchers recruited 1,354 people from various locations in Australia. The researchers included people with Alzheimer disease and mild cognitive impairment, as well as those who were cognitively normal, but they did not include people with stroke or neurological conditions other than Alzheimer. The participants had an average age of 73.8 and almost 60% were female The study used an evaluation known as the mini-mental state exam to determine cognitive performance. According to the results, slightly more than half of the participants were not cognitively impaired, while 21.8% were minimally impaired, 17.7% were mildly impaired, and 10.1% were most impaired. In their analysis, the researchers found that people with Type 2 diabetes had worse cognitive performance than those without Type 2 and that, among those with diabetes, people taking metformin had worse cognitive performance than those not taking the medicine. Cognitive function scores were also found to be lower among those with vitamin B12 levels of less than 250 pmol/l. Because metformin is known to be associated with B12 deficiency, the investigators suggested that “any effect metformin has on cognitive performance may be at least partially mediated by altering serum vitamin B12 levels.” Limitations of the study include an insufficient amount of information about the duration of t Continue reading >>

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Long-term Metformin Treatment Found To Reduce Risk Of Heart Disease In Adults With Type 1 Diabetes

Long-term Metformin Treatment Found To Reduce Risk Of Heart Disease In Adults With Type 1 Diabetes

Long-Term Metformin Treatment Found to Reduce Risk of Heart Disease in Adults with Type 1 Diabetes According to results of international REMOVAL trial of more than 400 adults with type 1 diabetes SAN DIEGO, June 11, 2017 /PRNewswire/ --Metformin may be an effective long-term strategy worthy of adding to an individual's diabetes care plan in order to reduce the risk of heart disease in adults with type 1 diabetes, according to the findings of the study titled, "Results of the JDRF Reducing with Metformin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)," presented today at the American Diabetes Association's 77th Scientific Sessions at the San Diego Convention Center. Metformin is an inexpensive medication considered first-line therapy for treatment of glucose control in individuals with type 2 diabetes. It is also widely used to improve cardiovascular risk in adults with type 2 diabetes. This study examined if similar benefits could be expected for people with type 1 diabetes. Metformin may be prescribed for people with type 1 diabetes who are also overweight, to help control blood sugar and weight, allowing a lower daily insulin dose. This multi-center, international clinical trial enrolled patients at 23 centers across the United Kingdom, Australia, Canada, Denmark and the Netherlands. Researchers investigated if three years of treatment with metformin reduces heart disease in middle-aged adults with type 1 diabetes who are at increased risk for cardiovascular disease (CVD). Ultrasound was used to measure thickening (atherosclerosis) in the carotid arterieslarge blood vessels in the neck as a surrogate marker of heart disease. Atherosclerosis is a form of hardening of the arteries that is the leading cause of heart attacks, strokes and peripheral vascular diseas Continue reading >>

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