
Type 1 Diabetes In Children
The most common type of diabetes in children is type 1 diabetes. In fact, according to the American Diabetes Association, type 1 diabetes is one of the most common chronic diseases in children. Type 1 diabetes accounts for 5 percent of all diagnosed cases of diabetes in the U.S. What is type 1 diabetes? Type 1 diabetes may also be known by a variety of other names, including: Insulin-dependent diabetes mellitus (IDDM) Juvenile diabetes Brittle diabetes Sugar diabetes There are two forms of type 1 diabetes: Idiopathic type 1. This refers to rare forms of the disease with no known cause. Immune-mediated diabetes. An autoimmune disorder in which the body's immune system destroys, or attempts to destroy, the cells in the pancreas that produce insulin. Immune-mediated diabetes is the most common form of type 1 diabetes and is generally referred to as type 1 diabetes. What causes type 1 diabetes? The cause of type 1 diabetes is unknown. However, it is believed that people inherit a tendency to develop diabetes, and that some outside trigger may be involved. Type 1 diabetes is the result of the body's failure to produce insulin, the hormone that allows glucose to enter the cells of the body to provide fuel. This is the result of an autoimmune process in which the body's immune system attacks and destroys the insulin producing cells of the pancreas. When glucose cannot enter the cells, it builds up in the blood, depriving the cells of nutrition. People with type 1 diabetes must take daily insulin injections and regularly monitor their blood sugar levels. What are the symptoms of type 1 diabetes? Type 1 diabetes often appears suddenly. In children, type 1 diabetes symptoms may resemble flu symptoms. The following are the most common symptoms for type 1 diabetes. However, each ch Continue reading >>

Diabetes Mystery: Why Are Type 1 Cases Surging?
When public health officials fret about the soaring incidence of diabetes in the U.S. and worldwide, they are generally referring to type 2 diabetes. About 90 percent of the nearly 350 million people around the world who have diabetes suffer from the type 2 form of the illness, which mostly starts causing problems in the 40s and 50s and is tied to the stress that extra pounds place on the body’s ability to regulate blood glucose. About 25 million people in the U.S. have type 2 diabetes, and another million have type 1 diabetes, which typically strikes in childhood and can be controlled only with daily doses of insulin. For reasons that are completely mysterious, however, the incidence of type 1 diabetes has been increasing throughout the globe at rates that range from 3 to 5 percent a year. Although the second trend is less well publicized, it is still deeply troubling, because this form of the illness has the potential to disable or kill people so much earlier in their lives. No one knows exactly why type 1 diabetes is rising. Solving that mystery—and, if possible, reducing or reversing the trend—has become an urgent problem for public health researchers everywhere. So far they feel they have only one solid clue. “Increases such as the ones that have been reported cannot be explained by a change in genes in such a short period,” says Giuseppina Imperatore, who leads a team of epidemiologists in the Division of Diabetes Translation at the U.S. Centers for Disease Control and Prevention. “So environmental factors are probably major players in this increase.” A Challenge of Counting Type 1 and type 2 diabetes share the same underlying defect—an inability to deploy insulin in a manner that keeps blood sugar from rising too high—but they arise out of almos Continue reading >>

Type 1 Diabetes
Type 1 diabetes is much less common than type 2 diabetes and typically affects younger individuals. Type 1 diabetes usually begins before age 40, although there have been people diagnosed at an older age. In the United States, the peak age at diagnosis is around 14. Type 1 diabetes is associated with deficiency (or lack) of insulin. It is not known why, but the pancreatic islet cells quit producing insulin in the quantities needed to maintain a normal blood glucose level. Without sufficient insulin, the blood glucose rises to levels which can cause some of the common symptoms of hyperglycemia. These individuals seek medical help when these symptoms arise, but they often will experience weight loss developing over several days associated with the onset of their diabetes. The onset of these first symptoms may be fairly abrupt or more gradual. To learn more about type 1 diabetes basics, see our type 1 diabetes slideshow. It has been estimated that the yearly incidence of type 1 diabetes developing is 3.7 to 20 per 100,000. More than 700,000 Americans have this type of diabetes. This is about 10% of all Americans diagnosed with diabetes; the other 90% have type 2 diabetes. What You Need to Know about Type 1 Diabetes Type 1 Diabetes Causes Type 1 diabetes usually develops due to an autoimmune disorder. This is when the body's immune system behaves inappropriately and starts seeing one of its own tissues as foreign. In the case of type 1 diabetes, the islet cells of the pancreas that produce insulin are seen as the "enemy" by mistake. The body then creates antibodies to fight the "foreign" tissue and destroys the islet cells' ability to produce insulin. The lack of sufficient insulin thereby results in diabetes. It is unknown why this autoimmune diabetes develops. Most often Continue reading >>

Type 1 Diabetes
Type 1 diabetes can occur at any age. It is most often diagnosed in children, adolescents, or young adults. Insulin is a hormone produced in the pancreas by special cells, called beta cells. The pancreas is below and behind the stomach. Insulin is needed to move blood sugar (glucose) into cells. Inside the cells, glucose is stored and later used for energy. With type 1 diabetes, beta cells produce little or no insulin. Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. This buildup of glucose in the blood is called hyperglycemia. The body is unable to use the glucose for energy. This leads to the symptoms of type 1 diabetes. The exact cause of type 1 diabetes is unknown. Most likely, it is an autoimmune disorder. This is a condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue. With type 1 diabetes, an infection or another trigger causes the body to mistakenly attack the cells in the pancreas that make insulin. The tendency to develop autoimmune diseases, including type 1 diabetes, can be passed down through families. Continue reading >>

What Is Type 1 Diabetes
Type 1 diabetes is caused by the immune system mistakenly turning on itself, destroying beta cells within the pancreas and removing the body's ability to produce insulin. Insulin allows the body to process sugar to create energy - without insulin, the body literally starves as it cannot process food. Treating Type 1 Diabetes The goal of type 1 diabetes management is to keep blood glucose levels as close to the normal range as possible. It sounds easy, but in reality, this is very difficult to achieve. To stay alive, people with type 1 diabetes must have a constant supply of insulin through injections or an insulin pump and they test their blood sugar by pricking their fingers at least four times a day. People with type 1 diabetes must be constantly prepared for potential hypoglycaemic (low blood sugar) and hyperglycaemic (high blood sugar) reactions, which can both be life threatening. Hypoglycaemia and Hyperglycaemia Hypoglycaemia (low blood sugar) is a common and dangerous condition for many people with type 1 diabetes. It can be caused by eating less than usual, more exercise than normal or too much insulin administered. Hyperglycaemia (high blood sugar) occurs when the body has too much food or glucose, or too little insulin. It can be caused by a clog in insulin pump tubing, missing an insulin dose, eating more than usual, stress or less exercise than normal. These low and high blood sugar level reactions show the constant balance that those with type 1 diabetes have to endure in their everyday life. Type 1 Diabetes Statistics Type 1 diabetes is one of the most common chronic diseases in children, it occurs more frequently than cancer, cystic fibrosis, multiple sclerosis and muscular dystrophy Approximately 2400 Australians are diagnosed with type 1 diabetes every Continue reading >>

Diabetes In Children And Teens: Signs And Symptoms
With more than a third of diabetes cases in the United States occurring in people over the age of 65, diabetes is often referred to as an age-related condition. But around 208,000 children and adolescents are estimated to have diabetes, and this number is increasing. Type 1 diabetes is the most common form of the condition among children and adolescents. A 2009 report from the Centers for Disease Control and Prevention (CDC) revealed that type 1 diabetes prevalence stands at 1.93 in every 1,000 children and adolescents, while type 2 diabetes affects 0.24 in every 1,000. In 2014, Medical News Today reported that, based on a study published in JAMA, rates of both type 1 and type 2 diabetes have increased significantly among American children and teenagers. The study found that incidence of type 1 diabetes in children aged up to 9 years increased by 21 percent between 2001 and 2009, while incidence of type 2 diabetes among youths aged 10-19 years rose by 30.5 percent. The researchers note: "The increases in prevalence reported herein are important because such youth with diabetes will enter adulthood with several years of disease duration, difficulty in treatment, an increased risk of early complications and increased frequency of diabetes during reproductive years, which may further increase diabetes in the next generation." Contents of this article: Here are some key points about diabetes in children. More detail and supporting information is in the main article. Type 1 and 2 diabetes are both increasing in the youth of America Often, the symptoms of type 1 diabetes in children develop over just a few weeks If type 1 diabetes is not spotted, the child can develop diabetic ketoacidosis (DKA) What is diabetes in children? Type 1 diabetes in children, previously called juve Continue reading >>

Type 1 Diabetes
Type 1 diabetes is the type of diabetes that typically develops in children and in young adults. In type 1 diabetes the body stops making insulin and the blood sugar (glucose) level goes very high. Treatment to control the blood glucose level is with insulin injections and a healthy diet. Other treatments aim to reduce the risk of complications. They include reducing blood pressure if it is high and advice to lead a healthy lifestyle. What is type 1 diabetes? What is type 1 diabetes? Play VideoPlayMute0:00/0:00Loaded: 0%Progress: 0%Stream TypeLIVE0:00Playback Rate1xChapters Chapters Descriptions descriptions off, selected Subtitles undefined settings, opens undefined settings dialog captions and subtitles off, selected Audio TrackFullscreen This is a modal window. Beginning of dialog window. Escape will cancel and close the window. TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal Dialog End of dialog window. Diabetes mellitus (just called diabetes from now on) occurs when the level of sugar (glucose) in the blood becomes higher than normal. There are two main types of diabetes. These are called type 1 diabetes and type 2 diabetes. Type 1 diabetes usually first develops in children or young adults. In the UK about 1 in 300 people develop type 1 diabetes at some stage. With type 1 diabet Continue reading >>

Type 1 Diabetes
Whether you have type 1 diabetes, are a caregiver or loved one of a person with type 1 diabetes, or just want to learn more, the following page provides an overview of type 1 diabetes. New to type 1 diabetes? Check out "Starting Point: Type 1 Diabetes Basics," which answers some of the basic questions about type 1 diabetes: what is type 1 diabetes, what are its symptoms, how is it treated, and many more! Want to learn a bit more? See our “Helpful Links” page below, which provides links to diaTribe articles focused on type 1 diabetes. These pages provide helpful tips for living with type 1 diabetes, our patient-perspective column by Adam Brown, drug and device overviews, information about diabetes complications, and some extra pages we hope you’ll find useful! Starting Point: Type 1 Diabetes Basics What is the risk of developing type 1 diabetes if it runs in my family? What is Type 1 Diabetes? Type 1 diabetes is disease in which the body can no longer produce insulin. Insulin is normally needed to convert sugar (also called glucose) and other food sources into energy for the body’s cells. It is believed that in people with type 1 diabetes, the body’s own immune system attacks and kills the beta cells in the pancreas that produce insulin. Without insulin, the body cannot control blood sugar, and people can suffer from dangerously high blood sugar levels (called hyperglycemia). To control their blood glucose levels, people with type 1 diabetes take insulin injections. Before the discovery of insulin, type 1 diabetes was a death sentence (and it still is for patients with poor access to insulin). Can Type 1 Diabetes Be Prevented? Unfortunately, the genetic and environmental triggers for the immune attack that causes type 1 diabetes are not well understood, althoug Continue reading >>

Type 1 Diabetes Mellitus
Practice Essentials Type 1 diabetes is a chronic illness characterized by the body’s inability to produce insulin due to the autoimmune destruction of the beta cells in the pancreas. Although onset frequently occurs in childhood, the disease can also develop in adults. [1] See Clinical Findings in Diabetes Mellitus, a Critical Images slideshow, to help identify various cutaneous, ophthalmologic, vascular, and neurologic manifestations of DM. Signs and symptoms The classic symptoms of type 1 diabetes are as follows: Other symptoms may include fatigue, nausea, and blurred vision. The onset of symptomatic disease may be sudden. It is not unusual for patients with type 1 diabetes to present with diabetic ketoacidosis (DKA). See Clinical Presentation for more detail. Diagnosis Diagnostic criteria by the American Diabetes Association (ADA) include the following [2] : Lab studies A fingerstick glucose test is appropriate for virtually all patients with diabetes. All fingerstick capillary glucose levels must be confirmed in serum or plasma to make the diagnosis. All other laboratory studies should be selected or omitted on the basis of the individual clinical situation. An international expert committee appointed by the ADA, the European Association for the Study of Diabetes, and the International Diabetes Association recommended the HbA1c assay for diagnosing type 1 diabetes only when the condition is suspected but the classic symptoms are absent. [3] Screening Screening for type 1 diabetes in asymptomatic low-risk individuals is not recommended. [2] However, in patients at high risk (eg, those who have first-degree relatives with type 1 diabetes), it may be appropriate to perform annual screening for anti-islet antibodies before the age of 10 years, along with 1 additional Continue reading >>
- Women in India with Gestational Diabetes Mellitus Strategy (WINGS): Methodology and development of model of care for gestational diabetes mellitus (WINGS 4)
- Postprandial Blood Glucose Is a Stronger Predictor of Cardiovascular Events Than Fasting Blood Glucose in Type 2 Diabetes Mellitus, Particularly in Women: Lessons from the San Luigi Gonzaga Diabetes Study
- Metabolic surgery for treating type 2 diabetes mellitus: Now supported by the world's leading diabetes organizations

Type 1 Diabetes
Type 1 diabetes is a disorder characterized by abnormally high blood sugar levels. In this form of diabetes, specialized cells in the pancreas called beta cells stop producing insulin. Insulin controls how much glucose (a type of sugar) is passed from the blood into cells for conversion to energy. Lack of insulin results in the inability to use glucose for energy or to control the amount of sugar in the blood. Type 1 diabetes can occur at any age; however, it usually develops by early adulthood, most often starting in adolescence. The first signs and symptoms of the disorder are caused by high blood sugar and may include frequent urination (polyuria), excessive thirst (polydipsia), fatigue, blurred vision, tingling or loss of feeling in the hands and feet, and weight loss. These symptoms may recur during the course of the disorder if blood sugar is not well controlled by insulin replacement therapy. Improper control can also cause blood sugar levels to become too low (hypoglycemia). This may occur when the body's needs change, such as during exercise or if eating is delayed. Hypoglycemia can cause headache, dizziness, hunger, shaking, sweating, weakness, and agitation. Uncontrolled type 1 diabetes can lead to a life-threatening complication called diabetic ketoacidosis. Without insulin, cells cannot take in glucose. A lack of glucose in cells prompts the liver to try to compensate by releasing more glucose into the blood, and blood sugar can become extremely high. The cells, unable to use the glucose in the blood for energy, respond by using fats instead. Breaking down fats to obtain energy produces waste products called ketones, which can build up to toxic levels in people with type 1 diabetes, resulting in diabetic ketoacidosis. Affected individuals may begin breathin Continue reading >>

Type 1 Diabetes
happens when your immune system destroys cells in your pancreas called beta cells. They’re the ones that make insulin. Some people get a condition called secondary diabetes. It’s similar to type 1, except the immune system doesn’t destroy your beta cells. They’re wiped out by something else, like a disease or an injury to your pancreas. Insulin is a hormone that helps move sugar, or glucose, into your body's tissues. Cells use it as fuel. Damage to beta cells from type 1 diabetes throws the process off. Glucose doesn’t move into your cells because insulin isn’t there to do it. Instead it builds up in your blood and your cells starve. This causes high blood sugar, which can lead to: Dehydration. When there’s extra sugar in your blood, you pee more. That’s your body’s way of getting rid of it. A large amount of water goes out with that urine, causing your body to dry out. Weight loss. The glucose that goes out when you pee takes calories with it. That’s why many people with high blood sugar lose weight. Dehydration also plays a part. Diabetic ketoacidosis (DKA). If your body can't get enough glucose for fuel, it breaks down fat cells instead. This creates chemicals called ketones. Your liver releases the sugar it stores to help out. But your body can’t use it without insulin, so it builds up in your blood, along with the acidic ketones. This combination of extra glucose, dehydration, and acid buildup is known as "ketoacidosis" and can be life-threatening if not treated right away. Damage to your body. Over time, high glucose levels in your blood can harm the nerves and small blood vessels in your eyes, kidneys, and heart. They can also make you more likely to get hardening of the arteries, or atherosclerosis, which can lead to heart attacks and strok Continue reading >>

How Common Is Type 1 Diabetes?
Type 1 diabetes affects about 1 million people in the United States. It used to be called juvenile diabetes or insulin-dependent diabetes. It's usually first diagnosed in young people but it can occur at any age. Type 1 diabetes is much less common than type 2 diabetes. The onset of type 1 diabetes, also referred to as juvenile diabetes, usually occurs in children or young adults. About 0.2 percent of people aged 20 years and younger have been diagnosed with type 1 diabetes in the United States. However, the onset of this disease can occur at any age. Over 23 million adults in America have been diagnosed with diabetes, with type 1 diabetes accounting for about 5 -10 percent of these cases. Continue reading >>

About Type 1 Diabetes
About type 1 diabetes Type 1 diabetes isn’t caused by poor diet or an unhealthy lifestyle. In fact, it isn’t caused by anything that you did or didn’t do, and there was nothing you could have done to prevent it. What is type 1 diabetes? Type 1 diabetes is an autoimmune condition. For reasons we don’t yet fully understand, your immune system – which is meant to protect you from viruses and bacteria – attacks and destroys the insulin-producing cells in your pancreas, called beta cells. Insulin is crucial to life. When you eat, insulin moves the energy from your food, called glucose, from your blood into the cells of your body. When the beta cells in your pancreas fail to produce insulin, glucose levels in your blood start to rise and your body can’t function properly. Over time this high level of glucose in the blood may damage nerves and blood vessels and the organs they supply. This condition affects 400,000 people in the UK, with over 29,000 of them children. Incidence is increasing by about four per cent each year and particularly in children under five, with a five per cent increase each year in this age group over the last 20 years. What causes type 1 diabetes? More than 50 genes have been identified that can increase a person’s risk of developing type 1 diabetes, but genes are only part of the cause. Scientists are also currently investigating what environmental factors play a role. What is known is that: Destruction of insulin-producing beta cells is due to damage inflicted by your immune system Something triggered your immune system to attack your beta cells Certain genes put people at a greater risk of developing type 1 diabetes, but are not the only factors involved While there are no proven environmental triggers, researchers are looking for po Continue reading >>

Common Questions About Type 1 Diabetes
Answers to your questions from Joslin Diabetes Center, the world leader in diabetes treatment and research. What is type 1 diabetes? In type 1 diabetes (formerly called 'juvenile-onset' or 'insulin-dependent'), the pancreas completely stops producing any insulin, a hormone that enables the body to use glucose (sugar) found in foods for energy. Instead of the body converting glucose into energy, it backs up in the blood stream and causes a variety of symptoms, including fatigue. Type 1 diabetes is different from type 2 diabetes because it is treatable only with insulin, delivered either via multiple syringe injections subcutaneously (under the skin) or through an insulin pump. Many of the symptoms of type 1 diabetes, however, are also those of type 2. Your doctor will perform a test to determine your pancreatic function and confirm a diagnosis. What causes type 1 diabetes? The cause of type 1 diabetes is still unknown, although many have speculated that it is a combination of genetic predisposition and environmental factors such as viruses that serve as the catalyst for the disease’s onset. Who gets type 1 diabetes? You can have type 1 diabetes at any point that your pancreas completely ceases to produce insulin to regulate glucose levels, although most people diagnosed with type 1 diabetes are usually children or young adults. How is type 1 diabetes treated? Unlike some people with type 2 diabetes who use insulin when diabetes pills have not been effective at regulating their glucose levels, people with type 1 can never use pills. The goal of insulin therapy is to mimic the way the pancreas would produce and distribute its own insulin, if it were able to produce it. One of the key factors in Joslin’s treatment of diabetes is tight blood glucose control, so be certai Continue reading >>

Diabetes Type 1
Type 1 diabetes tends to start when people are under 25, although it can be diagnosed later in life. With Type 1 diabetes (also called insulin-dependent or juvenile diabetes) the body's immune system destroys, or attempts to destroy, the cells in the pancreas that produce insulin. Insulin is the hormone that allows glucose to enter the cells of the body to provide fuel. When glucose can't enter the cells, it builds up in the blood and the body's cells literally starve to death. Everyone with Type 1 diabetes must take daily insulin injections and regularly monitor their blood glucose levels. The cause of Type 1 diabetes is unknown but it is thought to be an autoimmune disease, where the body's immune system destroys the cells in the pancreas that produce insulin. Not all diabetes in children and teenagers is the kind called Type 1. Type 2 diabetes is being seen increasingly in young people. Where Type 1 diabetes always requires insulin, Type 2 can require insulin but often it can be treated with other medicines such as tablets. This section deals only with young people who have Type 1 diabetes. We have talked to a range of young people who've lived with Type 1 diabetes from those who were very young when they were first diagnosed to those who were diagnosed when they were teenagers. We have also talked to some young people only recently diagnosed. In this section young people talk about the signs and symptoms that prompted them to seek medical help. Signs of diabetes Most people remembered that the first symptoms of diabetes had crept up on them over weeks or even months- most had felt thirsty all the time and said that they started to drink more and more and found that they were unable to quench their thirst. Lots of people described realising something must be wrong wi Continue reading >>