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How Long Does Novolog Take To Work

High Blood Sugar After Exercise?

High Blood Sugar After Exercise?

back to Overview Markus, one of our great German-language authors, wrote about struggling with high blood sugar after exercise. I know it's a common problem, and one I've struggled with personally, so I want to make sure you get to see it, too. From Markus Berndt: It’s one of the first recommendations you get after being diagnosed with diabetes. “Get active, do more exercise, it’s good for you!” And since we’ve been a child we’ve heard that exercise is healthy. If we do it consistently we’re rewarded, literally, with an awesome beach body. Adding exercise into our day is also good for our diabetes. We’re taught that exercise lowers blood sugar, right? But can the opposite also be true? Can you have high blood sugar after exercise? Up close We now know that physical activity usually lowers blood sugar because it reduces how much insulin is needed to move sugar into the cells. While, in the past, most experts advised frequent training intervals at moderate intensity, but recent studies have shown that even short, intense workouts are very effective. For example, a 15-minute intense weight training lowered blood sugar even more than what’s seen in some endurance training. So activity lowers blood sugar – but not always! Personally, I experienced this very early on and was extremely irritated! I just learned that exercise lowers blood sugar, but an intense 45-minute run consistently resulted in higher blood sugars than when I started! What in the world? At first, I was confused and felt like I didn’t understand the world anymore. Then it was more of a “would you look at this?” kind of thing. And finally, I was determined to figure out what was happening. I knew there had to be an explanation. Why does exercise sometimes raise blood sugar? Exercise Continue reading >>

Understanding R, N, And Premixed Insulins

Understanding R, N, And Premixed Insulins

Share: Sometimes due to choice, cost, insurance coverage you may find yourself on N, R, or pre-mixed insulin. The following is some information to understand what the types are, how they are taken, and who might be taking them. What is R insulin and when should I take it? Regular or R insulin is clear in color, considered short acting, and is available in names including: Humulin R, Novolin R, ReliOn R. This insulin starts working in 30 minutes and lasts for about 5-8 hours. Regular insulin is taken 30 minutes before meals. It helps to provide coverage for your meals. If you use in combination with N insulin, you would take it before breakfast and dinner. If skipping a meal, you would skip your R insulin. How much is R insulin? R insulin is considerably cheaper than rapid acting analogs such as Humalog or Novolog. Check with your pharmacy for exact pricing. What is N insulin and when should I take it? NPH (N) is a cloudy colored, intermediate acting insulin, and is available as Humulin N, Novolin N, ReliOn N. It starts working in about 1-3 hours, and can last for approximately 10-18 hours. N insulin helps to cover in between your meals and the N you take at breakfast will still be working at lunch to cover your meal. It is essential that you have lunch every day, about 4-5 hours after you inject your N at breakfast. If you do not have lunch, you will be at risk for going too low. The N you take at bed will work during the night to help regular your morning glucose levels. You should have a small bed time snack. NPH or N insulin would be taken with breakfast and before bed for better fasting glucose levels, however instead of giving it at bed, it may be given before dinner also. How much is N insulin? N insulin is a cheaper alternative to longer acting insulins. Check wi Continue reading >>

When Do Humalog And Novolog Insulins Really Work?

When Do Humalog And Novolog Insulins Really Work?

A problem associated with the use of rapid insulins is that situations occur that cause people to perceive them as faster than they really are. For example, a person may feel perfectly normal at 70 mg/dl (3.9 mmol), take a bolus of rapid insulin for a meal, and a few minutes later begin to shake, sweat and have trouble thinking. Though the timing of the symptoms gives the impression that rapid insulin is responsible and acts very quickly, the symptoms are unlikely to be caused by the rapid insulin just given. More likely, another insulin given earlier is causing the blood sugar to drop. A drop of only a few mg/dl causes a person to go from feeling normal to feeling low. Because the meal bolus was just given, it often receives the blame for a low caused by an insulin that was given earlier. The kinetics of an insulin are when that insulin can be measured in the bloodstream, whereas an insulin's dynamics are when it actually affects the blood sugar. After an injection, peak levels of Humalog and Novolog insulins are seen in the bloodstream about 45 minutes later, as shown by the dashed kinetic line to the right. However, the effect on your blood sugar is not nearly this quick. The solid dynamic line to the right shows when these insulins are actually lowering the blood sugar. The maximum effect on lowering the glucose level is not seen until 2 hours after an injection and continues for over 4 hours. Another situation often seems to confirm for many the false impression that a rapid insulin is really rapid. This occurs when a carb or correction bolus is given and a low blood sugar begins only an hour or two later. Here, the rapid insulin is likely at fault, but again the low blood sugar is not caused by any rapid action. Rather, the quick drop in blood sugar seen in the bl Continue reading >>

Novo Nordisk Receives Fda Approval For Fiasp®, A New Fast-acting Mealtime Insulin

Novo Nordisk Receives Fda Approval For Fiasp®, A New Fast-acting Mealtime Insulin

® (insulin aspart injection) 100 Units/mL, a fast-acting mealtime insulin indicated to improve glycemic control in adults with type 1 and type 2 diabetes.1 Fiasp® can be dosed at the beginning of a meal or within 20 minutes after starting a meal. Fiasp® is a new formulation of NovoLog®, in which the addition of niacinamide (vitamin B3) helps to increase the speed of the initial insulin absorption, resulting in an onset of appearance in the blood in approximately 2.5 minutes.2 Fiasp® will be available in a pre-filled delivery device FlexTouch® pen and a 10 mL vial.1 Many adults with type 1 and type 2 diabetes struggle with blood sugar control after meals. The result of this has led to many people with diabetes not achieving their target A1C. "With Fiasp®, we've built on the insulin aspart molecule to create a new treatment option to help patients meet their post-meal blood sugar target," said Bruce Bode, MD FACE, President of Atlanta Diabetes Associates and Associate Professor at Emory University School of Medicine. "The intention of rapid acting insulin therapy is to mimic, as much as possible, the natural physiological insulin response that occurs after meals, a process that is important for optimal A1C management." Fiasp® will launch at the same list price as NovoLog® and will be offered with a Savings Card program for eligible patients with commercial insurance to reduce co-pays. Fiasp® will also be available to eligible patients through the Novo Nordisk Patient Assistance Program. Patients and caregivers can obtain more information and access to the Novo Nordisk Patient Assistance Program by calling toll free at 866-310-7549. The approval of Fiasp® is based on results from the onset phase 3a clinical development program. The clinical trials enrolled more Continue reading >>

Know About Novolog Insulin Peak Time, Onset And Duration Of Action

Know About Novolog Insulin Peak Time, Onset And Duration Of Action

What is Novolog? Novolog is a fast acting insulin that is used to treat patients with diabetes mellitus. It can be prescribed to adults with type 2 diabetes, and adults and children above the age of 2 with type 1 diabetes. Novolog is also known as insulin aspart. Insulin aspart is a man made insulin that mimics the way the natural hormone works, which is to help glucose enter the body’s cells to be used for fuel. When you inject this insulin, it starts to work quickly to reduce your blood sugar levels. After using insulin aspart, it is advised that you eat within 5 to 10 minutes tp prevent low blood sugar. This medication is usually prescribed together with intermediate or long acting insulin. Novolog insulin peak time, onset and duration of action Insulin types such as novolog are usually classified according to the time period they take to control blood sugar levels. To understand how this medication works in the body, it is important you know the meaning of onset, peak, and duration of the medication. The onset refers to how fast it takes before the insulin begins to reduce blood sugar levels in people with diabetes. On the other hand, peak refers to the time when insulin is working the best in the body to reduce blood sugar levels. The duration refers to how long the insulin keeps working in your body. The drug peak time is generally between one to four hours, while novolog onset is between 10 to 20 minutes. How to take it Novolog can be injected subcutaneously using an injection pen or a syringe. Your healthcare provider will show you the best part of your body to inject this medication. Usually, it is injected into the fat tissue of the stomach, thigh, upper arm or buttocks. You should not inject this medication on the same spot twice. Instead, change the inject Continue reading >>

Novolog

Novolog

Novolog is a prescription medication used to treat type 1 and type 2 diabetes. Novolog is a fast-acting form of insulin. It is usually given with a long-acting insulin to provide a steady amount of insulin to control blood glucose (sugar) levels. This medication comes in an injectable form available in vials and prefilled pens. Novolog should be injected just under the skin 5 to 10 minutes before meals. It may also be injected directly into a vein (IV) by a healthcare provider or by an insulin pump. Common side effects of Novolog include low blood sugar, reaction at the injection site, and weight gain. Novolog is a prescription medication used to control high blood sugar in adults and children with type 1 or type 2 diabetes. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Serious side effects may occur. See "Novolog Precautions" section. Common side effects of Novolog include weight gain, reaction at the injection site, and low blood sugar. Low blood sugar (hypoglycemia) is the most common side effect seen with Novolog use. Symptoms of low blood sugar may include: sweating dizziness or lightheadedness shakiness hunger fast heart beat tingling of lips and tongue trouble concentrating or confusion blurred vision slurred speech anxiety, irritability or mood changes headache Severe low blood sugar can cause unconsciousness (passing out), seizures, and death. Know your symptoms of low blood sugar. Follow your healthcare provider’s instructions for treating low blood sugar. Talk to your healthcare provider if low blood sugar is a problem for you. Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you tak Continue reading >>

Insulin Aspart

Insulin Aspart

Insulin aspart is a fast-acting insulin analog marketed by Novo Nordisk as NovoLog/NovoRapid. It is a manufactured form of human insulin; where a single amino acid has been exchanged. This change helps the fast-acting insulin analog be absorbed quickly into the bloodstream. As a result, it starts working in minutes, which allows one to take insulin and eat right away. Fast-acting insulin analogs are considered to act similarly to the way insulin is released in people without diabetes mellitus. Novolog allows for a flexible dosing schedule, which allows patients to adjust their insulin according to any changes in their eating habits.[1] The safety and efficacy of insulin aspart (NovoLog/NovoRapid) in real-life clinical practice was evaluated in the A1chieve study. It was created through recombinant DNA technology so that the amino acid, B28, which is normally proline, is substituted with an aspartic acid residue. This analog has increased charge repulsion, which prevents the formation of hexamers, to create a faster-acting insulin. The sequence was inserted into the yeast genome, and the yeast expressed the insulin analog, which was then harvested from a bioreactor. According to JDRF, insulin aspart was approved for marketing in the United States by the Food and Drug Administration in June 2000.[citation needed] Chemical properties[edit] The components of insulin aspart are as follows: Metal ion – zinc (19.6 μg/mL) Buffer – disodium hydrogen phosphate dihydrate (1.25 mg/mL) Preservatives – m-cresol (1.72 mg/mL) and phenol (1.50 mg/mL) Isotonicity agents – glycerin (16 mg/mL) and sodium chloride (0.58 mg/mL). The pH of insulin aspart is 7.2–7.6.[2] Action time[edit] The onset of action is approximately 15 minutes, the peak action is reached in 45–90 minutes, Continue reading >>

Novolog, Novolog Flexpen, Novolog Penfill

Novolog, Novolog Flexpen, Novolog Penfill

What is NovoLog? NovoLog (insulin aspart)is a fast-acting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. NovoLog is used to improve blood sugar control in adults and children with diabetes mellitus. This medicine is sometimes used together with a long-acting or intermediate-acting insulin. NovoLog is used to treat type 2 diabetes in adults. NovoLog is also used to treat type 1 diabetes in adults and children who are at least 2 years old. Important information NovoLog is a fast-acting insulin that begins to work very quickly. After using it, you should eat a meal within 5 to 10 minutes. Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another. You should not use NovoLog if you are having an episode of hypoglycemia (low blood sugar). Before taking this medicine You should not use NovoLog if you are allergic to insulin aspart, or if you are having an episode of hypoglycemia (low blood sugar). NovoLog is not approved for use by anyone younger than 2 years old. This medicine should not be used to treat type 2 diabetes in a child of any age. To make sure NovoLog is safe for you, tell your doctor if you have: liver or kidney disease; or low levels of potassium in your blood (hypokalemia). Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems. Follow your doctor's instructions about using insulin if you are pregn Continue reading >>

Insulin For Gestational Diabetes

Insulin For Gestational Diabetes

Examples Rapid-acting Generic Name Brand Name insulin aspart NovoLog insulin lispro Humalog Short-acting Intermediate-acting Long-acting Mixtures Generic Name Brand Name 50% lispro protamine and 50% lispro Humalog Mix 50/50 50% NPH and 50% regular Humulin 50/50 70% aspart protamine and 30% aspart NovoLog Mix 70/30 70% NPH and 30% regular Humulin 70/30, Novolin 70/30 75% lispro protamine and 25% lispro Humalog Mix 75/25 Insulin normally is made by the pancreas, a gland behind the stomach. The medicine form of insulin helps the body use glucose. Insulin cannot be taken as a pill, because stomach acid destroys insulin before it can enter the blood. Insulin is categorized according to how fast it starts to work and how long it continues to work. The types of insulin available include rapid-, short-, intermediate-, and long-acting insulin. See types of insulin for more information. Packaging Insulin is packaged in small glass bottles that are sealed with rubber lids. One bottle of U-100 insulin holds 1,000 units, which is many doses of insulin. It is also packaged in small cartridges used in pen-shaped devices (insulin pens) attached to disposable needles. Insulin bottles and cartridges are labeled with important information you should read, such as the expiration date. How insulin is taken Insulin usually is given as a shot under the skin. It can also be given through an insulin pump or a jet injector, a device that sprays the medicine into the skin. Some insulins can be given in a vein, but this is only done in a hospital. How It Works Insulin reduces blood sugar levels by helping sugar (glucose) enter the cells to be used for energy. Sometimes women who have gestational diabetes need to take two types of insulin, usually a rapid- or short-acting and an intermediate-acting Continue reading >>

Novocare | Savings Card For Novolog (insulin Aspart Injection) 100 Units/ml

Novocare | Savings Card For Novolog (insulin Aspart Injection) 100 Units/ml

Some error has occurred. Please try again. User already exists. We're sorry, your account is currently unavailable. We're currently working to fix the issue. Please check back soon. {{registerModel.webserviceError}} Do not share your NovoLog FlexPen, NovoLog FlexTouch, PenFill cartridge or PenFill cartridge compatible insulin delivery device with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients. Read the Instructions for Use and take exactly as directed. NovoLog is fast-acting. Eat a meal within 5 to 10 minutes after taking it. Know the type and strength of your insulin. Do not change your insulin type unless your health care provider tells you to. Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them. Do not reuse or share your needles with other people. You may give other people a serious infection, or get a serious infection from them. What is NovoLog(insulin aspart injection) 100 U/mL? NovoLogis a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus. Do not share your NovoLog FlexPen, NovoLog FlexTouch, PenFill cartridge or PenFill cartridge compatible insulin delivery device with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them. your blood sugar is too low (hypoglycemia) or you are allergic to any of its ingredients. Before taking NovoLog, tell your health care provider about all your medical conditions including, if you are: pregnant, plan to become pregnant, or are breastfeeding. taking Continue reading >>

Types Of Insulin

Types Of Insulin

A A A Topic Overview Insulin is used to treat people who have diabetes. Each type of insulin acts over a specific amount of time. The amount of time can be affected by exercise, diet, illness, some medicines, stress, the dose, and where the insulin has been injected. Insulin strength is usually U-100, or 100 units of insulin in one milliliter of fluid. Short-acting (regular) insulin is also available in U-500, or 500 units of insulin in one milliliter of fluid. This is five times more concentrated than U-100 regular insulin. Insulin is made by different companies. Make sure you use the same type of insulin consistently. Types of insulin Type Examples Appearance When it starts to work (onset) The time of greatest effect (peak) How long it lasts (duration) Rapid-acting Apidra (insulin glulisine) Clear 5–15 minutes 30–60 minutes 3–5 hours Humalog (insulin lispro) Clear 5–15 minutes 30–90 minutes 3–5 hours NovoLog (insulin aspart) Clear 5–15 minutes 40–50 minutes 3–5 hours Short-acting Humulin R, Novolin R (insulin regular) Clear 30 minutes 1½–2 hours 6–8 hours Intermediate-acting Humulin N, Novolin N (insulin NPH) Cloudy 1–4 hours 4–12 hours 14–24 hours Long-acting Lantus (insulin glargine) Clear 1–2 hours Minimal peak Up to 24 hours Levemir (insulin detemir) Clear 2 hours Minimal peak Up to 24 hours Rapid-acting insulins work over a narrow, more predictable range of time. Because they work quickly, they are used most often at the start of a meal. Rapid-acting insulin acts most like insulin that is produced by the human pancreas. It quickly drops the blood sugar level and works for a short time. If a rapid-acting insulin is used instead of a short-acting insulin at the start of dinner, it may prevent severe drops in blood sugar level in the m Continue reading >>

Novolog Penfill Solution For Injection Drug Information, Side Effects, Faqs

Novolog Penfill Solution For Injection Drug Information, Side Effects, Faqs

-an unusual or allergic reaction to insulin, metacresol, other medicines, foods, dyes, or preservatives This medicine is for injection under the skin. Use exactly as directed. It is important to follow the directions given to you by your health care professional or doctor. If you are using Novolog, you should start your meal within 5 to 10 minutes after injection. If you are using Fiasp, you should start your meal at the time of injection or within 20 minutes after injection. Have food ready before injection. Do not delay eating. You will be taught how to use this medicine and how to adjust doses for activities and illness. Do not use more insulin than prescribed. Do not use more or less often than prescribed. Always check the appearance of your insulin before using it. This medicine should be clear and colorless like water. Do not use if it is cloudy, thickened, colored, or has solid particles in it. If you use a pen, be sure to take off the outer needle cover before using the dose. It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one. Talk to your pediatrician regarding the use of this medicine in children. While Novolog may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply. Fiasp is not approved for use in children. It is important not to miss a dose. Your health care professional or doctor should discuss a plan for missed doses with you. If you do miss a dose, follow their plan. Do not take double doses. Visit your health care professional or doctor for regular checks on your progress. A test called the HbA1C (A1C) will be monitored. This is a simple bloo Continue reading >>

Insulin Dosing Made Simple

Insulin Dosing Made Simple

I have found, in my years of practicing correctional medicine, that few practitioners who come to corrections are comfortable with insulin dosing. In my experience, this is especially true for physician assistants and nurse practitioners, but many physicians have problems, too. Insulin dosing can be complicated and tricky at times, but for most patients, 10 simple rules will get you to where you need to be. We first need to cover some groundwork and some terms. Insulin terminology can be confusing. First, it is very important to remember that this discussion applies to type 1 diabetics only. Type 2 diabetics sometimes use insulin, but that’s a “whole ‘nother ballgame.” There are two types of insulin used for two very different purposes when treating type 1 diabetics. The first is basal insulin, which is used to replace the insulin that the normal pancreas releases constantly—whether we eat or not. Long-acting insulin is used to provide coverage for the basal metabolic needs of type 1 diabetics. Examples are insulin glargine (Lantus) and insulin detemir (Levemir). The most commonly used long-acting insulin is Lantus, so I am going to use that name in this article. (I have no financial ties to the maker of Lantus—I use that name because it is the name most commonly used by patients). The second type of insulin that type 1 diabetics need is short-acting insulin, which is given to cover the carbohydrates in the food they eat. Short-acting insulins are given just before a meal or snack and, ideally, the dose should vary depending on how many carbohydrates are in the food. Examples of short acting insulins are insulin regular, insulin aspart (Novolog) and insulin lispro (Humalog). Again, I will use the term Humalog in this article because it is the term most often Continue reading >>

High-alert Medications - Novolog (insulin Aspart)

High-alert Medications - Novolog (insulin Aspart)

Extra care is needed because NovoLog is a high-alert medicine. High-alert medicines have been proven to be safe and effective. But these medicines can cause serious injury if a mistake happens while taking them. This means that it is very important for you to know about this medicine and take it exactly as directed. Top 10 List of Safety Tips for NovoLog When taking your medicine 1. Know your insulin. NovoLog is a rapid-acting form of insulin that should be injected below the skin 5 to 10 minutes before meals. Have food ready before injection. After injecting the insulin, do not skip a meal or delay eating. 2. Prepare your insulin. An intermediate- or long-acting insulin is often prescribed with NovoLog. NovoLog can be mixed with insulin NPH (intermediate-acting insulin), but always draw NovoLog into the syringe first. Never mix NovoLog with Lantus. Do not mix NovoLog with other insulins if using an insulin pen or external pump. Do not vigorously shake insulin before use. 3. Don't reuse or recycle. Dispose of used syringes/needles, pens, and lancets in a sealable hard plastic or metal container (e.g., empty detergent bottle, special sharps container from your pharmacy). When the container is full, seal the lid before placing it in the trash. Do not reuse or recycle syringes/needles or lancets. 4. Don't share. Even if you change the needle, sharing an insulin pen or syringe may spread diseases carried in the blood, including hepatitis and HIV. To avoid serious side effects 5. Avoid mix-ups. If you use more than one type of insulin, make each vial or pen look different by putting a rubber band around one type of insulin. 6. Check your medicine. NovoLog can be confused with Humalog (another rapid-acting insulin). When you pick up your insulin at the pharmacy, be sure it's Continue reading >>

Novolog

Novolog

Last reviewed on RxList 11/13/2017 NovoLog (insulin aspart [rDNA origin] injection) is a form of insulin, a hormone that is produced in the body, used to treat type 1 (insulin-dependent) diabetes in adults and children who are at least 2 years old. NovoLog is usually given together with another long-acting insulin. The most common side effect of NovoLog is low blood sugar (hypoglycemia). Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, trouble concentrating, confusion, or seizure (convulsions). Other common side effects of NovoLog include: injection site reactions (e.g., pain, redness, irritation). Tell your doctor right away if you have any serious side effects of NovoLog including: signs of low potassium level in the blood (such as muscle cramps, weakness, or irregular heartbeat). The dosage of NovoLog is individualized. The total daily insulin requirement may vary and is usually between 0.5 to 1.0 units/kg/day. NovoLog may interact with albuterol, clonidine, reserpine, guanethidine, or beta-blockers. There are many other medicines that can increase or decrease the effects of insulin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Tell your doctor if you are pregnant before using NovoLog. Tell your doctor if you become pregnant. Your doctor may switch the type of insulin you use during pregnancy. This medication does not pass into breast milk. Your insulin needs may change while breastfeeding. Consult your doctor before breastfeeding. Our NovoLog (insulin aspart [rDNA origin] injection) Side Effects Drug Center provides a comprehens Continue reading >>

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