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Herbal Alternatives To Metformin

Metformin (Glucophage, Glumetza, Fortamet) is typically prescribed to counteract the effects of insulin resistance -- the body's sluggish response to the blood-sugar-lowering hormone insulin. Insulin resistance can lead to high blood sugars and may eventually progress to prediabetes or type 2 diabetes (T2DM). Metformin improves insulin sensitivity of the body tissues and reduces liver glucose production, both of which help lower blood sugar levels. The American Diabetes Association recommends metformin as a first-choice medicine to treat T2DM. It is also sometimes used in combination with exercise and weight loss in people with prediabetes. Some evidence suggests that a few herbs might mimic some of the effects of metformin. However, no herb is a proven alternative to metformin. Video of the Day Goat’s rue, or Galega officinalis, is an age-old remedy. In times past, it was used for assorted ailments, including diabetes. Metformin is a man-made chemical that's closely related to a substance found in goat’s rue. Animal studies from the 1970s and 1980s established that substances in goat's rue have blood-sugar-lowering effects. Some of these chemicals can be toxic, however, so human studies are lacking. A recent animal study was published in April 2008 in the "British Journal of Pharmacology." Researchers found that mice fed galegine -- a chemical found in goat's rue -- ate less, lost weight and had reduced blood sugar levels, compared to mice that weren't fed the chemical. Goat's rue is not approved for diabetes treatment by the U.S. Food and Drug Administration or Germany's Commission E, a scientific advisory board that reviews and approves herbal medicines. Commission E noted significant health risks with goat's rue and the availability of more effective diabetes tr Continue reading >>

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Metformin Drug Interactions

A total of 702 drugs (4976 brand and generic names) are known to interact with metformin. Show all medications in the database that may interact with metformin. Check for interactions with metformin Type in a drug name and select a drug from the list. Common medications checked in combination with metformin metformin alcohol/food Interactions There is 1 alcohol/food interaction with metformin FDA-Approved Weight-Loss Drug - Once-Daily Treatment Need Obesity Help? Learn About an Option That May Help You Reach Your Goal. Prescription treatment website metformin disease Interactions There are 4 disease interactions with metformin which include: The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown No information available. Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, Continue reading >>

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Terry White Chemists Metformin 500/850/1000

PDFLARGE FONT PDF Contains the active ingredient metformin (met-FOR-min) hydrochloride Consumer Medicine Information For a copy of a large print leaflet, Ph: 1800 195 055 What is in this leaflet Read this leaflet carefully before taking your medicine. This leaflet answers some common questions about metformin It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist or diabetes educator. The information in this leaflet was last updated on the date listed on the last page. More recent information on this medicine may be available. Ask your doctor or pharmacist: if there is anything you do not understand in this leaflet, if you are worried about taking your medicine, or to obtain the most up-to-date information. You can also download the most up-to-date leaflet from www.apotex.com.au. All medicines have risks and benefits. Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. Pharmaceutical companies cannot give you medical advice or an individual diagnosis. Keep this leaflet with your medicine. You may want to read it again. What this medicine is used for The name of your medicine is Terry White Chemists Metformin 500, 850 or 1000 tablets. It contains the active ingredient metformin (as metformin hydrochloride). It is used to treat type 2 diabetes (also called non-insulin dependent diabetes mellitus or maturity onset diabetes) in adults and children over 10 years of age. It is especially useful in those who are overweight, when diet and exercise are not enough to lower high blood glucose levels (hyperglycaemia). For adult patients, metformin can be used alone, or in combination with other oral diabetic medicines or in combination with insulin in insul Continue reading >>

Fight Aging!

Fight Aging!

This lengthy post walks through the process of setting up and running a self-experiment - a trial of one - of candidate senolytic drugs capable of removing some portion of the senescent cells that accumulate with age to cause aging and age-related disease. Metrics are assessed beforehand and afterwards in order to shed some light on whether or not it worked, in the sense of producing some degree of rejuvenation, turning back specific measures of age-related decline. The outline here is optimized for simplicity, cost, and ability to conduct the experiment without much outside assistance, rather than for maximal effectiveness. There are better candidate pharmaceuticals and better metrics that those settled on here, at least from the point of view of likely effectiveness, fewer side-effects, and relevance to the task at hand, but they require more work, more funds, more complicated logistics, and the assistance of laboratories and physicians. Given these self-imposed constraints, this does mean that the outline here ends up focused on repurposed chemotherapeutics, which make up the majority of the current senolytic drug candidates. That in turn means that side-effects and related risks to health are an important consideration. The purpose in publishing this outline is not to encourage people to immediately set forth to follow it. If you come away thinking that you should do exactly that, and as soon as possible, then you have failed at reading comprehension. This post is intended to illustrate how to think about self-experimentation in this field: set your constraints; identify likely approaches; do the research to fill in the necessary details; establish a plan of action; perhaps try out some parts of it in advance, such as the measurement portions, as they never quite wo Continue reading >>

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Diabetes Drugs Without A Prescription?

So you’re standing in line at the checkout of your local pharmacy, your shopping basket filled with soap, shampoo, maybe a snack and some aspirin. But you know you forgot one thing — what was it? Oh yes, your diabetes medicine. No worries; it’s sitting right next to the cash register, strategically placed so that people like you remember to replenish their supply. Far-fetched? Not as much as you might think. According to an article published last week in the Washington Post, the US Food and Drug Administration (FDA) is considering allowing certain drugs for diabetes, asthma, and migraines to be sold without a prescription. No outcome is certain at this point, and the scenario described above might never come to pass even if the FDA’s plans proceed; pharmacists might be required to dispense a drug even if no doctor’s prescription is required. But if all goes as planned, the way people receive drugs used to treat some common health conditions could change dramatically. According to the Post article, the FDA is interested in increasing access to established drugs that have been shown to be easy to administer and relatively low-risk. Since over-the counter drugs require no visit to a doctor and tend to be cheaper than even generic prescription drugs, people with no health insurance or limited coverage could benefit from removing prescription requirements. On several past occasions, the FDA has granted petitions from drugmakers to allow a prescription drug to be sold over-the-counter. Examples from the last decade include omeprazole (brand name Prilosec and others), a drug for gastroesophageal reflux disease; and loratadine (Claritin and others), for allergies. The FDA envisions potential customers filling out questionnaires on electronic kiosks in pharmacies, poss Continue reading >>

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New Metformin Generic Now In Pharmacies

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Diabetes—specifically type 2 or adult onset diabetes—is a growing epidemic in the United States, in part to the increase in obesity over the past 10 years. However, there are several medications that (with healthy diet and excercise) can help keep your blood sugar under control. Glumetza is the newest option to have a generic version approved, which should mean lower prices and more options for you in the near future. When will generic Glumetza be in pharmacies? Generic Glumetza (metformin ER) tablets are now available—you can fill your prescription at your regular pharmacy. How is generic Glumetza (metformin ER) available? Generic Glumetza is a tablet, available in 500 mg and 1000 mg strengths. Do I have more than one generic option for Glumetza? No. Lupin Pharmaceuticals is currently the only pharmaceutical company allowed to make the generic of Glumetza. They have been granted exclusivity for 6 months or 180 days. After that, you may start to see other companies creating their own generic versions (which should help bring prices down even further). Are there any similar alternatives to Glumetza? Yes! Extended-release metformin is actually available in three brand-name drugs, all of which now have generic alternatives: Glumetza, Fortamet, and Glucophage XR. Since the generic for Glucophage XR has been in pharmacies for quite some time, it may be significantly less expensive, especially if you’re paying out of pocket. Is there a reason why my doctor might still prescribe me Glumetza instead? Maybe—each version of metformin ER is different in the way it releases the medication into the body. For more information on the differences between Glumetza and Fortamet see our previous article. What are the most common side effects of generic Glumetza (Metformin HCl ER Continue reading >>

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