Link Between Statins And Diabetes

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Statins Linked To Increased Risk Of Type 2 Diabetes

Lowering the "bad" form of cholesterol with statin drugs could increase diabetes risk, a study suggests. Scientists found that people with naturally lower levels of low-density lipoprotein (LDL) cholesterol were less likely to develop heart disease but slightly more vulnerable to Type 2 diabetes. Reducing LDL levels by taking statins may have the same effect, they believe. Lead researcher Dr Michael Holmes, from Oxford University, said: "What we've shown in this study is that the role played by blood lipid levels in disease is a complex one. "While the effect of taking LDL cholesterol-lowering drugs such as statins may slightly increase a person's risk of developing diabetes this effect is greatly outweighed by their benefits in the form of preventing people from suffering from a life-altering heart attack or stroke." The team analysed large data sets of information about genetic make-up to tease apart the possible effects on heart disease and diabetes risk of LDL and so-called "good" cholesterol, high-density lipoprotein (HDL), which is said to be protective. They also looked at the influence of triglyceride blood fats which are associated with heart disease. Cases of heart diseas Continue reading >>

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  1. HackTwat

    What type of insulin should I use for bodybuilding
    What type of insulin should I use for bodybuilding? Humulin R and Humalog are the only insulin's I recommend because they act fast and are out of the body fastest(this makes them the safest). I have never used Humalog but understand that aside from quicker onset and half-life it is essentially the same.
    Why do I want to use insulin?
    Insulin has been called "Anabolicus Maximus" by some gurus of the bodybuilding world. Insulin can give you greater gains than you have ever had using anabolics alone. Insulin, in combination with androgens and resistance exercise, may trigger maturation of satellite muscle cells (small, more or less useless cells that are held in reserve, which do not contribute to muscular strength) into mature muscle cells that do contribute to muscular size and strength. How freakin cool is that. Hyperinsulinemia has been shown to stimulate protein synthesis in isolated limb infusion experiments , these anabolic properties seem to be the result of insulin binding to IGF-1 receptors.

    Isn't taking insulin dangerous?
    Insulin safety
    1. Do not use slin alone have a training partner or girlfriend who's not using slin hang around with you from the time you take the slin to about 2.5/4 hrs after.
    Assuming that Humalog is used and shot IM (intramuscular) the time is just 2.5 hours.
    2. Tell you're partner to look for anything out of the norm for your personality and have a list of questions like your ssn or address etc that they can ask you. Don't joke around, and answer them without shit, because if you cant answer or refuse to answer it could be a sign of hypoglycemia(low blood sugar). Symptoms of hypoglycemia include disorientation, headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea.
    Personal side note, do not take a shower while slin is active, it can be very hard to pick up the sides...
    3. If you cant/wont answer or are feeling the symptoms of hypoglycemia they should be prepared to feed you carbs like pancake syrup, coke, sugary stuff. I bought glucose tablets at walmart. kind of like candy but gets in the blood faster and dissolve quickly. these are for diabetics ask at the pharmacy.
    4. Have your partner know that if they suspect low blood sugar and cant convince or force you to consume carbs until your better. CALL 911 and ask for an ambulance and tell the truth to the operator... that they suspect you are in insulin shock and explain when they get there(the ambulance guys not the cops) that you are not diabetic but using insulin for anabolic purposes. Have the type of slin, the dosage and carbs consumed recorded to give the paramedic. They will save your life. Then you refuse transport to the hospital and eat. It might be a good idea to make sure your house is "clean" before every workout just in case the bad thing happens and the cops ask a lot of questions.
    5. Why so much preparation for the possible problem?? insulin can kill you in minutes if you go down!!
    6. Take the carbs and protein together immediately after injecting the slin(don't take chances trying to time out 15 min after injection). Take the protein with the carbs because the protein is pushed into the muscles with the slin also(creatine too).
    This HAS TO BE whey protein, and the sugar should be dextrose. The whey should be taken in water... you want a fast absorbing protein at this point, so do not have a meal here.
    7. Before an hour passes you should eat a normal balanced meal(high protein low fat with carbs).
    8. Consume another small high protein medium carb low fat meal at 2.5 hours after the injection. Congrats you lived.(keep some Gatorade on hand just to make sure because your not going to have a lifeline)
    9. YAWN... Don't go to sleep within 4/6 hours of using insulin since you can develop hypoglycemia while asleep and not have warning signs.
    Ok I'm not scared I still want to use insulin...
    Where do I keep it? (STORAGE)
    The FDA requires that all preparations of insulin contain instructions to keep in a cold place and to avoid freezing. The refrigerator is a good spot. Unrefrigerated insulin can be kept of 28 days as long as it stays in a cool and dark place.
    Where/how do I inject insulin?
    The best sites for insulin injection are in the subcutaneous tissue of the abdomen(avoid the area close to bellybutton) .Usually, you should not inject within 1 inch of the same site within 1 month. The arms and legs can also be used, but insulin uptake from these sites is less uniform. Insulin should be injected subcutaneously only with a U-100 insulin syringe. "B-D ultra-fine" insulin syringes are good. Insulin syringes are available without a prescription in many states. If you cant purchase the syringes at a pharmacy, you can mail order them. Using a syringe other than a specific insulin syringe is dangerous since it will be difficult to measure out the correct dosage.
    NO this needs to be an IM (intramuscular) shot. Subc is not good for what we use it for, IM cuts the duration of the insulin in half. Also a good place to inject is a place with low body fat. ie tricep, bicep and the tear drop on the quad.
    How much insulin should I take?

    I recommend never using over 10IU. 10IU is enough to make you grow.
    In general Dosages used are usually 1 IU per 20 pounds of lean bodyweight. So a 220lb bodybuilder with 9% body-fat would use 10iu of insulin(aprox200lb lean mass/20 = 10iu). But even experienced insulin users shouldn't use max dosage at the beginning of an insulin cycle. First-time users should start at a low dosage and gradually work up. For example, first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout until you reach your calculated dose or determine a maximum personal dose(some people are more sensitive to insulin sides like hypoglycemia). This will allow the athlete to determine a dosage he can safely use. Insulin dosages can vary significantly among athletes and are dependent upon insulin sensitivity and the use of other drugs. Athletes using growth hormone and thyroid might have higher insulin requirements.
    When do I take insulin?
    It is my opinion that you should only take insulin after a work out, never before or when not working out, because before a work out you could crash and die during the workout and when your not working out it makes you fat. Some people disagree with this. IF you want, get some info from them and try it. But remember I told ya so.
    When do I eat after using insulin?
    Immediately!!! DO NOT TRY TO TIME YOUR CONSUMPTION OF CARBS!! You should immediately take a carbohydrate AND protein drink after taking you're insulin. I've stated this twice because it is very important. Even experienced insulin users can get a surprise now and then.
    Eat a meal at about an hour after using insulin. Consume another small high protein medium carb low fat meal at 2.5 hours after the injection. keep some Gatorade on hand just to make sure. Remember that insulin can still work much later so be careful and eat if you feel hypoglycemia symptoms.
    Once again no first meal it needs to be whey protein/dex in water...
    What do I eat after using insulin?
    Some people recommend a zero fat intake for 4 hours after taking insulin. I do not disagree with this. But if your bulking you can be a little relaxed on this. But high fat intake after taking insulin can lead to high body fat.
    The carb/protein drink taken after the insulin shot should contain AT LEAST 10 grams of carbs and 5 grams of quality protein per IU of insulin injected with little or no fat(creatine taken in this drink is optional but works great). Before an hour passes you should eat a normal balanced meal(high protein low fat with carbs). At 2.5 hours after the injection you should Consume a small meal. keep some Gatorade on hand just to make sure. Remember that insulin can still work much later so be careful and eat if you feel hypoglycemia symptoms. Once again I've stated this twice because it is important.
    ***Some insulin users recommend far less carbs than I have stated above. This is a personal decision you will have to make since it could be very dangerous...Even deadly! My opinion is to take the carbs and learn to diet after bulking if you gain too much fat.***
    How long should/can I take insulin?
    Short cycles please because you could have side effects. It is suspected that you could become an insulin dependent diabetic but I have never seen proof, but is it worth the risk? I would only use it a few times a week(maximum 4 on 3 off) for no more than 3/4 weeks.
    What should I avoid while using insulin? Do not use alcohol. It lowers blood sugar, and you may experience dangerously low blood sugar levels
    Do not change your workout in the middle of a cycle of insulin. Changes in how much you exercise can change the amount of insulin you can tolerate and maintain blood sugar levels.
    Do not take any recreational drugs at the same time as insulin since they could mask symptoms of hypoglycemia.
    Do not change the brand of insulin or syringe that you are using without first talking to a doctor or pharmacist. Some brands of insulin and syringes are interchangeable, while others are not.
    Do not use insulin if you are sick with a cold, flu, or fever. These illnesses may change your insulin requirements..
    Do not use any insulin that is discolored, looks thick, has particles in it, or looks different from the way it looked when you bought it.
    Do not use OTC drugs that will cause drowsiness within 6 hours of using insulin.
    Do not go to sleep within 4/6 hours of using insulin since you can develop hypoglycemia while asleep and not have warning signs.
    What are the possible side effects of insulin besides hypoglycemia?
    Rarely, people have allergic reactions to insulin. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
    Hypothetically, one could become an insulin dependent diabetic if insulin is used too long
    If this were to happen..... then you almost deserve it for abusing slin....

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