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Lifestyle Interventions For Patients With And At Risk For Type 2 Diabetes

Lifestyle Interventions For Four Conditions: Type 2 Diabetes, Metabolic Syndrome, Breast Cancer, And Prostate Cancer

Lifestyle Interventions For Four Conditions: Type 2 Diabetes, Metabolic Syndrome, Breast Cancer, And Prostate Cancer

Lifestyle Interventions for Four Conditions: Type 2 Diabetes, Metabolic Syndrome, Breast Cancer, and Prostate Cancer Select the Print Complete Record, Add to Basket or Email Record Buttons to print the record, to add it to your basket or to email the record. Expand All All sections on the page are Expanded Collapse All All sections on the page are Collapsed Chronic diseases are the leading cause of death and disability worldwide. According to the World Health Organization, 88 percent of deaths in the United States in 2002 were attributable to chronic disease. Prevention of the onset or progression of chronic disease is often promoted as the gold standard, although the optimal interventions to achieve this have not been well documented. A number of lifestyle behaviors contribute to overall morbidity and mortality of chronic disease. Among these, physical activity and diet have been identified as two modifiable risk factors that may impact onset or progression of disease. Previous research has suggested that improved diet may decrease the burden of chronic disease, particularly coronary heart disease. However, the benefits of lifestyle modifications in preventing progression or recurrence of disease is not as well documented. In addition, it remains unclear how effective interventions are in modifying risk factors, and which chronic diseases, if any, would benefit. The chronic diseases examined in this review are type 2 diabetes, metabolic syndrome, breast and prostate cancer. Type 2 diabetes is a major cause of morbidity and mortality. Diabetes was the seventh leading cause of death in the U.S. in 2006; cardiovascular disease (CVD) accounted for more than 65 percent of all diabetic deaths. Diabetes is also the leading cause of kidney failure, nontraumatic lower-extremit Continue reading >>

Lifestyle Interventions Can Reduce Progression To Diabetes In At-risk Patients

Lifestyle Interventions Can Reduce Progression To Diabetes In At-risk Patients

Lifestyle Interventions Can Reduce Progression to Diabetes in At-risk Patients Comprehensive lifestyle interventions can reduce the incidence of type 2 diabetes(annals.org) in patients at increased risk for the disease, says a recent review and meta-analysis published in the Annals of Internal Medicine. The same types of interventions, however, do not appear to confer similar outcome benefits in those already diagnosed with type 2 diabetes. Avoiding Disease Progression in At-risk Patients According to data synthesized from nine randomized, controlled trials (RCTs) involving patients at risk for developing diabetes, interventions lasting six months or longer that included exercise, dietary changes and at least one other component, such as counseling or behavior modification, were effective in decreasing the incidence of progression to type 2 diabetes compared with usual care, a single-component intervention or assignment to a waiting list. At-risk patients were defined as those who had one or more of the following risk factors: Comprehensive lifestyle interventions can reduce the incidence of type 2 diabetes patients at increased risk for the disease, a new meta-analysis finds. The same types of interventions do not confer similar benefits in patients already diagnosed with the disease. Longer-term studies may provide greater insight into which combination of interventions produces the most benefit. Specifically, seven of the nine studies included in the analysis reported that comprehensive lifestyle interventions decreased diabetes risk from the end of the intervention to as long as 10 years afterward. Most of the studies also reported positive secondary outcomes, including beneficial changes in body composition, metabolic variables, physical activity levels and dietar Continue reading >>

Lifestyle Interventions Can Reduce Type 2 Diabetes Among High-risk Patients

Lifestyle Interventions Can Reduce Type 2 Diabetes Among High-risk Patients

Lifestyle interventions can reduce type 2 diabetes among high-risk patients 1. Based on this systematic review, the use of comprehensive lifestyle interventions significantly reduced the incidence of Type 2 diabetes mellitus (DM) among high-risk patients. 2. There is insufficient evidence to support the benefit of lifestyle interventions on cardiovascular or microvascular outcomes among patients with already established Type 2 DM. Study Rundown: Type 2 DM is an increasingly prevalent disease and a leading cause of death in the United States. This recent systematic meta-analysis assessed the impact of comprehensive lifestyle interventions in both patient populations at risk for Type 2 DM as well as patients with an already established diagnosis of Type 2 DM. In this study, two independent researchers selected 20 unique studies for analysis. The analysis found that among patients that are high risk, diet and exercise lifestyle interventions were associated with a statistically significant decrease in the development of Type 2 DM. However, there was not sufficient evidence to demonstrate benefit in cardiovascular outcome in this patient population. Among the patients with an established diagnosis of Type 2 DM, the analysis did not find evidence to support lifestyle interventions in improving all-cause mortality, cardiovascular outcomes and microvascular complications. Overall, this systematic analysis provided moderate evidence to support lifestyle intervention for prevention in type II DM in high risk patients, but its results did not suggest a benefit for its application in patients with an already established diagnosis of Type 2 DM. Relevant Reading: Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes In-Depth [systematic review]: Two independ Continue reading >>

Lifestyle Interventions To Prevent Type 2 Diabetes: A Systematic Review Of Economic Evaluation Studies

Lifestyle Interventions To Prevent Type 2 Diabetes: A Systematic Review Of Economic Evaluation Studies

Lifestyle Interventions to Prevent Type 2 Diabetes: A Systematic Review of Economic Evaluation Studies Koffi Alouki ,1 Hlne Delisle ,1 Clara Bermdez-Tamayo ,2and Mira Johri 3,4 1TRANSNUT, WHO Collaborating Centre on Nutrition Changes and Development, Department of Nutrition, Faculty of Medicine, University of Montreal, 2405 Chemin de la Cte Sainte-Catherine, Montreal, QC, Canada H3T 1A8 2Institut de Recherche en Sant Publique de lUniversit de Montral (IRSPUM), University of Montreal, 7101 Avenue du Parc, 3e tage, Montral, QC, Canada H3N 1X9 3Centre de Recherche du Centre Hospitalier de lUniversit de Montral (CRCHUM), Tour Saint-Antoine, 850 Rue Saint-Denis, Montral, QC, Canada H2X 0A9 4Department of Health Administration, School of Public Health (ESPUM), Faculty of Medicine, University of Montreal, 7101 Avenue du Parc, 3e tage, Montral, QC, Canada H3N 1X9 Received 17 July 2015; Revised 13 October 2015; Accepted 19 October 2015 Copyright 2016 Koffi Alouki et al. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To summarize key findings of economic evaluations of lifestyle interventions for the primary prevention of type 2 diabetes (T2D) in high-risk subjects. Methods. We conducted a systematic review of peer-reviewed original studies published since January 2009 in English, French, and Spanish. Eligible studies were identified through relevant databases including PubMed, Medline, National Health Services Economic Evaluation, CINHAL, EconLit, Web of sciences, EMBASE, and the Latin American and Caribbean Health Sciences Literature. Studies targeting obesity were also included. Data were extracted Continue reading >>

Diabetes Management: Intensive Lifestyle Interventions For Patients With Type 2 Diabetes

Diabetes Management: Intensive Lifestyle Interventions For Patients With Type 2 Diabetes

Diabetes Management: Intensive Lifestyle Interventions for Patients with Type 2 Diabetes The Community Preventive Services Task Force recommends intensive lifestyle interventions for patients with type 2 diabetes to improve glycemic (blood sugar) control and reduce risk factors for cardiovascular disease. The largest and longest trial to date provided intensive individual and group counseling and extended interpersonal support for dietary modification, regular physical activity, and weight management. Community Preventive Services Task Force. Diabetes Management: Intensive Lifestyle Interventions for Patients with Type 2 Diabetes [Internet]. 2016 Oct [cited 2017 March 6]. Available from: Effect Behavioral Change , Improve Quality of Life , Reduce Mortality , Health Care , Behavioral & Social , Patients The Healthy People 2020 evidence-based resources identified have been selected by subject matter experts at the U.S. Department of Health and Human Services. Each of the selected evidence-based resources has been rated and classified according to a set of specific criteria based, in part, on publication status, publication type, and number of studies. This classification scheme does no necessarily consider all dimensions of quality, such as statistical significance, effect size (e.g., magnitude of effect), meaningfulness of effect, additional effect over control, and study design (e.g., sample size, power, internal validity, external validity, generalizability, potential biases, potential confounders). Continue reading >>

Intensive Lifestyle Interventions Benefit Patients With Type 2 Diabetes

Intensive Lifestyle Interventions Benefit Patients With Type 2 Diabetes

Intensive lifestyle interventions benefit patients with type 2 diabetes Lifestyle interventions can have a number of positive effects in the management of type 2 diabetes. It has been well documented in two landmark clinical trials on the prevention of diabetes that dietary changes and regular physical activity will prevent or delay the development of diabetes in high-risk individuals. The Diabetes Prevention Project (DPP), a randomized controlled trial in patients with prediabetes, showed that 7% weight loss, achieved by a lifestyle modification program, reduced the 4-year cumulative incidence of diabetes by 58% vs. a placebo group that made no formal lifestyle changes. The program incorporated individual and group counseling sessions that encouraged a low-fat diet and at least 150 minutes of exercise (brisk walking) per week. The Finnish Diabetes Prevention Study extended the DPP by looking at the reduction in the incidence of diabetes in high-risk, middle-aged (mean age, 55 years) adults at as much as 5 years post-intervention. The intervention included personal counseling sessions aimed at moderate (5%) weight loss achieved by a low-fat, high-fiber diet and moderate exercise for about 30 minutes per day. The average weight loss at 5 years was only 4.6 lb, but resulted in a lower incidence of diabetes in this population (23%) vs. placebo (11%). Modest reductions in weight using a combination of dietary modifications and exercise resulted in significant reductions in the incidence of diabetes in high-risk individuals. A more recent analysis of the Action for Health in Diabetes (Look AHEAD) study by Gregg and colleagues examined the association of a long-term intensive weight-loss intervention with the frequency of remission of type 2 diabetes. This was a randomized c Continue reading >>

Lifestyle Intervention In Patients At Risk Of Type 2 Diabetes. The Effects Of Two Low-intensity Interventions, How Lifestyle Intervention Influences Health Related Quality Of Life And How The 13-item Sense Of Coherence Questionnaire Can Predict Successful Lifestyle Change

Lifestyle Intervention In Patients At Risk Of Type 2 Diabetes. The Effects Of Two Low-intensity Interventions, How Lifestyle Intervention Influences Health Related Quality Of Life And How The 13-item Sense Of Coherence Questionnaire Can Predict Successful Lifestyle Change

JavaScript is disabled for your browser. Some features of this site may not work without it. Lifestyle intervention in patients at risk of type 2 diabetes. The effects of two low-intensity interventions, how lifestyle intervention influences health related quality of life and how the 13-item Sense of Coherence questionnaire can predict successful lifestyle change Background: The global prevalence of type 2 diabetes (T2D) is rapidly increasing,linked to the epidemic of obesity and inactivity. There is substantial researchevidence for prevention of T2D by lifestyle interventions in high-risk individuals.Less comprehensive lifestyle interventions, or population-based strategies, are neededfor the more than half of Europeans at risk of T2D. Two low-intensity interventionsin adult Norwegians at risk of T2D were tested in a randomised, controlled design. Methods: Individuals at high risk of T2D were identified by general practitioners(GPs) using the seven-item Finnish Diabetes Risk Score (FINDRISC) and referredto the local hospital. A thorough first consultation with the study physician focusedon delivering a simple, clear and true message about the importance of theindividuals own efforts regarding both T2D and general health. Participants wererandomly assigned to an individual physician group (IG) or an individual plusinterdisciplinary group (IIG) for an 18-month follow-up. Participants in the IG andIIG groups consulted the study physician every six months. In addition, the IIG groupparticipated in an interdisciplinary group-based programme ( 10 participants, eighttimes (five hours per day)) over a period of three months. Outcome measures werechanges in lifestyle according to established goals that have been shown to reduceincidence of T2D and to improve health. Furthermor Continue reading >>

Lifestyle Interventions For Patients With And At Risk For Type 2 Diabetes: A Systematic Review And Meta-analysis.

Lifestyle Interventions For Patients With And At Risk For Type 2 Diabetes: A Systematic Review And Meta-analysis.

Ann Intern Med. 2013 Oct 15;159(8):543-51. doi: 10.7326/0003-4819-159-8-201310150-00007. Lifestyle interventions for patients with and at risk for type 2 diabetes: a systematic review and meta-analysis. The effect of multifaceted lifestyle interventions on clinically oriented outcomes across a spectrum of metabolic risk factors and abnormal glucose is unclear. To systematically review the effectiveness of lifestyle interventions on minimizing progression to diabetes in high-risk patients or progression to clinical outcomes (such as cardiovascular disease and death) in patients with type 2 diabetes. 5 electronic databases (1980 to June 2013), reference lists, and gray literature. Two reviewers independently identified randomized, controlled trials of lifestyle interventions (3 months' duration) that included exercise, diet, and at least 1 other component; the comparator was standard care. One reviewer extracted and a second verified data. Two reviewers independently assessed methodological quality. Nine randomized, controlled trials with patients who were at risk for diabetes and 11 with patients who had diabetes were included. Seven studies reported that lifestyle interventions decreased the risk for diabetes from the end of intervention up to 10 years after it. In patients with diabetes, 2 randomized, controlled trials (which included pharmacotherapy) reported no improvement in all-cause mortality (risk ratio, 0.75 [95% CI, 0.53 to 1.06]). Composite outcomes for cardiovascular disease were too heterogeneous to pool. One trial reported improvement in microvascular outcomes at 13-year follow-up. Most trials focused on surrogate measures (such as weight change, blood pressure, and lipids) for which clinical relevance was unclear. Comprehensive lifestyle interventions eff Continue reading >>

Effect Of Lifestyle Intervention In Patients With Type 2 Diabetes: A Meta-analysis

Effect Of Lifestyle Intervention In Patients With Type 2 Diabetes: A Meta-analysis

Abstract The effect of lifestyle intervention on clinical risk factors in patients with type 2 diabetes is unclear. The aim of this meta-analysis was to evaluate the effects of comprehensive lifestyle change, such as diet, exercise, and education, on clinical markers that are risk-factors for cardiovascular disease in patients with type 2 diabetes. We searched Medline, Cochrane, EMBASE, and Google Scholar (up to August 31, 2013) for randomized controlled trials that compared standard of care (control group) with treatment regimens that included changes in lifestyle (intervention group). The primary outcome was reduction in risk factors of cardiovascular disease including body mass index (BMI), glycated hemoglobin (HbA1c), systolic blood pressure (SBP), diastolic blood pressure (DBP), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c). A total of 16 studies were included in the meta-analysis. The standardized difference in means of change from baseline significantly favored the intervention compared with the control group in BMI (− 0.29; 95% CI, − 0.52 to − 0.06, P = 0.014), HbA1c (− 0.37; 95% CI, − 0.59 to − 0.14, P = 0.001), SBP (− 0.16: 95% CI, − 0.29 to − 0.03, P = 0.016), DBP (− 0.27, 95% CI = − 0.41 to − 0.12, P < 0.001). There was no difference between the intervention and control groups in HDL-c (0.05; 95% CI, − 0.10 to 0.21; P = 0.503) and LDL-c (− 0.14; 95% CI, − 0.29 to 0.02; P = 0.092). The meta-analysis found that lifestyle intervention showed significant benefit in risk factors that are known to be associated with development of cardiovascular disease in patients with type 2 diabetes. Fig. 1. Flow chart for study selection. Fig. 2. The quality assessment for each included study was sum Continue reading >>

Diabetes Management: Intensive Lifestyle Interventions For Patients With Type 2 Diabetes

Diabetes Management: Intensive Lifestyle Interventions For Patients With Type 2 Diabetes

The Community Preventive Services Task Force (CPSTF) recommends intensive lifestyle interventions for patients with type 2 diabetes to improve glycemic control and reduce risk factors for cardiovascular disease. Intervention Intensive lifestyle interventions provide ongoing counseling, coaching, or individualized guidance to patients with type 2 diabetes to help them change their diet, level of physical activity, or both. Patients must interact with program staff multiple times for a period of six months or longer. Dietary components may include tailored advice, and physical activity components may include structured and personalized guidance or supervised exercise training. Programs may have weight loss goals or include additional components related to weight loss or maintenance. The largest and longest trial to date provided intensive individual and group counseling and extended interpersonal support for dietary changes, regular physical activity, and weight management. Read the full CPSTF Finding and Rationale Statement [PDF - 603 kB] for details including implementation issues, possible added benefits, potential harms, and evidence gaps. This expedited finding was based on the following published systematic review: Huang XL, Pan JH, Chen D, Chen J, Hu TT. Efficacy of lifestyle interventions in patients with type 2 diabetes: A systematic review and meta-analysis. European Journal of Internal Medicine 2016;27;37-47. Promotional Materials Continue reading >>

Digital Lifestyle Intervention Platform Shown To Reduce Rates Of Type 2 Diabetes

Digital Lifestyle Intervention Platform Shown To Reduce Rates Of Type 2 Diabetes

Digital lifestyle intervention platform shown to reduce rates of Type 2 diabetes Liva Healthcare, a digital health platform designed to tackle chronic diseases, has released promising results on the effectiveness of digital interventions to help with weight loss and prevention of Type 2 diabetes . Liva Healthcare monitored the progress of 136 patients using its digital healthcare app to prevent and roll back Type 2 diabetes over a nine-month period. Over the period, 82% of the patients (112) lost weight, losing an average of 6.3kg and demonstrating signs of a successful lifestyle intervention. Encouragingly patients appear to be losing more weight, and faster, than previous studies with digital health interventions have shown. For instance, one study1 found patients to have a sustained weight loss of 7kg over 20 months though web-based interventions. A second study2 found patients with Type 2 diabetes lost 5.6kg over 12 months through web-based interventions, compared to a control group who received standard diabetes care and lost on average 2.8kg. If the patients using the Liva Healthcare platform continue on their current trajectory, the results will be evidence of the effectiveness of digital interventions. Through an app and desktop platform, Liva Healthcare provides a digital health coaching program for those with, and at risk of, chronic lifestyle diseases such as obesity and Type 2 diabetes. In addition to one-to-one goal setting and coaching, the platform provides self-monitoring health tools and online peer-to-peer support groups to assist patients in adopting and maintaining healthy lifestyle behaviors. Type 2 diabetes can be conquered with weight loss management The weight loss achieved by Liva Healthcares patients is promising for tackling obesity and the p Continue reading >>

Community-based Lifestyle Intervention Reduces Cardiovascular Disease Risk Factors In Type 2 Diabetes Patients

Community-based Lifestyle Intervention Reduces Cardiovascular Disease Risk Factors In Type 2 Diabetes Patients

Community-based Lifestyle Intervention Reduces Cardiovascular Disease Risk Factors in Type 2 Diabetes Patients The Journal of the American Osteopathic Association study finds two months of healthy living classes significantly reduced risk of common diabetes complications in Appalachia CHICAGO February 1, 2016 It took just 16 two-hour classes on the basics of a healthy lifestyle to substantially reduce cardiovascular risks associated with type 2 diabetes and elevated fasting blood glucose levels for 110 patients, according to a study published in The Journal of the American Osteopathic Association. The Complete Health Improvement Lifestyle Intervention Program (CHIP) includes dietary targets, cooking classes, an exercise program and group discussions to give participants the specifics they need to improve their health. Based on the fact that 75 percent or more of Western diseases are lifestyle-related, CHIP gives participants concrete instruction that takes a mind, body and spirit approach to healthy living. The retrospective study evaluated 2011-2014 data collected from 110 patients in six Ohio University CHIP cohorts from 11 Appalachian counties where the prevalence of diabetes is over 7 percent higher than the national average. Participants experienced significant reductions in total cholesterol levels (9.6 percent), fasting glucose (9 percent), body mass index (3.7 percent) and systolic blood pressure (5.7 percent). (See data table) Changes in Cardiovascular Disease Risk Factor Among Patients in CHIP Diabetes Values in parentheses indicate absolute mean changes from baseline. Data were not available for all participants. Abbreviations: BMI, body mass index; CHIP, Complete Health Improvement Program; DBP, diastolic blood pressure; FBG, fasting blood glucose; HDL-C, h Continue reading >>

Physical Exercise For The Prevention And Treatment Of Type 2 Diabetes - Em|consulte

Physical Exercise For The Prevention And Treatment Of Type 2 Diabetes - Em|consulte

Received:9June2010; accepted:14June2010 Physical exercise for the prevention and treatment of type 2 diabetes Exercice physique, prvention et traitement du diabte de type 2 , J.-F.Gautier d , e , f , H.Hanaire a , b aDepartment of Diabetology, Metabolic Diseases and Nutrition, CHU de Toulouse, 31073 Toulouse, France bUniversity Toulouse III, 31073 Toulouse, France cInserm unit U558, 37, alles Jules-Guesdes, 31073 Toulouse, France dDepartment of Diabetes and Endocrinology, hpital Saint-Louis, Assistance PubliqueHpitaux de Paris, Paris, France eUniversity Paris-Diderot Paris 7, Paris, France fUMR-S Inserm 872, centre de recherche des Cordeliers, University Pierre-et-Marie-Curie, Paris 6, Paris, France Corresponding author. Tel.: +33 5 61 32 26 85; fax: +33 5 61 32 31 23. The prevalence of type 2 diabetes is rapidly increasing worldwide, yet its primary prevention and treatment are still a challenge. The objectives of this review are to assess the effects of exercise on the prevention of type 2 diabetes in high-risk individuals and on glycaemic control in type 2 diabetic patients. Considering the available reports, there is unequivocal and strong evidence that physical exercise can prevent or delay progression to type 2 diabetes in subjects with impaired glucose tolerance. Also, lifestyle interventions, including diet and physical exercise, can result in a reduction of around 50% in diabetes incidence that persists even after the individual lifestyle counselling has stopped. In addition, short-term randomized studies have confirmed that physical training based on endurance and/or resistance exercises can also improve blood glucose control in type 2 diabetics with a mean glycated haemoglobin decrease of 0.6%. Thus, physical exercise should be part of any therapeutic strate Continue reading >>

Lifestyle Interventions In Patients With Or At Risk For Type 2 Diabetes

Lifestyle Interventions In Patients With Or At Risk For Type 2 Diabetes

Lifestyle Interventions in Patients with or at Risk for Type 2 Diabetes Jamaluddin Moloo, MD, MPH reviewing Schellenberg ES et al. Ann Intern Med 2013 Oct 15. In a meta-analysis, lifestyle interventions prevented diabetes, but evidence was insufficient to show benefit in patients with already-diagnosed diabetes. Dietary and exercise interventions are effective for preventing diabetes, but evidence is lacking on whether multifaceted lifestyle interventions benefit patients who already have diabetes or are at high risk for developing it. Researchers conducted a systematic review and meta-analysis of 20 randomized, controlled trials in which the effects of diet, exercise, and at least one other component (e.g., counseling, behavior modification, medication) were assessed in patients with diabetes or at high risk for diabetes. Control groups received usual care, educational materials, or various other interventions. Among high-risk patients, lifestyle interventions were associated significantly with lower risk for progression to diabetes for as long as 10 years after intervention (relative risk, 0.35); data on preventing adverse cardiovascular events and retinopathy were insufficient to evaluate those outcomes. Among patients with type 2 diabetes, lifestyle interventions were not associated with improvements in metabolic outcomes (e.g., blood pressure, lipids) after adjustment for medication use; evidence was insufficient on cardiovascular and microvascular outcomes, and all-cause mortality was similar between intervention and control groups during >10 years of follow-up. This meta-analysis showed that lifestyle interventions lowered risk for type 2 diabetes among people at high risk. Among patients already diagnosed with type 2 diabetes, findings were sobering: No reducti Continue reading >>

Lifestyle Interventions Can Reduce Type 2 Diabetes Risk

Lifestyle Interventions Can Reduce Type 2 Diabetes Risk

Lifestyle Interventions Can Reduce Type 2 Diabetes Risk Comprehensive lifestyle interventions may reduce the risk for type 2 diabetes in patients who are at high risk for the disease, but the interventions do not appear to reduce all-cause mortality in patients with the disease, according to a systematic literature review. Elizabeth Sumamo Schellenberg, BSc, MPH, and colleagues from the University of Alberta in Edmonton, Canada, present their findings in an article published in the October 15 issue of the Annals of Internal Medicine. "Many systematic reviews have reported a benefit with exercise and dietary interventions in diabetes prevention," the authors write. "However, we are not aware of any reviews that assessed the effect of multifaceted lifestyle interventions on clinically oriented outcomes across a spectrum of metabolic risk factors and abnormal glucose. Therefore, Dr. Schellenberg and colleagues searched 5 electronic databases (MEDLINE, Cochrane Central Register of Controlled Trials, CINAHL, EMBASE, and SCOPUS) to identify randomized controlled trials that evaluated the effects of multifaceted interventions (a exercise component, a diet component, and a third component) on the clinical outcomes of adult patients with type 2 diabetes or who were at high risk for the disease. They identified 9 studies of high-risk patients and 11 studies of patients with type 2 diabetes. For studies of high-risk patients, the duration of the intervention ranged from 6 to 72 months compared with 6 to 93 months for the studies of patients with type 2 diabetes. Among high-risk patients, the lifestyle intervention was associated with a reduced risk for type 2 diabetes (risk ratio [RR], 0.35; 95% confidence interval [CI], 0.14 - 0.85), and the efficacy of the intervention was main Continue reading >>

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