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Humulin

Humulin U-500: Counseling Your Patients

Humulin U-500: Counseling Your Patients

Pharmacists looking to counsel patients on Humulin R U-500 can use counseling points that are very similar to U-100, which patients often find comforting. To begin with the product, which is a concentrated insulin that is typically considered in patients injecting large volumes of U-100, should be clear and colorless at all times. They should be administering the insulin 30 minutes before their meal(s). The most common adverse effect reported with Humulin R U-500 is hypoglycemia. Studies show that patients are at risk for severe hypoglycemia as long as 18-24 hours post injection and should always be considered a risk factor if the patient is found unresponsive. For this reason patients should also be cautious while driving/operating heavy machinery at all times, but especially when first starting this medication as well as any dose changes. To minimize the risk of hypoglycemia, Humulin R U-500 should not be administered IV, IM, or via insulin pump in a hospital setting or outpatient. Other common adverse effects would include lipodystrophy, weight gain, edema, allergic reactions, and/or immunogenicity (antibody formulation). Considered a Pregnancy Category B, this product, like other insulin products should be used in pregnant women with both caution and care but it is noteworthy that Humulin R U-500 does not pose any greater risk. The insulin does pass into the breast milk and gets ingested by the infant, however, the insulin is broken down into the gastrointestinal tract and does not raise any concern, therefore, it is safe to administer while breastfeeding. Commercially available as both a KwikPen and vials, the KwikPens are 3 mL and contain 1,500 units in each pen availablein packs of 2 and 3 pens, while the vials are available as 20 mL containing 10,000 units of i Continue reading >>

Humulin Nph (vial) Suspension For Injection

Humulin Nph (vial) Suspension For Injection

Consumer medicine information (CMI) leaflet Please read this leaflet carefully before you start using Humulin NPH (Vial) Suspension for injection. Download CMI (PDF) Download large text CMI (PDF) What is in this leaflet This leaflet answers some common questions about HUMULIN. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMULIN and its use that you should be aware of. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HUMULIN against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Keep this leaflet with this medicine. You may need to read it again. What HUMULIN is used for HUMULIN is used to reduce high blood sugar (glucose) levels in patients with diabetes mellitus. Diabetes mellitus is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. There are two types of diabetes mellitus: Type 1 diabetes - also called juvenile onset diabetes. Type 2 diabetes - also called maturity onset diabetes. Patients with type 1 diabetes always require insulin to control their blood sugar levels. Some patients with type 2 diabetes may also require insulin after initial treatment with diet, exercise and tablets. HUMULIN is identic Continue reading >>

Humulin N (insulin Isophane Aka Insulin Nph)

Humulin N (insulin Isophane Aka Insulin Nph)

Humulin N is one brand of the man-made form of insulin known as insulin NPH or insulin isophane. It is produced by Eli Lilly and Company using recombinant DNA technology from a non-pathological strain of E. coli. It combines human insulin with protamine sulfate to create a crystalline suspension. Humulin N is used to help lower blood glucose levels in people with diabetes. Humulin N is one of the few insulins available without a prescription in some states (although you must ask for it at the pharmacy counter, since it has to stay refrigerated). How Does Humulin N Work? Humulin N is an intermediate-acting insulin, which begins to take effect between one and four hours after injection. Its peak effect occurs four to 12 hours after injection and keeps working for 12 to 18 hours after injection. For some people, it can take 24 hours to clear out of their system. Humulin N acts like your body’s natural insulin to lower or normalize your blood sugar levels. It is often used in conjunction with a short-acting insulin and/or other oral anti-diabetic medications (such as Metformin). This insulin can also be mixed with certain other insulins, such as regular insulin. Consult with your doctor on whether mixing insulins is right for you. They can also instruct you on the correct way to do so. Humulin N can be used to improve glycemic control in adults and children with diabetes. Who Should Not Take Humulin N? Do not take Humulin N if you are experiencing hypoglycemia (low blood sugar). Do not take Humulin N if you are allergic to insulin isophane or any of its ingredients: dibasic sodium phosphate, glycerol, m-cresol, phenol, protamine sulfate, and zinc. It may also contain dimethicone, hydrochloric acid, and sodium hydroxide. If your doctor prescribes Humulin N, you will inject Continue reading >>

Humulin® Vials

Humulin® Vials

PDFLARGE FONT PDF Biosynthetic Human Insulin (rbe) Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about HUMULIN. It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. The information in this leaflet was last updated on the date shown on the final page. More recent information on this medicine may be available. Make sure you speak to your pharmacist, nurse or doctor to obtain the most up to date information on this medicine. You can also download the most up to date leaflet from www.lilly.com.au. The updated leaflet may contain important information about HUMULIN and its use that you should be aware of. All medicines have risks and benefits. Your doctor has weighed the risks of you taking HUMULIN against the benefits they expect it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Keep this leaflet with this medicine. You may need to read it again. What HUMULIN is used for HUMULIN is used to reduce high blood sugar (glucose) levels in patients with diabetes mellitus. Diabetes mellitus is a condition in which your pancreas does not produce enough insulin to control your blood sugar level. Extra insulin is therefore needed. There are two types of diabetes mellitus: Type 1 diabetes - also called juvenile onset diabetes. Type 2 diabetes - also called maturity onset diabetes. Patients with type 1 diabetes always require insulin to control their blood sugar levels. Some patients with type 2 diabetes may also require insulin after initial treatment with diet, exercise and tablets. HUMULIN is identical to the insulin produced by the pancreas. There are 3 different types of HUMULIN vials: HUMULIN R HUMULIN NPH HUM Continue reading >>

What Is Humulin R (insulin Regular)?

What Is Humulin R (insulin Regular)?

Humulin R is the brand name of a medicine that contains insulin regular (a short-acting form of insulin). Insulin is a hormone that's produced by the body in the pancreas. It works to lower levels of sugar in the blood. This prescription medicine is injected to improve blood sugar control in adults with diabetes. The U.S. Food and Drug Administration (FDA) first approved human insulin in 1982. Humulin R is marketed by Ely Lilly and Company. Humulin R Warnings Humulin R shouldn't be used during an episode of hypoglycemia (low blood sugar). Low blood sugar is a common side effect of insulin. Symptoms may include: Hunger Headache Weakness Sweating Irritability Tremors Trouble concentrating Fast heartbeat Fainting Seizures Look out for signs of low blood sugar, and carry candy or glucose tablets in case you have an episode. You may also experience signs of hyperglycemia (high blood sugar), which often include: Hunger Increased thirst Dry mouth Fruity breath odor Dry skin Blurred vision Weight loss Increased urination Drowsiness You'll need to monitor your blood sugar levels often while taking this medicine. It's important that you keep Humulin R with you at all times. Be sure to get your prescription refilled before you run out of this medicine. Don't change the brand of insulin or type of syringe you're using without first talking to your healthcare provider. They may not be interchangeable. Before taking Humulin R, tell your doctor if you have, or have ever had: Kidney or liver disease Heart failure, or other heart problems Nerve, adrenal, pituitary, or thyroid problems Eye problems caused by diabetes Allergies to medications Let your doctor know about all the medicines you're taking while using Humulin R, especially certain oral diabetes drugs, such as Actos (pioglitazon Continue reading >>

Humulin N

Humulin N

HUMULIN® N (human insulin [rDNA origin]) isophane) Suspension DESCRIPTION HUMULIN N (human insulin [rDNA origin] isophane) suspension is a human insulin suspension. Human insulin is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. HUMULIN N is a suspension of crystals produced from combining human insulin and protamine sulfate under appropriate conditions for crystal formation. The amino acid sequence of HUMULIN N is identical to human insulin and has the empirical formula C257H383N65O77S6 with a molecular weight of 5808. HUMULIN N is a sterile white suspension. Each milliliter of HUMULIN N contains 100 units of insulin human, 0.35 mg of protamine sulfate, 16 mg of glycerin, 3.78 mg of dibasic sodium phosphate, 1.6 mg of metacresol, 0.65 mg of phenol, zinc oxide content adjusted to provide 0.025 mg zinc ion, and Water for Injection. The pH is 7.0 to 7.5. Sodium hydroxide and/or hydrochloric acid may be added during manufacture to adjust the pH. Continue reading >>

Humulin R Versus Humalog: A Side-by-side Comparison

Humulin R Versus Humalog: A Side-by-side Comparison

Diabetes is a disease that causes high blood sugar levels. Left untreated, high blood sugar levels can cause many problems, such as heart and blood vessel disease, stroke, kidney failure, and blindness. Humulin R and Humalog are two different types of insulin that can help lower your blood sugar level. These drugs work in slightly different ways. In general, insulin lowers your blood sugar level by signaling to your muscle and fat cells to use sugar from your blood. It also signals your liver to stop making sugar. Depending on the type and severity of your diabetes, you may need to take insulin. We’ll compare and contrast Humulin R and Humalog to help you decide if one may be a good choice to treat your diabetes. Humulin R is a brand name for regular insulin. It is a short-acting insulin. That means that it takes about 30 minutes to reach your bloodstream and works for about three to six hours. Humalog is a brand name for insulin lispro, which is a fast-acting insulin. It takes about 15 minutes to start working, but it only lasts two to four hours. The following table compares more features of these two drugs. Humulin R Humalog What drug is it? Regular insulin (short-acting insulin) Insulin lispro (fast-acting insulin) What’s it used for? Blood sugar control in people with diabetes Blood sugar control in people with diabetes Do I need a prescription to buy this drug? No Yes Is a generic version available? No No What forms does it come in? Injectable solution, available in a vial for use with a syringe Injectable solution, available in a vial for use with a syringe. Injectable solution, available in a cartridge that you use in a device called a KwikPen How much do I take? Your doctor will tell you what dose to inject. This depends on your blood sugar readings and the Continue reading >>

Humulin N, 70/30 Pens To Be Replaced By Kwikpens

Humulin N, 70/30 Pens To Be Replaced By Kwikpens

Humulin N, 70/30 Pens to Be Replaced by KwikPens Eli Lilly has announced that their Humulin N ( insulin isophane suspension [NPH]) and Humulin 70/30 ( insulin isophane suspension [NPH] 70% [human, recombinant], regular insulin 30% [human, recombinant]) original prefilled pens will be phased out in the first quarter of 2014. Humulin N and Humulin 70/30 are indicated for adults with diabetes mellitus to improve glycemic control, and Humulin N is also indicated for children with diabetes mellitus. RELATED: Endocrine Disorders Resource Center The original Prefilled Pens will be replaced with the Humulin N and Humulin 70/30 KwikPens, which will carry a different National Drug Code (NDC) and will function differently. Patients may need initial instructions on how to use the device and Eli Lilly is encouraging distributors and pharmacies to carry both devices during the transition to meet patient needs. Humulin N and Humulin 70/30 KwikPens will be available in 3.0mL disposable pens in 5-count boxes. For more information call (800) 545-5979 or visit Humulin.com . Continue reading >>

Humulin R Regular U-100 Insulin Injection : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - Webmd

Humulin R Regular U-100 Insulin Injection : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - Webmd

Insulin regular is used with a proper diet and exercise program to control high blood sugar in people with diabetes . Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke . This man-made insulin product is the same as human insulin . It replaces the insulin that your body would normally make. It is a short-acting insulin. It works by helping blood sugar ( glucose ) get into cells so your body can use it for energy. This medication is usually used in combination with a medium- or long-acting insulin product. This medication may also be used alone or with other oral diabetes drugs (such as metformin ). Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist. Learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the insulin . Insulin regular should be clear and colorless. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin and to avoid developing problems under the skin ( lipodystrophy ). Insulin regular may be injected in the stomach area, the thigh, the buttocks, or the back of the upper arm. Do not inject into a vein or muscle because very low blood sugar ( hypoglycemia ) may occur. Do not rub the area after the injection. Do not inject into skin that is red, swollen, or itchy. Do not inject cold insulin because thi Continue reading >>

Humulin - Definition Of Humulin By The Free Dictionary

Humulin - Definition Of Humulin By The Free Dictionary

Humulin - definition of Humulin by The Free Dictionary A trademark for any of a group of drugs containing genetically engineered synthetic human insulin. ThesaurusAntonymsRelated WordsSynonymsLegend: Humulin - a form of insulin (trade name Humulin) made from recombinant DNA that is identical to human insulin; used to treat diabetics who are allergic to preparations made from beef or pork insulin Want to thank TFD for its existence? Tell a friend about us , add a link to this page, or visit the webmaster's page for free fun content . For example, since 2007, the cost of Humulin R U-500 (human insulin) has increased 354%, EpiPen (epinephrine) has increased 222%, and Avonex (for multiple sclerosis) has increased 147%. xx Actos, Amaryl, Avandamet, Avandia, chlorpropamide, Diabeta, Diabinese, Fortamet, Glipizide, Glipizide ER, Glipizide XL,Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glucovance, glyburide, glyburide micronized, glyburide-metformin, Glynase, Glyset, Humalog, Humalog Mix 75/25, Humulin 50/50, Humulin 70/30, Humulin L, Humulin N, Humulin R, Humulin U, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin NPH, Lantus, Metaglip, metformin, metformin ER, Micronase, Novolin 70/30, Novolin L, Novolin N, Novolin R, Novolog, Novolog Mix 70/30, Prandin, Precose, Riomet, Starlix, tolazamide, tolbutamide, Tolinase, Velosulin Human BR ED = Erectile dysfunction; ICD-9-CM = International Classification of Diseases, 9th Edition, Clinical Modification; HCTZ = hydrochlorothiazide. Continue reading >>

Humulin

Humulin

What is Diabetes? Diabetes is a disease where the body is either unable to make the protein insulin, or is able to make insulin, but is unable to use insulin. This results in an inability to metabolize (break down) blood glucose and an inability to store glycogen (the storage form of glucose) in the liver. Diabetes is a life-threatening disease. If left untreated, high glucose levels may damage a person's eyes, kidneys, nerves, or heart. Uncontrolled diabetes can lead to diabetic acidosis, in which toxic chemicals called ketones build up in the blood. Patients have sweet-smelling breath, and may suffer confusion, unconsciousness, and death. Diabetes is common. At least one in every 16 people has diabetes; and more than 10 million individuals with diabetes around the world rely on insulin to control their diabetes. What normally happens when a person (without diabetes) eats food? 1. Some of the food breaks down into sugars; one of these sugars is glucose, the body's main fuel. 2. Sugar enters the bloodstream, and the level of blood sugar begins to rise. 3. When the body senses an increase in blood sugar, it sends a signal to the pancreas. 4. The pancreas makes insulin and sends it into the bloodstream. 5. Insulin lowers the level of blood sugar by allowing sugar to pass from the bloodstream into the cells. 6. The level of sugar in the bloodstream falls as the sugar passes into the cells. 7. The body's cells use the sugar for fuel (ATP production). You feel energetic. When a person has diabetes, sugar stays in the bloodstream rather than entering cells because their body does not make or does not respond properly to insulin. They are unable to properly get energy from the food they eat. The symptoms of diabetes are hyperglycemia (elevated sugar levels in the urine and bl Continue reading >>

Humulin N

Humulin N

Humulin N (insulin human recombinant) [Human insulin (rDNA origin) isophane suspension] is a man-made insulin product indicated for glucose control in patients with diabetes. Hypoglycemia (low blood sugar) is a frequent side effect of Humulin N (insulin). Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, or seizure (convulsions). Other side effects of Humulin N include injection site reactions (pain, redness, irritation). Tell your doctor if you have serious side effects of Humulin including signs of low potassium level in the blood (such as muscle cramps, weakness, irregular heartbeat). Humulin N (insulin human recombinant) is administered by injection. Any change of insulin should be made cautiously and only under medical supervision. Changes in strength, manufacturer, type (e.g, regular, NPH, analog), species, or method of manufacture may result in the need to change dosage. Humulin N may interact with albuterol, clonidine, reserpine, guanethidine, or beta-blockers. Tell your doctor all medications and supplements you use. Humulin N (insulin human recombinant) should be used during pregnancy only if clearly needed. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is unknown if Humulin N passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding. Our Humulin N Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects t Continue reading >>

Humulin N

Humulin N

Generic Name: insulin isophane (IN soo lin EYE soe fane) Brand Names: HumuLIN N, HumuLIN N KwikPen, NovoLIN N, Relion NovoLIN N What is Humulin N? Humulin N (insulin isophane) is a man-made form of a hormone that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin isophane is an intermediate-acting insulin that starts to work within 2 to 4 hours after injection, peaks in 4 to 12 hours, and keeps working for 12 to 18 hours. Humulin N is used to improve blood sugar control in adults and children with diabetes mellitus. Humulin N may also be used for purposes not listed in this medication guide. Important information Do not use Humulin N if you are having an episode of hypoglycemia (low blood sugar). Never share an injection pen or syringe with another person, even if the needle has been changed. Hypoglycemia, or low blood sugar, is the most common side effect of Humulin N. Symptoms of low blood sugar may include headache, hunger, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Watch for signs of low blood sugar. Carry a piece of non-dietetic hard candy or glucose tablets with you in case you have low blood sugar. Before taking this medicine You should not use Humulin N if you are allergic to insulin isophane, or if you are having an episode of hypoglycemia (low blood sugar). Do not give Humulin N to a child without a doctor's advice. To make sure Humulin N is safe for you, tell your doctor if you have: liver or kidney disease; or low levels of potassium in your blood (hypokalemia). Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using Continue reading >>

Humulin - Uses, Side Effects, Interactions - Canoe.com

Humulin - Uses, Side Effects, Interactions - Canoe.com

How does this medication work? What will it do for me? Insulin is a naturally occurring hormone made by the pancreas that helps the body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels. There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. Regular insulin is a fast-acting insulin. It takes 30 to 60 minutes to begin working after injection, and has its maximum effect between 2 and 4 hours after injection. It stops working after 6 to 8 hours. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it. What form(s) does this medication come in? EachmL contains 100 units of human biosynthetic insulin (regular insulin). Nonmedicinal ingredients: glycerol and m-cresol; may also contain dimethicone, hydrochloric acid, and sodium hydroxide. EachmL contains 100 units of human biosynthetic insulin (regular insulin). Nonmedicinal ingredients: glycerol and m-cresol; ma Continue reading >>

Indication For Humulin R U-500

Indication For Humulin R U-500

If your A1C is uncontrolled on high doses of standard insulin—more than 200 units a day—you may have another diabetes treatment option. Humulin® R U-500 is 5x concentrated insulin* available in a U-500 KwikPen® or syringe and vial. U-500 lowered high blood sugar in a clinical study. † If your doctor has prescribed U-500 for you or a loved one, learn more here. † 24 week, open-label, randomized trial to compare the efficacy and safety of 2 dosing regiments (TID, n=162 vs BID, n=163) for U-500 insulin replacing high dose U-100 insulin (>200 units per day) with or without oral antihyperglycemic drugs in adult patients with uncontrolled type 2 diabetes. These regimens were found to be equivalent for A1C reduction over 24 weeks, and both were efficacious. Study conducted with U-100 insulin syringes and Humulin R U-500 vials. Continue reading >>

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