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Is Humulin Nph?

Humulin N

Humulin N

HUMULIN® N (human insulin [rDNA origin]) isophane) Suspension DESCRIPTION HUMULIN N (human insulin [rDNA origin] isophane) suspension is a human insulin suspension. Human insulin is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. HUMULIN N is a suspension of crystals produced from combining human insulin and protamine sulfate under appropriate conditions for crystal formation. The amino acid sequence of HUMULIN N is identical to human insulin and has the empirical formula C257H383N65O77S6 with a molecular weight of 5808. HUMULIN N is a sterile white suspension. Each milliliter of HUMULIN N contains 100 units of insulin human, 0.35 mg of protamine sulfate, 16 mg of glycerin, 3.78 mg of dibasic sodium phosphate, 1.6 mg of metacresol, 0.65 mg of phenol, zinc oxide content adjusted to provide 0.025 mg zinc ion, and Water for Injection. The pH is 7.0 to 7.5. Sodium hydroxide and/or hydrochloric acid may be added during manufacture to adjust the pH. Continue reading >>

Humulin N (nph, Human Insulin Isophane (rdna Origin)) Dose, Indications, Adverse Effects, Interactions... From Pdr.net

Humulin N (nph, Human Insulin Isophane (rdna Origin)) Dose, Indications, Adverse Effects, Interactions... From Pdr.net

Intermediate-acting Human Insulins and Analogs Intermediate-acting insulin with a longer onset and duration of activity when compared to regular insulin; hormone secreted by pancreatic beta-cells of the islets of Langerhans essential for the metabolism and homeostasis of carbohydrate, fat, and protein; usually requires >= 2 injections/day when used as a basal insulin. Humulin N/Novolin N Subcutaneous Inj Susp: 1mL, 100U For the treatment of type 1 diabetes mellitus or for type 2 diabetes mellitus inadequately managed by diet, exercise, and oral hypoglycemics. NOTE: A consensus algorithm issued by the ADA and the European Association for the Study of Diabetes lists basal or intermediate-acting insulin as a second line or third line agent in patients with type 2 diabetes not controlled on oral drugs; metformin is the initial recommended therapy in all type 2 diabetics without contraindications. Once insulin is added, therapy can be intensified (e.g., addition of prandial insulin) to achieve optimal glycemic control. In patients who are receiving a sulfonylurea, the sulfonylurea should be discontinued when insulin therapy is initiated. The total daily dose is given as 1 to 2 injections per day, given 30 to 60 minutes before a meal or bedtime. Some patients may initially be given a single daily dose 30 to 60 minutes before breakfast, but 24-hour blood glucose control may not be possible with this regimen. Thus, a second injection given 30 to 60 minutes before dinner or bedtime may be required. When oral agents are used concomitantly in type 2 DM, a low initial dose of NPH insulin (e.g., 10 units) is often given in the evening. When used for intensive insulin therapy, NPH insulin is frequently mixed with a quick-acting insulin and given twice daily, although some patients w Continue reading >>

Nph Insulin

Nph Insulin

NPH insulin, also known as isophane insulin, is an intermediate–acting insulin given to help control blood sugar levels in people with diabetes.[3] It is used by injection under the skin once to twice a day.[1] Onset of effects is typically in 90 minutes and they last for 24 hours.[3] Versions are available that come premixed with a short–acting insulin, such as regular insulin.[2] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] NPH insulin is made by mixing regular insulin and protamine in exact proportions with zinc and phenol such that a neutral-pH is maintained and crystals form.[1] There are human and pig insulin based versions.[1] Protamine insulin was first created in 1936 and NPH insulin in 1946.[1] It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[4] The wholesale cost in the developing world is about 2.23 to 10.35 USD per 1,000 iu of NPH insulin.[5] In the United Kingdom 1,000 iu of NPH insulin costs the NHS 7.48 pounds while in the United States this amount costs about 134.00 USD.[2][6] Chemistry[edit] NPH insulin is cloudy and has an onset of 1–4 hours. Its peak is 6–10 hours and its duration is about 10–16 hours. History[edit] Hans Christian Hagedorn (1888–1971) and August Krogh (1874–1949) obtained the rights for insulin from Banting and Best in Toronto, Canada. In 1923 they formed Nordisk Insulin laboratorium, and in 1926 with August Kongsted he obtained a Danish Royal Charter as a non-profit foundation. In 1936, Hagedorn and B. Norman Jensen discovered that the effects of injecte Continue reading >>

Humulin N

Humulin N

What Is Humulin N? Humulin® N (NPH insulin) is a non-prescription form of insulin used to treat diabetes. It is an intermediate-acting insulin that starts working more slowly and lasts longer than regular insulin. Humulin N is not derived from animals. Instead, it is produced by combining a manufactured insulin (that is identical to human insulin) with certain chemicals to make it last longer. NPH stands for Neutral Protamine Hagedorn, so named because it has a neutral pH, contains protamine, and was invented by a scientist named Hans Christian Hagedorn. (Click Humulin N Uses for more information, including possible off-label uses.) Who Makes Humulin N? Humulin N is manufactured by Eli Lilly and Company. How Does It Work? Humulin N is a form of insulin, which is a hormone that is naturally produced by the pancreas. This hormone is important for several functions, such as controlling blood sugar. Insulin helps the cells of your body remove glucose ("sugar") from your bloodstream. This sugar fuels your body's cells, giving them the energy they need to work properly. You may need to take insulin if your pancreas has trouble making enough insulin, which is the case in people with type 1 diabetes and in some people who have type 2 diabetes. Normally, your body is able to maintain proper levels of sugar in your blood and inside your cells. However, in people with type 1 diabetes (and sometimes type 2 diabetes), the pancreas has trouble making insulin. This causes too much sugar to accumulate in the blood. Too much sugar can also accumulate in the blood if your body has trouble responding to normal levels of insulin, as is common in type 2 diabetes. Over time, high levels of sugar in the blood can lead to serious health problems in the eyes, feet, hands, kidneys, and heart. H Continue reading >>

Humulin N Kwikpen Interactions

Humulin N Kwikpen Interactions

What Is Humulin N Kwikpen? Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin isophane is an intermediate-acting insulin that starts to work within 2 to 4 hours after injection, peaks in 4 to 12 hours, and keeps working for 12 to 18 hours. Insulin isophane is used to improve blood sugar control in adults and children with diabetes mellitus. Insulin isophane may also be used for purposes not listed in this medication guide. Never share an injection pen or syringe with another person, even if the needle has been changed. You should not use insulin isophane if you are allergic to it, or if you are having an episode of hypoglycemia (low blood sugar). Do not give insulin isophane to a child without a doctor's advice. To make sure this medicine is safe for you, tell your doctor if you have: liver or kidney disease; or low levels of potassium in your blood (hypokalemia). Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems. Follow your doctor's instructions about using insulin if you are pregnant or breast-feeding a baby. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Your dose needs may also be different while you are breast-feeding. Humulin N Kwikpen Side Effects Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat. Call your doctor at once if you have: fluid Continue reading >>

Humulin N

Humulin N

Brand Names: Humulin N, Humulin N Pen, Novolin N, Novolin N Innolet, Novolin N PenFill, Relion Novolin N Generic Name: insulin isophane (Pronunciation: IN soo lin EYE soe fane) What is insulin isophane (Humulin N, Humulin N Pen, Novolin N, Novolin N Innolet, Novolin N PenFill, Relion Novolin N)? Insulin isophane is a man-made form of a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin isophane is a long-acting form of insulin that is slightly different from other forms of insulin that are not man-made. Insulin isophane is used to treat diabetes. Insulin isophane may also be used for other purposes not listed in this medication guide. What are the possible side effects of insulin isophane? Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out. Hypoglycemia, or low blood sugar, is the most common side effect of insulin isophane. Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, or seizure (convulsions). Watch for signs of low blood sugar. Carry a piece of non-dietetic hard candy or glucose tablets with you in case you have low blood sugar. Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin isophane. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about insulin isophane? Take care to Continue reading >>

Humulin N Vs. Novolin N: A Side-by-side Comparison

Humulin N Vs. Novolin N: A Side-by-side Comparison

Diabetes is a disease that causes high blood sugar levels. Not treating your high blood sugar levels can damage your heart and blood vessels. It can also lead to stroke, kidney failure, and blindness. Humulin N and Novolin N are both injectable drugs that treat diabetes by lowering your blood sugar levels. Humulin N and Novolin N are two brands of the same kind of insulin. Insulin lowers your blood sugar levels by sending messages to your muscle and fat cells to use sugar from your blood. It also tells your liver to stop making sugar. We’ll help you compare and contrast these drugs to help you decide if one is a better choice for you. Humulin N and Novolin N are both brand names for the same drug, called insulin NPH. Insulin NPH is an intermediate-acting insulin. Intermediate-acting insulin lasts longer in your body than natural insulin does. Both drugs come in a vial as a solution that you inject with a syringe. Humulin N also comes as a solution you inject with a device called a KwikPen. You do not need a prescription to buy Novolin N or Humulin N from the pharmacy. However, you do need to talk to your doctor before you start using it. Only your doctor knows whether this insulin is right for you and how much you need to use. The table below compares more drug features of Humulin N and Novolin N. Humulin N Novolin N What drug is it? Insulin NPH Insulin NPH Why is it used? To control blood sugar in people with diabetes To control blood sugar in people with diabetes Do I need a prescription to buy this drug? No* No* Is a generic version available? No No What forms does it come in? Injectable solution, available in a vial that you use with a syringe Injectable solution, available in a cartridge that you use in a device called a KwikPen Injectable solution, available in Continue reading >>

Humulin N

Humulin N

Generic Name: insulin isophane (IN soo lin EYE soe fane) Brand Names: HumuLIN N, HumuLIN N KwikPen, NovoLIN N, Relion NovoLIN N What is Humulin N? Humulin N (insulin isophane) is a man-made form of a hormone that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin isophane is an intermediate-acting insulin that starts to work within 2 to 4 hours after injection, peaks in 4 to 12 hours, and keeps working for 12 to 18 hours. Humulin N is used to improve blood sugar control in adults and children with diabetes mellitus. Humulin N may also be used for purposes not listed in this medication guide. Important information Do not use Humulin N if you are having an episode of hypoglycemia (low blood sugar). Never share an injection pen or syringe with another person, even if the needle has been changed. Hypoglycemia, or low blood sugar, is the most common side effect of Humulin N. Symptoms of low blood sugar may include headache, hunger, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Watch for signs of low blood sugar. Carry a piece of non-dietetic hard candy or glucose tablets with you in case you have low blood sugar. Before taking this medicine You should not use Humulin N if you are allergic to insulin isophane, or if you are having an episode of hypoglycemia (low blood sugar). Do not give Humulin N to a child without a doctor's advice. To make sure Humulin N is safe for you, tell your doctor if you have: liver or kidney disease; or low levels of potassium in your blood (hypokalemia). Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using Continue reading >>

Humulin N (insulin Isophane Aka Insulin Nph)

Humulin N (insulin Isophane Aka Insulin Nph)

Humulin N is one brand of the man-made form of insulin known as insulin NPH or insulin isophane. It is produced by Eli Lilly and Company using recombinant DNA technology from a non-pathological strain of E. coli. It combines human insulin with protamine sulfate to create a crystalline suspension. Humulin N is used to help lower blood glucose levels in people with diabetes. Humulin N is one of the few insulins available without a prescription in some states (although you must ask for it at the pharmacy counter, since it has to stay refrigerated). How Does Humulin N Work? Humulin N is an intermediate-acting insulin, which begins to take effect between one and four hours after injection. Its peak effect occurs four to 12 hours after injection and keeps working for 12 to 18 hours after injection. For some people, it can take 24 hours to clear out of their system. Humulin N acts like your body’s natural insulin to lower or normalize your blood sugar levels. It is often used in conjunction with a short-acting insulin and/or other oral anti-diabetic medications (such as Metformin). This insulin can also be mixed with certain other insulins, such as regular insulin. Consult with your doctor on whether mixing insulins is right for you. They can also instruct you on the correct way to do so. Humulin N can be used to improve glycemic control in adults and children with diabetes. Who Should Not Take Humulin N? Do not take Humulin N if you are experiencing hypoglycemia (low blood sugar). Do not take Humulin N if you are allergic to insulin isophane or any of its ingredients: dibasic sodium phosphate, glycerol, m-cresol, phenol, protamine sulfate, and zinc. It may also contain dimethicone, hydrochloric acid, and sodium hydroxide. If your doctor prescribes Humulin N, you will inject Continue reading >>

Brand Name: Humulin Nph Isophane

Brand Name: Humulin Nph Isophane

Humulin NPH Isophane is a medicine containing the active ingredient(s) insulin isophane human. On this page you will find out more about Humulin NPH Isophane, including side effects, age restrictions, food interactions and whether the medicine is subsidised by the government on the pharmaceutical benefits scheme (PBS) You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. Always read the label. If symptoms persist see your healthcare professional. healthdirect medicines information is not intended for use in an emergency. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance. Reasonable care has been taken to provide accurate information at the time of creation. This information is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to manage or diagnose a medical condition. Please refer to our terms and conditions. Continue reading >>

Humulin N Nph U-100 Insulin (isophane Susp) Subcutaneous : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - Webmd

Humulin N Nph U-100 Insulin (isophane Susp) Subcutaneous : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - Webmd

Insulin isophane is used with a proper diet and exercise program to control high blood sugar in people with diabetes . Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke . This man-made insulin product is the same as human insulin . It replaces the insulin that your body would normally make. It is an intermediate-acting insulin (isophane). It starts to work more slowly but lasts longer than regular insulin. Insulin isophane works by helping blood sugar ( glucose ) get into cells so your body can use it for energy. Insulin isophane is often used in combination with a shorter-acting insulin. It may also be used alone or with other oral diabetes drugs (such as metformin ). Read the Patient Information Leaflet provided by your pharmacist before you start using insulin isophane and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist. Learn all preparation and usage instructions from your health care professional and the product package. Before using, gently roll the vial or cartridge, turning it upside down and right side up 10 times to mix the medication . Do not shake the container. Check this product visually for particles or discoloration. If either is present, do not use the insulin . Insulin isophane should look evenly cloudy/milky after mixing. Do not use if you see clumps of white material, a "frosty" appearance, or particles stuck to the sides of the vial or cartridge. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin and to avoid developing problems under the skin Continue reading >>

Humulin-n

Humulin-n

How does this medication work? What will it do for me? Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels. There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. NPH is an intermediate-acting insulin. It takes 1 to 3 hours to begin working after injection, reaches its maximum effect between 5 and 8 hours, and stops working after about 18 to 24 hours. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it. What form(s) does this medication come in? Vial Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, glycerol, m-cresol, phenol, protamine sulfate, and zinc. May contain dimethicone, hydrochloric acid, and sodium hydroxide. Cartridge/KwikPen Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, Continue reading >>

Humulin Nph (cartridge) Suspension For Injection

Humulin Nph (cartridge) Suspension For Injection

Consumer medicine information (CMI) leaflet Please read this leaflet carefully before you start using Humulin NPH (Cartridge) Suspension for injection. Download CMI (PDF) Download large text CMI (PDF) What is in this leaflet This leaflet answers some common questions about HUMULIN. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMULIN and its use that you should be aware of. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HUMULIN against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Keep this leaflet with this medicine. You may need to read it again. What HUMULIN is used for HUMULIN is used to reduce high blood sugar (glucose) levels in patients with diabetes mellitus. Diabetes is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. There are two types of diabetes mellitus: Type 1 diabetes - also called juvenile onset diabetes. Type 2 diabetes - also called maturity onset diabetes. Patients with type 1 diabetes always require insulin to control their blood sugar levels. Some patients with type 2 diabetes may also require insulin after initial treatment with diet, exercise and tablets. HUMULIN is identical t Continue reading >>

Humulin Nph (vial) Suspension For Injection

Humulin Nph (vial) Suspension For Injection

Consumer medicine information (CMI) leaflet Please read this leaflet carefully before you start using Humulin NPH (Vial) Suspension for injection. Download CMI (PDF) Download large text CMI (PDF) What is in this leaflet This leaflet answers some common questions about HUMULIN. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMULIN and its use that you should be aware of. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HUMULIN against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Keep this leaflet with this medicine. You may need to read it again. What HUMULIN is used for HUMULIN is used to reduce high blood sugar (glucose) levels in patients with diabetes mellitus. Diabetes mellitus is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. There are two types of diabetes mellitus: Type 1 diabetes - also called juvenile onset diabetes. Type 2 diabetes - also called maturity onset diabetes. Patients with type 1 diabetes always require insulin to control their blood sugar levels. Some patients with type 2 diabetes may also require insulin after initial treatment with diet, exercise and tablets. HUMULIN is identic Continue reading >>

Humulin-n

Humulin-n

How does this medication work? What will it do for me? Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels. There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. NPH is an intermediate-acting insulin. It takes 1 to 3 hours to begin working after injection, reaches its maximum effect between 5 and 8 hours, and stops working after about 18 to 24 hours. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it. What form(s) does this medication come in? Vial Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, glycerol, m-cresol, phenol, protamine sulfate, and zinc. May contain dimethicone, hydrochloric acid, and sodium hydroxide. Cartridge/KwikPen Each mL contains 100 units of NPH insulin. Nonmedicinal ingredients: dibasic sodium phosphate, Continue reading >>

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