Just Started Taking Metformin - Keep Falling Asleep!
Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Just started taking metformin - keep falling asleep! My latest blood test showed that my diet wasn't doing enough to control my diabetes, so on tuesday I saw my doctor and was prescribed metformin. She also wanted me to start taking a statin, but only after I've seen how things go with the metformin, as I have M.E which can make you more sensitive to drugs. I have noticed I keep falling asleep a lot during the day and I've had much more muscle an joint pain since starting to take metformin. Although I have M.E I haven't had problems with falling to sleep during the day before and pain has been mostly more of a dull aching like you get when you have flu. This pain is worse, although not unbearable. Is it more usual to be sleepy and have muscle/joint pain when starting to take this drug? Of course this might not be a side effect at all. It could just be my M.E flaring. Tiredness is quite common when starting to take metformin, some people compare it to a mild case of flu, not sure about the muscle ache as I never experienced that symptom mine related primarily with tiredness, nausea and dirrhea, the tiredness passed in a week the dirrhea never really went away. After a year I changed to the slow release version of meformin, glucophage with this i have virtually no symptoms at all. if after a couple of weeks things dont improve it may be worth trying glucophage If you find that the muscle pain becomes severe i would speak to your gp, metformin has been known in rare cases to cause lactic acedosis Warning signs of lactic acidosis include fast and shallow breathing, diarrhea, severe muscle aches, cramping, unusual weakness or tiredness, or feeling cold. Continue reading >>
Metformin And Pcos: Everything You Need To Know
Metformin is a type of medication used to treat Type 2 Diabetes. Because there is a strong link between diabetes and PCOS, metformin is now commonly proscribed to treat PCOS. But should it be? What is the real relationship between metformin and PCOS? Can Metformin used for PCOS help lessen PCOS symptoms? Metformin used for PCOS: The Science PCOS is an infertility condition that often causes acne, facial hair growth, balding, low sex drive, weight gain, difficulty with weight loss, and mental health disturbances such as depression and anxiety in approximately 15% of women. It is also associated with a myriad of health conditions, spanning from diabetes to hypothyroidism and to heart disease. PCOS is, in short, not a condition to sneeze at. PCOS is a condition of hormone imbalance. With PCOS, male sex hormones such as testosterone and DHEA-S rise relative to the female sex hormones estrogen and progesterone. (…Roughly speaking – it’s complicated. For a full-blown account of the science of PCOS and how it affects you, see here.) Elevated testosterone is very often the primary culprit in causing PCOS. (But not always! For one of my most thorough accounts of other things that can cause PCOS, see here.) Insulin causes testosterone levels to rise because insulin tells the ovaries to produce testosterone. Basically, elevated insulin causes elevated testosterone, which causes PCOS. This is where metformin comes into play. Metformin lowers blood sugar levels below what they would otherwise be after a meal. This is because it intervenes with the liver’s interaction with and production of glucose. Insulin is the body’s way of dealing with blood sugar. If blood sugar is lower, then insulin will be lower, and thus testosterone will be lower. Metformin decreases blood sugar, Continue reading >>
Metformin, Oral Tablet
Metformin oral tablet is available as both a generic and brand-name drug. Brand names: Glucophage, Glucophage XR, Fortamet, and Glumetza. Metformin is also available as an oral solution but only in the brand-name drug Riomet. Metformin is used to treat high blood sugar levels caused by type 2 diabetes. FDA warning: Lactic acidosis warning This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects. Lactic acidosis is a rare but serious side effect of this drug. In this condition, lactic acid builds up in your blood. This is a medical emergency that requires treatment in the hospital. Lactic acidosis is fatal in about half of people who develop it. You should stop taking this drug and call your doctor right away or go to the emergency room if you have signs of lactic acidosis. Symptoms include tiredness, weakness, unusual muscle pain, trouble breathing, unusual sleepiness, stomach pains, nausea (or vomiting), dizziness (or lightheadedness), and slow or irregular heart rate. Alcohol use warning: You shouldn’t drink alcohol while taking this drug. Alcohol can affect your blood sugar levels unpredictably and increase your risk of lactic acidosis. Kidney problems warning: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug. Liver problems warning: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems. Metformin oral tablet is a prescription drug that’s available as the brand name drugs Glucophage, Glucophage XR, Fortamet, and Glumetza. Glucophage is an immediate-release tablet. All of the other brands are extended-r Continue reading >>
3 Things You Need To Know About Metformin
September 30, 2015 by Dr. Brooke in Be Better , Eat Better , pcos 3 Things You Need To Know About Metformin Metformin is recommended by doctors for women with PCOS that want to loose weight or otherwise manage their PCOS and insulin resistance. But there are 3 very important things that you need to know about it including the fact that it's not the only option! Let me first say, I dont hate Metformin for women with PCOS . For some women it really does help spur ovulation, control blood sugar and help with some weight management but.its not without its share of issues. And its definitely not the magic bullet for weight loss although its usually presented that way. How Metformin (or its generic form: Glucophage) Works Metformin is typically given with meals throughout the day, or more commonly now the extended release version is given once with dinner or at bedtime. While only having to pop a pill one time per day is always appealing, this once a day dosing (especially at bedtime) is where I see the most problems with my patients. It lowers both fasting and post meal glucose levels by decreasing the glucose absorption in your intestines after a meal; as well as decreasing the amount of glucose your liver makes for later use. It also does help improve insulin sensitivity by increasing glucose movement into a cell. All sounds good so far right? Not so fast, here are the most common issues I see in women using Metformin: Metformin is notorious for causing sometimes severe digestive issues including stomach pain or upset, nausea, vomiting, diarrhea and even a sense of body weakness or metallic taste in the mouth in some. And it is touted as not causing low blood sugar as many older blood sugar lowering drugs did, however I see it every day in my practice that Metformin can m Continue reading >>
How To Beat Pcos Fatigue
Being tired is the worst. In fact, the only thing that is worse than being tired is when you realize you are tired of feeling tired all the time. Fatigue is a vague symptom and therefore, it does not get much attention from PCOS experts. But if you ask one of the many women living with PCOS (including me) -fatigue is one of the most troubling symptoms of Polycystic Ovarian Syndrome. The fatigue I am talking about is different from boredom or being sleepy after a night of Netflix binging. It is a truly physical sense of exhaustion, where you might want to do something, but you just feel too worn out to make it happen. I’ve turned down wine nights with the girls and procrastinated on writing a blog post because fatigue has reared its ugly head. Today I am going to give you a practical approach to managing fatigue. But first I want to tell you to go to your doctor and get a check-up. In case my Lululemon crop pants did not tip you off- I’m a personal trainer and not a physician. Chronic Fatigue could indicate that you have another medical condition. Some the conditions common to PCOS women include: Thyroid Disease Auto Immune Conditions Sleep Apnea Diabetes B-12 deficiences (linked to long-term metformin and birth control pill use) So go to your doctor and rule out all of this stuff. My perspective on PCOS and Fatigue At the center of PCOS is a hormonal imbalance. Our bodies are already dealing with some level of hormonal dysfunction. Therefore, we’re probably more vulnerable to other environmental stressors like a poor diet, sleep deprivation, and unmanaged stress. I believe that fatigue is one way that your body communicates to you that something in your environment is not good for you. Better nutrition, good sleep hygiene, and stress management can reduce PCOS fat Continue reading >>
Does Metformin Make Anyone Else Super Sleepy?
The gastro effects can be minimized by sharply dropping your carb intake. And for me, I took the ER, but it gave me such a boost of energy, I switched from taking it in the evening to the day. It knocked out my falling asleep after meals situation. I would think that you make be having low blood sugar side effects from it, just at a guess. Have you checked your blood sugars when on the Metformin? Everyone's IR can behave differently. After switching my foods dramatically, I'm mostly able to not have the IR effects and have dropped the Metformin... Are you taking B12? My dr told me to take a B12 supement with my Metformin because the Metformin depletes out B12 levels. I take my B12 separately so I make sure I get the full absorption. Yes, Metformin, hormonal birth control or other hormonal supplementation, anti-seizure meds, anti-psychotic meds, antacids, and many others interfere. Make sure to have this checked any time the doc checks your bloodwork. I didn't know to check it and was severely deficient before I began treatment and have nerve damage that resulted. It's been less than a year since I started supplementing the B12, and I'm out of the continuing risk range, but I don't know yet if the nerve damage is repairable... I was told recently not to take B12 without the supporting B vitamins, or it would just deplete them all. I was told to get a complex called B-150, which is like a B-Complex vitamin, but I believe it has the full complement of B Vitamins. I haven't been able to find any info to substantiate this claim. Make sure to do bloodwork, rather than just waste your money supplementing without necessity...or overdoing something you aren't sufficient in. Make sure your pharmacist knows all your meds, even the OTC ones, to check for all possible interactions! Continue reading >>
Metformin (oral Route)
Precautions Drug information provided by: Micromedex It is very important that your doctor check your progress at regular visits, especially during the first few weeks that you take this medicine. Blood and urine tests may be needed to check for unwanted effects. This medicine may interact with the dye used for an X-ray or CT scan. Your doctor should advise you to stop taking it before you have any medical exams or diagnostic tests that might cause less urine output than usual. You may be advised to start taking the medicine again 48 hours after the exams or tests if your kidney function is tested and found to be normal. Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests. It is very important to carefully follow any instructions from your health care team about: Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems. Counseling—Other family members need to learn how to prevent side effects or help with side effects if they occur. Also, patients with diabetes may need special counseling about diabetes medicine dosing changes that might occur with lifestyle changes, such as changes in exercise or diet. Counseling on birth control and pregnancy may be needed because of the problems that can occur in pregnancy for patients with diabetes. Travel—Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would norm Continue reading >>
Metformin - Oral, Glucophage
are allergic to dapagliflozin or any of the ingredients in FARXIGA. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing. If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis. Your healthcare provider should do blood tests to check how well your kidneys are working before and during your treatment with FARXIGA Dehydration (the loss of body water and salt), which may cause you to feel dizzy, faint, lightheaded, or weak, especially when you stand up (orthostatic hypotension). You may be at a higher risk of dehydration if you have low blood pressure; take medicines to lower your blood pressure, including water pills (diuretics); are 65 years of age or older; are on a low salt diet, or have kidney problems Ketoacidosis occurred in people with type 1 and type 2 diabetes during treatment with FARXIGA. Ketoacidosis is a serious condition which may require hospitalization and may lead to death. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. If you get any of these symptoms, stop taking FARXIGA and call your healthcare provider right away. If possible, check for ketones in your urine or blood, even if your blood sugar is less than 250 mg/dL Kidney problems. Sudden kidney injury occurred in people taking FARXIGA. Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections (UTI), some that lead to hospitalization, occu Continue reading >>
What A High Blood Sugar Feels Like.
The American Diabetes Association cites the following symptoms as indicative of high blood sugar: High blood glucose [Editor’s note: Duh] High levels of sugar in the urine Frequent urination Increased thirst And if high blood sugar goes untreated? “Hyperglycemia can be a serious problem if you don’t treat it, so it’s important to treat as soon as you detect it. If you fail to treat hyperglycemia, a condition called ketoacidosis (diabetic coma) could occur. Ketoacidosis develops when your body doesn’t have enough insulin. Without insulin, your body can’t use glucose for fuel, so your body breaks down fats to use for energy. When your body breaks down fats, waste products called ketones are produced. Your body cannot tolerate large amounts of ketones and will try to get rid of them through the urine. Unfortunately, the body cannot release all the ketones and they build up in your blood, which can lead to ketoacidosis.” – ADA website But what does a high blood sugar feel like? Because when you see someone who is working through an elevated blood sugar, they may not look terribly out of sorts. But what is happening inside of them is real, and plays out in a myriad of ways for every person with diabetes. I’ve tried to write about it several times, but each high is different, and affects me in different ways: “It’s a thick feeling in the base of your brain, like someone’s cracked open your head and replaced your gray matter with sticky jam. I find myself zoning out and staring at things, and my eyeballs feel dry and like they’re tethered to my head by frayed ropes instead of optic nerves. Everything is slow and heavy and whipped with heavy cream.” – Oh, High! “There’s something about a high blood sugar that makes my body feel weighted down, l Continue reading >>
Does Metformin Make You Sleepy
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Metformin Makes Me Sleepy: Hydrochlorothiazide And Water Intake.
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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. What is in this leaflet This leaflet answers some common questions about metformin It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist or diabetes educator. The information in this leaflet was last updated on the date listed on the last page. More recent information on this medicine may be available. You can also download the most up to date leaflet from www.apotex.com.au. All medicines have risks and benefits. Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. Pharmaceutical companies cannot give you medical advice or an individual diagnosis. Keep this leaflet with your medicine. You may want to read it again. What this medicine is used for The name of your medicine is APO-Metformin 500, 850 or 1000 tablets. It contains the active ingredient metformin (as metformin hydrochloride). It is used to treat type 2 diabetes (also called non-insulin dependent diabetes mellitus or maturity onset diabetes) in adults and children over 10 years of age. It is especially useful in those who are overweight, when diet and exercise are not enough to lower high blood glucose levels (hyperglycaemia). For adult patients, metformin can be used alone, or in combination with other oral diabetic medicines or in combination with insulin in insulin requiring type 2 diabetes. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason. This medicine is available only with a doctor's prescription. How it works Metformin lowers high blood glucose by helping your body make better Continue reading >>
New Metformin Warning: Mandatory Supplementation With Vitamin B12
The most common medication used in women with PCOS is the insulin-sensitizer metformin. Research is strongly showing that long-term use of metformin and at high doses (1.5mg or higher daily) can deplete levels of vitamin B12. A deficiency of vitamin B12 can cause permanent neurological and nerve damage as well as mood changes and decreased energy. Here’s what you need to know to avoid a vitamin B12 deficiency if you take metformin. About Metformin Metformin is a medication that became available in the U.S. in 1995 for the treatment of type 2 diabetes. Metformin is the most widely used medication used to lower insulin levels in those with polycystic ovary syndrome. Other names for metformin include glucophage, glucophage XR, glumetza, and fortamet. Metformin lowers blood glucose levels in three ways: It suppresses the liver’s production of glucose. It increases the sensitivity of your liver, muscle, fat, and cells to the insulin your body makes. It slows the absorption of carbohydrates you consume Metformin use may affect the absorption of vitamin B12 possibly through alterations in intestinal mobility, increased bacterial overgrowth, or alterations of the vitamin B12-intrinsic factor complex. Metformin can cause a malabsorption in B12 due to digestive changes, which leads to the binding of B12-intrinsic factor complex (intrinsic factor is needed to absorb B12 in the gut) and a reduction of B12 absorption. Vitamin B12 Deficiency in Metformin Users The largest study thus far to examine the link between metformin and vitamin B12 is the Diabetes Prevention Program Outcomes Study (DDPOS). This study looked at B12 levels of individuals with prediabetes who took 850 mg Metformin 2x/day and compared them to those taking a placebo. At 5 years, 4.3% of the metformin users had Continue reading >>
Do You Feel Tired All The Time Or Is It Just Me?
Do you feel tired all the time or is it just me? I agree with the Vitamin D3. As long as I take this along with a healthy, balanced diet throughout the day, I don't feel sluggish. I also find that if I eat every 4 hours with an afternoon snack at around 3:30pm (when it really hits me sometimes), I tend to have more energy. I'm not sure if it's from PCOS or not. I started taking a vitamin D and a calcium/magnesium/zinc supplement and found that helped a lot with my fatigue. Also making sure I stick to a regular sleep schedule helped a lot too. I also take an iron supplement once a week and that seems to help as well. I agree with SARAHTESSA...once you've had your thyroid & vitamin levels checked, I would look into insulin resistance. I've been diagnosed with PCOS for years, and always had crippling fatigue, even after therapy reduced my depression symptoms. When my new OBGYN discovered I was insulin resistant, I started food-logging and realized that 70-80% of my daily nutrition was from carbs! That's not good for anyone, but especially not for people suffering from IR. Just cutting my carbs down to 50-55% of my daily values made a HUGE difference in my energy & my mood. I've probably had IR for a long time, but my regular doctor never thought to check for it. Constantly being told that "you are obviously depressed" actually made me finally get depressed! I knew that something was wrong for the longest time and I was continually told I was depressed. Just take an antidepressant. The antidepressants actually triggered my biggest weight gains...which of course, made the depression twice as bad. I felt so much worse about myself after being treated for the depression I supposedly had! Once I got with the right doctor and started figuring out my diet and what additional sup Continue reading >>
Dealing With Diabetes Fatigue
“My days have been getting shorter,” Ron (who has Type 2 diabetes) told me. “I sleep ten hours a night and still need naps in the day. Even when I’m awake, I’m dragging. What can I do?” Ron’s doctor wasn’t much help. At his last appointment six weeks ago, Ron’s A1c was 8.1, and the doc started him on nateglinide (brand name Starlix), but his energy level hasn’t improved. At family picnics, he just watches or naps while the others play softball. “I’m starting to feel depressed, like life is passing me by” he told me. Excessive tiredness like Ron’s is often called fatigue. It’s one of the classic symptoms of diabetes and many other illnesses. But what causes it and what can you do about it? Most experts blame insulin resistance for the fatigue. If your cells are resisting glucose, they won’t have enough fuel, so they tire out. At the same time, the glucose level in your blood will be higher than normal, so blood flows less well (similar to if there were sugar in your car’s gas tank), which could also be tiring. Hypoglycemia (low blood glucose) can also cause fatigue. Blood glucose is far from the whole story, though. Inflammation makes people very tired. Part of the inflammatory response includes cytokines and white blood cells that influence the nervous system and tell us to sleep. That’s why people are so tired with the flu; our immune systems are trying to get us to rest. If you have chronic inflammation, which many people with diabetes do, that could cause fatigue. Infection is another source of fatigue. Our bodies need all the energy they can get to fight the invading germs, so less energy is available for other things. Infection also causes inflammation and can raise blood glucose levels. So someone in Ron’s situation should inv Continue reading >>