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How Can Diabetes Lead To Kidney Failure

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How Diabetes Leads To Kidney Disease

Diabetes is a disease characterized by high blood sugar and the body’s inability to produce or process proper amounts of insulin. As of 2015, the International Diabetes Federation reported an average of over 400 million people living with diabetes worldwide. Given poor diet and lifestyle choices, the number of people affected by diabetes (especially type 2) is on a rapid rise. Many people suffering from prediabetes, or impaired glucose intolerance, aren’t even aware of their condition. When the body experiences constant high levels of blood sugar, the small, intricate blood vessels of the kidneys can suffer severe damage. Once these vessels are damaged, the kidneys are no longer able to efficiently filter waste. This results in kidney damage caused by diabetes, a condition known as diabetic nephropathy. About 40 percent of insulin-dependent diabetics eventually develop diabetic nephropathy. Diabetic Nephropathy Symptoms During the early stages of diabetic nephropathy, you may not experience any noticeable symptoms. As the disease progresses and kidney function is diminished, blood pressure rises. This leads to swelling of the feet, ankles, and legs. Nausea and loss of appetite Continue reading >>

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  1. Allison Stasiuk

    I'd recommend none if you have diabetes, kidney disease, high blood pressure or are on medications like ACEIs (ends in "pril", ramipril, perindopril etc.) or ARBs (the "sartans", telmisartan, irbesartan etc.) Since it can lead to kidney failure as well as increased risk of cardiovascular events (small but significant risk), such as heart attack and strokes.
    But if you're young and healthy, watch your stomach lining (these meds can cause ulcers, and stomach bleeds), but otherwise it should be safe.

  2. Catherine Oates

    It depends on what you're taking it for. The bottle gives dosage instructions, but don't use it to mask pain that might be telling you that something needs to be addressed.

  3. Joshua Carr

    I've interpreted this question in a different way to the others here.
    An Ibuprofen overdose is quite an impressive feat. The average man would have to take roughly 150 200mg tablets to overdose and toxic effects are not likely below 100mg/kg. If you start to even come near such a high dose you will begin to feel very ill as the ibuprofen messes with your stomach.
    I imagine the answer you're looking for is one that's already been provided but I thought I'd provide this one too. Just in case!

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