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Humalog Vs Humulin R

Different Types Of Insulin: What To Use And When?

Different Types Of Insulin: What To Use And When?

What’s the difference between the different types of insulin? Long-acting, short-acting, premixed, learn more about all three. You may have a lot of questions as you begin insulin therapy. What are the different types of insulin available? Which should I be using and when? Insulins differ based on 3 key factors: 1 how quickly they work when they peak how long they last (duration) This table compares these factors in the types of insulin available:2 Type Onset (How quickly it starts working) Onset (What it is most effective) Duration (How long it works) Timing of injection (When should it be given) Bolus insulins Rapid acting analogues Apidra/Humalog/NovoRapid 10-15 min 1-2 hours 3-5 hours Given with 1 or more meals per day. To be given 0-15 minutes before or after meals. Short-acting Humulin-R/Toronto 30 min 2-3 hours 6.5 hours Given with one or more meals per day. Should be injected 30-45 minutes before the start of the meal. Basal insulins Intermediate-acting Humulin-N/NPH 1-3 hours 5-8 hours Up to 18 hours Often started once daily at bedtime. May be given once or twice daily. Not given at any time specific to meals. Long-acting analogues Lantus Levemir 90 min Not applicable Lantus: Up to 24 hours Levemir: 16-24 hours Often started once daily at bedtime. Insulin detemir (Levemir) may be given once or twice daily. Not given at any time specific to meals. Premixed insulins Premixed regular insulin Humulin 30/70 and Novolin ge 30/70, 40/60, 50/50 Varies according to types of insulin Contains a fixed ratio of insulin (% of rapid-acting or short-acting insulin to % of intermediate-acting insulin): See above for information about peak actions based on insulin contained Given with one or more meals per day. Should be injected 30-45 minutes before the start of the meal. Pre Continue reading >>

What Are The Possible Side Effects Of Insulin Lispro (humalog, Humalog Cartridge, Humalog Kwikpen, Humalog Pen)?

What Are The Possible Side Effects Of Insulin Lispro (humalog, Humalog Cartridge, Humalog Kwikpen, Humalog Pen)?

HUMALOG (insulin lispro) Injection DESCRIPTION HUMALOG® (insulin lispro injection) is a rapid-acting human insulin analog used to lower blood glucose. Insulin lispro is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. Insulin lispro differs from human insulin in that the amino acid proline at position B28 is replaced by lysine and the lysine in position B29 is replaced by proline. Chemically, it is Lys(B28), Pro(B29) human insulin analog and has the empirical formula C257H383N65O77S6 and a molecular weight of 5808, both identical to that of human insulin. HUMALOG has the following primary structure: HUMALOG is a sterile, aqueous, clear, and colorless solution. Each milliliter of HUMALOG U-100 contains insulin lispro 100 units, 16 mg glycerin, 1.88 mg dibasic sodium phosphate, 3.15 mg Metacresol, zinc oxide content adjusted to provide 0.0197 mg zinc ion, trace amounts of phenol, and Water for Injection. Insulin lispro has a pH of 7.0 to 7.8. The pH is adjusted by addition of aqueous solutions of hydrochloric acid 10% and/or sodium hydroxide 10%. Each milliliter of HUMALOG U-200 contains insulin lispro 200 units, 16 mg glycerin, 5 mg tromethamine, 3.15 mg Metacresol, zinc oxide content adjusted to provide 0.046 mg zinc ion, trace amounts of phenol, and Water for Injection. Insulin lispro has a pH of 7.0 to 7.8. The pH is adjusted by addition of aqueous solutions of hydrochloric acid 10% and/or sodium hydroxide 10%. font size A A A 1 2 3 4 5 Next What is Type 2 Diabetes? The most common form of diabetes is type 2 diabetes, formerly called non-insulin dependent diabetes mellitus or "adult onset" diabetes, so-called because it typically develops in adults over age 35, though it can develop at any age. Type 2 diabetes i Continue reading >>

What Is The Difference Between Humalog Vs Humulin?

What Is The Difference Between Humalog Vs Humulin?

Humalog and Humulin refer to insulin medications that are used to reduce high blood sugar in people with diabetes. Insulin is a naturally occurring hormone that is produced by the beta cells in the pancreas. This hormone helps glucose (sugar) convert into energy for the cells in your body. Without insulin, glucose will not convert into energy, causing a build up of sugar in the blood and a lack of energy for the body. Too much glucose in the blood can lead to serious health problems, such as blindness, kidney failure and damage to blood vessels. Both medications can be used to control high blood sugar in people with diabetes. Humalog and Humulin may have similar drug interactions when used together with other medications. Sometimes these drug interactions can lead to harmful effects, such as low blood sugar, which is why you should inform your doctor about all medications you are using. Both drugs are injected under the skin to help reduce high blood sugar levels in people with diabetes. However, Humalog starts to work faster compared to Humulin. When you inject Humalog, it starts to work between 30 to 90 minutes. However, Humulin is most effective 3 hours after injecting it. What is Humalog? It is a rapid acting insulin analog that acts by improving glycemic control in people with type 2 diabetes. You should administer this medication within 15 minutes before your meal or immediately after you eat. What is Humulin? It is a man made form of the natural insulin produced by the pancreas. This insulin is used by people with type 2 diabetes to help improve their blood glucose levels in a similar way to how insulin works in people without diabetes. Humalog vs Humulin: The Side Effects There are some side effects that are common in both Humalog and Humulin. The most common ar Continue reading >>

Humulin R Versus Humalog: A Side-by-side Comparison

Humulin R Versus Humalog: A Side-by-side Comparison

Diabetes is a disease that causes high blood sugar levels. Left untreated, high blood sugar levels can cause many problems, such as heart and blood vessel disease, stroke, kidney failure, and blindness. Humulin R and Humalog are two different types of insulin that can help lower your blood sugar level. These drugs work in slightly different ways. In general, insulin lowers your blood sugar level by signaling to your muscle and fat cells to use sugar from your blood. It also signals your liver to stop making sugar. Depending on the type and severity of your diabetes, you may need to take insulin. We’ll compare and contrast Humulin R and Humalog to help you decide if one may be a good choice to treat your diabetes. Humulin R is a brand name for regular insulin. It is a short-acting insulin. That means that it takes about 30 minutes to reach your bloodstream and works for about three to six hours. Humalog is a brand name for insulin lispro, which is a fast-acting insulin. It takes about 15 minutes to start working, but it only lasts two to four hours. The following table compares more features of these two drugs. Humulin R Humalog What drug is it? Regular insulin (short-acting insulin) Insulin lispro (fast-acting insulin) What’s it used for? Blood sugar control in people with diabetes Blood sugar control in people with diabetes Do I need a prescription to buy this drug? No Yes Is a generic version available? No No What forms does it come in? Injectable solution, available in a vial for use with a syringe Injectable solution, available in a vial for use with a syringe. Injectable solution, available in a cartridge that you use in a device called a KwikPen How much do I take? Your doctor will tell you what dose to inject. This depends on your blood sugar readings and the Continue reading >>

Compare Human Insulin Vs. Humalog

Compare Human Insulin Vs. Humalog

Some types of this medication are available without a prescription. Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose. Available in different combinations so that you can do one shot or multiple shots a day. Humalog (insulin lispro) is the most effective medication for lowering your blood sugar. Humalog (insulin lispro) can be used even if you have liver or kidney problems, unlike other anti-diabetic medications. 57 reviews so far Have you used Humulin (Human Insulin)? Leave a review 280 reviews so far Have you used Humalog (insulin lispro)? Leave a review Continue reading >>

Biod-531 Vs. Humalog Mix 75/25 Vs. Humulin R U-500 Post-meal Glucose Control In Patients With Severe Insulin Resistance

Biod-531 Vs. Humalog Mix 75/25 Vs. Humulin R U-500 Post-meal Glucose Control In Patients With Severe Insulin Resistance

The study is designed to compare meal time glucose control associated with BIOD-531, a rapidly absorbed concentrated insulin to that associated with Humalog Mix 75/25 and Humulin R U-500 in patients with diabetes and severe insulin resistance. Study Type : Interventional (Clinical Trial) Actual Enrollment : 12 participants Allocation: Randomized Intervention Model: Crossover Assignment Masking: Single (Participant) Primary Purpose: Treatment Official Title: A Single-blind Crossover Study of the Pharmacokinetic and Postprandial Glucose Dynamics of BIOD-531 Compared to Humulin® R U-500 and Humalog® Mix75/25™ in Subjects With Type 2 DM Who Are Treated With ≥ 150 Units of Insulin Per Day Study Start Date : May 2014 Primary Completion Date : November 2014 Arm Intervention/treatment Experimental: BIOD-531 pre-meal Subcutaneous injections of 1.2 U/kg before the start of a standardized breakfast and 0.8 U/kg before the start of a standardized dinner. Drug: BIOD-531 Active Comparator: Humalog Mix 75/25 pre-meal Subcutaneous injections of 1.2 U/kg before the start of a standardized breakfast and 0.8 U/kg before the start of a standardized dinner. Drug: Humalog Mix 75/25 Active Comparator: Humulin R U-500 pre-meal Subcutaneous injections of 1.2 U/kg before the start of a standardized breakfast and 0.8 U/kg before the start of a standardized dinner. Drug: Humulin R U-500 Experimental: BIOD-531 post-meal Subcutaneous injections of 1.2 U/kg 20 minutes after the start of a standardized breakfast and 0.8 U/kg 20 minutes after the start of a standardized dinner. Drug: BIOD-531 Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To Continue reading >>

What Is Humulin R (insulin Regular)?

What Is Humulin R (insulin Regular)?

Humulin R is the brand name of a medicine that contains insulin regular (a short-acting form of insulin). Insulin is a hormone that's produced by the body in the pancreas. It works to lower levels of sugar in the blood. This prescription medicine is injected to improve blood sugar control in adults with diabetes. The U.S. Food and Drug Administration (FDA) first approved human insulin in 1982. Humulin R is marketed by Ely Lilly and Company. Humulin R Warnings Humulin R shouldn't be used during an episode of hypoglycemia (low blood sugar). Low blood sugar is a common side effect of insulin. Symptoms may include: Hunger Headache Weakness Sweating Irritability Tremors Trouble concentrating Fast heartbeat Fainting Seizures Look out for signs of low blood sugar, and carry candy or glucose tablets in case you have an episode. You may also experience signs of hyperglycemia (high blood sugar), which often include: Hunger Increased thirst Dry mouth Fruity breath odor Dry skin Blurred vision Weight loss Increased urination Drowsiness You'll need to monitor your blood sugar levels often while taking this medicine. It's important that you keep Humulin R with you at all times. Be sure to get your prescription refilled before you run out of this medicine. Don't change the brand of insulin or type of syringe you're using without first talking to your healthcare provider. They may not be interchangeable. Before taking Humulin R, tell your doctor if you have, or have ever had: Kidney or liver disease Heart failure, or other heart problems Nerve, adrenal, pituitary, or thyroid problems Eye problems caused by diabetes Allergies to medications Let your doctor know about all the medicines you're taking while using Humulin R, especially certain oral diabetes drugs, such as Actos (pioglitazon Continue reading >>

Humalog Vs Humulin R - Medhelp

Humalog Vs Humulin R - Medhelp

Common Questions and Answers about Humalog vs humulin r I have even changed the bottle just in case there was something wrong with that vial and nothing has changed. I've though of just goign to Humalog (which I use at dinner) however I like R in the morning since i dont have to give myself another injection at lunch. Anyone can help with an explanation of what could possibly be going on? I had much better control when I was using humuln n and humulin r . I am now taking lantus and novolog .I have had to increase my dosages and am still having a hard time getting control of my blood sugars. My aic is 7.8 this quarter vs 8. last quarter. should I go back to using the older drugs that gave me better control? Copyright 1994-2018 MedHelp. All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Sit Continue reading >>

Humulin R For Boluses And Humalog For Corrections

Humulin R For Boluses And Humalog For Corrections

Humulin R for boluses and Humalog for corrections Humulin R for boluses and Humalog for corrections I can't bolus with Humalog because of Gastropresis as it's action doesn't match with glucose But Humulin R suits me but it takes too long to correct spikes Can we take Humulin R for bolus and humalog for corrections Would be grateful if you could please answer my question D.D. Family T1 since 1985, MM Pump 2013, CGM 2015 I don't see why not. You'll need a Doc to write the script for the Humalog, and it may be a few hoops to get insurance to cover both. But I certainly see the logic. D.D. Family T1 since 1966, pumper since '03, transplant '08 Sure. Many moons ago I took my R & N shot in the morning (lantus was not yet available), took my humalog that I'd sort of worked out with the N peak, at dinner, and then took another shot of N at bedtime. It worked well enough at the time. If the R matches your digestion, then go for it! T1 since 1966, dialysis in 2001, kidney transplant in 02 from my cousin, pumping 03 - 08, pancreas transplant Feb 08 Continue reading >>

Insulin For Type 1 And Type 2 Diabetes

Insulin For Type 1 And Type 2 Diabetes

The different types of insulin are categorized according to how fast they start to work (onset) and how long they continue to work (duration). The types now available include rapid-, short-, intermediate-, and long-acting insulin. Injectable insulin is packaged in small glass vials (bottles) and cartridges that hold more than one dose and are sealed with rubber lids. The cartridges are used in pen-shaped devices called insulin pens. Insulin usually is given as an injection into the tissues under the skin (subcutaneous). It can also be given through an insulin pump , an insulin pen , or jet injector, a device that sprays the medicine into the skin. Some insulins can be given through a vein (only in a hospital). Research is ongoing to develop not only new forms of insulin but also insulin that can be taken in other ways, such as by mouth. Insulin lets sugar (glucose) in the blood enter cells, where it is used for energy. Without insulin, the blood sugar level rises above what is safe for the body. If the cells don't get sugar to use for energy, they try to use other nutrients in the body. When this happens, acids can build up. Too much acid production (ketoacidosis) can be serious or even life-threatening. Your body uses insulin in different ways. Sometimes you need insulin to work quickly to reduce blood sugar. Your body also needs insulin on a regular basis to keep your blood sugar in a target range. Rapid-acting and short-acting insulins reduce blood sugar levels quickly and then wear off. When you use intermediate- or long-acting insulin with rapid- or short-acting insulins, the longer acting insulin starts taking effect when the shorter acting insulin begins to wear off. For example, the long-acting insulin glargine (Lantus) starts to work within 1 to 2 hours after Continue reading >>

Types Of Insulin

Types Of Insulin

Topic Overview Insulin is used to treat people who have diabetes. Each type of insulin acts over a specific amount of time. The amount of time can be affected by exercise, diet, illness, some medicines, stress, the dose, how you take it, or where you inject it. Insulin strength is usually U-100 (or 100 units of insulin in one millilitre of fluid). Short-acting (regular) insulin is also available in U-500. This is five times more concentrated than U-100 regular insulin. Long-acting insulin (glargine) is also available in U-300. This is three times more concentrated than U-100 long-acting insulin. Be sure to check the concentration of your insulin so you take the right amount. Insulin is made by different companies. Make sure you use the same type of insulin consistently. Types of insulinfootnote 1 Type Examples Appearance When it starts to work (onset) The time of greatest effect (peak) How long it lasts (duration) Rapid-acting Apidra (insulin glulisine) Clear 10-15 minutes 1-1.5 hours 3-5 hours Humalog (insulin lispro) Clear 10-15 minutes 1-2 hours 3.5-4.75 hours NovoRapid (insulin aspart) Clear 10-15 minutes 1-1.5 hours 3-5 hours Short-acting Humulin R, Novolin ge Toronto (insulin regular) Clear 30 minutes 2-3 hours 6.5 hours Intermediate-acting Humulin N, Novolin ge NPH(insulin NPH) Cloudy 1-3 hours 5-8 hours Up to 18 hours Long-acting Lantus (insulin glargine) Clear 1.5 hours Does not apply Up to 24 hours Levemir (insulin detemir) Clear 1.5 hours Does not apply 16 to 24 hours Toujeo (insulin glargine U-300) Clear Up to 6 hours Does not apply Up to 30 hours Rapid-acting insulins work over a narrow, more predictable range of time. Because they work quickly, they are used most often at the start of a meal. Rapid-acting insulin acts most like insulin that is produced by Continue reading >>

The Abcs Of Insulin

The Abcs Of Insulin

Insulin is a naturally occurring hormone produced by the pancreas. Insulin is required to move sugar from the blood into the bodys cells, where it can be used for energy. For the symptoms of high blood sugar and low blood sugar, see Tables 1 and 2. Type 1 diabetes (T1D) is a chronic condition in which the pancreas produces little or no insulin. Only 5% of patients with diabetes have this form of the disease, according to the American Diabetes Association. Type 2 diabetes (T2D) is much more common; the risk factors are listed in online table 3. Individuals with T2D make insulin, but their bodies dont respond well to it, a condition known as insulin resistance. Treatment of T2D usually begins with dietary and lifestyle changes, as well as oral medications. Over time, as the pancreas struggles to make an adequate amount of insulin to overcome insulin resistance, patients may require insulin supplementation. Insulin therapy must be individualized and balanced with meal planning and exercise. When a patient begins using insulin to manage diabetes, the initial dose is just a starting point. Over time, insulin requirements are affected by factors such as weight gain or loss, changes in eating habits, and the addition of other medications. The need for insulin often increases, and the dose must be readjusted to meet the new requirements. Insulin is injected subcutaneously, meaning not very deep under the skin. Common injection sites include the stomach, buttocks, thighs, and upper arms. By rotating the site of injection, patients can avoid lipohypertrophy, a slight increase in the growth or size of fat cells under the skin. When lipohypertrophy occurs, a soft pillowy growth may form at the repeated-use injection site. Therefore, for reliable absorption rates and cosmetic purpo Continue reading >>

Insulin Chart

Insulin Chart

Onset of action - time period after injection that insulin will begin to work Duration of action - length of time after injection that insulin will have a measurable effect Peak effect - time after injection when insulin will have its greatest activity (effect) NOTE: Pharmacokinetic parameters are affected by age, kidney function, liver function, concomitant medications, medical conditions, and other variables. Because of this, parameters may vary widely among patients. In the U.S., most insulins cost > $150 a vial/pens with one exception; Walmart sells Novolin R, Novolin N, and Novolin 70/30 for $25 a vial * For use in HumaPen Luxura HD and HumaPen Memoir See Inhaled insulin for a complete review of Afrezza Afrezza comes in a sealed foil package with 2 blister cards inside Each blister card has 5 rows of 3 cartridges Before use, cartridge and inhaler should be at room temperature for 10 minutes Inhaler should be thrown away after 15 days Sealed foil package is good until expiration date Sealed blister cards + strips - use within 10 days SoloStar is compatible with all BD pen needles Apidra is a premeal (also called prandial) insulin Inject Apidra within 15 minutes before a meal or within 20 minutes after starting a meal Apidra is compatible with some insulin pumps UNPUNCTURED, REFRIGERATED (Vials and Pens) Inject Fiasp at the start of a meal or within 20 minutes after starting a meal KwikPen is compatible with all BD pen needles Inject Humalog within 15 minutes before a meal or immediately after a meal Humalog is compatible with some insulin pumps HumaPen Luxura HD is a reusable pen that allows dosing in 0.5 unit increments HumaPen Memoir records the time, date, and dose of the last 16 injections UNPUNCTURED, REFRIGERATED (Vials, Pens, Cartridges) UNPUNCTURED, ROOM TE Continue reading >>

Pre-meal Insulin Analogue Insulin Lispro Vs Humulin R Insulin Treatment In Young Subjects With Type 1 Diabetes.

Pre-meal Insulin Analogue Insulin Lispro Vs Humulin R Insulin Treatment In Young Subjects With Type 1 Diabetes.

Abstract The present prospective one-year randomized study was conducted to compare soluble human insulin, with a new rapid-acting human insulin analogue, lispro, with respect to postprandial glucose excursions, frequency of hypoglycaemic episodes, glucose control, and long-term safety in 39 subjects (20 females, 19 males) with Type 1 diabetes. The duration of diabetes, gender distribution, and age were similar in the two groups. The total number of hypoglycaemic episodes was significantly less (p < 0.04, Wilcoxon rank sum test) in subjects receiving insulin lispro compared with regular human insulin over the 12-month period. The 2-h postprandial glucose excursion at 1 year was also significantly less (p < 0.05, ANOVA) in the group treated with insulin lispro. The reductions in the total number of hypoglycaemic episodes and in the postprandial glucose excursion with use of insulin lispro may be beneficial for the long-term management of subjects with Type 1 diabetes. However, the greatest benefit identified by the subjects receiving insulin lispro was the greater convenience of the rapid-acting analogue. Continue reading >>

Insulin Lispro: A Fast-acting Insulin Analog

Insulin Lispro: A Fast-acting Insulin Analog

Research has established the importance of maintaining blood glucose levels near normal in patients with type 1 (insulin-dependent) diabetes mellitus. Short-acting insulin analogs are designed to overcome the limitations of regular short-acting insulins. Compared with regular human insulin, the analog insulin lispro offers faster subcutaneous absorption, an earlier and greater insulin peak and a more rapid post-peak decrease. Insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, and peak levels occur 30 to 90 minutes after administration. Duration of activity is less than five hours. Rates of insulin allergy, lipodystrophy, hypoglycemia and abnormal laboratory test results are essentially the same in patients using insulin lispro and in those using regular human insulin. The Diabetes Control and Complications Trial (DCCT)1 established the importance of maintaining near-normal blood glucose levels in patients with type 1 (insulin-dependent) diabetes mellitus. In these patients, intensive therapeutic regimens have been found to delay the onset and reduce the progression of microvascular complications by 50 to 75 percent as compared with conventional regimens. Although no large-scale investigations have been completed, smaller studies have reported similar benefits for intensive therapeutic regimens in patients with type 2 (non–insulin-dependent) diabetes.2 Primary care physicians provide medical care for 75 percent of children and 90 to 95 percent of adults with diabetes.3 Regardless of the type of diabetes, improved glycemic control often can be achieved with individualized tools for patient self-management, carefully formulated nutrition plans and the use of alternative insulin regimens.4 Overview of Insulin Insulin is necessary Continue reading >>

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