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Metformin Bodybuilding Fat Loss

Metformin And Bodybuilding: Actions, Uses And Benefits

Metformin And Bodybuilding: Actions, Uses And Benefits

Metformin and Bodybuilding: Actions, Uses and Benefits Over the last few decades Metformin has been used exclusively as a type 2 diabetes treatment. However, currently the drug is extremely popular among bodybuilders due to a range of benefits it produces on the body. One of the crucial factors that presupposed the popularity of the treatment is Metformin and growth hormone relation. The medication provides a person with an ability to fight growth hormone induced insulin resistance. While the advantageous action of Metformin of the human physique is an undeniable fact, a rapidly growing number of customers are investigating differences in the drug effects depending on the dose, intake periodicity and other peculiarities. Advantages of Metformin Treatment Course for Bodybuilders While Metformin course is ultimately useful for improvement of type 2 diabetes symptoms, it can boost multiple other body functions. In this respect, bodybuilders undergo Metformin program in hope to benefit from: Stimulated insulin receptors. Metformin helps muscle cells to stay sensitive to insulin produced within the body Increased muscle mass. Combining Metformin intake with carbohydrate diet will result in more rapid muscle growth, while muscles will also be comparatively fuller and stronger. Loss of appetite. One of the common reactions of the organism on Metformin is appetite suppression. This peculiarity suits bodybuilders who stick to ketogenic diet. Eliminated fat storage. While Metformin prevents the body from fat storage, bodybuilders will enjoy their carbohydrate heavy meals without any fears for future consequences. Despite a range of positive effects Metformin produces in the body, one should follow the prescribed dose to ensure high safety level of the treatment course. The drug Continue reading >>

Metformine...good For Fat Loss

Metformine...good For Fat Loss

View and discuss the latest research articles and FAQ's as well as numerous Detailed Drug Profiles Want More? We have a full site section dedicated to Anabolic Steroid Articles and Anabolic Books From a long time ago in a Galaxy far, far away A good study and a clear explanation about why add glucophage in your cutting cycles. Metformine activate the AMPK.This enzymatic switch is activated with fisical training and send the imput to burn more fats and more carbs to the muscle fibers to produce more energy. This is a lately discover of the professor Grahame Hardie,at Cellular Signalling next to Dundee univeristy. Also metformin is know as a good appetite suppressor. Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: an in situ microdialysis study. AU: Flechtner-Mors-M; Ditschuneit-HH; Jenkinson-CP; Alt-A; Adler-G AD: Department of Internal Medicine, University of Ulm, Germany. [email protected] AIMS: Metformin has been reported to decrease the plasma concentrations of non-esterified fatty acids in Type 2 diabetic subjects. This study investigated the effects of metformin on basal and catecholamine-stimulated lipolysis in abdominal subcutaneous adipose tissue of obese, hyperinsulinaemic, hypertensive subjects. METHODS: Fourteen subjects with severe obesity (12 female, two male, age 35.4 +/- 4 years, body mass index 48.2 +/- 2 kg/m2, body fat mass 63.3 +/- 5 kg) were rec***ted. Glycerol and lactate concentrations were determined in the presence of metformin and after administration of catecholamines using microdialysis. Simultaneously, blood flow was assessed with the ethanol escape method. RESULTS: Glycerol release was lowered by metformin during the 3-h experiment (P<0.01). Continue reading >>

Metformin For Fatloss

Metformin For Fatloss

Submitted by RonnyT on Wed, 2012-11-07 12:53 Metformin (Glucophage) for Weight Loss and Bodybuilding Metformin, sold under the trade name Glucophage, is used to treat diabetes, but several studies show that it also helps non-diabetics to lose weight by reducing hunger (1). You may be overweight because your body makes too much insulin, especially if your store your fat primarily in your belly. When you eat, your blood sugar level rises. The higher it rises, the more insulin your pancreas releases. Insulin makes you fat by acting on your brain to make you hungry, your liver to manufacture fat, and the fat cells in your belly to fill with fat. So the treatment for this type of obesity is to avoid foods that cause the highest rise in blood sugar and to take medications that prevent your blood sugar levels from rising too high. Avoid bakery products, pastas and all foods made from flour, fruit juices and everything with added sugar. Eat fruits and root vegetables such as potatoes only with meals. After you eat, sugar goes from your intestines into your bloodstream, and then immediately into your liver. Then your liver releases sugar back into your bloodstream to cause your blood sugar level to rise. To keep blood sugar levels from rising too high, your pancreas release insulin into your bloodstream. Insulin makes you hungry all the time and causes your liver to convert extra calories to fat and it constricts arteries to cause heart attacks. You need insulin to keep blood sugar levels from rising too high to cause diabetes, nerve damage, heart attacks, strokes and kidney damage. Glucophage reduces sugar release from your liver to prevents blood sugar levels from rising too high, so your body doesn't need to produce as much insulin that makes you hungry and causes your liver Continue reading >>

My Personal Experience With Metformin (glucophage): A Great Cutting/anticatabolic Drug.

My Personal Experience With Metformin (glucophage): A Great Cutting/anticatabolic Drug.

My personal experience with Metformin (Glucophage): A great cutting/anticatabolic drug. My personal experience with Metformin (Glucophage): A great cutting/anticatabolic drug. Welcome to the EliteFitness.com Bodybuilding Site! Please join this discussion about My personal experience with Metformin (Glucophage): A great cutting/anticatabolic drug. within the Anabolic Steroids category. Excerpt: Tried Glucophage (Metformin) to cut a little. Metformin is an antidiabetic drug, it does several things: 1. Reduces carbohydrate absorption in your intestines by about one third, so you decrease total calories, and insulin release. 2. Reduces insulin resistance, so your body produces a little less insulin, which decreases fat storage. 3. It reduces gluconeogenesis, that is sugar formation from amino-acids, thus reducing muscle breakdown during fasting. Read more or register here to join the discussion below... My personal experience with Metformin (Glucophage): A great cutting/anticatabolic drug. Tried Glucophage (Metformin) to cut a little. Metformin is an antidiabetic drug, it does several things: 1. Reduces carbohydrate absorption in your intestines by about one third, so you decrease total calories, and insulin release. 2. Reduces insulin resistance, so your body produces a little less insulin, which decreases fat storage. 3. It reduces gluconeogenesis, that is sugar formation from amino-acids, thus reducing muscle breakdown during fasting. I started with a very low dose of 125mg (1/4 of a 500 mg tab), and went up to 850 mg (one 850 mg tab). Now I always take it at night, preferably before dinner, since it upsets your stomach a little bit, when you start taking it, or when you increase the dose. Have lost 12 pounds in less than 3 weeks, incredibly, most of them fat, have reta Continue reading >>

Metformin Infomation, Dosages, Timing Etc? Anybody?

Metformin Infomation, Dosages, Timing Etc? Anybody?

Been looking into adding metformin , i understand it is a very useful drug for insulin sensitivity and that the carbohydrates with meals go to muscles instead of fat... What dosage with the split? i belive to be during meals? I've just started taking it. I try and get 1500mg a day. Usually one or two in the morning and one about 6pm i was also taking 500mg a day , usually just before or after a meal. some folk get the runs taking with empty stomach and i did too at first but it stopped after few days you take it with your main carb meals. so usually 1500mg/day. it makes your body more sensitive to insulin, so that your body releases less insulin to keep your BG reading at 6.0-7.0 after a meal. The reason this is good is, that when excess insulin is released,it promotes storage of nutrients- first in the muscle cell, then in the fat cells; excess insulin also keep your body in an anabolic state, but prevents burning of fats. thats what insulin does... so you can see why it stops fat burning. However, metformin doesn't stop you getting fat, what it does is prevent insulin resistance: many people who overeat refined carbs (i.e bulking BBs) may not be medically insulin resistant, but they may not be optimal. 1. helps get into keto on a Cyclic ketogenic diet 2. it helps regain sensitivity after a 'slin cycle it can help smooth the effect of one junk meal in a diet every now and again... BUT IT DOESNT MAKE YOU LEAN... If you are dieting, then you'd be on med-low carbs, with no simple sugars (high GI) so it wouldnt help anyway.... many people who overeat refined carbs (i.e bulking BBs) may not be medically insulin resistant, but they may not be optimal. 1. helps get into keto on a Cyclic ketogenic diet 2. it helps regain sensitivity after a 'slin cycle it can help smooth the Continue reading >>

Tip: What You Need To Know About Berberine

Tip: What You Need To Know About Berberine

Tip: What You Need to Know About Berberine A Supplement That "Mimics the Effects of Exercise" Exercise in a bottle? That's how some marketers are describing berberine. Yes, that's over the top... and potentially criminal. But it's not completely inaccurate either according to clinical trials. Berberine is a compound found in many different herbs like goldenseal, Chinese goldenthread, and philodendron. In studies, it's proving to be a heavy hitter when it comes to regulating blood sugar and managing weight, among other things like cancer prevention and gut health. So far, 2,800 studies have been done on the compound, many focusing on its effects on Type 2 diabetes. It appears to rival Metformin when it comes to blood glucose and blood lipid levels. How? Good question. AMPK (AMP-activated protein kinase) is an enzyme responsible for maintaining energy balance in cells. AMPK helps balance blood sugar levels, fats in your blood, and energy levels. Turning AMPK off equals catabolism or breakdown mode. This can include the symptoms of metabolic syndrome, like high blood sugar, energy imbalances, bad blood lipid levels, and diabetic symptoms. When you're in catabolism, you aren't building muscle or recovering, which means your gains will suffer. Turning AMPK on equals anabolism or build-up mode. Turning on AMPK lowers blood glucose levels, normalizes blood lipid levels, improves energy, and reduces diabetic symptoms. It puts cells into gains mode. And berberine appears to turn on AMPK. Test tubes: Berberine was shown to influence certain genes that regulate metabolism. There are certain genes that, when turned on, can cause adaptive thermogenesis (AT) or the slowing down of metabolism. Berberine may put these genes into a headlock and reduce their ability to ruin your waistli Continue reading >>

Experience Of Metformin Hcl (glucophage)

Experience Of Metformin Hcl (glucophage)

i have been using metformin on my refeed/cheat days while dieting with good results. i get an awesome pump. I also have started adding it to my medium day which is 2moro. theirs a few threads on it and loads over on promuscle.com so have a look around. Already done alot of research from a variety of sources including UKM.. I was after more personal opinions on the med TBH ive used it also and it does give you that fuller feel or pumped if you will.one thing though is that it makes me s**t bricks twice a day ?????????.i usually take 1000mg a day before meals gastrointestinal upset if you take it on empty stomach.. took it 3 times a day, after carb meals.. 500mg.. i've also used it to induce ketosis in 2 days.. fcuk the 1wk hell you'd have to go through otherwise.. I forgot to add i alsol used it to introduce ketosis in 2 days. worked well and much less dangerous than using slin. Really good for cutting. When I use it, I can not seem to gain fat no matter what I eat. Used it with GH before, and dropping body fat was extremely easy. I've used it many different ways. Daily use is the best for cutting. Used it with cheat meals only while cutting before, and it kept fat off, but not nearly as amazing results as when using it daily. Really like the stuff - cheap, keeps me full, nothing in the way of hypo obviously, seems to predetermine me to stay leaner as I gain wieght. Love the fullness it gives, and as someone above says, it gives really good pumps. Cant wait until I am very lean again, I think it will be the ideal chem for helping carbup, cant wait to experiment. On the negative sides I have noted stomach upset/heartburn if not taken with food, so I take it immediately after meals. I have also noticed when I jsut start taking it, I get a headache later that same day, but Continue reading >>

The Dirty Road Too Forcing Fat Loss

The Dirty Road Too Forcing Fat Loss

Now, we all wish there was this magic pill that would melt the fat away while we sit on the coach drinking our beer Reality is, there are a few dirty tricks one can apply to melt the fat away. Some of it will work by sitting on the coach and some of them would need a caloric restricted diet and training to work effectively. So either way there is hope for the coach potatoes wishing for a fat melting pill although it is a bit of a dirty road! Dirty trick 2, 3, 4 and 6 will work for the coach potatoes. Dirty trick 1 and 5 must have a caloric restricted frequent meal plan in place and a training system. But ALL dirty tricks will work much more effective when they have acaloric restricted frequent meal plan in and a moderate to intense training system in place. Please note the fact that I discuss these dirty methods, does not mean I approve of any of it. Neither does it mean I am using it or have ever used it in the past! This article is meant as an informational study into what last alternatives there are legal and otherwise to control weight for those not prepared to put in the effort with a healthy living and lifestyle. Knowledge is power and to suppress it simply because you disagree with what is being said is not a healthy road to enhance your knowledge base and understanding. Now as you all know, I am not sponsored by any supplement company or brand out there and regularly shoot down overrated/worthless supplements so what I am saying here is unbiased and cutting to the bone. On the subject of supplement companies, just about ALL the supplements claiming magical fat-loss and other fantastical claims are close to worthless. You will spend a lot of money for something that will make a very, very small difference. You should either just focus on your diet/training/core Continue reading >>

Metformin With Fat Loss Goal In Mind - Anabolic Steroids Discussion And Bodybuilding Forum

Metformin With Fat Loss Goal In Mind - Anabolic Steroids Discussion And Bodybuilding Forum

Anabolic Steroids Discussion and Bodybuilding Forum Automatic Translations (Powered by Yandex ): Metformin with fat loss goal in mind - 08-19-2014, 04:52 PM So a friend of mine got her Rx dose of metformin upped and no longer needed the smaller 500mg tabs she had left so she gave them to me. From what I have read around they can be a great tool to control appetite as well as fat loss . I have read a few posts talking about using them with meals to increase insulin sensitivity and help utilize carbs more efficiently. Guys are often talking about using 500mg with regular meals and 1000mg with high carb meals. Where I am mainly interested in the fat loss usage of the drug I'm curious if this same dosage and timing is effective/best for my current goals.. Also how long would be an ideal duration to use it? She only had 52 left in the bottle.. So at that dose I'd only have enough for about 17 days of constant use. A little about me: 5'10" 230lbs about 20% bodyfat I am currently on prescription TRT at 100mg test cyp/week in my last 12 week cut lost about 30lbs with about 6% bf loss. So I have been enjoying the summer and am going to hit another big cut starting September 29. Would it be more beneficial to use the metformin during the cut or while in a bulking diet to keep lean? Hope this is a good section for my post! Any advice is helpful.. What is the Protocol? - 08-24-2014, 07:51 AM Use it to cut and get as lean as possible. That will make your body more responsive to your next bulking phase. We all know that no matter what size you are, being as lean as possible always looks better. And if you want more, I just checked the online pharmacy I normally use and generic metformin is readily available. It's not terribly pricey, but not really cheap either. How does one lean ou Continue reading >>

Evolutionary.org Forums

Evolutionary.org Forums

Hi everybody i hope you're all fine , please i have a question for people who have informations or experience with Metformin i wanna lose fat with it , firstly because it's cheap in my country ( Morocco) it coasts : 3 dollars for 50 tabs it's name is : Glucophage 500 mg ! i didn't want to use clenbuterol or Dnp because it's expensive in my country so can some one please tell me how to use Glucophage 500 mg for lose fat ? can some one give me protocol of how to use it correctly ? My stats i'm a skinny fat with 168 cm of height and 67 kg , 24 years old I'm waiting your answers guys , and another things i read that it's possible to gain muscles and pump gain with Glucophage is it true ? You shouldn't just be taking Glucophage without the Supervision of a Doctor. This Drug is meant for Type II Diabetics, or Pre-Diabetics. But again, only a Doctor can determine if this Drug is right for you. There are certain Pre-Conditions that would Preclude you from being a Candidate for Glucophage. Such as Kidney or Liver Disease, or a History of Heart Issues, or a Recent Heart Attack. And then even if you are Healthy, you can run into Life Threatening Problems. Like Lactic-Acidosis, which can be Life Threatening if left untreated. And without a Doctor to supervise you, you are just asking for problems..................... JP Hi everybody i hope you're all fine , please i have a question for people who have informations or experience with Metformin i wanna lose fat with it , firstly because it's cheap in my country ( Morocco) it coasts : 3 dollars for 50 tabs it's name is : Glucophage 500 mg ! i didn't want to use clenbuterol or Dnp because it's expensive in my country so can some one please tell me how to use Glucophage 500 mg for lose fat ? can some one give me protocol of how to use Continue reading >>

Metformin Year Round? - Page 4 - Professional Muscle

Metformin Year Round? - Page 4 - Professional Muscle

I started metformin on a contest diet. I have kept it though lean bulk. My insulin sensitivity is amazing right now. I switched my cardio to before weights. On my last set I take 500 mg then go home and erta 50 pro 120 slow acting carbs. 1 cup oatmeal and 2 english muffins. Within 15 minutes I am asleep. I also take 500 upon waking. I am a big fan and have been making great gains at 400 carbs a day. 5/11" 202 shredded on stage last year currently 240 had a god amount of fat creep in right after contest as I went from 60 carbs to 250 overnight. I see no reason to ever stop I swear I have heard Matt Porter mention it can have negative effects on the liver. I've never specifically looked it up...but also NEVER heard that anywhere else. Clarifying metformin's role and risks in liver dysfunction. - PubMed - NCBI most concerns surround lactic acidosis and have been found to be non-factors in a healthy population. basically if you already have liver disease or kidney failure then no you don't want to take it, otherwise it has not been found to be harmful Are most of you guys using the normal version or the er? I have heard the normal is better but I only have the er version I am not aware of any mechanisms by which metformin might negatively affecting muscle growth to any significant degree. I am not saying they don't exist--I am just not aware of them. However, I do know that insulin resistance can have a profoundly negative impact on muscle growth, while also increasing the likelihood of fat gain. Unfortunately, insulin resistance is all too common in off-season bodybuilders. Growth hormone, insulin, and the typical off-season diet all have a negative effect on insulin sensitivity, especially when all 3 are risk factors are present at once. High doses of these drugs just ma Continue reading >>

Can Metformin Help With Weight Loss?

Can Metformin Help With Weight Loss?

Bottom Line: Yes. About 2 to 9 kg (4 to 20 pounds) according to the studies and this fits my clinical experience. I want to give my patients the best shot possible when trying to lose weight (and keep it off). This may or may not include giving them medicines along the way. Our bodies are working against us so we must work against them (as safely as possible). Most approved weight loss medicines work in the brain to help us control our appetites. They can be pricey (unless generic, which are approved for short-term) and their long-term effects are unknown. There is one medicine that has been prescribed by weight loss doctors and used by bodybuilders for years despite not being approved for weight loss with a very strong safety record. That medicine is metformin. (Or as my Siri has written in the past, Matt Foreman). How to take it: Start with 500 mg tablet with breakfast (some say start with dinner). If you tolerate it after about a week or two, try 500 mg with breakfast and dinner. After another week or two go to 1000 mg with breakfast and dinner. Who takes it?: It is the first-line drug treatment approved for type 2 diabetes. However, it is also commonly used in PCOS (polycystic ovarian syndrome), prediabetes (and those with insulin resistance), those taking antipsychotics looking to minimize weight gain, and adolescents/adults looking to lose weight some weight loss. There are anecdotal reports of athletes and bodybuilders taking it as well. How does it work?: Metformin helps your muscles take in sugar (increases insulin sensitivity) and slows your liver’s sugar production (decreased hepatic gluconeogenesis). The mechanism is likely a peripheral activation of AMPK (AMP-activated protein kinase) and alteration of the gut microbiome and increases in GLP-1. You can re Continue reading >>

Metformin And Muscle Growth

Metformin And Muscle Growth

by Mike Arnold Over the last few years insulin sensitizers, and metformin in particular, have become quite popular among bodybuilders due to their many positive effects, one of which is the ability to combat growth hormone/exogenous insulin induced insulin resistance. While their physique and health enhancing benefits are undeniable, many have begun utilizing these compounds indiscriminately, adhering to a more is better philosophy in terms of dose, frequency of use, and the number of compounds employed. This may be advantageous with some drugs, but is it true in this instance? Insulin sensitizers are rather unique in that many of their positive and negative effects are mediated through a single pathway; an enzyme known as adenosine monophosphate-activated protein kinase, or AMPK for short. Acting as a cellular energy regulator, AMPK is responsible for maintaining cellular energy homeostasis via the regulation of ATP levels. When the body is exposed to stresses that deplete ATP, such as heat shock, or much more commonly, low blood glucose and hypoxia as a result of diet and exercise, this enzyme is activated. As a result, processes which involve ATP consumption (fatty acid and cholesterol synthesis) are turned off, while processes which involve ATP production (fatty acid and glucose oxidation) are turned on in an attempt to replenish cellular energy levels. This has a number of beneficial effects. It improves insulin sensitivity (via improved insulin receptor function and increased Glut-4 translocation), increases glucose uptake into muscle tissue, simulates fat loss, improves cholesterol values, and results in an overall improvement in metabolic health. With such a diverse number of benefits and with all of them directly applicable to the goals/circumstances of a bodyb Continue reading >>

Stubborn Fat Loss-insulin Resistance & Metformin

Stubborn Fat Loss-insulin Resistance & Metformin

This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies. Learn More. Welcome to the All Things Male Forum. Please sign up and join the conversation. It's free! Anyone using metformin (Glucophage) for helping restore insulin sensitivity and to help with stubborn fat loss due to chronic insulin resistance (IR)? I am 53 now and have tried it all (except HRT which I will be starting soon!) and have done everything "right" for the last 4 years (i.e. moderate carb, low carb, IF, paleo, counting calories, keto) to no avail in reducing bodyfat - which has actually worsened for no apparent reason (@ nearly 30% up from 25%) despite keeping my ultra-clean diet, supplements, and regular workouts. As a result, there has a been a cumulative effect from such bodyfat to the point I am getting warning signals (i.e. fatty liver, chronic higher BP, sleep apnea, elevated CRP, LDL-P and APO B, low free test, and lately, tinnitus probably caused by higher BP). It is no longer just a matter of esthetics. I need to do something - and I need to do it FAST. I would venture to say I have been struggling with a compromised RMR - and the answer to my dilemma lie in my low thyroid function and its crack baby, IR. I have been struggling to optimize my sluggish thyroid with T3 monotherapy; I will be experimenting with adding dessicated thyroid next to get the added components. I do not have a conversion block, by the way. I don't have diabetes and my a1c (5.3) and FBG (87) are normal, but I think my day's BG is somehow staying elevated and not allowing fat loss. Lipolysis is impaired. Sort like I'm permanently stuck in the anti-fat-loss gear. My sense is that it has been over many years - even decades that low thyroid function impaired my ability to maintain ins Continue reading >>

Metformin Place In Bodybuilding! [archive] - Bodybuilding | Steroids | Muscle | Powerlifting | Fitness

Metformin Place In Bodybuilding! [archive] - Bodybuilding | Steroids | Muscle | Powerlifting | Fitness

So I currently have a buddy who swears by this. For multiply reasons. He claims , quote " I can eat anything and not gain any fat what so ever" So i been doing some research as i have a fair amount of access to a lot of this drug. Mainly use to treat type 2 diebites but a lot of brothers are claiming that this is a very benificial drug. Full muscles: Muscles will grow fuller when metformin is used with high carbohydrate diets. Lack of fat storage: Metformin helps prevent fat from being deposited, so you get full benefits from carbohydrate heavy meals, without worrying to end up storing fat. This is why diabetics say they lean out on this drug. Insulin receptors: Metformin helps keep muscle cells sensitized for insulin that the body produces. Appetite suppression: This drug will limit hunger, so its perfect for those doing a ketogenic diet. Furthermore, on re-feed days it makes a perfect addition to your carbohydrate heavy cheat day. Pumps: Bodybuilders claim to get tremendous pumps when using metformin. However, there are a fair amount of side effects you guys should be aware of. These are some of the common side effects I have come accross from researching the drug. Nausea, Vomiting, Gas, Bloating, Diarrhea, Appetite Suprression The half life is listed as 4-6 hours. However, there are slow releasing extended tabs available. Bodybuilders should stick to the faster acting version as mentioned above. Below is a copy and paste from a brother article with a bit more knowledge on this. Full muscles can be achieved if 500-1000 milligrams (mgs) are taken within 1 hour after a large carbohydrate meal. The more carbohydrates there are in the meal, the higher the dosage should be taken, never exceeding 1500 mgs at a time. Nevertheless, metformin can be taken with as many high ca Continue reading >>

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