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Humalog Mix 50 / 50 Price In India

Lilly Launches Humalog(r) Mix50/50(tm) Insulin In United States

Lilly Launches Humalog(r) Mix50/50(tm) Insulin In United States

Lilly Launches Humalog(R) Mix50/50(TM) Insulin in United States Lilly Launches Humalog(R) Mix50/50(TM) Insulin in United States Lilly Launches Humalog(R) Mix50/50(TM) Insulin in United States 11.9 KB Feb 07, 2006 /PRNewswire-FirstCall via COMTEX News Network/ -- Different people with diabetes have different insulin needs, and today Eli Lilly and Company (NYSE: LLY) announces the launch of a new pre-mixed insulin, Humalog(R) Mix50/50(TM) (50% insulin lispro protamine suspension, 50% insulin lispro injection (rDNA origin)). Humalog Mix50/50 is for use in patients with diabetes to control high blood sugar and is available in an easy-to-use pen delivery device. Humalog Mix50/50 is designed to provide blood sugar control between meals but also includes a higher percentage of rapid-acting insulin for people with diabetes who need more insulin control at mealtime. The Humalog component starts lowering blood sugar more quickly than regular human insulin, allowing for convenient dosing immediately before a meal (within 15 minutes). Humalog Mix50/50 provides doctors with an additional tool to help their patients better manage blood sugar after meals. "Lilly is the leader in diabetes therapies and is pleased to add to its robust portfolio with the launch of Humalog Mix50/50," said Ron Hoven, diabetes care marketing director, Eli Lilly and Company. "Some people with diabetes try to make an effort but are busy and don't always eat balanced meals. For those who need improved blood sugar control at mealtime while also balancing their blood sugar between meals, Humalog Mix50/50 may provide a new solution." Humalog Mix50/50 is available now and comes in a prefilled pen. Humalog or Humalog Mix50/50 is contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog o Continue reading >>

Humalog Mix-50 Kwikpen Product Information | The Filipino Doctor

Humalog Mix-50 Kwikpen Product Information | The Filipino Doctor

For the treatment of patients w/ DM who require insulin for the maintenance of normal glucose homeostasis. For dosage information of prescription medicine, please consult with your doctor. Transferring to another type or brand, changes in strength, species, &/or method of manufacture of insulin, uncorrected hypoglycemic or hyperglycemic reactions, use of inadequate dosages or discontinuation of treatment, renal or hepatic impairment, illness or emotional disturbances, increased physical activity or change of usual diet, administration to childn <12 yrs old only in case of an expected benefit compared to regular insulin. Pregnancy Risk Category is B. Pregnancy Risk Category by the US FDA: Close A - Adequate and compelling studies in humans do not show any evidence that the product poses a risk to the baby in the womb. B - Adequate and compelling studies in animals do not show a risk to the baby, but there are not enough compelling studies in humans. Otherwise, animal studies show a risk but studies on humans do not show any. C - Adequate and compelling studies in animals show a risk to the baby, but there are not enough compelling studies in humans. However, the product may be used in pregnant women in certain situations despite potential risks. D - Adequate and compelling studies in humans show a risk to the baby. However, the product may be used in pregnant women in certain situations despite the potential risks. X - Adequate and compelling studies in animals or humans show a risk to the baby in the womb. Also, use or experience in humans shows a risk. The danger of using the product in pregnant women clearly outweighs its benefits. Oral contraceptives, corticosteroids, thyroid replacement therapy, danazol, beta-2 stimulants, oral hypoglycemics, salicylates, sulpha an Continue reading >>

National Pharmaceutical Pricing Authority

National Pharmaceutical Pricing Authority

F. NO. 8 (7)/2007/DP/NPPA-Div.II GOVERNMENT OF INDIA MINISTRY OF CHEMICALS AND FERTILIZERS NATIONAL PHARMACEUTICAL PRICING AUTHORITY NEW DELHI, DATED THE 14/02/2007 ORDER In exercise of the powers, conferred by sub-paragraph (1)/(2)/(4) of paragraph 8 of the Drugs (Price Control) Order, 1995, read with No. S.O. 637(E) dated the 4th September, 1997 issued by the Government of India in the Ministry of Chemicals and Fertilizers, the National Pharmaceutical Pricing Authority hereby fixes/revises the prices as specified in column (5) of the Table hereto annexed as the retail price/revised retail price, exclusive of excise duty, sales taxes/VAT and local taxes, if any, in relation to each of the formulations specified in the corresponding entry in column (2) of the said Table with pack size specified in the corresponding entries in column (3) thereof; TABLE Sl. No. Name of the Formulation Pack Size Existing Retail Price (Rs.) Retail Price without Excise Duty, Sales Tax/VAT and Local Tax, if any (Rs.) 1 Monocomponent Insulin Humalog 100 IU/ml (Insulin Lispro ) Each ml of Insulin Lispro contains 100 IU (3.5mg) Insulin Lispro ( r- DNA origin) as active ingredient, Batch No. A263524, Qty.26770 cartridges 3ml Cartridge 419.25 414.46 2 Monocomponent Insulin Humalog Mix 50 - 100 IU/ml 50% Insulin Lispro and 50% Insulin Lispro Protamine suspension, r - DNA origin Batch No. - A257892 / Qty. 11,225 cartridges 3ml Cartridge 455.35 441.10 3 Monocomponent Insulin Huminsulin Regular 100 IU/ml (Insulin Human Injection) Batch No. - A257871 / Qty. 7500 Cartridge 3ml Cartridge 208.94 221.85 4 Monocomponent Insulin Humalog Pen 100 IU/ml (Insulin Lispro ) Each ml of Insulin Lispro contains : 100 IU (3.5mg) Insulin Lispro ( r- DNA origin) as active ingredient, Batch No. A253908, Qty. 9620 Disposa Continue reading >>

Buy Humalog Mix 50 Inj 3ml*5, Eli Lilly Price & Side Effects

Buy Humalog Mix 50 Inj 3ml*5, Eli Lilly Price & Side Effects

BUY HUMALOG MIX 50 INJ 3ML*5, Eli Lilly PRICE & SIDE EFFECTS Buy HUMALOG MIX 50in the INJ form.HUMALOG MIX 50 priceis 1920 INR, USD32.2627451.HUMALOG MIX 50 side effectsare because of Anatomical Therapeutic action which we can find in its atc code. HUMALOG MIX 50 INJ dosages specified by physician as.HUMALOG MIX 50 N.I. 3ML*5 uses are in various complications related to ATA (anatomical therapeutic action).Approved Universal name by FDA (Generic Name) for the drug isN.I.. Legal Availability for public By prescription. Buy Related Medicine Price, Side Effects: is available in India and sold at almost every medical store, you can not buy HUMALOG MIX 50 without prescription. You can Buy it from Eli Lilly. Physical form sold is INJ. In international market you can buy HUMALOG MIX 50 INJ N.I. in different brands and strengh, Eli Lilly sales it in India. You can notbuy HUMALOG MIX 50 without prescription. You canbuy HUMALOG MIX 50 onlinealso from Eli Lilly. To buy HUMALOG MIX 50 online you need prescription. To buy HUMALOG MIX 50 online with credit card you may need a prescription from physicians, several websites sales online with active ingredients N.I.. TO buy HUMALOG MIX 50 online at low price you should consider different brands of the generic ingredients. For fast delivery youn may consider Eli Lilly. You can buy it online from Eli Lilly India. HUMALOG MIX 50 buy rate keep fluctuating with time and demand and this rate defines the Market price of the brand. Historical data of Drug demand fluctuation with years is given here. Increasing %age of Buy online rateBuy year Rise in HUMALOG MIX 50 sales from 2010 to 2016 HUMALOG MIX 50 is legally available only with a prescription, You will need a prescription from Authorized physician in India to buy anywhere. Online stores al Continue reading >>

Buy Humalog Mix 50/50cartridges5 X 3 Mlpk Online

Buy Humalog Mix 50/50cartridges5 X 3 Mlpk Online

Injection site irritation, such as redness, itching and swelling in patients is also common. This usually settles in a few days to a few weeks. This may not be due to the Humalog 50/50 mixture and may be related to other things such as contaminants in a skin cleansing product or an improper injection technique. Less common side effects may include hypokalemia, which occurs when there is an appearance of dangerously low levels of potassium (K+) in the blood, and lipodystrophy, which is a disorder of fat production, specifically lipoatrophy, the localized loss of fat tissue. Serious side effects may also include anaphylaxis (a severe allergic reaction) and other hypersensitivity or allergic reactions. Prior to first use, Humalog 50/50 Cartridges should be stored in a refrigerator between 2 and 8C, be careful not to freeze the insulin. Be sure to read the patient information leaflet provided by your doctor before you begin using Humalog 50/50 and each time you get a refill. The suspension mixture should be white. It should be administered subcutaneously (under the skin). You must be careful not to hit any major blood vessels when injecting your insulin. Humalog 50/50 should be given between 15 minutes before a meal, or up to 20 minutes after you have begun eating. Despite these suggestions, always follow your doctors instructions above all others when taking this medication. Always carefully follow your doctors directions about your dosage, as well. Specifically, on which insulin to use, how much, and when and how often to inject it. Each case of diabetes is unique and your doctor will likely personalize your dosing schedule for you, specifically. Your dose and schedule may be affected by changes in the food you eat, your activity level, or your schedule at work. Other fa Continue reading >>

Lilly Announces Program To Provide Insulin At Discounted Prices

Lilly Announces Program To Provide Insulin At Discounted Prices

Lilly Announces Program to Provide Insulin at Discounted Prices Starting January 1, people who pay the highest out-of-pocket prices for insulin, such as those who pay full retail price at the pharmacy, may directly benefit from 40 percent discount Dec 13, 2016, 06:30 ET from Eli Lilly and Company Eli Lilly and Company logo. (PRNewsFoto, Eli Lilly and Company) (PRNewsFoto/ELI LILLY AND COMPANY) Eli Lilly and Company logo. (PRNewsFoto, Eli Lilly and Company) (PRNewsFoto/ELI LILLY AND COMPANY) INDIANAPOLIS, Dec. 13, 2016 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY ) today announced that people who use Lilly insulin will be able to access discounted prices for their purchases starting January 1, 2017 via mobile and web platforms hosted by Blink Health. The discounts, provided by Lilly through a partnership with Express Scripts (NASDAQ: ESRX ), may reduce costs for people who pay full retail prices at the pharmacy, such as those who have no insurance or are in the deductible phase of their high-deductible insurance plans. Changes in insurance benefit design have increased the cost of insulin for some people. While discounts and rebates paid by manufacturers make insulin affordable for most people, they don't directly help the uninsured or people in the deductible phase of their high-deductible plans. And while some high-deductible plans exempt insulin from the deductible phase, others require people to pay most or all of the retail price until the deductible is met meaning these people don't fully benefit from rebates when they visit the pharmacy. By using the Blink Health platforms, people who pay full price for most Lilly insulins may save 40 percent. This discount program will be the first time branded medicines will be discounted via the Blink Health platform, whic Continue reading >>

National Pharmaceutical Pricing Authority : Price Notification

National Pharmaceutical Pricing Authority : Price Notification

NATIONAL PHARMACEUTICAL PRICING AUTHORITY In exercise of the powers, conferred by sub-paragraph (1)/(2)/(4) of paragraph 8 of the Drugs (Price Control) Order, 1995, read with No. S.O. 637(E) dated the 4th September, 1997 issued by the Government of India in the Ministry of Chemicals and Fertilizers, the National Pharmaceutical Pricing Authority hereby fixes/revises the prices as specified in column (7) of the Table hereto annexed as the retail price/revised retail price, exclusive of local tax if any, in relation to each of the formulations specified in the corresponding entry in column (2) of the said Table with pack size specified in the corresponding entries in column (3) thereof; Retail Price without Excise Duty Revised Retail Price with Excise Duty (Rs.) Batch No. - FF5T34E/ Qty.100000 Cartridges 100 IU (3.5mg) Insulin Lispro (r-DNA Origin) Batch No. - FF6C55E / Qty.9000 Cartridges Batch No. - FF5Z74D / Qty.11500 Cartridges Batch No. - FF6B71D / Qty.13300 Cartridges 50% Insulin Lispro and 50% Insulin Lispro Batch No. - FF6B85D / Qty.5000 Cartridges Lispro protamine suspoension, r-DNA origin Batch No. - FF5X28D / Qty.250 Disposable Pens Batch No. - FF5X27C / Qty.250 Disposable Pens Lispro protamine suspoension, r-DNA origin Batch No. - FF5X74C / Qty.250 Disposable Pens 2. This order shall be applicable if the manufacturer of the formulation specified in column (2) of the Table above has complied with the requirements, if any, of (a) the Drugs and Cosmetics Act, 1940 (23 of 1940) and the rules made thereunder; and (b) the Industries (Development and Regulation) Act, 1951 (65 of 1951) as amended from time to time. 3.(a) The prices fixed/revised is the Maximum Retail Prices (inclusive of excise duty and exclusive of local taxes, if any) for the specified pack and pack Continue reading >>

Humalog Mix 50/50 Prices, Coupons And Patient Assistance Programs

Humalog Mix 50/50 Prices, Coupons And Patient Assistance Programs

Important: When there is a range of pricing, consumers should normally expect to pay the lower price. However, due to stock shortages and other unknown variables we cannot provide any guarantee. The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions. Please note: This is a drug discount program, not an insurance plan. Valid at all major chains including Walgreens, CVS Pharmacy, Target, WalMart Pharmacy, Duane Reade and 65,000 pharmacies nationwide. Humalog Mix 50/50 offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office. There are currently no Manufacturer Promotions that we know about for this drug. Patient Assistance Programs for Humalog Mix 50/50 Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program. There are currently no Patient Assistance Programs that we know about for this drug. More about Humalog Mix 50/50 (insulin lispro / insulin lispro protamine) Continue reading >>

Humalog Mix 50 Cartridges : Uses, Price, Benefits, Side Effects, Reviews | Saveonmedicals

Humalog Mix 50 Cartridges : Uses, Price, Benefits, Side Effects, Reviews | Saveonmedicals

Retailer: ANN Pharma and Food Solutions Pvt. Ltd. Insulin is a natural hormone made by body which regulates the blood sugar levels in body. It helps in maintaining sugar levels in blood going either too high or too low. Man-made insulin does the work of human insulin when human body stops making enough insulin. Side Effects Of HUMALOG MIX 50 CARTRIDGES Redness or itching in the area of injection. Please inform your doctor immediately if you experience any signs of low potassium in blood. Contraindications Of HUMALOG MIX 50 CARTRIDGES Please inform your doctor if you have any of the following conditions: Diabetes mellitus (type 2) is characterized by high blood sugar, relative lack of insulin and insulin resistance. It is a long term metabolic disorder. Long term complications of diabetes are diabetic retinopathy, resulting in blindness, heart disease, strokes, kidney failure, poor flow of blood in limbs requiring amputation. Symptoms Treated With HUMALOG MIX 50 CARTRIDGES What Are The Symptoms Of Diabetes Mellitus Type 2 Common symptoms include increased thirst, frequent urination, and unexplained weight loss. Some patients may also feel increased hunger, feeling of tiredness, and sores that do not heal. Causes of diseases where HUMALOG MIX 50 CARTRIDGES is used What Are The Causes Of Diabetes Mellitus Type 2 Type 2 diabetes mainly occurs because of obesity and lack of exercise. Some people are at more risk genetically than others. Type 2 diabetes can be prevented by regular exercise, maintaining normal weight and proper diet. Worst Foods With HUMALOG MIX 50 CARTRIDGES What Are The Worst Foods For Diabetes Mellitus Type 2 Fruits like mango, bananas, melon, peaches, nectarines What Are The Symptoms Of Diabetes Mellitus Type 2 Common symptoms include increased thirst, fr Continue reading >>

Welcome To The Humalog® Family Of Insulins.

Welcome To The Humalog® Family Of Insulins.

Humalog® is used to treat people with diabetes for the control of blood sugar. Humalog® Mix75/25™(75% insulin lispro protamine suspension and 25% insulin lispro injection) and Humalog® Mix50/50™(50% insulin lispro protamine suspension and 50% insulin lispro injection) are used to treat adults with diabetes for the control of high blood sugar. Do not share your Humalog, Humalog Junior, Humalog Mix75/25, or Humalog Mix50/50 KwikPens, cartridges, reusable pen compatible with Lilly 3 mL cartridges, or syringes with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them. The Humalog contained in the Humalog U-200 KwikPen should ONLY be injected with the Humalog U-200 KwikPen. Do NOT withdraw Humalog U-200 from the pen using a syringe. It could result in an overdose causing severe low blood sugar which may put your life in danger. Do not change the insulin you use without talking to your healthcare provider. Changes may make you more likely to experience low or high blood sugar. Changes should be made cautiously under the supervision of your healthcare provider. When used in a pump, do not mix or dilute Humalog U-100 with any other insulin or liquid. Do NOT use Humalog U-200, Humalog Mix75/25 or Humalog Mix50/50 in a pump. These insulins start working faster than other insulins that contain regular human insulin. You should take Humalog within fifteen minutes before eating or right after eating a meal. You should take Humalog Mix75/25 and Humalog Mix50/50 within fifteen minutes before eating. Do not use Humalog Mix75/25 or Humalog Mix50/50 if they have solid particles or clumps in them. Humalog Mix75/25 and Humalog Mix50/50 should be mixed carefully before each use and should be cloudy or mi Continue reading >>

Humalog Mix50 Kwikpen Pen(prefilled) 1x3ml

Humalog Mix50 Kwikpen Pen(prefilled) 1x3ml

HUMALOG MIX50 KWIKPEN PEN(PREFILLED) 1x3ML HUMALOG MIX50 KWIKPEN PEN(PREFILLED) 1x3ML 5% NMSCash / Wallet* - on all Full Pre-Paid Orders! 100% NMS SuperCash* (max Rs.3000) - on all full Pre-Paid Orders! Note: This product cannot be returned for a refund or exchange. Please note, before you can choose the low cost generic option, please ask your doctor to add the generic drug to your prescription. Insulin Lispro is used for the treatment of type 1 and type 2 diabetes mellitus. Insulin Lispro may also be prescribed for other conditions as determined by the doctor. Insulin Lispro + Insulin Lispro Protamine combination belongs to the class of drugs called as anti-diabetics. This combination lowers the blood glucose levels by stimulating the uptake of glucose by skeletal cells and fat tissues and by inhibiting the glucose production by the liver. The dosage and the drug form depend on the age, weight and medical condition of an individual. Use Insulin Lispro as prescribed by your doctor. Insulin Lispro is available as an injection and should be administered as per the instructions provided by the doctor. For type 1 diabetes, Insulin Lispro should be administered 15 minutes before a meal. For type 2 diabetes, Insulin Lispro should be administered 15 minutes before or after a meal. Avoid injecting the drug into a skin area that is swollen and red. If you miss a dose of Insulin Lispro, please consult the doctor. What are the drugs that interact with Insulin Lispro? Drugs that interact with Insulin Lispro include the following: This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions. What are the side effects of Insulin Lispro? The following are the most common side effects of Insulin Lispro: The following a Continue reading >>

Humalog Mix 50/ 50 Vials Uses

Humalog Mix 50/ 50 Vials Uses

Humalog Mix 50/ 50 vials contains a mixture ofHumalog Mix 50/ 50 vials. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin lispro (Humalog Mix 50/ 50 vials) is a fast-acting insulin. Insulin lispro (Humalog Mix 50/ 50 vials) protamine is an intermediate-acting insulin. This combination insulin starts to work within 10 to 20 minutes after injection, peaks in 2 hours, and keeps working for up to 24 hours. Humalog Mix 50/ 50 vials is used to improve blood sugar control in adults with. This medicine may be used for type 1 or type 2 diabetes. Humalog Mix 50/ 50 vials may also be used for purposes not listed in this medication guide. An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician. Humalog Mix75/25, a mixture of 75% Insulin lispro (Humalog Mix 50/ 50 vials) protamine suspension and 25% Insulin lispro (Humalog Mix 50/ 50 vials) injection, (rDNA origin), is indicated in the treatment of patients with diabetes mellitus for the control of hyperglycemia. Humalog Mix75/25 has a more rapid onset of glucose-lowering activity compared with Humulin 70/30 while having a similar duration of action. This profile is achieved by combining the rapid onset of Humalog with the intermediate action of Insulin lispro (Humalog Mix 50/ 50 vials) protamine suspension. How should I Continue reading >>

Humalog Mix 50 Side Effects, Price, Pharmacology & Alternatives | Medicine India

Humalog Mix 50 Side Effects, Price, Pharmacology & Alternatives | Medicine India

Redness, swelling, or itching at the site of inj Home Delivery for HUMALOG MIX 50 in Your City Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including humalog mix 50. However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for humalog mix 50 and other medicines and health products. Home delivery services for humalog mix 50 may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order. Please be aware that you should take humalog mix 50 only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for humalog mix 50 before they complete the sale. You can get this information while placing the order for humalog mix 50 with the pharmacy. If the pharmacy that's willing to deliver medicines to your home doesn't have humalog mix 50 in stock, you can ask for one of the alternative medicines for humalog mix 50 . Alternatively, you can ask the pharmacist to recommend good options for the Biphasic Insulin Lispro generic medicine (which is what humalog mix 50 essentially is). Continue reading >>

Eli Lilly Launches Humalog Mix Variants

Eli Lilly Launches Humalog Mix Variants

Last Updated at February 25, 2013 23:28 IST LML to post net profit in Q4FY06: Singhania Eli Lilly & Company (India) Private Limited, a 100 per cent subsidiary of Eli Lilly & Company of USA, has launched three different variations of "Humalog Mix", an insulin analog mixture for treating diabetes, here on Wednesday. According to company's chairman and managing director, Rajiv Gulati, Humalog, available at Rs 389 per cartridge consisting of 300 units, absorbs quickly and starts working within minutes to lower blood sugar. The three different variations of Humalog are insulin lispro, mix 25 and mix 50. "Eli Lilly is the only company in India to introduce Humalog mix 50," Gulati said, adding that the company was planning to launch one new product every year. So far, it had launched eight products. The company's turnover last year stood at Rs 150 crore. Eli Lilly of USA, a Fortune-500 company, had set up its Indian outfit initially as a 50:50 joint venture with Ranbaxy. In August 2001, it had bought over the 50 per cent equity of Ranbaxy to make it a wholly-owned subsidiary. First Published: Thu, August 11 2005. 00:00 IST Copyrights 2018 Business Standard Private Ltd. All rights reserved. Business Standard is happy to inform you of the launch of "Business Standard Premium Services" As a premium subscriber you get an across device unfettered access to a range of services which include: Access Exclusive content - articles, features & opinion pieces Weekly Industry/Genre specific newsletters - Choose multiple industries/genres Access to 17 plus years of content archives Set Stock price alerts for your portfolio and watch list and get them delivered to your e-mail box End of day news alerts on 5 companies (via email) NEW: Get seamless access to WSJ.com at a great price. No addit Continue reading >>

Humalog 50-50

Humalog 50-50

HUMALOG® Mix50/50™ 50% Insulin Lispro Protamine Suspension and 50% Insulin Lispro Injection (Rdna Origin) 100 Units Per Ml (U-100) DESCRIPTION Humalog® Mix50/50™ [50% insulin lispro protamine suspension and 50% insulin lispro injection, (rDNA origin)] is a mixture of insulin lispro solution, a rapid-acting blood glucose-lowering agent and insulin lispro protamine suspension, an intermediate-acting blood glucose-lowering agent. Chemically, insulin lispro is Lys(B28), Pro(B29) human insulin analog, created when the amino acids at positions 28 and 29 on the insulin B-chain are reversed. Insulin lispro is synthesized in a special non-pathogenic laboratory strain of Escherichia coli bacteria that has been genetically altered to produce insulin lispro. Insulin lispro protamine suspension (NPL component) is a suspension of crystals produced from combining insulin lispro and protamine sulfate under appropriate conditions for crystal formation. Insulin lispro has the following primary structure: Insulin lispro has the empirical formula C257H383N65O77S6 and a molecular weight of 5808, both identical to that of human insulin. Humalog Mix50/50 vials and Pens contain a sterile suspension of insulin lispro protamine suspension mixed with soluble insulin lispro for use as an injection. Each milliliter of Humalog Mix50/50 injection contains insulin lispro 100 units, 0.19 mg protamine sulfate, 16 mg glycerin, 3.78 mg dibasic sodium phosphate, 2.20 mg Metacresol, zinc oxide content adjusted to provide 0.0305 mg zinc ion, 0.89 mg phenol, and Water for Injection. Humalog Mix50/50 has a pH of 7.0 to 7.8. Hydrochloric acid 10% and/or sodium hydroxide 10% may have been added to adjust pH. Continue reading >>

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