Compare Human Insulin Vs. Humalog
Some types of this medication are available without a prescription. Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose. Available in different combinations so that you can do one shot or multiple shots a day. Humalog (insulin lispro) is the most effective medication for lowering your blood sugar. Humalog (insulin lispro) can be used even if you have liver or kidney problems, unlike other anti-diabetic medications. 57 reviews so far Have you used Humulin (Human Insulin)? Leave a review 280 reviews so far Have you used Humalog (insulin lispro)? Leave a review Continue reading >>
Indication For Humulin R U-500
If your A1C is uncontrolled on high doses of standard insulin—more than 200 units a day—you may have another diabetes treatment option. Humulin® R U-500 is 5x concentrated insulin* available in a U-500 KwikPen® or syringe and vial. U-500 lowered high blood sugar in a clinical study. † If your doctor has prescribed U-500 for you or a loved one, learn more here. † 24 week, open-label, randomized trial to compare the efficacy and safety of 2 dosing regiments (TID, n=162 vs BID, n=163) for U-500 insulin replacing high dose U-100 insulin (>200 units per day) with or without oral antihyperglycemic drugs in adult patients with uncontrolled type 2 diabetes. These regimens were found to be equivalent for A1C reduction over 24 weeks, and both were efficacious. Study conducted with U-100 insulin syringes and Humulin R U-500 vials. Continue reading >>
Phase Ii Pharmacokinetics Study Of Humalog And Humulin-r With And Without Rhuph20 In Type 1 Diabetes Mellitus
You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. ClinicalTrials.gov Identifier: NCT00774800 Information provided by (Responsible Party): Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information Humalog and Humulin-R (recombinant human insulin) are Food and Drug Administration (FDA) approved medications for the treatment of diabetes mellitus. Recombinant human hyaluronidase PH20 (rHuPH20) is approved by the FDA for use as an aid in the absorption and dispersion of other injectable drugs. In this study, rHuPH20 will be co-administered with both Humalog and Humulin-R in order to determine if it improves the absorption of these insulins to more closely mimic the body's natural increase in insulin in response to a meal. Drug: Humalog Drug: Humulin-R Drug: Recombinant human hyaluronidase PH20 (rHuPH20) Other: Liquid meal Participants received all 4 interventions in the same order. Dose-finding visits were conducted to identify the appropriate dose of Humalog and Humulin-R. For each Humalog dose-finding visit, a total of 24 U of rHuPH20 was injected SC per unit of Humalog, corresponding to a mass concentration of 18.2 micrograms per milliliter (g/mL) rHuPH20 (at final concentration of 91 U/mL of Humalog). For each Humulin-R dose-finding visit, a total of 24 U of rHuPH20 was injected SC per unit of Humulin-R Continue reading >>
Insulin Lispro: A Fast-acting Insulin Analog
Research has established the importance of maintaining blood glucose levels near normal in patients with type 1 (insulin-dependent) diabetes mellitus. Short-acting insulin analogs are designed to overcome the limitations of regular short-acting insulins. Compared with regular human insulin, the analog insulin lispro offers faster subcutaneous absorption, an earlier and greater insulin peak and a more rapid post-peak decrease. Insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, and peak levels occur 30 to 90 minutes after administration. Duration of activity is less than five hours. Rates of insulin allergy, lipodystrophy, hypoglycemia and abnormal laboratory test results are essentially the same in patients using insulin lispro and in those using regular human insulin. The Diabetes Control and Complications Trial (DCCT)1 established the importance of maintaining near-normal blood glucose levels in patients with type 1 (insulin-dependent) diabetes mellitus. In these patients, intensive therapeutic regimens have been found to delay the onset and reduce the progression of microvascular complications by 50 to 75 percent as compared with conventional regimens. Although no large-scale investigations have been completed, smaller studies have reported similar benefits for intensive therapeutic regimens in patients with type 2 (non–insulin-dependent) diabetes.2 Primary care physicians provide medical care for 75 percent of children and 90 to 95 percent of adults with diabetes.3 Regardless of the type of diabetes, improved glycemic control often can be achieved with individualized tools for patient self-management, carefully formulated nutrition plans and the use of alternative insulin regimens.4 Overview of Insulin Insulin is necessary Continue reading >>
What Is The Difference Between Humalog Vs Humulin?
Humalog and Humulin refer to insulin medications that are used to reduce high blood sugar in people with diabetes. Insulin is a naturally occurring hormone that is produced by the beta cells in the pancreas. This hormone helps glucose (sugar) convert into energy for the cells in your body. Without insulin, glucose will not convert into energy, causing a build up of sugar in the blood and a lack of energy for the body. Too much glucose in the blood can lead to serious health problems, such as blindness, kidney failure and damage to blood vessels. Both medications can be used to control high blood sugar in people with diabetes. Humalog and Humulin may have similar drug interactions when used together with other medications. Sometimes these drug interactions can lead to harmful effects, such as low blood sugar, which is why you should inform your doctor about all medications you are using. Both drugs are injected under the skin to help reduce high blood sugar levels in people with diabetes. However, Humalog starts to work faster compared to Humulin. When you inject Humalog, it starts to work between 30 to 90 minutes. However, Humulin is most effective 3 hours after injecting it. What is Humalog? It is a rapid acting insulin analog that acts by improving glycemic control in people with type 2 diabetes. You should administer this medication within 15 minutes before your meal or immediately after you eat. What is Humulin? It is a man made form of the natural insulin produced by the pancreas. This insulin is used by people with type 2 diabetes to help improve their blood glucose levels in a similar way to how insulin works in people without diabetes. Humalog vs Humulin: The Side Effects There are some side effects that are common in both Humalog and Humulin. The most common ar Continue reading >>
Humalog Vs. Novolog: What’s The Difference?
The two leaders in the fast acting insulin market, Humalog and Novolog, are the most common types of fast acting insulin used by those with diabetes today. Fast Acting, mealtime insulin is a type of insulin that is injected before or right after eating. When you eat your blood glucose begins to rise. Fast acting insulin, Humalog and Novolog work to help manage these rises or spikes to keep your blood glucose levels more within range and balanced. When you use a fast acting insulin like Humalog or Novolog, you typically will continue to take a long acting insulin to help manage your levels between your meals and throughout the night. The question is though, is there really a difference between the two? Endocrinologists and other medical professionals don’t seem to really think there is, stating the two are virtually interchangeable. But that’s not really the full story. Humalog (Insulin Lispro) Insulin Lispro (Humalog) has been on the market since 1996, when it was first introduced by Eli Lily. Humalog is the first insulin analogue that was used clinically. Insulin Lispro received its name due to its structure. The difference between it and regular insulin was the switch between the lysine B28 (an amino acid) and proline B29. The formula consists of a hexametric solution available in vials and pen form. After a subcutaneous injection, the formula converts into a monomeric formula which allows it to have a fast absorption in the body. The one noted negative factor of Humalog is its short term control of glucose levels. Additionally, if it is injected and mealtime happens to be delayed, a hypoglycemic episode may occur. For Humalog to be most effective it is to be injected 15 minutes prior to the start of a meal. I recommend reading the following articles: Humalog is a Continue reading >>
Humalog, Humulin And Human Error
The use of Humalog with Eli Lillys Humulin has created some confusion especially among the elderly over the similarities in appearance between the two insulins. According to a recent newsletter titled Insulin Oversight, published by the United States Pharmacopeial Convention (USP), a federally funded FDA program, mix-ups over Humalog and Humulin have become common. The two names may seem a world apart to some, but to many there are enough similarities to cause problems. Both begin with h-u-m, have three syllables and contain the letter l in the third syllable. In addition, the products are available in 10 ml vials that are the same size and shape, their labels carry identical logos, and the label information is printed in the same style and color. When notified of the insulin mix-ups, Eli Lilly representative, Laura Stallman commented, customer services has received some calls, however a review of our safety database did not reveal any reports of adverse events related to the mix-ups. However, Stallman says that Eli Lilly is working with the FDA to make insulin bottle changes in order to help older patients and the visually impaired. These changes will not be phased in until sometime in 1998. In the meantime, the USP recommends these helpful hints to avoid insulin error: Make sure you use the proper insulin syringes to measure your doses. Make sure you can read the calibrated markings on the insulin syringes. Be sure that you understand your insulin regimen keep a written copy of your regimen with you at all times. Store various insulin preparations in separate sections of the refrigerator. This will reduce the risk of taking the wrong one. Remember that Humalog is a clear solution, while the longer acting insulins (except Regular) are cloudy. Be aware of the different Continue reading >>
- Cannibals Arrested In Florida Claim Eating Human Flesh Cures Diabetes and Depression
- The gut microbiome as a target for prevention and treatment of hyperglycaemia in type 2 diabetes: from current human evidence to future possibilities
- Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes
Patient Preference And Willingness-to-pay For Humalog Mix25 Relative To Humulin 30/70: A Multicountry Application Of A Discrete Choice Experiment
Volume 7, Issue 4 , JulyAugust 2004, Pages 442-454 Patient Preference and Willingness-to-Pay for Humalog Mix25 Relative to Humulin 30/70: A Multicountry Application of a Discrete Choice Experiment Author links open overlay panel MichaelAristidesMSca To assess preference and willingness-to-pay (WTP) for the insulin mixture Humalog Mix25 relative to Humulin 30/70, from the patients' perspective, the relative importance of individual treatment attributes was also determined. Differences among five European countries were investigated. Two hundred and ninety patients with type 2 diabetes were recruited from five European countries. Of these, 235 were suitable for inclusion in the analysis. Their mean age was 51.3 years and, on average, patients had had diabetes for 11 years. A discrete-choice conjoint analysis was conducted using face-to-face interviews. Treatment attributes, such as timing of injections around meals, 2-hour postprandial control, effect of prandial dosing, frequency of nocturnal hypoglycemia, and cost, and levels were derived after a systematic review of all published comparative clinical trial data. Meta-analyses were undertaken where appropriate. Ninety percent (95% CI 8693%) of patients would choose Humalog Mix25 over Humulin 30/70, at the same cost. On average, European subjects were willing to pay 111 per month more for Humalog Mix25 (95% CI 86.71156.91). The primary driver was the reduced risk of nocturnal hypoglycemic events, contributing 49% of WTP. The convenience of dosing immediately before the meal contributed 37%. Preference results were similar in all five countries, although WTP and sensitivity to increasing cost both varied. Patients in all countries showed a preference and WTP for Humalog Mix25 over Humulin 30/70. The main drivers of patie Continue reading >>
- Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes
- Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE)
- Diabetes Diet: Why Limiting Processed Foods Is A Healthy Choice
Brand Names: Humulin R, Novolin R, Novolin R Innolet, Novolin R Penfill, Relion/novolin R
A A A Medications and Drugs Generic Name: insulin regular (Pronunciation: IN soo lin REG yoo lar) What is insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What are the possible side effects of insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What is the most important information I should know about insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What should I discuss with my healthcare provider before using insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? How should I use insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What happens if I miss a dose (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What happens if I overdose (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What should I avoid while using insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What other drugs will affect insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What is insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin regular is a short-acting form of insulin. Insulin regular is used to treat diabetes. Insulin regular may also be used for other purposes not listed in this medication guide. What are the possible side effects of insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? Get emergency medical help if you Continue reading >>
What Is The Difference Between Humulin N And Humalog R?
A: In the words of your question, you illustrate the problem with the names of different types of insulin. There is no such thing as “Humalog R,” It’s not your fault; the names are confusing. Humulin is a brand of insulin. It does not tell you the type of insulin. It tells you that the insulin was made by Eli Lilly and Company. Humalog is rapid-acting insulin made by the same company. Similarly, Novolin is the brand name used for insulin made by Novo Nordisk. Novolog is the rapid-acting insulin made by this company. There is one other rapid-acting insulin – Apidra. Fortunately this one has no sound-alike. Continue reading >>
Dropped By Insurance: Will Your Diabetes Injectables Be Covered In 2014?
Express Scripts and Caremark have removed certain medications from their formulary starting in January 2014. These companies handle prescription benefits for more than 200 million Americans, so your prescription coverage will likely be changing in the new year. We’re reviewing which prescriptions will no longer be covered and the suggested alternatives to give you a better picture of your options. There have been some big changes to the coverage on diabetes meds removed from each formulary, particularly when it comes to insulin: Caremark Removed medications: Humalog and Humulin insulins || Suggested Alternatives: Apidra, Novolog, or Novolin insulins The Caremark exclusions here include Humalog, Humalog 50/50, Humalog 75/25, Humulin N, Humulin R, and Humulin 70/30 (but not Humulin U-500). I see more patients on Humalog than Novolog, however, both work on the body the same way, either rapid acting or a combination of rapid/intermediate acting. The main concern patients may have is “will my dose be the same?” The answer to that question is YES—the conversion from Humalog to Novolog and Humulin to Novolin is a 1:1 conversion. Therefore, if you using 10 units of Humalog you will also use 10 units of Novolog and the same applies for Humulin and Novolin. Apidra conversion is also 1:1, so once again your insulin dose will not change. These links from Group Health Cooperative and The Pharmacist Letter (via Albany.edu) will be very helpful for any questions about conversion: Part 1 and Part 2 Novolog and Apidra also have manufacturer discounts available—you can find the Novolog program here and the Apidra program here. Express Scripts Removed medications: Victoza || Suggested Alternatives: Byetta or Bydureon Victoza has been gaining a lot of popularity in the diabetic c Continue reading >>
Combination Insulins
Rapid-Acting Analogues Short-Acting Insulins Intermediate-Acting Insulins Long-Acting Insulins Combination Insulins Novolin® 70/30 - Humulin® 70/30 Novolog® Mix 70/30 Humalog® Mix 75/25 SOLIQUA™ 100/33 (insulin glargine and lixisenatide injection) XULTOPHY® 100/3.6 (insulin degludec and liraglutide injection) --® Onset: 30-60 min Peak: 2-12 hours Duration: 18 - 24 hours Solution: Cloudy Comments: Mixture of 70% NPH, Human Insulin Isophane Suspension and 30% Regular, Human Insulin Injection. Recommended interval between dosing and meal initiation: 30 minutes. Mixing You should not attempt to change the ratio of this product by adding additional NPH or Regular insulin to the vial. If the physician has prescribed insulin mixed in a proportion other than 70% NPH and 30% Regular, you should use the separate insulin formulations (e.g. NPH and Regular insulin ) in the amounts recommended by the physician. All Unopened Novolin 70/30: • Keep all unopened Novolin 70/30 in the refrigerator between 36° to 46°F (2° to 8°C). • Do not freeze. Do not use Novolin 70/30 if it has been frozen. • If refrigeration is not possible, the unopened vial may be kept at room temperature for up to 6 weeks (42 days), as long as it is kept at or below 77°F (25°C). • Keep unopened Novolin 70/30 in the carton to protect from light. Novolin 70/30 in use: Vials • Keep at room temperature below 77°F (25°C) for up to 6 weeks (42 days). • Keep vials away from direct heat or light. • Throw away an opened vial after 6 weeks (42 days) of use, even if there is insulin left in the vial. • Unopened vials can be used until the expiration date on the Novolin 70/30 label, if the medicine has been stored in a refrigerator. Note: double mouse click to return to the top of the page Onset Continue reading >>
Biod-531 Vs. Humalog Mix 75/25 Vs. Humulin R U-500 Post-meal Glucose Control In Patients With Severe Insulin Resistance
The study is designed to compare meal time glucose control associated with BIOD-531, a rapidly absorbed concentrated insulin to that associated with Humalog Mix 75/25 and Humulin R U-500 in patients with diabetes and severe insulin resistance. Study Type : Interventional (Clinical Trial) Actual Enrollment : 12 participants Allocation: Randomized Intervention Model: Crossover Assignment Masking: Single (Participant) Primary Purpose: Treatment Official Title: A Single-blind Crossover Study of the Pharmacokinetic and Postprandial Glucose Dynamics of BIOD-531 Compared to Humulin® R U-500 and Humalog® Mix75/25™ in Subjects With Type 2 DM Who Are Treated With ≥ 150 Units of Insulin Per Day Study Start Date : May 2014 Primary Completion Date : November 2014 Arm Intervention/treatment Experimental: BIOD-531 pre-meal Subcutaneous injections of 1.2 U/kg before the start of a standardized breakfast and 0.8 U/kg before the start of a standardized dinner. Drug: BIOD-531 Active Comparator: Humalog Mix 75/25 pre-meal Subcutaneous injections of 1.2 U/kg before the start of a standardized breakfast and 0.8 U/kg before the start of a standardized dinner. Drug: Humalog Mix 75/25 Active Comparator: Humulin R U-500 pre-meal Subcutaneous injections of 1.2 U/kg before the start of a standardized breakfast and 0.8 U/kg before the start of a standardized dinner. Drug: Humulin R U-500 Experimental: BIOD-531 post-meal Subcutaneous injections of 1.2 U/kg 20 minutes after the start of a standardized breakfast and 0.8 U/kg 20 minutes after the start of a standardized dinner. Drug: BIOD-531 Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To Continue reading >>
Insulin For Type 1 And Type 2 Diabetes
The different types of insulin are categorized according to how fast they start to work (onset) and how long they continue to work (duration). The types now available include rapid-, short-, intermediate-, and long-acting insulin. Injectable insulin is packaged in small glass vials (bottles) and cartridges that hold more than one dose and are sealed with rubber lids. The cartridges are used in pen-shaped devices called insulin pens. Insulin usually is given as an injection into the tissues under the skin (subcutaneous). It can also be given through an insulin pump , an insulin pen , or jet injector, a device that sprays the medicine into the skin. Some insulins can be given through a vein (only in a hospital). Research is ongoing to develop not only new forms of insulin but also insulin that can be taken in other ways, such as by mouth. Insulin lets sugar (glucose) in the blood enter cells, where it is used for energy. Without insulin, the blood sugar level rises above what is safe for the body. If the cells don't get sugar to use for energy, they try to use other nutrients in the body. When this happens, acids can build up. Too much acid production (ketoacidosis) can be serious or even life-threatening. Your body uses insulin in different ways. Sometimes you need insulin to work quickly to reduce blood sugar. Your body also needs insulin on a regular basis to keep your blood sugar in a target range. Rapid-acting and short-acting insulins reduce blood sugar levels quickly and then wear off. When you use intermediate- or long-acting insulin with rapid- or short-acting insulins, the longer acting insulin starts taking effect when the shorter acting insulin begins to wear off. For example, the long-acting insulin glargine (Lantus) starts to work within 1 to 2 hours after Continue reading >>
- Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes
- Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE)
- Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls
Humulin R For Boluses And Humalog For Corrections
Humulin R for boluses and Humalog for corrections Humulin R for boluses and Humalog for corrections I can't bolus with Humalog because of Gastropresis as it's action doesn't match with glucose But Humulin R suits me but it takes too long to correct spikes Can we take Humulin R for bolus and humalog for corrections Would be grateful if you could please answer my question D.D. Family T1 since 1985, MM Pump 2013, CGM 2015 I don't see why not. You'll need a Doc to write the script for the Humalog, and it may be a few hoops to get insurance to cover both. But I certainly see the logic. D.D. Family T1 since 1966, pumper since '03, transplant '08 Sure. Many moons ago I took my R & N shot in the morning (lantus was not yet available), took my humalog that I'd sort of worked out with the N peak, at dinner, and then took another shot of N at bedtime. It worked well enough at the time. If the R matches your digestion, then go for it! T1 since 1966, dialysis in 2001, kidney transplant in 02 from my cousin, pumping 03 - 08, pancreas transplant Feb 08 Continue reading >>
- Caffeinated and Decaffeinated Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review and a Dose-Response Meta-analysis
- Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls
- St. Luke’s Spotlights Critical Link Between Type 2 Diabetes and Heart Disease in Partnership with Boehringer Ingelheim and Eli Lilly and Company
