The Hpv Vaccine And Autoimmunity: Reviewing The Research
The HPV Vaccine and Autoimmunity: Reviewing the Research Editor's Note: Medscape asked Paul Offit, MD, to provide more detailed commentary in response to the letter to the editor he wrote, Paul Offit Responds to News About HPV Vaccine 'Syndrome' . Our goal is to offer more information to health professionals about what the evidence says regarding human papillomavirus (HPV), vaccine safety, and adverse events. HPV Vaccine and Adverse Effects: A Focus on the Research In 2006, the Centers for Disease Control and Prevention (CDC) recommended the HPV vaccine for girls aged 11-13 years. In 2010, the CDC extended its recommendation to include adolescent boys. Since licensure, more than 200 million doses of the vaccine have been distributed globally. Because the vaccine has been given to millions of people, strokes, anaphylaxis, autoimmune diseases, venous thromboembolism, and adverse pregnancy outcomes have, on rare occasion, occurred following vaccination. To determine whether these events are causally or coincidentally associated with receipt of the HPV vaccine, investigators have studied large numbers of people who did or did not receive the vaccine. To determine whether these events are causally or coincidentally associated with receipt of the HPV vaccine, investigators have studied large numbers of people who did or did not receive the vaccine. To address concerns over news reports or published case series of autoimmune disorders appearing after HPV immunization, I will focus on studies related to the association between HPV vaccine and autoimmune disorders in this review. In 2011, Chao and colleagues[ 1 ] at the Kaiser Permanente Vaccine Study Center in Oakland, California, evaluated 189,629 women of all ages who had received at least one dose of the quadrivalent HPV va Continue reading >>
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Fda Warning: Popular Diabetes Drug Linked To Cancer
Written by Amy Tenderich on June 15, 2011 Health professionals reportedly are receiving letters this week alerting them to an FDA warning just issued about risks of thyroid cancer and pancreatitis associated with the popular type 2 diabetes drug liraglutide (Victoza). Yikes! According to MSM reports , the evidence was found in mice, and it's unclear if the serious risks translate to humans but there was enough concern to issue the follow warning: "Clinical trials have shown more cases of pancreatitis with liraglutide than with other diabetes drugs, so the FDA recommended patient monitoring after starting liraglutide or raising the dosage, for symptoms such as persistent severe abdominal pain. This pain can sometimes radiate to the back and is accompanied by vomiting. Liraglutide should be immediately stopped if pancreatitis is suspected and not restarted if the disease is confirmed. The FDA urged a cautious approach in patients with a history of pancreatitis. The agency also highlighted the contraindication for liraglutide in patients with a personal or family history of medullary thyroid cancer or a personal history of multiple endocrine neoplasia syndrome type 2." Seeing as how the 'Mine has become home to the unofficial leading chat forum for Victoza users, we thought you all might like to know! We'll be posting an alert there as well, of course. This content is create for Diabetes Mine, a consumer health blog focused on the diabetes community. The content is not medically reviewed and doesn't adhere to Healthline's editorial guidelines. Continue reading >>
Juvenile Diabetes And Vaccination: New Evidence For A Connection
In the fall of 1997, the Centers for Disease Control confirmed that the number of Americans living with diabetes has skyrocketed in the past 40 years with a record sixfold increase in this chronic disease since 1958. It is estimated that nearly 16 million Americans are suffering with diabetes and 5 million more may have it but not know it. Over the past four decades, intensive national mass vaccination campaigns have dramatically increased vaccination rates among American children who now are getting 34 doses of 10 different viral and bacterial vaccines before they enter kindergarten. Recent published data in the medical literature suggest increasing numbers of childhood vaccines may be playing a role in the big jump in the number of cases of juvenile diabetes. The most frequent kind of diabetes is diabetes mellitus, a chronic degenerative disease caused when the pancreas either fails to produce a protein hormone called insulin or the body's cells are resistant to the action of insulin. Without insulin, the body cannot process and use glucose, a blood sugar which is a chief source of energy for living organisms and is found in certain foods like fruit. If the body's cells have become resistant to insulin, glucose cannot be moved from the blood to cells in order to be transformed into energy. There are two types of diabetes mellitus: Type I, called insulin-dependent juvenile diabetes, and Type II, called adult-onset diabetes. Type I Diabetes - Type I diabetes, also called insulin-dependent diabetes mellitus (IDDM), occurs mostly in children and young adults. Five to 10 percent of those diagnosed with diabetes are Type I diabetics. In Type I diabetes, the body cannot produce insulin. This causes glucose to build up in the bloodstream and be secreted from the body in the Continue reading >>
Current Research Into Cures For Type-1 Diabetes
Current Research into Cures for Type-1 Diabetes News and updates on potential cures for type-1 diabetes, that are in human (or clinical) trials. There are 14+ studies showing that vaccines do not increase the chance of getting type-1 diabetes, and I've posted that list in the past. However, most of those studies were done before HPV vaccines were developed, so this posting focuses on HPV vaccines. This posting covers the two HPV vaccines in common use in the US: Cervarix (made by GlaxoSmithKline) and Gardasil (made by Merck). A vast amount of background information on HPV and these vaccines is available on Wikipedia: Including HPV prevalence, death rates, etc. Studies on HPV Vaccines and Type-1 Diabetes It is important to remember that these vaccines are typically given to girls (and increasingly boys) at about 10-14 years old. This is "prime time" for type-1 diabetes diagnosis as well. So we should all expect stories that talk about someone who got an HPV vaccine and then came down with type-1 diabetes a few weeks later. Occasionally, we'll even hear about stories where the person was diagnosed with type-1 diabetes the day of the vaccine, or maybe just a day or two later. Because of blind bad-luck, and the relative number of people given the vaccine and diagnosed at the same time, you will see a few that overlap. But the important question is this: do people who get HPV vaccines get type-1 diabetes at a higher rate, than those who don't? A very large study was published in 2012, which looked at Gardasil and autoimmune diseases. It covered 190,000 people, and was done by an insurance company. Type-1 diabetes was one of the diseases they looked for specifically. Here is the summary from the news coverage (bolding added): They found no increase in any of 16 autoimmune di Continue reading >>
Causes Of Type 1 Diabetes
Tweet Type 1 diabetes belongs to a group of conditions known as autoimmune diseases. Autoimmune diseases are when the body incorrectly identifies its own useful cells as an attacking organism. In type 1 diabetes, it is the beta cells in the pancreas which produce insulin that are wrongfully targeted and killed off by specific antibodies created by the body’s immune system. Researchers have been investigating what may cause the immune system to act in this way but to date researchers have theories but no concrete proof. Genetic predisposition Researchers have uncovered a number of genetic regions that are linked closely with type 1 diabetes. Each of these is denoted with a name such as IDDM1. At least 18 different regions have been discovered and some of the genetic areas include an increased susceptibility for other autoimmune diseases such as rheumatoid arthritis and coeliac disease. Whilst genetics offers clues as to why some people are more susceptible to type 1 diabetes, it doesn’t explain why some people with these genes develop type 1 diabetes and why others with these genes don’t. For example, having an identical twin with type 1 diabetes gives you a statistically higher risk but it doesn’t necessarily mean you will develop the condition. Genetics does not explain either why people will develop type 1 diabetes at different ages. Type 1 diabetes is most commonly diagnosed in 10 to 14 year olds but can be diagnosed at any age. Read more on diabetes and genetics Type 1 diabetes triggers Researchers have hypothesised that whilst some people are have a genetic predisposition to type 1 diabetes, there is likely to be an environmental factor that triggers the initial development of type 1 diabetes. Some of the possible triggers that have been suggested include: Continue reading >>
Us Vaccine Court Pays $6 Million To Gardasil Victims, Most Claims Not Yet Settled
US vaccine court pays $6 million to Gardasil victims, most claims not yet settled This new information from the government shows that the serious safety concerns about the use of Gardasil have been well-founded, said Judicial Watch President Tom Fitton. Public health officials should stop pushing Gardasil on children. ******************************************************************************** Documents Obtained by Judicial Watch Reveal 200 Claims Filed with HHS for HPV Vaccine Injuries and Deaths, 49 Compensated Documents Reveal that the National Vaccine Injury Compensation Program (VICP) has Paid Out Nearly $6 million in Claims to Victims of Controversial HPV (human papillomavirus) Vaccine, including Families of Two Dead (Washington, DC) Judicial Watch announced today that it has received documents from the Department of Health and Human Services (HHS) revealing that its National Vaccine Injury Compensation Program (VICP) has awarded $5,877,710 dollars to 49 victims in claims made against the highly controversial HPV (human papillomavirus) vaccines. To date 200 claims have been filed with VICP, with barely half adjudicated. The documents came in response to a February 28, 2013, Judicial Watch lawsuit against HHS to force the department to comply with a November 1, 2012, Judicial Watch Freedom of Information Act (FOIA) request ( Judicial Watch v. U.S. Department of Health and Human Services (No. 1:13-cv-00197)). On March 12, 2013, The Health Resources and Services Administration (HRSA), an agency of HHS, provided Judicial Watch with documents revealing the following information: Only 49 of the 200 claims filed have been compensated for injury or death caused from the (HPV) vaccine. Of the 49 compensated claims 47 were for injury caused from (HPV) vaccine the addit Continue reading >>
Gardasil: The Journey No One Should Take
Gardasil: the journey no one should take Hospital Bills: $2 million after Gardasil I write this story hoping it helps save at least one girl; then our journey will not have been in vain. I will barely touch the tip of the iceberg; so much has happened over these past 4-5 years. It has been a whirlwind and like a whirlwind an unwelcome event. Stephanie was 23 years old at the time of her 1st Gardasil injection. As most young adults, she was working, had her own health insurance and took responsibility for her health and medical decisions. She had been a Type I diabetic since age 10 and knew the importance of taking care of herself. At her regular check up, the doctor said she needed to get this NEW vaccine for humanpapilloma virus (HPV). So our journey began. Steph received her first shot in June 2008; the second in October 2008. The night of her second vaccine, Stephanie was admitted to the intensive care unit with an acute respiratory problem and sky rocketing blood sugars. The 3rd injection was in December 2008. Early in 2009, Stephanie took a trip to Mexico. On the way back she experienced uncontrollable vomiting, headaches and body aches. Once again she was hospitalized. Thinking she may have picked up something while in Mexico, we pressed the hospital and doctors to check for parasites and pathogens. All tests came back negative. She was hospitalized over and over again with the same symptoms. Test after test revealed nothing. Finally she received a diagnosis of gastro paresis, thought to be a result of her diabetes. Her body was also full of yeast. One gastric empting test came back inconclusive, another came back slow. Here is the clincher; we did not give any thought to the vaccine because we did not know she had the vaccine. It was not until we started realizi Continue reading >>
Vaccines Cause Diabetes Another Myth Refuted And Debunked
Vaccines cause diabetes another myth refuted and debunked If you cruise around the internet, engaging with the antivaccination cult (not recommended), you will pick up on their standard tropes, lies, and other anti-science commentaries. One that has always bothered me, not because that it was a lie, but because I had enough evidence floating in my brain that I was wondering if it were truethat vaccines cause diabetes, especially the Type 1 version. A lot of the vaccine deniers believe that vaccines cause a lot of everything and several claims that vaccines cause Type 1 diabetes (or here ), based on little evidence.As far as I can tell, this myth is based on the research fromJ. Barthelow Classen, M.D., who has pushed the idea that vaccines cause type 1 diabetes, through some magical process that has never been supported by other independent evidence . In another example of the antivaccination worlds cherry picking evidence to support their a priori conclusions, they ignore the utter lack of plausibility supporting any link between vaccines and Type 1 diabetes. At best, Classenhas cherry-picked statistics to support his predetermined conclusions, comparing apples to oranges with health data from different countries, and misrepresenting studies to back his claim . Moreover, Classen seems to come to his beliefs based on population-wide correlations that rely on post hoc fallacies , rather than actually showing causality between vaccines and diabetes. Its like finding that a 5% increase in consumption of Big Macs is correlated with Republican wins in elections. They may happen at the same time, but it would take a laughable series events to show any relationship. Its going to get a bit science-y in this section. Sorry about that, but diabetes is complicated, it never can be Continue reading >>
Daughter Diagnosed With Type1 Within A Couple Of Weeks Of Gardasil Vaccine.
daughter diagnosed with type1 within a couple of weeks of Gardasil vaccine. Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. daughter diagnosed with type1 within a couple of weeks of Gardasil vaccine. Hi there, since my daughter was diagnosed with type1 diabetes last year I have suspected the Gardasil vaccine which she had a couple of weeks before hand may have triggered her immune system to turn on itself. I know that even if I find out it was the cause it won't turn back the clock and make it go away but I want to know why this has happened to her.Has anyone had the same experience with Gardasil or know of someone who has. I have repeatedly mentioned it to drs but I suppose they are not going to believe that a vaccine could do this. It is 'possible' (as T1 is an autoimmune condition) but unlikely. I think something like 40 million people have received the vaccine, which means that if the virus was a significant trigger then we would see far more cases. Look at it this way. Current thinking is that T1 is caused by a combination of genetic make-up and a trigger infection. If in this case it was the Gardasil, even if your daughter had avoided the vaccine she would have almost certainly developed another trigger infection anyway. Bear in mind that the vast majority of vaccine scares are influenced highly by the screw-ups from Dr. Andrew Wakefield, who essentially forged research to discredit MMR, while investing in a patent for a competing vaccine. I understand onset to commonly take some time. For me, I put it at about a 8 months between starting to feel a bit off in ways I now recognise was high blood sugar, and a diagnosis based on obvious Continue reading >>
Vaccines - Diabetes And The Environment
Most studies have not found vaccines to be associated with the development of type 1 diabetes or type 1-associated autoantibodies. For example: A meta-analysis of 11 studies found no associations between childhood type 1 diabetes and any routine vaccines ( Morgan et al. 2015). The HPV vaccine Gardasil did not increase the risk of type 1 diabetes, or any of the other 15 autoimmune conditions analyzed ( Chao et al. 2012). Another review also found that the HPV vaccine did not increase the risk of type 1 diabetes or other autoimmune conditions ( Grimaldi-Bensouda et al. 2017). Interestingly, the Pandemerix vaccine may have affected the efficacy of a diabetes-prevention intervention trial using the GAD-alum vaccine. It appears the GAD-alum vaccine was more effective in preserving beta cell function in people newly diagnosed with type 1 diabetes who did not have the Pandemerix vaccine ( Tavira et al. 2017). Some vaccines (e.g., BCG) may be able to accelerate the progression of type 1 diabetes, although most studies have not found associations between vaccines and type 1 diabetes. In case you were wondering, my children are fully vaccinated, and we also all get flu shots every year. Researchers are also working to develop a vaccine to prevent or treat type 1 diabetes, e.g., the GAD65 vaccine ( Ludvigsson 2017). To see or download the references cited on this page, see the collection Vaccines and diabetes/obesityin PubMed. Continue reading >>
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Type 1 Diabetes | Woman 2 Women
The HPV vaccine has been around for almost 10 years and more than 175 millions doseshave been distributed in 63 countries , with several studies confirming its safety and efficacy. In spite of that, the vaccine still remains a subject of controversy. Althoughrecommended by most scientific societies worldwide, some recent reports questioning its safety fuelled even more the debate, dividing both general public and medical community. In this articlewe will analyse the existing evidence regarding the HPV vaccine, with particular focus on its efficacyand safety.In order to organise the available information, the article will bedivided into the following sections: HPV (human papillomavirus) is a virus and is transmitted from person to person through skin-to-skin contact. HPV infection is extremely common, and most of the times it will be cleared by the immune system. Of the over 100 types of HPV, about 12 subtypes of the HPV (mostly subtypes 6 and 11) may cause genital warts (also known as condylomas). These so-called low-risk types can also cause a rare condition called recurrent respiratory papillomatosis, in which warts grow in the throat. Approximately 15 types of HPV (most commonly types 16 and 18) are related to cancer. While cervical cancer is the most common HPV-related cancer, this virus can also cause other cancers: vulvar, vaginal, anal and oropharyngeal (mouth and throat),as well as penile cancer in men. You can read more detailed information onHPV here . 2. Why a vaccine? The burden of HPV-related diseases These figures will give you and idea of the magnitude of the problems caused by HPV: -Worldwide, over 500,000 new cervical cancer cases are diagnosed annually. Cervical cancer ranks as the 4th cause of female cancer in the world and is the 2nd most common fem Continue reading >>
Autoimmune Disorders And Quadrivalent Human Papillomavirus Vaccination Of Youngfemale Subjects.
1. J Intern Med. 2014 Apr;275(4):398-408. doi: 10.1111/joim.12155. Epub 2013 Nov 22. Autoimmune disorders and quadrivalent human papillomavirus vaccination of youngfemale subjects. Grimaldi-Bensouda L(1), Guillemot D, Godeau B, Bnichou J, Lebrun-Frenay C,Papeix C, Labauge P, Berquin P, Penfornis A, Benhamou PY, Nicolino M, Simon A,Viallard JF, Costedoat-Chalumeau N, Courcoux MF, Pondarr C, Hilliquin P,Chatelus E, Foltz V, Guillaume S, Rossignol M, Abenhaim L; PGRx-AID Study Group. Collaborators: Abdelmoumni A, Hilliquin P, Requeda E, Adoue D, Brassat D,Aladjidi N, Clet J, Lemasson G, Perel Y, Vital A, Allain-Launay E, Bru M,Nicolino M, Thomas C, Altman JJ, Amsallem D, Aras N, Boukari L, Fain O, LetellierE, Lucidarme N, Mekinian A, Morin AS, Stirnemann J, Atlan C, Audry D, Augustin J,Bartolucci P, Chevalier X, Godeau B, Khellaf M, Limal N, Mahevas M, MliksetyanG, Michel M, Bayart S, Bonnet F, Decaux O, Bekherraz A, Brihaye B, Daugas E,Hayem G, Meyer O, Papo T, Pasqualoni E, Sacre K, Travert F, Beltrand J, LefrereF, Simon A, Benhamou PY, Benveniste O, Bolgert F, Costedoat-Chalumeau N, De PazR, Demeret S, Fautrel B, Jacqueminet S, Louapre C, Morel N, Papeix C, Rigabert J,Berger C, Berquin P, Le Moing AG, Besson G, Boutte C, Casez O, Bonnotte B, Audia S, Bossu-Estour C, Bourgarit A, Dupuy A, Keshmandt H, Brac A, Perrin A, Pondarr C, Villar-Fimbel S, Bruckert I, Cosson A, Magy-Bertrand N, Tisserand G, Camu W,Carlander B, Morales RJ, Cances C, Pasquet M, Charif M, Chatelus E, Sibilia J,Chevrant-Breton J, Courcoux MF, Leverger G, Machet L, Cuisset JM, Darsy P, Favre S, Giraud P, DeSeze J, Dinulescu M, Dupuis C, Durand JM, Farad S, Lecomte P,Pierre P, Fouyssac F, Gaudin P, Gellen-Dautremer J, Jarrin I, Richette P, Gras P,Moreau T, Giraud E, Hacini M, Mayer A, Guillaumat C, Gui Continue reading >>
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Vaccine Against Type 1 Diabetes 'shows Promise'
News of a successful trial of a vaccine for type 1 diabetes has been covered by BBC News, who reported that, “It may be possible to reverse type 1 diabetes by training a patient’s own immune system to stop attacking their body.” Type 1 diabetes is a condition where the body’s immune system destroys the insulin-producing beta cells of the pancreas. This means people with the condition require lifelong insulin treatment. It’s possible to block the effects of the immune system by using immunosuppressants, but this would make people more vulnerable to infections. An ideal type 1 diabetes treatment would block the immune cells attacking the pancreas while leaving the rest of the immune system untouched. New research suggests that this could be possible. A trial of a new vaccine compared its effects against placebo in just 80 people. The vaccine improved the function of the insulin-producing beta cells of the pancreas, but its effects seemed temporary as beta cell functioning declined soon after the regular vaccine injections were stopped. This suggests that regular vaccine injections might be required for it to work long-term, but this was not tested directly. There are thought to be many different substances that are recognised by, and possibly trigger, immune cells to attack the beta cells of the pancreas. This vaccine is quite specific in preventing just one such pathway. This means the vaccine may lead to an improvement in symptoms, but not a complete cure for the condition. Nonetheless, these are positive results and are likely to spur on larger and longer term studies. If all goes well, it could provide the basis for a new treatment approach for type 1 diabetes. Where did the story come from? The study was carried out by researchers from Europe, the US and Au Continue reading >>
Tallskinnykiwi: Hpv Vaccination And The Coercion Of Our 13 Year Old Diabetic Daughter
HPV vaccination and the coercion of our 13 year old diabetic daughter We are a bit shaken up over the HPV Vaccination, sometimes called the HPV Jab. It supposedly immunises young women against sexually transmitted disease that can lead to genital warts and cervical cancer but is not yet proven. However, for a number of reasons, my wife and I "opted out" by checking the 'No' box on the consent form, and our 13 year old daughter also decided NOT to get the jab. We figured with both parents and daughter against the idea, the jabbing would pass us by. But then she went to school and some anonymous doctor jabbed her anyway. We have no overt moral or spiritual issue with the immunization itself and, along with the FRC , we don't believe that the HPV immunisation necessarily leads to promiscuity. We do, however, have a problem with mandatory or coerced vaccination against the will of the child or the parents. But we were told we could "opt out" so we didn't give it much thought. On the day, our 13 year old daughter, who by the way has Type-1 Diabetes, was taken aside from the other girls and told by the doctor that she was the only girl in her year who had handed in a consent form with a cross in the 'No' box. As they started to talk, and without being asked if she wanted it, the doctor jabbed her. We have serious issues with this relatively untested and unproven drug Cervarix. Finding answers to basic questions like "How will it affect our Type-1 diabetic pre-adolescent daughter?" has proven impossible for us and I can only assume, unless the one of the 158 pre-adolescent [10-14 year] test candidates had Type-1 diabetes, that our daughter is now the gullible guinea pig who will test this product for the much larger international market. On the internet we call that "beta tes Continue reading >>
The Root Cause Of Type 1 Diabetes Could Be A Common Childhood Viral Infection
A young child becomes very thirsty very often and seems tired all the time. A visit to the pediatrician determines she has type 1 diabetes. The onset of type 1 diabetes may seem sudden, and it can be, but the disease may actually have been triggered by common childhood viruses years earlier. Type 1 diabetes—also called diabetes mellitus—was previously called juvenile-onset diabetes because most people affected with this disease are diagnosed as children and young adults. It isn't the most common form of diabetes and only 5% of people with diabetes have type 1. That doesn't make it any less serious—in fact, it can be a life-threatening disease. When we eat something, our body converts carbohydrates and starches in the food into sugar (glucose), which is then processed by our bodies to either be used or stored for later. People with type 1 diabetes have trouble keeping their blood sugar level even: It spikes when they eat something and goes very low if they don't. That's because their pancreas doesn't make insulin, the hormone that in a healthy human moves glucose from the blood into cells where it can be used for energy, keeping it from spiking after eating. Type 1 diabetics must constantly monitor their blood sugar and take insulin to keep their levels within a normal range to keep this process running. Type 1 diabetes is an autoimmune disease, a disease where the body forms antibodies to itself and attacks parts of its own body. In this case, antibodies are formed to the insulin-producing beta cells in the pancreas and destroys them. Experts believe type 1 diabetes may be caused by a genetic risk factors and environmental factors, including viruses. A viral link to type 1 diabetes is one of the findings in a new study led by Hanna Honkanen and Heikki Hyöty in th Continue reading >>