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How Are Diabetes And Periodontal Disease Related

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Diagnostic Biomarkers Related To Periodontal Disease Activity In Diabetic

The purpose of the study was to monitor the activity of periodontal disease and suggest potential biomarkers related to active periodontal disease in patients with chronic periodontitis (PD) associated or not with type 2 diabetes mellitus (DM), based on the evaluation of the profile of gene expression of periodontal sites and the evaluation of inflammatory salivary proteins. Two hundred and five periodontal patients were enrolled, but only 41 exhibited ≥ 1 mm attachment loss in at least three periodontal site (active sites) 2 months after non-surgical periodontal therapy. The final sample was: 21 patients with chronic periodontitis (PD group) and 20 with chronic periodontitis and diabetes (PD+DM group). Fifteen periodontal- and systemically healthy patients were included as control group. Saliva collection, glycated hemoglobin measurement, periodontal examination and radiographs were conducted before and 2 months after non-surgical periodontal therapy. Radiographic subtraction was performed from pairs of the radiographs. Measurements of the areas with density loss were recorded. Gingival biopsies of active and non-active sites with similar clinical parameters were harvested for R Continue reading >>

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Popular Questions

  1. Endran Ratnasothy

    Periodontal disease can be a consequence of genetic factors and other medical conditions, that are not within our control.
    However good oral hygiene, regular dental check ups and avoiding bad habits like smoking/chewing betel nut will help a great deal in keeping periodontal disease at bay.
    Also a balanced diet, with all the macro and micro nutrients are helpful.
    To get down to details,
    Proper brushing technique, proper brush, and brushing twice a day.
    Flossing, at least once a day.
    Routine dental check ups, scaling twice a year or at least once a year

    Avoiding bad habits, like smoking.

    Hope this helps!

  2. Andrew Terry

    Floss, floss, floss.
    Really, flossing is the one thing I never took seriously, until my gums were receding and I had deep pockets between my gums and teeth. I had to have two root scrapings to clean up the deep pockets, and I now floss religiously.
    The reason I used to avoid flossing is because I hated sticking my fingers in my mouth. I now use the plastic floss picks instead. This may not be “as good” as string floss but it does the job.

    My understanding is the most important aspect of flossing is that it prevents the bacteria in the plaque on your teeth from establishing a blood supply with your gums which allows the bacteria to grow. When you run the floss between your teeth and gums it breaks any formation of blood supply, this is why your gums bleed if you don’t floss regularly, the bleeding is from breaking the blood supply to the bacteria. This bacteria left unchecked is what causes periodontal disease.

  3. Don Davis

    Here are the two remedies / preventatives that I know of:

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