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So you’re standing in line at the checkout of your local pharmacy, your shopping basket filled with soap, shampoo, maybe a snack and some aspirin. But you know you forgot one thing — what was it? Oh yes, your diabetes medicine. No worries; it’s sitting right next to the cash register, strategically placed so that people like you remember to replenish their supply. Far-fetched? Not as much as you might think. According to an article published last week in the Washington Post, the US Food and Drug Administration (FDA) is considering allowing certain drugs for diabetes, asthma, and migraines to be sold without a prescription. No outcome is certain at this point, and the scenario described above might never come to pass even if the FDA’s plans proceed; pharmacists might be required to dispense a drug even if no doctor’s prescription is required. But if all goes as planned, the way people receive drugs used to treat some common health conditions could change dramatically. According to the Post article, the FDA is interested in increasing access to established drugs that have been shown to be easy to administer and relatively low-risk. Since over-the counter drugs require no visit to a doctor and tend to be cheaper than even generic prescription drugs, people with no health insurance or limited coverage could benefit from removing prescription requirements. On several past occasions, the FDA has granted petitions from drugmakers to allow a prescription drug to be sold over-the-counter. Examples from the last decade include omeprazole (brand name Prilosec and others), a drug for gastroesophageal reflux disease; and loratadine (Claritin and others), for allergies. The FDA envisions potential customers filling out questionnaires on electronic kiosks in pharmacies, poss Continue reading >>
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Metformin is a medicine used to treat type 2 diabetes and sometimes polycystic ovary syndrome (PCOS). Type 2 diabetes is an illness where the body doesn't make enough insulin, or the insulin that it makes doesn't work properly. This can cause high blood sugar levels (hyperglycemia). PCOS is a condition that affects how the ovaries work. Metformin lowers your blood sugar levels by improving the way your body handles insulin. It's usually prescribed for diabetes when diet and exercise alone have not been enough to control your blood sugar levels. For women with PCOS, metformin stimulates ovulation even if they don't have diabetes. It does this by lowering insulin and blood sugar levels. Metformin is available on prescription as tablets and as a liquid that you drink. Key facts Metformin works by reducing the amount of sugar your liver releases into your blood. It also makes your body respond better to insulin. Insulin is the hormone that controls the level of sugar in your blood. It's best to take metformin with a meal to reduce the side effects. The most common side effects are feeling sick, vomiting, diarrhoea, stomach ache and going off your food. Metformin does not cause weight gain (unlike some other diabetes medicines). Metformin may also be called by the brand names Bolamyn, Diagemet, Glucient, Glucophage, and Metabet. Who can and can't take metformin Metformin can be taken by adults. It can also be taken by children from 10 years of age on the advice of a doctor. Metformin isn't suitable for some people. Tell your doctor before starting the medicine if you: have had an allergic reaction to metformin or other medicines in the past have uncontrolled diabetes have liver or kidney problems have a severe infection are being treated for heart failure or you have recentl Continue reading >>
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When you think about diabetes drugs, you may think of insulin or other medications that you get from a shot or a pump. But there are others that you take as a pill or that you inhale. Your doctor will consider exactly what you need, which may include more than one type of diabetes medicine. The goal is to get your best blood sugar control, and the oral drugs do that in several ways. How it works: Blocks enzymes that help digest starches, slowing the rise in blood sugar. It belongs to a group of drugs called “alpha-glucosidase inhibitors.” Side effects for these kinds of drugs include stomach upset (gas, diarrhea, nausea, cramps). Alogliptin (Nesina) How it works: Boosts insulin levels when blood sugars are too high, and tells the liver to cut back on making sugars. Your doctor may call this type of drug a “DPP-IV inhibitor.” These drugs do not cause weight gain. You may take them alone or with another drug, like metformin. Bromocriptine mesylate (Cycloset, Parlodel) How it works: This tablet raises the level of dopamine, a brain chemical. It’s approved help improve blood sugar control in adults with type 2 diabetes, along with diet and exercise. It’s not used to treat type 1 diabetes. Canagliflozin (Invokana) How it works: Boosts how much glucose leaves your body in urine, and blocks your kidney from reabsorbing glucose. Your doctor may call this type of drug a “SGLT2 inhibitor.” Side effects can include: Urinary tract infections Dizziness, fainting Ketoacidosis or ketosis Increased risk of bone fracture Decreased bone mineral density Chlorpropamide (Diabinese) How it works: Lowers blood sugar by prompting the pancreas to release more insulin. Your doctor may call this type of drug “sulfonylureas.” This drug is not used as often as newer sulfonylurea Continue reading >>
Herbal Alternatives To Metformin
Metformin (Glucophage, Glumetza, Fortamet) is typically prescribed to counteract the effects of insulin resistance -- the body's sluggish response to the blood-sugar-lowering hormone insulin. Insulin resistance can lead to high blood sugars and may eventually progress to prediabetes or type 2 diabetes (T2DM). Metformin improves insulin sensitivity of the body tissues and reduces liver glucose production, both of which help lower blood sugar levels. The American Diabetes Association recommends metformin as a first-choice medicine to treat T2DM. It is also sometimes used in combination with exercise and weight loss in people with prediabetes. Some evidence suggests that a few herbs might mimic some of the effects of metformin. However, no herb is a proven alternative to metformin. Video of the Day Goat’s rue, or Galega officinalis, is an age-old remedy. In times past, it was used for assorted ailments, including diabetes. Metformin is a man-made chemical that's closely related to a substance found in goat’s rue. Animal studies from the 1970s and 1980s established that substances in goat's rue have blood-sugar-lowering effects. Some of these chemicals can be toxic, however, so human studies are lacking. A recent animal study was published in April 2008 in the "British Journal of Pharmacology." Researchers found that mice fed galegine -- a chemical found in goat's rue -- ate less, lost weight and had reduced blood sugar levels, compared to mice that weren't fed the chemical. Goat's rue is not approved for diabetes treatment by the U.S. Food and Drug Administration or Germany's Commission E, a scientific advisory board that reviews and approves herbal medicines. Commission E noted significant health risks with goat's rue and the availability of more effective diabetes tr Continue reading >>
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How does this medication work? What will it do for me? Metformin belongs to the class of medications called oral hypoglycemics, which are medications that lower blood sugar. It is used to control blood glucose (blood sugar) for people with type 2 diabetes. It is used when diet, exercise, and weight reduction have not been found to lower blood glucose well enough on their own. Metformin works by reducing the amount of glucose made by the liver and by making it easier for glucose to enter into the tissues of the body. Metformin has been found to be especially useful in delaying problems associated with diabetes for overweight people with diabetes. This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. How should I use this medication? The recommended starting dose of metformin extended release tablets for adults is 1,000 mg once daily, to be taken with food in the evening. The maximum daily dose should not exceed 2,000 mg once daily. Metformin may be used alone or with other medications that reduce blood sugar. To ens Continue reading >>
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Metformin is commonly prescribed for managing type 2 diabetes. To get metformin, you need to have a prescription written for you by your doctor. Looking for a medicine? Visit healthdirect’s list of medicines that contain metformin to find out more about a specific medicine. On this page you will find more information on what metformin is, what it’s used for, how it works, its risks and whether there are any other treatment options available in its place. What is metformin? Metformin hydrochloride is a diabetes medicine. What is metformin used for? Metformin is used to control blood glucose (sugar) levels in people who have type 2 diabetes. It can be prescribed for adults and children over the age of 10. Because metformin doesn’t cause weight gain and may help with weight loss, it is commonly prescribed for overweight people with type 2 diabetes. In adults, metformin can be used alone or together with other diabetes medicines, including insulin. How does metformin work? Metformin lowers blood glucose levels in two ways, by: reducing how much glucose is released from the liver, where it is stored helping the cells of your body to absorb more glucose from the bloodstream What forms of metformin are available? Metformin is available in different: packaging forms like tablets, extended release tables or combined with other diabetes medicines in the same tablet strengths. Risks and benefits of metformin Metformin reduces the complications caused by diabetes. Among its benefits are that it: doesn’t cause weight gain reduces bad cholesterol is very unlikely to cause abnormally low blood glucose levels (hypoglycaemia). Common gastrointestinal side effects of metformin include: diarrhoea nausea vomiting stomach upset, cramps and bloating. Each person responds to medicines Continue reading >>
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