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Humulin R Classification

Insulin Regular Human (rx, Otc)

Insulin Regular Human (rx, Otc)

Dosage Forms & Strengths injectable solution Type 1 Diabetes Mellitus Initial: 0.2-0.4 units/kg/day SC divided q8hr or more frequently Maintenance: 0.5-1 unit/kg/day SC divided q8hr or more frequently; in insulin-resistant patients (eg, due to obesity), substantially higher daily insulin may be required Approximately 50-75% of the total daily insulin requirements are given as intermediate- or long-acting insulin administered in 1-2 injections; rapid- or short-acting insulin should be used before or at mealtimes to satisfy the remainder balance of the total daily insulin requirements Premixed combinations are available that deliver rapid- or short-acting components at the same time as the intermediate- or long-acting component Type 2 Diabetes Mellitus Type 2 diabetes inadequately controlled by diet, exercise, or oral medication: Suggested beginning dose of 10 units/day SC (or 0.1-0.2 unit/kg/day) in evening or divided q12hr Severe Hyperglycemia (Diabetic Ketoacidosis) 0.1 unit/kg/hr IV continuous infusion; if serum glucose does not fall by 50 mg/dL in the first hour, check hydration status; if possible, double the insulin hourly until glucose levels fall at the rate of 50-75 mg/dL/hr; decrease infusion to 0.05-0.1 unit/kg/hour when blood sugar reaches 250 mg/dL Dosing Considerations Dosage of human insulin, which is always expressed in USP units, must be based on the results of blood and urine glucose tests and must be carefully individualized to optimal effect Dose adjustments should be based on regular blood glucose testing Adjust to achieve appropriate glucose control Look for consistent pattern in blood sugars for >3 days Same time each day: Compare blood glucose levels with previous levels found at that time of day For each time of day: Calculate blood glucose range Continue reading >>

Phase Ii Pharmacokinetics Study Of Humalog And Humulin-r With And Without Rhuph20 In Type 1 Diabetes Mellitus

Phase Ii Pharmacokinetics Study Of Humalog And Humulin-r With And Without Rhuph20 In Type 1 Diabetes Mellitus

You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. ClinicalTrials.gov Identifier: NCT00774800 Information provided by (Responsible Party): Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information Humalog and Humulin-R (recombinant human insulin) are Food and Drug Administration (FDA) approved medications for the treatment of diabetes mellitus. Recombinant human hyaluronidase PH20 (rHuPH20) is approved by the FDA for use as an aid in the absorption and dispersion of other injectable drugs. In this study, rHuPH20 will be co-administered with both Humalog and Humulin-R in order to determine if it improves the absorption of these insulins to more closely mimic the body's natural increase in insulin in response to a meal. Drug: Humalog Drug: Humulin-R Drug: Recombinant human hyaluronidase PH20 (rHuPH20) Other: Liquid meal Participants received all 4 interventions in the same order. Dose-finding visits were conducted to identify the appropriate dose of Humalog and Humulin-R. For each Humalog dose-finding visit, a total of 24 U of rHuPH20 was injected SC per unit of Humalog, corresponding to a mass concentration of 18.2 micrograms per milliliter (g/mL) rHuPH20 (at final concentration of 91 U/mL of Humalog). For each Humulin-R dose-finding visit, a total of 24 U of rHuPH20 was injected SC per unit of Humulin-R Continue reading >>

Humulin R

Humulin R

Generic Name: Insulin Regular (U-100) Vials (IN su lin) Brand Name: Humulin R, Novolin R Uses of Humulin R: It is used to lower blood sugar in patients with high blood sugar (diabetes). What do I need to tell my doctor BEFORE I take Humulin R? If you have an allergy to insulin or any other part of Humulin R (insulin regular (U-100) vials). If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have low blood sugar. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Humulin R with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Humulin R? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. Allergic reactions have happened with Humulin R. Rarely, some reactions can be very bad or life-threatening. Talk with the doctor. Low blood sugar may happen with this medicine. Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death. Talk with the doctor. Low blood potassium may happen with Humulin R. If not treated, this can lead to a heartbeat that is not normal, very bad breathing problems, and sometimes death. Talk with the doctor. Avoid driving and doing other tasks or actions that Continue reading >>

5 Types Of Insulin And How They Work

5 Types Of Insulin And How They Work

What you need to know If you have to take insulin to treat diabetes, there’s good news: You have choices. There are five types of insulin. They vary by onset (how soon they start to work), peak (how long they take to kick into full effect) and duration (how long they stay in your body). You may have to take more than one type of insulin, and these needs may change over time (and can vary depending on your type of diabetes). Find out more about the insulin types best for you. Rapid-acting insulin What it’s called: Humalog (lispro), NovoLog (aspart), Apidra (glulisine) Rapid-acting insulin is taken just before or after meals, to control spikes in blood sugar. This type is typically used in addition to a longer-acting insulin. It often works in 15 minutes, peaks between 30 and 90 minutes, and lasts 3 to 5 hours. “You can take it a few minutes before eating or as you sit down to eat, and it starts to work very quickly,” says Manisha Chandalia, MD, director of the Stark Diabetes Center at the University of Texas Medical Branch, in Galveston. Short-acting insulin What it’s called: Humulin R, Novolin R Short-acting insulin covers your insulin needs during meals. It is taken about 30 minutes to an hour before a meal to help control blood sugar levels. This type of insulin takes effect in about 30 minutes to one hour, and peaks after two to four hours. Its effects tend to last about five to eight hours. “The biggest advantage of short-acting insulin is that you don't have to take it at each meal. You can take it at breakfast and supper and still have good control because it lasts a little longer,” Dr. Chandalia says. Intermediate-acting insulin What it’s called: Humulin N (NPH), Novolin N (NPH) Intermediate-acting insulin can control blood sugar levels for about Continue reading >>

Fda Approves Lillys Humulin R U-500 Kwikpen

Fda Approves Lillys Humulin R U-500 Kwikpen

Home / Resources / Articles / FDA Approves Lillys Humulin R U-500 KwikPen FDA Approves Lillys Humulin R U-500 KwikPen New pen may improve glycemic control in people with severely insulin-resistant diabetes. For the first time Humulin % U-500 will now be available in a pen. This will help to prevent all the errors that this insulin has had in the past because of the confusion with units and ccs. The U.S. Food and Drug Administration (FDA) has approved Eli Lilly and Companys Humulin R U-500 KwikPen (insulin human injection) 500 units/mL, a pre-filled device containing Humulin R U-500, a highly concentrated formulation of insulin. Humulin R U-500 is the only FDA-approved insulin that is five times more concentrated than standard U-100 insulin. This insulin is used to treat high blood sugar in people with type 1 and type 2 diabetes who need more than 200 units of insulin per day. The safety and efficacy of Humulin R U-500 used in combination with other insulins or delivered by an insulin infusion pump has not been determined. People with diabetes and severe insulin resistance who have become poorly responsive to the effects of insulin may require much higher insulin doses more than 200 units per day to help keep their blood sugar levels on target, said Jeffrey A. Jackson, MD, FACE, CDE, Medical Fellow, US Medical Affairs, Lilly Diabetes. For these patients, the U-500 KwikPen is now available as a convenient alternate option to deliver a large dose of insulin in a reasonable volume. It was specifically designed as a dedicated dosing device to eliminate the need for dose conversion, as compared to use of the vial and syringe options, which some people may find to be an improvement. Until now, Humulin R U-500 was only available in a vial, administered with either a U-100 insu Continue reading >>

Week 1 Drug Cards - #1 Generic Name Regular Insulin Trade...

Week 1 Drug Cards - #1 Generic Name Regular Insulin Trade...

week 1 drug cards - #1 GENERIC NAME Regular Insulin TRADE... #1 GENERIC NAME: Regular InsulinTRADE NAME: Humulin R, NovoLin R, HumuLin R U-500 Indication: (What Disease):Control of hyperglycemia in PT w/ diabetes mellitus; Unlabeled use: treatment of hyperkalemia*Pre Assessment Data: Blood glucose level, allergies, vital signs, potassium level*Classification:Antidiabetic / Hormones, Pancreatic *Routes/ Max Dose: Dose depends on blood glucose, response & other factors. IV or SC. IV(Adult) 0.1 unit/kg/hr as continuous infusion. IV(Children) loading dose 0.1 unit/kg, then maintenance continuous infusion 0.05 0.2 unit/kg/hr. SC (Adult and Children) 0.5- 1 unit/kg/day in divided doses. Adolescents during rapid growth 0.8 1.2 unit/kg/day in divided doses. Action/How does it do its job? Lowers blood glucose by stimulating glucose uptake in skeletal muscle and fat, inhibiting hepatic glucose production. Inhibition of lipolysis and proteolysis, enhanced protein synthesis.Contraindications:Hypoglycemia, allergy or hypersensitivity to a particular type of insulin, preservatives or other additives. Use cautiously: Stress or infection may temporarily raise insulin requirements. Side Effects: Hypoglycemia,lipodystrophy, pruritus, erythema, swelling, allergic reaction *Post Assessment Data:Monitor blood glucose every 6 hr during therapy, more frequently in ketoacidosis and time of stress. A1C may be monitored every 3-6 months to determine effectiveness. Assess Pt for symptoms of hypoglycemia (anxiety, restlessness, tingling in hands, feet, lips or tongue, chills; cold sweats; difficulty in concentration, drowsiness, nightmares; excessive hunger, headache, irritability, nausea, nervousness, tachycardia, tremor, weakness, unsteady gait). *Patient Teaching: Follow instructions for prope Continue reading >>

Insulin Therapy For Diabetes Mellitus In Dogs And Cats (proceedings)

Insulin Therapy For Diabetes Mellitus In Dogs And Cats (proceedings)

It is very important for clinicians prescribing insulin to understand their classification. Insulins may be classified by insulin source, insulin formulation, or duration of action. Not all forms of insulin are currently commercially available and product availability is likely to continue to change. Insulin formulations that have been available historically include short duration regular insulin (designated R), moderate duration NPH insulin (designated N), moderate duration Lente insulin (designated L), Long duration Ultralente insulin (designated U), and Long duration PZI insulin. Insulins may be derived from bovine, porcine, or human recombinant sources and the concentration may be either 100 units/ml (human products) or 40 units/ml (veterinary products). A number of human recombinant insulin analogues are also available. The types of insulin recommended for use in dogs and cats has been complicated by the recent disappearance of many insulin products from the market. The insulin products that are currently available in the US are listed below: Insulin products currently available and recommended for use in dogs and cats Regular insulin (Zinc insulin crystals) Products: Humulin R [Lilly], Novolin R [NovoNordisk] Both human recombinant. 100 U/ml NPH insulin (neutral protamine hagedorn) o Complexed with protamine zinc in phosphate buffer Products: (Humulin N [Lilly], Novolin N [NovoNordisk] Both human recombinant 100 U/ml Lente insulin (3 percent semilente, seventy percent ultralente) o mix of crystalline and amorphous crystals in zinc acetate buffer Products: Vetsulin [Intervet] Pure pork insulin (40 U/ml) o Insulin complexed with protamine and zinc. Products: ProZinc [Boehringer Ingelheim] human recombinent (40 U/ml) o Insulin analogue Products: Lantus [Sanofi-Avent Continue reading >>

Regular Insulin Classification

Regular Insulin Classification

Insulin. ... Insulin regular; Insulin, human; Regular Insulin, human; Product Ingredients . It takes effect within 30 minutes and has a duration of activity of approximately 4 to 12 hours. Ingredient UNII CAS View Notes - 1 Drug Cards Regular Insulin from NURSING 200 at National University of Health Sciences. When mixing insulins, draw regular insulin into syringe rst to avoid contamina-tionofregularinsulinvial. In general, regular insulin is drawn up into syringe first. Regular Human Insulin which has an onset of action of 1/2 hour to 1 hour, peak effect in 2 to 4 hours, and duration of action of 6 to 8 hours. Start studying 13) Regular Insulin. Diabetes Classification Table. Drug action in the body 2. The larger the dose of regular the faster the onset of action, but the longer the time Types: Insulin glulisine (Apidra), insulin lispro (Humalog), and insulin aspart (NovoLog) Regular or Short-acting insulin usually reaches the bloodstream within 30 minutes after injection, peaks anywhere from 2 to 3 hours after injection, and is effective for approximately 3 to 6 hours. Drug Classification. Insulin Regular (Human) is an injectable medication used to treat type 1 and type 2 diabetes. Regular insulin is used to treat diabetes. Insulin Diabetes >> Diabetes and Insulin >> Diabetes Insulin Classification: Diabetes Insulin Classification . Humulin 70/30, Novolin 70/30 (NPH/regular insulin mixtures) Therapeutic Classification: antidiabetics, hormones Pharmacologic Classification: pancreatics ... Insulin regular; Insulin, human; Regular Insulin, human; Product Ingredients . Administration. Learn about the different types of insulin for people with diabetes, including rapid-acting, short-acting, intermediate-acting & long acting insulin. Only regular insulin, insulin lispro, i Continue reading >>

Regular Insulin Classification

Regular Insulin Classification

Generic/Trade Names Classification Physician's Order 1. Insulin Glargine is a recombinant human insulin analog with long-acting, blood glucose-lowering activity. The use of insulin does not, of itself, classify the diabetes. Learn about the different types of insulin for people with diabetes, including rapid-acting, short-acting, intermediate-acting & long acting insulin. Types: Insulin glulisine (Apidra), insulin lispro (Humalog), and insulin aspart (NovoLog) Regular or Short-acting insulin usually reaches the bloodstream within 30 minutes after injection, peaks anywhere from 2 to 3 hours after injection, and is effective for approximately 3 to 6 hours. The larger the dose of regular the faster the onset of action, but the longer the time ... Insulin regular; Insulin, human; Regular Insulin, human; Product Ingredients . Ingredient UNII CAS Drug Classification. ... Insulin regular; Insulin, human; Regular Insulin, human; Product Ingredients . In general, regular insulin is drawn up into syringe first. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Insulin Regular (Human) is an injectable medication used to treat type 1 and type 2 diabetes. Regular insulin is used to treat diabetes. Regular insulin is a short acting insulin and NPH insulin is an intermediate acting insulin. It is a cluster of @ Treatment Of Diabetes Before Insulin Diabetes Classification The 3 Step Trick that Reverses Diabetes Permanently in As Little as 11 Days. Ingredient UNII CAS Insulin. ... Types and Activity (Chapter 8 Insulin: Types and Activity. Insulin is a hormone that is produced in the body. Only regular insulin, insulin lispro, insulin glulisine, and insulin aspart should be used for continuous subcutaneous insulin infusion (CSII) administration in external Continue reading >>

Insulin Injection

Insulin Injection

Insulin injection is used to control blood sugar in people who have type 1 diabetes (condition in which the body does not make insulin and therefore cannot control the amount of sugar in the blood) or in people who have type 2 diabetes (condition in which the blood sugar is too high because the body does not produce or use insulin normally) that cannot be controlled with oral medications alone. Insulin injection is in a class of medications called hormones. Insulin injection is used to take the place of insulin that is normally produced by the body. It works by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar. All of the types of insulin that are available work in this way. The types of insulin differ only in how quickly they begin to work and how long they continue to control blood sugar. Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes. Insulin comes as a solution (liquid) and a suspension (liquid with particles that will settle on standing) to be injected subcutaneousl Continue reading >>

Buy Humulin R - Prime Anabolics

Buy Humulin R - Prime Anabolics

Pharmaceutical name: Insulin Human Injection (rDNA origin) Humulin R is an injectable drug, contains Insulin Human Injection and is made by Eli Lilly. Insulin is a hormone produced in the pancreas which helps to regulate glucose levels in the body. Medically, it is typically used in the treatment of diabetes. Recently, insulin has become quite popular among bodybuilders due to the anabolic effect it can offer. With well-times injections, insulin will help to bring glycogen and other nutrients to the muscle. Humulin R is the compound most used by the way because its the shortest acting form. Yes, thats a good thing. In fact its a very good thing. When administering supra-physiological doses of insulin, more glucose is stored as glycogen resulting in a lower blood sugar level. When your blood sugar level is too low, its called hypoglycemia and it can cause you to go into shock and die. If proper protocol for using insulin is not followed, you can die. This has two definite implications. First of all it explains why you want the short-acting form. Blood sugar levels need to be monitored over the active time, so you obviously dont want it to stay active for 24 hours or longer. The second implication is that obviously sugar has to be taken with the insulin to prevent hypoglycemia and sugar needs to be kept on hand for the entire duration of activity, which is 6-8 hours. If dizziness or weakness occurs, more sugar has to be taken. This will be discussed in the how to use section. Initially, doses of insulin will make you leaner as you store more carbs that would otherwise be stored as fat. But as people will tell you, it eventually has a tendency to make you fat. As indicated earlier, there is no negative feedback, but cells develop a resistance to insulin, in which case cir Continue reading >>

Humulin R Regular U-100 Insulin Injection : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - Webmd

Humulin R Regular U-100 Insulin Injection : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - Webmd

Insulin regular is used with a proper diet and exercise program to control high blood sugar in people with diabetes . Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke . This man-made insulin product is the same as human insulin . It replaces the insulin that your body would normally make. It is a short-acting insulin. It works by helping blood sugar ( glucose ) get into cells so your body can use it for energy. This medication is usually used in combination with a medium- or long-acting insulin product. This medication may also be used alone or with other oral diabetes drugs (such as metformin ). Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist. Learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the insulin . Insulin regular should be clear and colorless. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin and to avoid developing problems under the skin ( lipodystrophy ). Insulin regular may be injected in the stomach area, the thigh, the buttocks, or the back of the upper arm. Do not inject into a vein or muscle because very low blood sugar ( hypoglycemia ) may occur. Do not rub the area after the injection. Do not inject into skin that is red, swollen, or itchy. Do not inject cold insulin because thi Continue reading >>

Brand Names: Humulin R, Novolin R, Novolin R Innolet, Novolin R Penfill, Relion/novolin R

Brand Names: Humulin R, Novolin R, Novolin R Innolet, Novolin R Penfill, Relion/novolin R

A A A Medications and Drugs Generic Name: insulin regular (Pronunciation: IN soo lin REG yoo lar) What is insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What are the possible side effects of insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What is the most important information I should know about insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What should I discuss with my healthcare provider before using insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? How should I use insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What happens if I miss a dose (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What happens if I overdose (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What should I avoid while using insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What other drugs will affect insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? What is insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? Insulin is a hormone that is produced in the body. It works by lowering levels of glucose (sugar) in the blood. Insulin regular is a short-acting form of insulin. Insulin regular is used to treat diabetes. Insulin regular may also be used for other purposes not listed in this medication guide. What are the possible side effects of insulin regular (Humulin R, Novolin R, Novolin R Innolet, Novolin R PenFill, ReliOn/Novolin R)? Get emergency medical help if you Continue reading >>

Insulin (medication)

Insulin (medication)

"Insulin therapy" redirects here. For the psychiatric treatment, see Insulin shock therapy. Insulin is used as a medication to treat high blood sugar.[3] This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but some forms may also be used by injection into a vein or muscle.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Insulin can be made from the pancreas of pigs or cows.[5] Human versions can be made either by modifying pig versions or recombinant technology.[5] It comes in three main types short–acting (such as regular insulin), intermediate–acting (such as NPH insulin), and longer-acting (such as insulin glargine).[5] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[6] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[7] The wholesale cost in the developing world is about US$2.39 to $10.61 per 1,000 iu of regular insulin and $2.23 to $10.35 per 1,000 iu of NPH insulin.[8][9] In the United Kingdom 1,000 iu of regular or NPH insulin costs the NHS 7.48 pounds, while this amount of insulin glargine costs 30.68 pounds.[5] Medical uses[edit] Giving insulin with an insulin pen. Insulin is used to treat a number of diseases including diabetes and its acute complications such as diabetic ketoacid Continue reading >>

Regular Insulin

Regular Insulin

Regular insulin, also known as neutral insulin and soluble insulin is a type of short acting insulin.[1] It is used to treat diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It is also used along with glucose to treat high blood potassium levels.[4] Typically it is given by injection under the skin, but may also be used by injection into a vein or muscle.[1] Onset of effect is typically in 30 minutes and they last for 8 hours.[3] The common side effect is low blood sugar.[3] Other side effects may include pain or skin changes at the sites of injection, low blood potassium, and allergic reactions.[3] Use during pregnancy is relatively safe for the baby.[3] Regular insulin can be made from the pancreas of pigs or cows.[1] Human versions can be made either by modifying pig versions or recombinant technology.[1] Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922.[5] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[6] The wholesale cost in the developing world is about 2.39 to 10.61 USD per 1,000 iu of regular insulin.[7] In the United Kingdom 1,000 iu costs the NHS 7.48 pounds, while in the United States this amount is about 134.00 USD.[1][8] Versions are also available mixed with longer–acting versions of insulin, such as NPH insulin.[1] Medical uses[edit] It is used for the long term management of diabetes.[3] Regular insulin is the treatment of choice for the two diabetic emergencies diabetic ketoacidosis and hyperosmolar hyperglycemic states.[3] It may also be used in combination with glucose to lower potassium leve Continue reading >>

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